KR20040036723A - 치료 효과를 갖는 신규 이미다조피리딘 화합물 - Google Patents

치료 효과를 갖는 신규 이미다조피리딘 화합물 Download PDF

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Publication number
KR20040036723A
KR20040036723A KR10-2004-7002466A KR20047002466A KR20040036723A KR 20040036723 A KR20040036723 A KR 20040036723A KR 20047002466 A KR20047002466 A KR 20047002466A KR 20040036723 A KR20040036723 A KR 20040036723A
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KR
South Korea
Prior art keywords
alkyl
formula
compound
hydroxylated
het
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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KR10-2004-7002466A
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English (en)
Korean (ko)
Inventor
코스라트 아민
미카엘 다흘스트룀
페터 노르트베르크
인게마 스타르케
Original Assignee
아스트라제네카 아베
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Publication date
Application filed by 아스트라제네카 아베 filed Critical 아스트라제네카 아베
Publication of KR20040036723A publication Critical patent/KR20040036723A/ko
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR10-2004-7002466A 2001-08-22 2002-08-21 치료 효과를 갖는 신규 이미다조피리딘 화합물 Ceased KR20040036723A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0102808A SE0102808D0 (sv) 2001-08-22 2001-08-22 New compounds
SE0102808-3 2001-08-22
PCT/SE2002/001489 WO2003018582A1 (en) 2001-08-22 2002-08-21 Novel imidazopyridine compounds with therapeutic effect

Publications (1)

Publication Number Publication Date
KR20040036723A true KR20040036723A (ko) 2004-04-30

Family

ID=20285105

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2004-7002466A Ceased KR20040036723A (ko) 2001-08-22 2002-08-21 치료 효과를 갖는 신규 이미다조피리딘 화합물

Country Status (19)

Country Link
US (1) US20040220209A1 (enExample)
EP (1) EP1421083A1 (enExample)
JP (1) JP2005501870A (enExample)
KR (1) KR20040036723A (enExample)
CN (1) CN100343252C (enExample)
AR (1) AR035465A1 (enExample)
BR (1) BR0211846A (enExample)
CA (1) CA2456350A1 (enExample)
HU (1) HUP0401350A3 (enExample)
IL (1) IL160143A0 (enExample)
IS (1) IS7159A (enExample)
MX (1) MXPA04001402A (enExample)
NO (1) NO20040760L (enExample)
NZ (1) NZ531110A (enExample)
PL (1) PL367971A1 (enExample)
RU (1) RU2294935C2 (enExample)
SE (1) SE0102808D0 (enExample)
WO (1) WO2003018582A1 (enExample)
ZA (1) ZA200401114B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR200449743Y1 (ko) * 2008-03-11 2010-08-05 주식회사 보루네오가구 파티션용 상부 스크린의 고정구조

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0301904D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
EP1682133A1 (en) 2003-11-03 2006-07-26 AstraZeneca AB Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux
US20080033006A1 (en) * 2004-01-26 2008-02-07 Altana Pharma Ag 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors
EA011512B1 (ru) * 2004-12-17 2009-04-28 Ракуалиа Фарма Инк. Производные хромана, полезные в качестве антагонистов кислотной помпы
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
WO2007107827A1 (en) * 2006-03-17 2007-09-27 Raqualia Pharma Inc. Chromane derivatives
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
FI20086158A0 (fi) 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
EP2452680B1 (en) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
MX2012003469A (es) * 2009-09-24 2012-04-19 Hoffmann La Roche Derivados de imidazopiridina o imidazopirimidina como inhibidores fosfodiesterasa 10a.
FR2962437B1 (fr) 2010-07-06 2012-08-17 Sanofi Aventis Derives d'imidazopyridine, leur procede de preparation et leur application en therapeutique
KR102120513B1 (ko) * 2013-01-31 2020-06-08 네오메드 인스티튜트 이미다조피리딘 화합물 및 이의 용도
CN105164126B (zh) * 2013-04-30 2017-05-31 豪夫迈·罗氏有限公司 吡唑酰胺的Pd‑催化偶联
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
DK3880678T3 (da) 2018-11-13 2025-06-10 Glaxosmithkline Intellectual Property No 3 Ltd Krystallinske former af p2x3-modulator methyl(s)-2-((2-(2,6-difluoro-4-(methylcarbamoyl )phenyl)-7-methylimidazo[1,2-a]pyridin-3-yl)methyl)morpholin-4-carboxylat
CA3131312A1 (en) 2019-02-25 2020-09-03 Bellus Health Cough Inc. Treatment with p2x3 modulators

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (en) * 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
UA48122C2 (uk) * 1993-10-11 2002-08-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх АЛКОКСІАЛКІЛКАРБАМАТИ ІМІДАЗО[1,2-а]ПІРИДИНІВ, СПОСІБ ЇХ ОДЕРЖАННЯ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
CN1046726C (zh) * 1994-07-28 1999-11-24 比克·古尔顿·劳姆贝尔格化学公司 咪唑并吡啶－吡咯烷酮、其制法和药用
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR200449743Y1 (ko) * 2008-03-11 2010-08-05 주식회사 보루네오가구 파티션용 상부 스크린의 고정구조

Also Published As

Publication number Publication date
CA2456350A1 (en) 2003-03-06
RU2004103628A (ru) 2005-06-27
US20040220209A1 (en) 2004-11-04
ZA200401114B (en) 2005-06-22
RU2294935C2 (ru) 2007-03-10
PL367971A1 (en) 2005-03-07
HUP0401350A3 (en) 2009-03-02
WO2003018582A1 (en) 2003-03-06
CN100343252C (zh) 2007-10-17
JP2005501870A (ja) 2005-01-20
HUP0401350A2 (hu) 2004-12-28
BR0211846A (pt) 2004-09-08
IS7159A (is) 2004-02-20
NO20040760L (no) 2004-02-20
IL160143A0 (en) 2004-06-20
MXPA04001402A (es) 2004-05-27
CN1543464A (zh) 2004-11-03
NZ531110A (en) 2005-10-28
AR035465A1 (es) 2004-05-26
SE0102808D0 (sv) 2001-08-22
EP1421083A1 (en) 2004-05-26

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