KR20030047873A - 클라리트로마이신 및 클라리트로마이신 중간체의 제조방법, 실질적으로는 옥심이 제거된 클라리트로마이신 및이를 포함하는 약학적 조성물 - Google Patents

클라리트로마이신 및 클라리트로마이신 중간체의 제조방법, 실질적으로는 옥심이 제거된 클라리트로마이신 및이를 포함하는 약학적 조성물 Download PDF

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Publication number
KR20030047873A
KR20030047873A KR1020027011330A KR20027011330A KR20030047873A KR 20030047873 A KR20030047873 A KR 20030047873A KR 1020027011330 A KR1020027011330 A KR 1020027011330A KR 20027011330 A KR20027011330 A KR 20027011330A KR 20030047873 A KR20030047873 A KR 20030047873A
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KR
South Korea
Prior art keywords
clarithromycin
oxime
protective
silylated
erythromycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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KR1020027011330A
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English (en)
Korean (ko)
Inventor
아브루토브일리야
리프쉬쯔이골
르위너엘리자베쓰
Original Assignee
테바 파마슈티컬 인더스트리즈 리미티드
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Publication of KR20030047873A publication Critical patent/KR20030047873A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020027011330A 2000-02-29 2000-12-15 클라리트로마이신 및 클라리트로마이신 중간체의 제조방법, 실질적으로는 옥심이 제거된 클라리트로마이신 및이를 포함하는 약학적 조성물 Ceased KR20030047873A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US18588800P 2000-02-29 2000-02-29
US60/185,888 2000-02-29
US18912000P 2000-03-14 2000-03-14
US60/189,120 2000-03-14
US21323900P 2000-06-22 2000-06-22
US60/213,239 2000-06-22

Publications (1)

Publication Number Publication Date
KR20030047873A true KR20030047873A (ko) 2003-06-18

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KR1020027011330A Ceased KR20030047873A (ko) 2000-02-29 2000-12-15 클라리트로마이신 및 클라리트로마이신 중간체의 제조방법, 실질적으로는 옥심이 제거된 클라리트로마이신 및이를 포함하는 약학적 조성물

Country Status (15)

Country Link
US (3) US6617436B2 (enExample)
EP (1) EP1313486A1 (enExample)
JP (1) JP2004509062A (enExample)
KR (1) KR20030047873A (enExample)
AU (2) AU2001225787C1 (enExample)
CA (1) CA2401571A1 (enExample)
CZ (1) CZ20023167A3 (enExample)
HR (1) HRP20020709A2 (enExample)
HU (1) HUP0302466A2 (enExample)
IL (1) IL151496A0 (enExample)
IS (1) IS6531A (enExample)
PL (1) PL366021A1 (enExample)
SK (1) SK13722002A3 (enExample)
WO (1) WO2001064224A1 (enExample)
YU (1) YU64202A (enExample)

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CN102718821B (zh) * 2012-06-27 2014-12-03 浙江国邦药业有限公司 一种克拉霉素合成过程中甲基化反应以及甲基化试剂的回收套用方法
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CN106905204B (zh) * 2017-02-24 2018-07-20 杭州新桂实业有限公司 一种克拉霉素合成过程中甲基化反应溶剂的回收套用方法
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Also Published As

Publication number Publication date
SK13722002A3 (sk) 2003-08-05
US6617436B2 (en) 2003-09-09
US20030216556A1 (en) 2003-11-20
US20010037015A1 (en) 2001-11-01
HRP20020709A2 (en) 2004-12-31
YU64202A (sh) 2005-03-15
CZ20023167A3 (cs) 2003-10-15
JP2004509062A (ja) 2004-03-25
US20060205683A1 (en) 2006-09-14
IS6531A (is) 2002-08-28
PL366021A1 (en) 2005-01-24
AU2001225787B2 (en) 2005-12-08
HUP0302466A2 (hu) 2003-11-28
CA2401571A1 (en) 2001-09-07
US7101858B2 (en) 2006-09-05
AU2001225787C1 (en) 2006-09-21
IL151496A0 (en) 2003-04-10
AU2578701A (en) 2001-09-12
EP1313486A1 (en) 2003-05-28
WO2001064224A1 (en) 2001-09-07

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