KR20080048923A - 소화관에의 자극성을 감소한 경구 고형 조성물 - Google Patents

소화관에의 자극성을 감소한 경구 고형 조성물 Download PDF

Info

Publication number
KR20080048923A
KR20080048923A KR1020070113515A KR20070113515A KR20080048923A KR 20080048923 A KR20080048923 A KR 20080048923A KR 1020070113515 A KR1020070113515 A KR 1020070113515A KR 20070113515 A KR20070113515 A KR 20070113515A KR 20080048923 A KR20080048923 A KR 20080048923A
Authority
KR
South Korea
Prior art keywords
drugs
water
solid composition
oral solid
drug
Prior art date
Application number
KR1020070113515A
Other languages
English (en)
Korean (ko)
Inventor
노부오 미야다이
요이치 오누키
마사고 이시카와
미노루 오카다
히데요시 칸베
료 치바
Original Assignee
에스에스 세야쿠 가부시키 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에스에스 세야쿠 가부시키 가이샤 filed Critical 에스에스 세야쿠 가부시키 가이샤
Publication of KR20080048923A publication Critical patent/KR20080048923A/ko

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020070113515A 2006-11-29 2007-11-08 소화관에의 자극성을 감소한 경구 고형 조성물 KR20080048923A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JPJP-P-2006-00321343 2006-11-29
JP2006321343A JP5676834B2 (ja) 2006-11-29 2006-11-29 消化管への刺激性を減少した経口固形組成物

Publications (1)

Publication Number Publication Date
KR20080048923A true KR20080048923A (ko) 2008-06-03

Family

ID=39485502

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020070113515A KR20080048923A (ko) 2006-11-29 2007-11-08 소화관에의 자극성을 감소한 경구 고형 조성물

Country Status (5)

Country Link
JP (1) JP5676834B2 (ja)
KR (1) KR20080048923A (ja)
CN (1) CN101190206B (ja)
HK (1) HK1118208A1 (ja)
TW (1) TW200824710A (ja)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0517372A (ja) * 1991-07-10 1993-01-26 Yoshitomi Pharmaceut Ind Ltd 不快な味が軽減された生薬配合組成物
CN1100306A (zh) * 1994-05-30 1995-03-22 吴秀清 复方葡萄糖酸锌胶囊、片剂、口含片及其制备方法
JP2894955B2 (ja) * 1994-07-25 1999-05-24 ロート製薬株式会社 イブプロフェン製剤
JP3667381B2 (ja) * 1995-03-27 2005-07-06 株式会社資生堂 解熱鎮痛剤
SK284690B6 (sk) * 1997-06-11 2005-09-08 The Procter And Gamble Company Ústna dávkovacia forma na zvýšenie ochrany horného tráviaceho traktu
US6767899B1 (en) * 2000-08-29 2004-07-27 Leiner Health Services Corp. Composition and method for treatment of conditions having an inflammatory component
CN1507862A (zh) * 2002-12-19 2004-06-30 洁 严 复方对乙酰氨基酚维生素c分散片及其制造方法
JP3774814B2 (ja) * 2003-09-26 2006-05-17 小林製薬株式会社 システイン類の不快な臭気又は味が軽減された組成物
JP4210615B2 (ja) * 2004-03-26 2009-01-21 エスエス製薬株式会社 不快な味がマスキングされた製剤
EP1781253A1 (en) * 2004-07-01 2007-05-09 Warner-Lambert Company LLC Preparation of pharmaceutical compositions containing nanoparticles
PL1781277T3 (pl) * 2004-07-07 2012-07-31 Aft Pharmaceuticals Ltd Kompozycja łączona zawierająca ibuprofen i paracetamol
GB0420016D0 (en) * 2004-09-09 2004-10-13 Leuven K U Res & Dev Controlled release oral delivery system
JP4754211B2 (ja) * 2004-12-28 2011-08-24 ライオン株式会社 粒状医薬組成物及びその製造方法

Also Published As

Publication number Publication date
JP2008133234A (ja) 2008-06-12
TW200824710A (en) 2008-06-16
HK1118208A1 (en) 2009-02-06
CN101190206B (zh) 2013-04-24
CN101190206A (zh) 2008-06-04
JP5676834B2 (ja) 2015-02-25

Similar Documents

Publication Publication Date Title
ES2229483T3 (es) Composiciones farmaceuticas para la liberacion controlada de sustancias activas.
JP2019081789A (ja) 口腔内崩壊錠
KR101612137B1 (ko) 구강 내 붕괴정
US20130172374A1 (en) Solid composition for controlled release of ionizable active agents with poor aqueous solubility at low ph and methods of use thereof
KR101400064B1 (ko) 건식 직타 속붕괴성 정제
US20100086495A1 (en) Compositions and methods for enhancing transmucosal delivery
KR20040004638A (ko) 의약 조성물
KR20030097892A (ko) 의약 배합제
JP2002179558A (ja) 固形製剤
EP2074990B1 (en) Controlled release flurbiprofen and muscle relaxant combinations
JP2006001920A (ja) 医薬製剤
JP2010053043A (ja) 口腔内速崩壊錠
JP5168712B2 (ja) ナテグリニド含有製剤
JP5201837B2 (ja) 口腔内速崩壊錠
JPWO2020090970A1 (ja) 抗腫瘍剤を含む医薬組成物
JPH1135486A (ja) 薬用固形製剤
KR101046789B1 (ko) 안정성이 개선된 암로디핀 속붕해성 정제 및 그의 제조방법
CN1771915A (zh) 一种用于治疗儿童感冒的氨酚麻美口腔崩解片及制备方法
KR20080048923A (ko) 소화관에의 자극성을 감소한 경구 고형 조성물
KR20220027194A (ko) 신규 이부프로펜 및 아세트아미노펜 조성물
JP5054966B2 (ja) 固形製剤
TW200826962A (en) Oral solid composition masking bitterness
CN100387226C (zh) 一种千金藤素口腔崩解片及其制备方法
JP2014055187A (ja) 消化管への刺激性を減少した経口固形組成物
JP5226732B2 (ja) 催眠用圧縮成型製剤

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application