KR20080002867A - 펩티드 데포르밀라제 (ｐｄｆ) 억제제로서 유용한이미다조[1,2-ａ]피리딘 유도체 - Google Patents

펩티드 데포르밀라제 (ｐｄｆ) 억제제로서 유용한이미다조[1,2-ａ]피리딘 유도체 Download PDF

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Publication number
KR20080002867A
KR20080002867A KR1020077024438A KR20077024438A KR20080002867A KR 20080002867 A KR20080002867 A KR 20080002867A KR 1020077024438 A KR1020077024438 A KR 1020077024438A KR 20077024438 A KR20077024438 A KR 20077024438A KR 20080002867 A KR20080002867 A KR 20080002867A
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KR
South Korea
Prior art keywords
group
compound
atom
formula
hydrogen atom
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Ceased
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KR1020077024438A
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English (en)
Korean (ko)
Inventor
미카엘 토르만
Original Assignee
노파르티스 아게
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Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20080002867A publication Critical patent/KR20080002867A/ko
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020077024438A 2005-04-25 2006-04-24 펩티드 데포르밀라제 (ｐｄｆ) 억제제로서 유용한이미다조[1,2-ａ]피리딘 유도체 Ceased KR20080002867A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005019181A DE102005019181A1 (de) 2005-04-25 2005-04-25 Peptid-Deformylase (PDF) Inhibitoren 1
DE102005019181.9 2005-04-25

Publications (1)

Publication Number Publication Date
KR20080002867A true KR20080002867A (ko) 2008-01-04

Family

ID=36692610

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077024438A Ceased KR20080002867A (ko) 2005-04-25 2006-04-24 펩티드 데포르밀라제 (ｐｄｆ) 억제제로서 유용한이미다조[1,2-ａ]피리딘 유도체

Country Status (12)

Country Link
US (2) US7662833B2 (enExample)
EP (1) EP1877408A1 (enExample)
JP (1) JP2008538778A (enExample)
KR (1) KR20080002867A (enExample)
CN (1) CN101163703B (enExample)
AU (1) AU2006239548B8 (enExample)
BR (1) BRPI0609946A2 (enExample)
CA (1) CA2605925A1 (enExample)
DE (1) DE102005019181A1 (enExample)
MX (1) MX2007013225A (enExample)
RU (1) RU2420526C2 (enExample)
WO (1) WO2006114263A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160044222A (ko) 2014-10-15 2016-04-25 장준구 다각도로 발광하는 led패키지

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008068392A1 (fr) * 2006-12-07 2008-06-12 Commissariat A L'energie Atomique Nouveaux derives fluorophores imidazo [1,2-a] pyridin-3-yl-amine et leur procede de preparation
WO2008141239A1 (en) * 2007-05-10 2008-11-20 Acadia Pharmaceuticals Inc. Imidazol [1,2-a] pyridines and related compounds with activity at cannabinoid cb2 receptors
DE102007040336A1 (de) 2007-08-27 2009-03-05 Johann Wolfgang Goethe-Universität Frankfurt am Main Neue Inhibitoren der 5-Lipoxygenase und deren Verwendungen
FR2925903B1 (fr) * 2008-01-02 2011-01-21 Sanofi Aventis DERIVES 6-HETEROCYCLIQUE-IMIDAZO°1,2-a!PYRIDINE-2- CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
WO2010032195A1 (en) * 2008-09-16 2010-03-25 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
CN101729939B (zh) * 2008-10-31 2012-12-05 中兴通讯股份有限公司 无源光网络带宽分配方法及系统
WO2011041713A2 (en) * 2009-10-02 2011-04-07 Glaxosmithkline Llc Piperazinyl antiviral agents
EP2601194B1 (en) * 2010-08-03 2016-05-25 Merck Sharp & Dohme Corp. Fused-imidazoyl compounds useful as antimicrobial agents
WO2012087833A1 (en) 2010-12-22 2012-06-28 Abbott Laboratories Hepatitis c inhibitors and uses thereof
SG11201400988SA (en) * 2011-10-21 2014-07-30 Glaxosmithkline Llc Compounds and methods for enhancing innate immune responses
CN107245050B (zh) * 2016-12-05 2019-10-25 徐州医科大学 香草醛异羟肟酸类衍生物及其应用
EP3750878B1 (en) 2019-06-14 2025-05-14 Vivoryon Therapeutics N.V. Heteroaromatic inhibitors of astacin proteinases

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
HU176214B (en) * 1977-05-18 1981-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new 5,6-dihydro-imidazo-square bracket-5,1-a-square bracket closed-isoquinolin derivatives
CA1164459A (en) * 1980-11-11 1984-03-27 Yung-Hsiung Yang Process for preparing (imidazo¬1,2-a|pyridine- 2-yl)-carbostyril or -3,4-dihydrocarbostyryl derivatives
JPS61218589A (ja) * 1985-03-26 1986-09-29 Eisai Co Ltd ５―（６―イミダゾ〔１，２―ａ〕ピリジニル）ピリジン誘導体
JPH0717971A (ja) * 1993-07-02 1995-01-20 Takeda Chem Ind Ltd イミダゾール誘導体、その製造法及び用途
CZ297278B6 (cs) * 1996-08-07 2006-10-11 Darwin Discovery Limited Deriváty hydroxamové a karboxylové kyseliny a jejich pouzití
AR029916A1 (es) * 2000-05-05 2003-07-23 Smithkline Beecham Corp N-formil-n-hidroxi-ariloxi alquilaminas y metodos para tratar infecciones bacterianas
DE10050663A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Verwendung von substituierten Imidazo[1,2-a]pyridin-, -pyrimidin- und pyrazin-3-yl-amin-Derivaten zur Herstellung von Medikamenten zur NOS-Inhibierung
TWI312347B (en) * 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
DE10150172A1 (de) * 2001-10-11 2003-04-30 Morphochem Ag Neue Verbindungen, die Protein Tyrosin Phosphatase 1B (PTP-1B) inhibieren
US20040127719A1 (en) * 2002-03-08 2004-07-01 Kexin Yang Alpha-isocyanocarboxylate solid support templates, method of preparation and for using the same
UY27813A1 (es) 2002-05-31 2003-12-31 Smithkline Beecham Corp Inhibidores de la peptido-desformilasa
US7442793B2 (en) * 2002-12-11 2008-10-28 Smithkline Beecham Corporation Peptide deformylase inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160044222A (ko) 2014-10-15 2016-04-25 장준구 다각도로 발광하는 led패키지

Also Published As

Publication number Publication date
EP1877408A1 (en) 2008-01-16
AU2006239548B2 (en) 2010-04-29
MX2007013225A (es) 2007-12-12
JP2008538778A (ja) 2008-11-06
AU2006239548B8 (en) 2010-08-26
CN101163703A (zh) 2008-04-16
BRPI0609946A2 (pt) 2010-05-11
CN101163703B (zh) 2010-12-15
CA2605925A1 (en) 2006-11-02
WO2006114263A1 (en) 2006-11-02
US20090215816A1 (en) 2009-08-27
DE102005019181A1 (de) 2006-10-26
RU2420526C2 (ru) 2011-06-10
RU2007143512A (ru) 2009-06-10
US20080188515A1 (en) 2008-08-07
US7662833B2 (en) 2010-02-16
AU2006239548A1 (en) 2006-11-02

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