KR20080001075A - Cosmetic composition for wrinkle care - Google Patents

Abstract

A cosmetic composition comprising the extracts of tropical fruits is provided to improve stability of tropical fruit extracts by microencapsulation, and minimize precipitation and discoloration of tropical fruit extracts by preventing reaction with ionic polymers, so that it is useful for improving skin wrinkles. A cosmetic composition for improving skin wrinkles comprises 0.1-20 wt.% of microcapsules containing the extracts of tropical fruits including gac, noni, camucamu, acai, goji, guanara, sea buckthorn and maca and having the size of 50 mum or less, and is prepared by (a) solubilizing water-insoluble cellulose derivatives in organic solvent and adding the tropical fruits to the solution to prepare the oil phase, (b) solubilizing water-soluble surfactant having 12 or more of HLB(hydrophile-lipophile balance) in water to prepare the water phase, (c) adding the oil phase into the water phase to prepare O/W(oil in water) type emulsion, and (d) drying the emulsion.

Description

Functional cosmetic composition for wrinkle improvement {COSMETIC COMPOSITION FOR WRINKLE CARE}

1 is a graph of fibroblast growth of the extract according to an embodiment of the present invention.

Figure 2 is a graph of collagen biosynthetic capacity of the extract according to an embodiment of the present invention.

Figure 3 is a transdermal absorption photograph of microcapsules according to an embodiment of the present invention.

Figure 4 is a SEM photograph of the microcapsules according to an embodiment of the present invention.

The present invention relates to a functional cosmetic composition for improving wrinkles, and more particularly, to improve the stability by improving the stability by microencapsulating the active ingredient fraction extract of tropical fruit can maintain the effect in a stable state for a long time It relates to a functional cosmetic composition for wrinkle improvement that can be minimized precipitation and discoloration reaction.

In general, the "wrinkling" of the skin can be said to be a change in the form and structure of the skin that is locally formed and settled in the site subjected to chronic deformation by muscle movement, and not only the physiological change but also the finer changes in the internal structure of the skin. It may be said that examining the wrinkle formation mechanism along with the change in physical properties is important for understanding the actual wrinkle formation mechanism.

In this regard, as skin internal structure changes due to photoaging, epidermis, thickening of the dermis, accumulation of abnormal elastic material, or three-dimensional structure change of elastic fibers have been reported. In addition, for collagen called skeleton, which is a major component of skin structure, microfiberization and weakening of fibrous form of collagen fibers have been revealed (Zheng P. and kligman LH, uvA-induced ultrastructural changes in hairless mouse skin: A comparison to uv B-induced damage., J. Invest.dermatol., 100,194-199 (1993)).

However, the collagen fiber bundles formed by these bundles are known to have a great influence on the toughness of the skin through the study of the wound healing process, etc., but the effects on the structural change, the physical properties of the skin and the wrinkle formation due to photoaging There has not been enough review so far.

The mainstream of the recent skin aging research is the study of the direct and indirect effects of sunlight due to the destruction of the ozone layer, and the effects of collagen fibers are actively used using various substances to measure the effect of wrinkles caused by the light. I am researching.

The present invention has been made to solve the problems of the prior art and to meet the demands of the technical field related to the present invention, the object of the present invention is to improve the wrinkles of the skin wrinkle improvement that can maintain the effect in a stable state for a long time It is to provide a functional cosmetic composition for.

In addition, another object of the present invention is to provide a functional cosmetic composition for improving wrinkles to minimize the precipitation and discoloration reaction by not easily react with other weak ionic polymers in the formulation when the tropical fruit extract is added.

Functional cosmetic composition for wrinkle improvement according to the present invention for achieving the above object is characterized in that it comprises a microcapsules stabilized tropical fruit extract.

Preferably, the tropical fruit extract is Gac, Noni, CamuCamu, Acai, Goji, Guarana, Sea Buckthron and Maca. It is characterized by containing an extract.

More preferably, the microcapsules are contained in an amount of 0.1 to 20% by weight based on the total weight of the cosmetic composition.

More preferably, the size of the microcapsules is 50 μm or less.

Also preferably, the microcapsules may comprise the steps of: (a) dissolving a water-insoluble cellulose derivative in an organic solvent and adding the tropical fruit extract to prepare an oil phase; (b) dissolving at least 12 hydrophile lipophil balance (HLB) water-soluble surfactants in water to prepare an aqueous phase; (c) emulsifying while adding an oil phase to the water phase to prepare an oil in water (O / W) emulsion; And (d) characterized in that the microcapsules prepared through the step of drying the emulsion.

More preferably, the water insoluble cellulose derivative is a water insoluble cellulose derivative selected from the group consisting of ethyl cellulose, cellulose acetate, cellulose acetate butyrate and cellulose acetate propionate, and the water soluble surfactant is a polyoxyethylene type non- It is characterized in that it is a water-soluble surfactant selected from the group consisting of an ionic surfactant, a polyhydric alcohol ester nonionic surfactant, and a polymeric surfactant.

Hereinafter, the present invention will be described in detail with reference to embodiments and drawings of the present invention. These examples are only presented by way of example only to more specifically describe the present invention, it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples. .

The present invention as a part of the research to overcome the problems such as stability and side effects of the conventional cosmetic composition and to find a better functional cosmetics, as a result of searching dozens of tropical fruits, found that it is effective in wrinkle improvement and the present invention It was completed.

In addition, in order to obtain a cosmetic having more effective anti-wrinkle, fractionation is performed on the basis of these extracts to obtain a blending ratio, and synergistic effects beyond the additive effect of each component that attempts to prepare a composite powder may be obtained. I figured it out.

The supercritical fluid extraction technology used in the functional cosmetic composition for wrinkle improvement according to the present invention is a certain substance becomes a fluid state after a certain high pressure and a high temperature (critical point). It is separated and purified with high purity.

Extraction by supercritical fluid uses a supercritical fluid near or above a critical temperature (Tc) and a critical pressure (Pc) as a solvent. The supercritical fluid exhibits the trade-off between gas and liquid properties. The density is close to the density of the liquid, the viscosity is close to the viscosity of the gas, and the diffusion coefficient is about 100 times greater than the diffusion coefficient of the liquid. Therefore, it shows high solubility and fast mass transfer rate. In addition, the solvent power can be freely controlled by simply changing the temperature and pressure or by using a modifier to selectively separate the target. Carbon dioxide is generally used as a supercritical fluid, which is easy to separate and purify a heat-stable material due to its low critical temperature. On the other hand, since the supercritical fluid solvent can be easily removed from the product to prevent the environmental pollution that is a problem when extracting the organic solvent and the price is low, it can be said to be a very environmentally and economical extraction method. That is, the advantage of supercritical extraction is, firstly, non-toxic to the skin because carbon dioxide, which is harmless to the human body, is used instead of the solvent. (No residual organic solvents and heavy metals) Second, it can deliver the freshness of natural plants and herbal medicines as it is processed at low temperatures. (Extension of activity, preventing degeneration due to heat) Third, biochemically stable by simplifying the extraction process as much as possible. (Oxygen Blocking, Microbial Contamination Prevention) Among the extracts obtained by supercritical extraction, only the active ingredients required for the present invention were obtained to the maximum, and then applied to the cosmetics by maintaining stabilization through microencapsulation.

In addition, the method for producing a microcapsule for encapsulating the active ingredient used in the present invention is disclosed in the patent application No. 2005-0031878 filed by the present applicant "Method of preparing a microcapsules using a water-insoluble cellulose derivative and a microcapsules prepared therefrom" It is noted that it can be produced by the method described in. For contents other than those described in the specification of the present invention, reference may be made to the contents in the patent application.

Briefly, the microcapsules according to the present invention comprise the steps of: (a) dissolving a water-insoluble cellulose derivative in an organic solvent and adding the tropical fruit extract to prepare an oil phase; (b) dissolving at least 12 hydrophile lipophil balance (HLB) water-soluble surfactants in water to prepare an aqueous phase; (c) emulsifying while adding an oil phase to the water phase to prepare an oil in water (O / W) emulsion; And (d) characterized in that the microcapsules prepared through the step of drying the emulsion.

The water-insoluble cellulose derivative is a water-insoluble cellulose derivative selected from the group consisting of ethyl cellulose, cellulose acetate, cellulose acetate butyrate and cellulose acetate propionate, the water-soluble surfactant is a polyoxyethylene type nonionic surfactant, It is preferable that it is a water-soluble surfactant chosen at least 1 type from the group which consists of a polyhydric-alcohol ester nonionic surfactant and a polymeric surfactant.

EXAMPLE

Example 1 Extraction of Each Active Ingredient (Supercritical Extraction)

First, 1,3BG (Butylene Glycol) and ethanol were mixed in the same mass ratio and stirred to form a single phase, which is used as a cosolvent to be used in the extraction process using supercritical carbon dioxide. Gac, Noni, CamuCamu, Acai, Goji, Guarana, Sea Buckthron and Maca until there is no change in weight It is dried and ground to a size of 0.3 cm or less using a grinder. The co-solvent is mixed with the pulverized material at a mass ratio of 1: 2 and stirred for 30 minutes, and then the mixture is put into a supercritical extraction tank having an internal volume of 1.5 L and sealed to increase the pressure by supplying carbon dioxide using a high pressure gas pump. The temperature inside the extraction tank is raised to 40 ° C at a rate of 0.5 ° C / min and maintained for 50 minutes. The extract was released while supplying carbon dioxide and decompressed at atmospheric pressure to separate carbon dioxide and its extract, and carbon dioxide was released into the atmosphere, and the extract was collected by a collector and used in the present invention.

Example 2 Preparation of Tropical Fruit Extract Mixtures

Each extract extracted in Example 1 was mixed in the same ratio, methanol was added thereto, refluxed for 5 hours, and distilled under reduced pressure to obtain 140 g of dry methanol extract, and the extract was partitioned with distilled water and ethyl acetate and decompressed. After distillation to obtain 30 g of ethyl acetate extract, hexane-ethyl acetate (8: 5) The tropical fruit extract mixture of the present invention was obtained from the fraction eluted in (Rf: 0.16, hexane-ethyl acetate = 8: 5).

Example 3 Preparation of Microcapsules

90 g of ethyl cellulose was dissolved in 400 g of methylene chloride, and 10 g of the tropical fruit extract mixture obtained in Example 2 was dispersed therein to prepare an oil phase. Next, 20 g of polyvinyl alcohol was dissolved in 980 g of water to prepare an aqueous phase. The oil phase prepared in the aqueous phase was added and emulsified for about 5 minutes at a rotational speed of 3000 rpm using a homomixer to prepare an O / W emulsion, and the emulsion was completely removed by methylene chloride using a vacuum distillation unit. After distillation under reduced pressure, the dispersion was filtered to recover only microcapsules, and the recovered microcapsules were dried in a dryer to obtain powdered microcapsules.

Example 4-8 Preparation of Cosmetics

According to the composition of the following Table 1 using the composition generally used in the art of the art to which the present invention belongs, the oily and aqueous components and surfactants were mixed with the microcapsules obtained in Example 3 and stirred with a homomixer, respectively. After heating and cooling to prepare Example 4-8 which is a uniformly mixed cosmetics.

Comparative Example 1 Extraction of Each Active Ingredient (Ethanol Extraction)

Each of the target materials of Example 1 was ground to a size of 0.3 cm or less by using a mill, and then extracts of the target materials by general ethanol extraction were used as comparative materials of the present invention.

Comparative Example 2: Preparation of Tropical Fruit Extract Mixture

Each extract of Comparative Example 1 was mixed at the same ratio to prepare a tropical fruit extract mixture.

Comparative Example 3: Preparation of Liposomes

Using the tropical fruit extract mixture obtained in Comparative Example 2 to prepare a liposome that can be generally prepared in the art according to the present invention.

Comparative Example 4-8: Preparation of Cosmetics

According to the composition of the following Table 1 using the composition generally used in the same industry in the art to which the present invention belongs, Comparative Examples 4 to 8 with the same composition as in Examples 4 to 8 except for using the liposome obtained in Comparative Example 3 A cosmetic of Comparative Example 8 was prepared.

TABLE 1

Raw material name Example 4 Example 5 Example 6 Example 7 Example 8 Comparative Example 4 Comparative Example 5 Comparative Example 6 Comparative Example 7 Comparative Example 8 Poly Solate-60 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.5 Sorbitan stearate 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Stearic acid 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Squalane 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Cerro stearyl alcohol 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Seryl Octanoate 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Carbomer 0.15 0.15 0.15 0.15 0.15 0.15 0.15 0.15 0.15 0.15 Triethanolamine 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 glycerin 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Example 3 Mixtures 0.1 Example 3 Mixtures One Example 3 Mixtures 5 Example 3 Mixtures 10 Example 3 Mixtures 20 Comparative Example 3 Mixture 0.1 Comparative Example 3 Mixture One Comparative Example 3 Mixture 5 Comparative Example 3 Mixture 10 Comparative Example 3 Mixture 20 antiseptic Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Purified water Total 100 Total 100 Total 100 Total 100 Total 100 Total 100 Total 100 Total 100 Total 100 Total 100

Experimental Example

Experimental Example 1 Comparative Experiment of Fibroblast Proliferation and Collagen Synthesis

The extract of Example 2 was used in Experimental Example 1. Human cell-derived fibroblasts were used to test their cell proliferation. Fibroblasts were used to proliferate cells stored in -70 ° C or liquid nitrogen. Fibroblasts cultured in T-75 flasks were washed 2-3 times with PBS, and the adherent cells were dropped using trypsin, and then cells were collected by centrifugation (Heraeus, Labofuge 400R) at 1500 rpm for 5 minutes. After centrifugation, the supernatant is discarded and 10 ml of DMEM (10% FBS) is added to the precipitated cells and mixed evenly. Measure the number of cells using a hemocytometer and divide 200 ⁴ ea / well of cells into each well of 96well. When the cells of about 50% of the well area were grown while incubating at 37 ° C. and 5% CO ₂ , the medium was exchanged with fresh DMEM (FBS10%). Cells were incubated at 37 ° C. and 5% CO ₂ for each time period.

MTT (3- (4,5-dimethylthiazol-2-yl) 2,5-diphenyl tetrazolium bromide, Sigma) was dissolved in PBS to 2 mg / ml and stored in the refrigerator. MTT reagent (5 mg) was used in each well. / Ml in PBS) 20ul each and incubated for another 2 hours, discard the supernatant and add 150μL of DMS (DMSO) and mix well or add 100μL of 0.04N-HCl and mix. After completion of all steps, measurements were made at 560 nm using an ELISA leader (μQuant, Bio-Tek instrument INC.) (Reference: 650 nm). The measurement results are shown in FIGS. 1 and 2.

Experimental Example 2 Experiment for Measuring Skin Elasticity Effect

Sixty healthy women (mean age 29.5 years old) over 20 years old were divided into six groups at a temperature of 22-24 ° C and a relative humidity of 55%, and the cosmetic compositions of Example 6 and Comparative Example 6 were applied for 12 weeks, mainly around the eyes. After (twice / day), skin elasticity was measured using a skin elasticity measuring instrument (Cutometer SEM 575, C + K Electronic Co., Germany). The test results are described in Table 2 below as ΔR5 values (R5 (12 weeks) -R5 (0 weeks)), which are average values for each test group of the Cutometer SEM 575. The closer it is, the better the elasticity is.

In addition, the degree of improvement was calculated by the following equation 1 and the calculation results are shown in Table 2.

[Equation 1]

[Table 2] Results of skin elasticity test (12 weeks)

Before application After application Skin elasticity enhancing effect (△ R5) % Improvement Example 6 0.74 1.16 0.42 56.76 Comparative Example 6 0.71 0.81 0.1 14.08

According to Table 2, when Example 6 containing the mixture of Example 3 was used, the skin elasticity increased by 42.68% compared to Comparative Example 6. Therefore, it can be seen that the cosmetic composition containing the microcapsules stabilized in Example 2 according to the present invention effectively enhances skin elasticity than when it is not stabilized by general extraction or microcapsules that do not maximize only active ingredients.

Experimental Example 3 Skin Moisture Measurement Experiment

Seventy healthy women (mean age 29.5 years) were divided into seven groups of 70 healthy women (22 ~ 24 ℃, 55% relative humidity, no air flow). The cosmetics of Example 6 and Comparative Example 6 were applied twice a day for 6 weeks to the entire face centered around the eyes in each group. By using Skicon-200 (IBS Co. Japan), the moisture content of the cheek area was measured before and after application to measure the persistence of the moisturizing effect. The results are shown in Table 3 as an average value for each test group.

Improvement was calculated according to the following equation.

[Equation 2]

TABLE 3

Before the test 6 weeks after application Improvement (%) Example 6 630 ± 10 890 ± 10 41.27 Comparative Example 6 630 ± 10 635 ± 10 0.78

According to Table 3, it can be seen that it is preferable to contain 0.1 to 20% by weight of the microcapsules stabilized in Example 2 in the cosmetic.

Experimental Example 4: human scalp experiment

In order to confirm that the cosmetic composition containing Example 3, which microencapsulates the active ingredient of tropical fruit, does not have skin irritation and other side effects, it is a patch on the human body of the cream formulations of Comparative Examples 7 and 7 and 8 above. A patch test was conducted.

The test consists of 30 healthy males and females who use a Finn chamber on the back to place cosmetics directly in aluminum discs or apply 40 μl of paper discs to the skin using scanpore tape. It fixed, the patch was removed after 24 hours, and the result was determined after 4 hours. Results are expressed numerically according to the severity and swelling severity, and the criteria for evaluation are based on the criteria of the International Contact Dermatitis Research Group (ICDRG) (Wooding et al, 1967; Rietschell, 1982; Fischer & Maibach, 1984; Aberer et al, 1993).

The criteria for evaluation are as follows.

0: no redness

1: erythema

2: redness and papules

3: redness, papules and vesicles

4: severe edema and vesicles

Based on the score determined according to the above criteria, the degree of stimulation was calculated according to Equation 3 below, and the results are shown in Table 4 below.

[Equation 3]

TABLE 4

Comparative Example 7 Example 7 Example 8 Irritation degree (%) 5.0 0.01 0.02

As can be seen from the results of Table 4, in Examples 7 and 8 there was no dermatitis or other irritation.

Experimental Example 5: Measurement of Transdermal Absorption by Size of Microcapsules

Particles having sizes of 50 μm, 80 μm, 120 μm, and 500 μm were prepared using PMMA polymers to which fluorescent substances were added by chemical bonding, respectively, and applied to the skin of female hairless guinea pigs, and then a predetermined time was elapsed. After cutting the cross section of the skin was measured for the fluorescence emitted from the percutaneously absorbed nanoparticles. Fluorescent PMMA polymer nanoparticles were prepared by covalently bonding fluorescent molecules to a carboxyl group of methacrylic acid of polymethylmethacrylate-co-methacrylic acid (molar ratio of methylmethacrylate and methacrylic acid is 84:16).

The manufacturing method will be described in detail as follows.

First, 34 g of polymethylmethacrylate-co-methacrylic acid was dissolved in 150 ml of anhydrous methylene chloride, and then 132 mg of dicyclohexylcarbodiimide and 74 mg of N-hydroxysuccinimide were added to activate the carboxyl group. After stirring for 1 hour, 222 mg of fluoresceamine was added to react the primary amine of the fluorescein amine with the activated carboxyl group to form an amide bond, thereby allowing the fluorescent molecules to be covalently bonded to the polymer chain. The reaction proceeded for 5 hours at room temperature and dark conditions. Dicyclohexyl urea, a by-product formed after the reaction, was removed through a 0.45 μm nylon filter and then precipitated in diethyl ether to remove the reaction reagents and unreacted residues. Subsequently, it was left in excess tertiary distilled water for one day to remove the remaining residues, and then dried using a vacuum oven at 40 degrees. As a result, PMMA particles having a size of 50 μm, 80 μm, 120 μm, and 500 μm to which fluorescent materials were added were prepared. Eight-week-old female hairless guinea pigs (strain IAF / HA-hrBR) were used for percutaneous absorption tests by size. The skin of the abdomen of the guinea pig was cut and mounted in a Franz-type diffusion cell (Lab Fine Instruments, Korea). A 50 mM phosphate buffer (pH 7.4, 0.1 M NaCl) was added to the receiving vessel (5 ml) of the plasma-type diffusion cell. The diffusion cell was mixed and dispersed at 600 rpm while maintaining 32 ° C, and 50 µl of a 10% (w / v) solution of fluorescent PMMA particles prepared for each size was placed in each donor container. . Absorption and diffusion were performed according to a predetermined time (average 12 hours), and the area of skin where absorption and diffusion occurred was 0.64 cm ² . After the absorption and diffusion of the particles, the non-absorbed particles remaining on the skin were washed with dried Kimwipes or ethanol 10ml, and the cross-section of the skin was cut to measure the distribution of the fluorescent PMMA particles absorbed on the skin section.

Intra-dermal distribution measurement results of the particles are shown in Table 5, and the photographs are shown in FIGS. 3 and 4.

TABLE 5

Average size of particles Percutaneous absorption area 50 μm 35 μm 80㎛ 17 μm 120 μm 12㎛ 500 ㎛ 7㎛

In Table 5, it can be seen that the percutaneous absorption of the particles largely depends on the average particle diameter. Particles with an average diameter of 50 μm pass through the epidermis and are absorbed and diffused to the top of the dermis layer. If the particle size exceeds 500 μm, the particles remain on the skin surface and are no longer absorbed into the skin. Did not happen. Particles with an average diameter of about 50 μm diffuse into the intercellular lipids of the skin, and the hydrophobicity of the polymer is considered to have an effect of promoting transdermal absorption.

Therefore, when the active ingredient is poorly or unstable in the active ingredient is trapped in the particles of about 50㎛ average particle diameter, it was found that the percutaneous absorption of the active ingredient is possible through delivery to the skin through the particles.

Experimental Example 6: Stability Experiment

The stability of the formulation for the cosmetics containing the stabilized microcapsules according to the present invention was measured by the following method.

Example 6, Comparative Examples 6 and 7 were placed in an opaque glass container in a constant temperature bath maintained at 45 ℃ constant sample stored for 12 weeks, in an opaque glass jar in a fully shaded refrigerator maintained at 4 ℃ constant For samples stored for 12 weeks and samples stored for 12 weeks in a circulation chamber (once / day) circulating at -5 ° C to 37 ° C, separation, degree of discoloration and precipitation were measured. The separation and discoloration degree of the product was classified into the following six grades and the evaluation results are shown in Table 6 below.

Product discoloration evaluation criteria

0: No change 1: Very little separation (discoloration)

2: Slightly separated (discolored) 3: Slightly separated (discolored)

4: Extremely separated (discolored) 5: Extremely separated (discolored)

[Table 6] Isolation and Discoloration of Test Substances

Temperature Example 6 Comparative Example 6 Comparative Example 7 45 ℃ 0 3 3 4 ℃ 0 2 2 cycle 0 2 3

As can be seen in Table 6, Example 6 stabilized through microcapsules was stable without discoloration or separation symptoms in 4 ℃, 45 ℃ and circulation test, Comparative Examples 6 and 7 used directly in the formulation without stabilization In case of separation (discoloration) occurred it was found that unstable.

In addition, the results obtained by classifying the degree of precipitation of the product into the following six grades are shown in Table 7 below.

Product Sedimentation Evaluation Criteria

0: no change 1: very slight precipitation

2: little precipitate 3: little precipitation

4: settling heavily 5: settling extremely severe

[Table 7] Precipitation Degree of Test Substance

Temperature Example 6 Comparative Example 6 Comparative Example 7 45 ℃ 0 3 3 4 ℃ 0 3 2 cycle 0 3 2

As can be seen in Table 7, the cosmetics stabilized with the microcapsules according to the present invention do not occur precipitation, it can be seen that the stabilization.

As such, when the extract of the tropical fruit is added without stabilization, precipitation and discoloration occur easily by reacting with other weak ionic polymers in the formulation.

However, when the extract is stabilized with microcapsules and applied to the formulation as in the present invention, it can be seen that the precipitation and discoloration reaction are minimized even when added in excess.

As described above, according to the functional cosmetic composition for wrinkle improvement according to the present invention by microencapsulating the active ingredient fraction extract of tropical fruit to improve its stability to improve the wrinkles of the skin can maintain the effect in a stable state for a long time There is such an effect.

In addition, according to the functional cosmetic composition for improving wrinkles according to the present invention is added without stabilizing the extract of tropical fruit, precipitates and discoloration is easily reacted with other weak ionic polymers in the formulation, but the extract as in the present invention When stabilized with microcapsules and applied to the formulation, there is an effect of minimizing precipitation and discoloration even when added in excess.

Claims (6)

Wrinkle improvement functional cosmetic composition, characterized in that it comprises a microcapsules stabilized tropical fruit extract. The method of claim 1, The tropical fruit extract contains Gac, Noni, CamuCamu, Acai, Goji, Guanara, Sea Buckthron and Maca extracts. Wrinkle improvement functional cosmetic composition, characterized in that. The method of claim 1, The microcapsules, characterized in that containing 0.1 to 20% by weight based on the total weight of the cosmetic composition, functional cosmetic composition for wrinkle improvement. The method of claim 1, The size of the microcapsules, characterized in that less than 50㎛, wrinkles functional cosmetic composition for improvement. The method according to any one of claims 1 to 4, (A) dissolving a water-insoluble cellulose derivative in an organic solvent, and adding the tropical fruit extract to prepare an oil phase; (b) dissolving at least 12 hydrophile lipophil balance (HLB) water-soluble surfactants in water to prepare an aqueous phase; (c) emulsifying while adding an oil phase to the water phase to prepare an oil in water (O / W) emulsion; And (d) a functional cosmetic composition for improving wrinkles, characterized in that the capsule is prepared through the step of drying the emulsion. The method of claim 5, The water-insoluble cellulose derivative is a water-insoluble cellulose derivative selected from the group consisting of ethyl cellulose, cellulose acetate, cellulose acetate butyrate and cellulose acetate propionate, The water-soluble surfactant is a functional cosmetics for improving wrinkles, characterized in that the water-soluble surfactant selected from the group consisting of polyoxyethylene nonionic surfactant, polyhydric alcohol ester nonionic surfactant, polymeric surfactant. Composition.

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