KR20070059187A - 이중 가닥 리보핵산에 의한 염증성 질환의 치료 방법 - Google Patents

이중 가닥 리보핵산에 의한 염증성 질환의 치료 방법 Download PDF

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KR20070059187A
KR20070059187A KR1020077009492A KR20077009492A KR20070059187A KR 20070059187 A KR20070059187 A KR 20070059187A KR 1020077009492 A KR1020077009492 A KR 1020077009492A KR 20077009492 A KR20077009492 A KR 20077009492A KR 20070059187 A KR20070059187 A KR 20070059187A
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seq
sirna
seqidno
cells
tnf
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Korean (ko)
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쿤유안 쿠이
리샨 챈
유칭 챈
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나스텍 파마수티컬 컴퍼니 인코포레이티드
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
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    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
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    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications
    • C12N2320/32—Special delivery means, e.g. tissue-specific

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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KR1020077009492A 2004-09-27 2005-09-27 이중 가닥 리보핵산에 의한 염증성 질환의 치료 방법 Withdrawn KR20070059187A (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US61341604P 2004-09-27 2004-09-27
US60/613,416 2004-09-27
US65657205P 2005-02-25 2005-02-25
US60/656,572 2005-02-25
US66783305P 2005-04-01 2005-04-01
US60/667,833 2005-04-01
US11/121,566 2005-05-04
US11/121,566 US20060040882A1 (en) 2004-05-04 2005-05-04 Compostions and methods for enhancing delivery of nucleic acids into cells and for modifying expression of target genes in cells

Publications (1)

Publication Number Publication Date
KR20070059187A true KR20070059187A (ko) 2007-06-11

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KR1020077009492A Withdrawn KR20070059187A (ko) 2004-09-27 2005-09-27 이중 가닥 리보핵산에 의한 염증성 질환의 치료 방법

Country Status (9)

Country Link
US (3) US20060040882A1 (https=)
EP (1) EP1793864A4 (https=)
JP (1) JP2008514647A (https=)
KR (1) KR20070059187A (https=)
AU (1) AU2005290336A1 (https=)
CA (1) CA2580996A1 (https=)
NO (1) NO20072148L (https=)
NZ (1) NZ553828A (https=)
WO (1) WO2006037126A2 (https=)

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US8299236B2 (en) 2012-10-30
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US20060040882A1 (en) 2006-02-23
WO2006037126A3 (en) 2007-12-06
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