KR20080016224A - Cosmetic composition for anti-aging and improvement of skin comprising plant extract - Google Patents

Abstract

A composition comprising a plant mixture extract is provided to inhibit the damage of skin cell DNA, show the cell activity effect through skin cell proliferation and excellent fine skin texture increasing effect through skin cell proliferation without side effects, thereby being usefully used as a cosmetic composition providing excellent skin anti-aging and improving effects. A cosmetic composition for preventing and improving skin aging comprises 0.1-20.0 wt.% of at least one plant extract selected from the group consisting of an extract of Chaparral, an extract of Adenophora stricta, and an extract of Lupinus albus. The extract is prepared by extracting a mixture of Chaparral, Adenophora stricta and Lupinus albus with at least one solvent selected from the group consisting of distilled water, 1,3-butylene glycol, propylene glycol, C1-5 alcohol, and a mixture solvent thereof and the filtering the extract.

Description

COSMETIC COMPOSITION FOR ANTI-AGING AND IMPROVEMENT OF SKIN COMPRISING PLANT EXTRACT}

1 is a copy of the photograph of the cells of the hairless mouse (hairless mouse) in order to evaluate the skin cell DNA damage inhibitory effect (Experimental Example 4) of the cosmetic composition according to an embodiment of the present invention.

The present invention relates to a cosmetic composition for preventing skin aging and improving skin, and more particularly, to a cosmetic composition having excellent skin cell DNA damage suppression, cell activity effect, and fine skin texture increase effect by containing a longevity plant mixed extract. .

Human skin is an important organ that acts as a barrier to protect the human body from the external environment, and the smallest units that make up the cells breathe, create, and heal themselves, leading to the healthiest state. However, cells are exposed to external stimuli, one of the most dangerous of which is ultraviolet.

Ultraviolet rays can be divided into three regions, A, B, and C, depending on their wavelength. Among them, the most energetic and harmful ultraviolet C region is mostly absorbed by the ozone layer and does not reach the earth's surface. Ultraviolet A, which can reach deep within the skin, is relatively weak in energy and weak to cause great harm to the human body. However, ultraviolet B causes serious damage to skin cells' lipids, proteins and DNA. In particular, when the intracellular DNA is damaged by ultraviolet light B, apoptosis, mutations, and the like, the skin accelerates aging, deteriorates the skin function, and the skin becomes rough.

Accordingly, one of the areas of interest in cosmetics is how to delay skin aging. Thus, since the bad effect on the skin of ultraviolet rays has been emphasized, in the past, sunscreens and the like have been used in combination with cosmetics, but sunscreens have a disadvantage in that the safety (safety), etc. when blending in the cosmetics is not good.

On the other hand, fine skin texture measurement has recently been used as an indicator of the degree of condition of damaged skin due to aging. Fine skin texture is the outermost network structure of the skin, and the results of previous studies have shown that there is a significant change by age as a reliable indicator of skin aging. In view of this, fine skin texture can be said to reflect the condition in the skin. Therefore, it is possible to objectively determine the state of the skin by analyzing the state of fine skin texture by criteria (Photodermatol. Phoimmunol. Photomed. 19. 169-174, 2003).

It is an object of the present invention to provide a cosmetic composition containing a plant extract having excellent safety when formulated in a cosmetic and excellent skin aging prevention and fine skin texture improvement effect and low specific odor.

In order to achieve the above object, the present invention is Chaparral extract, Adenophora stricta extract, and Lupinus albus ) provides a cosmetic composition for preventing and improving skin aging comprising at least one plant extract selected from the group consisting of the extract as an active ingredient.

The inventors of the present invention, as part of a study to search for substances that have excellent safety (safety) when combined with cosmetics and excellent skin aging prevention and skin improvement effect, various effects on plant extracts that are predicted to be cosmetically effective in longevity plants As a result of a thorough investigation of the safety, it was found that the plant extract is excellent in preventing skin aging and improving skin, and has a specific odor and is safe for the skin.

In addition, the three longevity plants studied in connection with the present invention, chaparal, adenophora and lupine extract, inhibits skin cell DNA damage, prevents aging due to cellular activity and fine skin texture increase effect through skin cell proliferation. As a result of research on the effect and skin improvement effect, there are no reports related to the present invention. In the present invention, the present invention is demonstrated through the demonstration of the effect of inhibiting skin cell DNA damage, the effect of cell activity through skin cell proliferation and the effect of increasing the fine skin texture. It is complete.

In the present invention, 'celion' means a mixture of at least one long-life plant extract selected from the group consisting of chaparal extract, adenophora extract, and lupine extract.

Hereinafter, the present invention will be described in more detail.

The present invention provides an anti-aging and skin improvement composition containing a mixed extract of chaparal, adenophora and lupine. In the present specification, the anti-aging and skin improvement composition is a composition having a skin cell DNA damage suppression, a cell activity effect through skin cell proliferation and a fine skin texture effect.

Looking at the raw material of the Celion, which is a longevity plant mixed extract that is a cosmetic composition according to the present invention, first, Chaparral is known to live for several thousand years as an oak tree native to the desert southwestern United States. Korean Patent Laid-Open Publication No. 10-2005-0023041 discloses a stabilized composition containing chaparal extract, but this is for the purpose of improving the long-term stability of the destabilizing component in the cosmetic composition. It is completely distinguished from the effect of inhibiting the cell activity through skin cell proliferation and increasing the effect of fine skin texture.

On the other hand, Adenophora ( especially Adenophora) stricta ) is a perennial plant commonly found in Sanya and belongs to the bellflower family. Like wild ginseng, hundreds of years old are sometimes found and live long in grass. The root of adenophora is used as a detoxification and decontamination agent in oriental medicine (Korean Plant Flu, Haechangsa, 1993). In addition, a skin composition for skin whitening containing adenophora is described in Korean Patent No. 10-0544024, and it prevents skin dryness and prevents atopic and contact dermatitis symptoms (Korean Patent Publication No. 10-2004-0058848). Ho) is known. This is completely distinguished from the skin cell DNA damage inhibition of the present invention, the cell activity effect through skin cell proliferation and the effect of increasing the fine skin texture.

Lupineus ( Lupinus albus ) is a seed of subsidiary perennial grass, and the life span of polar lupine grows from 15 to hundreds of years, and these seeds are now germinating and flowering. It is a plant with strong vitality. According to a component identification study related to lupine, compounds such as lupine peptide have been studied and known to have collagenase and gelatinase inhibitory activity (Korean Patent Publication No. 10-2002-0030263). have. This is completely distinguished from the skin cell DNA damage inhibition of the present invention, the cell activity effect through skin cell proliferation and the effect of increasing the fine skin texture.

The cosmetic composition according to the present invention comprises at least one plant extract selected from the group consisting of three longevity plants, chaparal extract, adenophora extract, and lupine extract (hereinafter referred to as 'celion'), based on the total composition weight. It may include 0.1 to 20.0% by weight.

That is, in order to substantially expect the effect of inhibiting skin cell DNA damage, increasing cell activity through skin cell proliferation and increasing the effect of fine skin texture, it is preferable that the content of celion, which is a longevity plant mixed extract, is contained in an amount of 0.1 wt% or more. In consideration of the masking (masking) of the specific odor of the plant, it is preferably included in 20% by weight or less.

In addition, the cosmetic composition according to the present invention is obtained by extracting each plant for the constituent plants Chaparal, adenophora and lupine in order to make the celery and then mixing them, or by mixing together each plant to be prepared can do.

The extract of each plant used in the present invention is obtained by extracting seeds, bark, leaves, stems and shoots, etc., is an extract derived from nature and high in safety to the human body. Preferably, the adenophora extract is an adenophora root extract, and the lupine extract is a lupine fruit extract.

The plant extract can be obtained by an extraction method to obtain a plant extract, but is not limited in the present invention. For example, the roots, fruits and the like of the plant may be extracted with a solvent selected from the group consisting of, for example, distilled water, organic solvents and mixtures thereof, which are obtained by drying and grinding or cutting finely.

In this case, the organic solvent used may be 1,3-butylene glycol, lower alcohol having 1 to 4 carbon atoms, ethyl acetate or acetone, and may be used two or more kinds sequentially according to the polarity of the organic solvent.

For example, the plant extract is mixed with chaparal, adenophora and lupine in a weight ratio of 0.05 to 0.5: 0.2 to 2.0: 0.1 to 1.0 having distilled water, 1,3-butylene glycol, propylene glycol, 1 to 5 carbon atoms It is prepared by extraction with an alcohol or a mixed solvent of 5 to 30% by weight, preferably 10 to 25% by weight by cold dip extraction or supercritical extraction. The extract filtrate obtained at this time is filtered, dehydrated or desolvated, and then concentrated under reduced pressure or lyophilized and blended into the cosmetic composition in liquid or powder form. For example, the extract is prepared by filtration with a 0.1-1 μm filter, preferably a 0.2-0.5 μm filter.

The cosmetic composition of the present invention may be formulated into a cosmetic composition comprising a lotion, essence, lotion, cream or gel. More specifically, the cosmetic composition of the present invention may be provided for the use of basic cosmetics, makeup cosmetics, body cosmetics, hair cosmetics, scalp cosmetics, shaving cosmetics or oral cosmetics.

Examples of the basic cosmetics include creams, lotions, packs, massage creams, emulsions, and the like; The makeup cosmetics include foundation, makeup base, lipstick, eyeshadow, eyeliner, mascara, eyebrow pencil and the like; Body cosmetics include soaps, liquid detergents, bath agents, sunscreen creams, sun oils, and the like; Hair cosmetics include shampoo, rinse, hair treatment, hair mousse, hair liquid, pomade, hair colorant, hair bleach, color rinse; Cosmetics for the scalp include hair tonic and scalp treatments; Cosmetics for shaving include aftershave lotion and shaving cream; Cosmetics for oral use include toothpaste and mouse washers.

Hereinafter, the present invention will be described in detail through examples. However, these experimental examples, examples, comparative examples and production examples are only examples of the present invention, and the protection scope of the present invention is not intended to be limited thereto.

< Example  1> Plant Blend Extract Celence  Produce

Based on the total weight of the extraction system, longevity plants mixed with 2.0% by weight of chaparal, 9.0% by weight of adenophora, and 4.0% by weight of lupine were cooled by 85% by weight of the extraction solvent (distilled water: butylene glycol weight ratio = 7: 3). After extraction, the resultant was filtered with a 0.2 μm filter to prevent sediment, and then irradiated with ultraviolet (UV) light for 3 days for sterilization to obtain Celiac, which is a final mixed plant of longevity.

< Example  2> Plant Blend Extract Celence  Produce

On the other hand, 2.0% by weight of chaparal to 98% by weight of the extraction solvent (distilled water: butylene glycol weight ratio = 7: 3) relative to the total weight of the extraction system; 9.0 wt% of adenophora to 91 wt% of an extraction solvent (distilled water: butylene glycol weight ratio = 7: 3); Lupineus 4.0% by weight of the extraction solvent (distilled water: butylene glycol weight ratio = 7: 3), respectively, extracted by cold extraction, filtered with a 0.2 ㎛ filter to prevent the formation of precipitates, and then UV (UV) for 3 days for sterilization Each of the chaparal extract, adenophora extract, and lupine extract were obtained.

< Experimental Example  1> Cytotoxicity Test

In order to verify the primary safety as a raw material used in cosmetics, MTT test was performed by culturing V79-4 cells (Chinese hamster, continuous cell line of lung tissue fibroblasts) against the celions prepared in Example 1 [ References: Mossman T. (1983) Rapid colorimetric assay for cellular growth & survival: application to proliferation & cytotoxicity assays. Journal of Immunological Methods 65, 55 ~ 63]. The cytotoxicity test results are shown in Table 1.

sample ^a IC ₅₀ (%, w / v) Sodium Lauryl Sulfate (SLS) 0.005 Squalane 0.05 Celence 10.0

Note) ^a IC _50: inhibitory concentration (Inhibitory Concentration) 50, the concentration that kills 50% of cells

As shown in Table 1, the IC ₅₀ value of the celery, which is a mixed extract of longevity plants, was 10.0, showing a cytotoxicity over 2000 times lower than that of sodium lauryl sulfate, and 200 compared to squalane, which is an excellent safety material. More than twice the cytotoxicity is low, it can be seen that the safety is very good.

< Experimental Example  2> allergy  evaluation( LLNA )

In order to confirm the allergy-induced celence according to the present invention, an experimental method using acetone: olive oil (4: 1) as a carrier medium was selected [Kimber I (1990): Identification of contact allergens using the murine local lymph node assay, J. Appl . Toxicol . 10 (3), 173 to 180]. A 20%, 40%, and 60% solution of the plant extract was prepared and applied to both ears of the mouse (Balb / c) for 50 days for 3 days, and then isolated from the rat lymph node (Auricular lymph node). Lymph nodes were pulverized into a single cell state and then cultured for 24 hours with the addition of radioisotope (3H-thymidine), and the amplification degree [cpm] of the cells was measured. The results are shown in Table 2.

sample Lymph node cells (10 ⁷ cells / ml) cpm (average) Amplification Acetone: Olive Oil (4: 1) 1.70 2720 Transportation Cerence 20% 1.75 2176 0.8 Celion 40% 2.04 2992 1.1 Celion 60% 3.02 3264 1.2

As shown in Table 2, the celery of the longevity plant mixed extract according to the present invention has an amplification degree (S.I) of 2 or less, and it has been shown that there is little possibility of allergy.

< Experimental Example  3> Evaluation of skin cell DNA damage inhibition (in vitro)

The effect of inhibiting DNA damage caused by UV light in normal skin keratinocytes of cultured humans against the celions, chaparrel extracts, adenophora extracts and lupine extracts according to the present invention was tested by the comet assay. In cultured normal human keratinocytes, celions were treated at various concentrations, and chaparel extract, adenophora extract, and lupine extract were treated at 0.1% concentration for 12 hours, and then cultured and discarded PBS. The cells were harvested and irradiated with UVB 60mJ with an ultraviolet irradiator, and the cells were harvested to measure DNA damage at the cellular level.

In the case of DNA strand breakage in nucleophiles, electrophoresis moves toward the anode (+ pole) to show a tail that extends from its original structure, making it easy to detect DNA damage during electrophoresis. . The mean of the tail moment values of 50 randomly selected cells was calculated to be the degree of DNA damage of a specific sample.

Inhibition rate = [(UV irradiation control-experimental group) / UV irradiation control] × 100

Inhibition rate (%) was calculated by the above formula and the results are summarized in Table 3.

sample Tail moment % Inhibition Negative control 0.790 - UV irradiation control 9.466 - Cerence 0.0001% 8.011 15.4 Cerence 0.001% 7.810 17.5 Celion 0.01% 7.659 19.1 Celion 0.1% 7.490 20.1 Chaparel Extract 0.1% 8879 6.2 Adenophora Extract 0.1% 9134 3.5 Lupine extract 0.1% 8892 5.0

As can be seen from the results of Table 3, the celery, which is a long-life plant mixed extract obtained according to the embodiment, showed a skin cell DNA damage inhibitory effect of 15.4% or more and 20.1% at a concentration of 0.0001% to 0.1%, while 0.1% At the concentrations, Chaparel extract was 6.2%, Adenophora extract 3.5%, Lupine extract 5.0% inhibition rate was found that the longevity plant mixture extract Celion has a synergistic effect of 5.4% at 0.1% concentration.

< Experimental Example  4> Evaluation of skin cell DNA damage inhibition (in vivo )

Inhibition of skin DNA damage caused by UV light using hairless mouse for celine, chaparal extract, adenophora extract, and lupine extract with excellent DNA damage suppression effect on skin cells Was tested by the comet assay.

After applying celine at various concentrations to the back of the hairless mice for 6 days, UVB 1J is irradiated with an ultraviolet irradiator. Skin was isolated to isolate cells and measure DNA damage. Electrophoresis in the presence of DNA strand breakage in a nucleophile allows for easy detection of DNA damage during electrophoresis by moving towards the anode (+ pole) to show a tail that extends from its original structure. have. The mean of the tail moment values of 50 randomly selected cells was calculated to be the degree of DNA damage of a specific sample. The results are summarized in FIG.

Inhibition rate = [(UV irradiation control-experimental group) / UV irradiation control] × 100

Inhibition rate (%) was calculated by the above formula and the results are summarized in Table 4.

sample Tail moment % Inhibition Negative control 2.752 - UV irradiation control 24.348 - Celion 0.01% 19.363 20.5 Celion 0.1% 17.930 26.3 Cerence 1% 15.968 34.4 Chaparel Extract 1% 21,938 9.9 Adenophora Extract 1% 23,130 5.0 Lupine extract 1% 22,595 7.2

As can be seen in Figure 1 and Table 4, the longevity plant mixed extract celions can be seen that even in the skin of live hairless mice very effectively prevent DNA damage in the skin cells by ultraviolet light. This means that the celions can be applied not only to cultured cells but also to the skin of living organisms, which can show strong DNA damage prevention effect.

< Experimental Example  5> cell proliferation effect

Experiments were performed to determine the cell proliferation effect of celence according to the present invention. First, human fibroblast cells were inoculated into 96 well plates (Corning, Inc.), and then incubated. , MTT test method was performed to evaluate cell proliferation. Serum 1% was added as a control and serum-free medium was used as a comparative group. The results are shown in Table 5.

Type of sample Cell proliferation rate (%) Control (serum 1%) 180 Cerence 10% 154 Cerence 1% 136 Celion 0.01% 126 Cerence 0.001% 110

As shown in the results of Table 5, it can be seen that the celery, which is a longevity plant mixed extract according to the present invention, has a very good cell proliferation effect.

< Example  3 to 5> and < Comparative example  1 to 3

According to the composition of Table 6, Examples 3 to 5 were combined with the longevity plant mixture extract Celion prepared in Example 1 in a general manner.

Comparative Examples 1 to 3 are comparative samples containing chaparal extract, adenophora extract, and lupine extract, respectively, to prepare an oil-in-water emulsion according to the following method: The oil phase was added to the aqueous phase, emulsified under homomixer under 6000 rpm for 10 minutes, and cooled to 30 ° C to prepare an oil-in-water emulsion.

Units of numerical values used in Table 6 below are in weight percent.

division ingredient Example 3 Example 4 Example 5 Control Comparative Example 1 Comparative Example 2 Comparative Example 3   Awards Purified water To 100 To 100 To 100 To 100 To 100 To 100 To 100 Triethanolamine 0.15 0.15 0.15 0.15 0.15 0.15 0.15 Carboxy vinyl polymer (1 wt% solution) 15 15 15 15 15 15 15 Dark glycerin 6 6 6 6 6 6 6 Propylene glycol 6 6 6 6 6 6 6 Methylparaben 0.2 0.2 0.2 0.2 0.2 0.2 0.2 Celence 0.1 1.0 10.0 - - - - Chaparel Extract - - - - 10 - - Adenophora Extract - - - - - 10 - Lupine extract - - - - - - 10   Yu Sang Cetostearyl alcohol One One One One One One One Glyceryl Monostearate One One One One One One One Sorbitan monosulfate One One One One One One One POE (20) sorbitan monostearate 1.5 1.5 1.5 1.5 1.5 1.5 1.5 Eichparaben 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Isocetil Myristate 5 5 5 5 5 5 5 Isocetyloctanoate 5 5 5 5 5 5 5 Squalane 5 5 5 5 5 5 5 Spices Quantity Quantity Quantity Quantity Quantity Quantity Quantity

In Table 6, Carbopol 941 (Carbopol 941), a product of B.F.Goodrich, was used as a 1% by weight aqueous solution. The monostearate sorbitan was used under the trade name Alascel 60 of IIC Co., Ltd., UK, and isocetyloctanoate was manufactured by Nihon Kokyu Alcohol Co., Ltd. Was used.

< Experimental Example  6> fine Skin texture  Increase effect

The effects of increasing the fine skin texture of the products prepared according to Examples 3 to 5 and Comparative Examples 1 to 3 were evaluated as follows. That is, each sample was applied twice a day to 20 women aged 30 to 45 years, evenly applied to four sites of 2.5 cm × 2.5 cm in the lower arm of the arm for 2 weeks. Two weeks later, after application of the sample, the skin skin replica was evaluated by measuring the amount of fine skin texture by image analysis. The results of the image analysis are shown in Table 7 as the amount of fine skin texture after application of the sample to the application of the sample.

division Fine skin texture growth rate (%) Control 2.50 Example 3 5.42 Example 4 7.40 Example 5 12.39 Comparative Example 1 3.0 Comparative Example 2 2.8 Comparative Example 3 4.0

As can be seen from the measurement results of the fine skin texture by the image analysis of Table 7, the depth of the fine skin texture increased by 2.50% in the case of the control group, while the plants of Examples 3 to 5 to which the mixture of longevity plant mixed extract was added 5.4 to 12.4% was increased according to the extract concentration, showing an effective fine skin texture increase effect compared to the control.

On the other hand, chaparal extract showed a 3.0% increase, and adenophora extract showed a 2.8% increase, showing little difference compared to the control, and the lupine extract showed a 4.0% increase.

Accordingly, it was confirmed that the preparation containing celion, a long-lived plant extract, has an effect on skin improvement, and no other side effects or skin deterioration were observed.

< Production Example  1> lotion

The lotion containing the celence of the present invention was manufactured according to the conventional lotion preparation method by the prescription of Table 8.

Raw material name Weight% (w / w)   glycerin 5.0   Dipropylene glycol 3.0   Hyaluronic acid 0.5   Polyoxyethylene Cured Castor Oil 0.1   Polyethylene oleylethyl 0.1   ethanol 5.0   antiseptic 0.15   Spices Quantity   Color Quantity   Celence 0.1   Purified water To 100

< Production Example  2> essence

The essence containing the celence of this invention was prepared according to the conventional essence manufacturing method by the prescription of Table 9.

Raw material name Weight% (w / w)   Cetostearyl alcohol One   Self-emulsifying monostearic acid One   Beeswax 0.5   Squalane 5   Isocetyloctanoate 3   Dimethylsiloxane 0.3   Sorbitan monosulfate 0.5   Monostearic Acid Polyethylene Glycol 8   glycerin 4   Propylene glycol 0.2   Carboxy Polymer 0.22   Triethanolamine 0.25   antiseptic Quantity   Spices Quantity   Color Quantity   Celence 15   Purified water To 100

< Production Example  3> lotion

The lotion containing celence of this invention was prepared according to the conventional lotion manufacturing method by the prescription of Table 10.

Raw material name Weight% (w / w)   Cetostearyl alcohol 0.8   Self-emulsifying monostearic acid One   Wax 0.5   Stearic acid 0.5   Liquid paraffin 7   Squalane 5   Macadamia Oil 3   Isocetyloctanoate 2   Dimethylsiloxane 0.3   Sorbitan monosulfate 0.5   Monostearic Acid Polyethylene Glycol 1.2   glycerin 4   Propylene glycol 4   Betaine 4   Carboxy Polymer 0.12   Triethanolamine 0.15   Preservative 0.25   Spices Quantity   Color Quantity   Celence 5   Purified water To 100

< Production Example  4> cream

In the formulation of Table 11, according to the conventional cream preparation method, a cream containing celence of the present invention was prepared.

Raw material name Weight% (w / w)   Cetostearyl alcohol 3   Self-emulsifying monostearic acid 1.5   Lipophilic monostearic acid 1.5   Wax 0.5   Liquid paraffin 8   Squalane 7   Isocetyloctanoate 4   Purified Jojoba Oil 4   Dimethylsiloxane 0.3   Sorbitan monosulfate One   Monostearic Acid Polyethylene Glycol 1.2   glycerin 6   Propylene glycol 4   Betaine 4   Xanthan Gum 0.06   Triethanolamine 0.1   antiseptic 0.25   Spices Quantity   Color Quantity   Celence 10   Purified water To 100

< Production Example  5> gel

In the formulation of Table 12, according to the conventional gel preparation method, a gel containing celence of the present invention was prepared.

Raw material name Weight% (w / w)   glycerin 4   Propylene glycol 4   ethanol 10   Polyoxyethylene Cured Castor Oil 0.1   Carboxy Polymer 0.3   Triethanolamine 0.3   antiseptic Quantity   Spices Quantity   Color Quantity   Celence One   Purified water To 100

As described above, the cosmetic composition of the present invention containing celinus, which is a mixed extract of the longevity plant, is excellent in inhibiting skin cell DNA damage, improving cell activity, and increasing fine skin texture, while improving skin side effects and skin deterioration. There is an advantage that does not cause.

Claims (3)

Chaparral Extract, Adenophora stricta ) Extract, and Lupineus ( Lupinus albus ) cosmetic composition for preventing and improving skin aging comprising at least one plant extract selected from the group consisting of the extract as an active ingredient 0.1 to 20.0% by weight based on the total composition. The method of claim 1, wherein the plant extract is chaparal, adenophora and lupine in a weight ratio of 0.05 to 0.5: 0.2 to 2.0: 0.1 to 1.0, distilled water, 1,3-butylene glycol, propylene glycol, carbon number A skin composition for preventing and improving skin aging, characterized in that it is produced by extracting with one or more selected extraction solvents from the group consisting of alcohols of 1 to 5, and mixed solvents thereof and then filtering them. The cosmetic composition for preventing and improving skin aging according to claim 1, wherein the composition is a lotion, an essence, a lotion, a cream or a gel.

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