KR20030037446A - Skin care cosmetics containing Prunus mume extracts - Google Patents

Abstract

PURPOSE: Provided is a cosmetic composition for skin care, containing a Mume Fructus extract which activates keratinocyte as a skin cell, promotes keratinization and keeps skin moist. Therefore, the composition is safe to the skin and has excellent skin care effect. CONSTITUTION: The skin cosmetic composition contains 0.01 to 10% by weight of a Mume Fructus extract, based on the total weight of the composition. The Mume Fructus extract is obtained by extracting Mume Fructus, followed by filtration, aging at 0 to 10deg.C for 3 to 10 days and refiltration. The cosmetic composition is formulated into a form selected from a lotion, cream, massage cream, essence or a mask pack. For an example, 1.0% by weight of the Mume Fructus extract is mixed with 4.5% by weight of 1,3-butylene glycol, 5.0% by weight of glycerine, 10.0% by weight of ethanol, 0.1% by weight of oleyl alcohol, 0.5% by weight of Polysorbate 20, 0.1% by weight of propyl paraben, 0.3% by weight of pf.kn-753 and the balance of purified water.

Description

Skin cosmetic composition containing plum extract {Skin care cosmetics containing Prunus mume extracts}

The present invention relates to a cosmetic composition containing a plum extract.

Skin is the largest organ in the human body that protects our body from external stimuli. Its barrier function, temperature control function, excretion function and respiration prevent the outflow of moisture and useful components from outside the skin. It plays various physiological roles such as function. The skin is composed of epidermis, dermis and subcutaneous fat layer. The epidermis, the outermost layer of skin, protects the skin from the external environment.

The epidermal layer is largely divided into basal layer, granule layer, transparent layer, and stratum corneum. Keratinocytes disappear from the basal layer to the stratum corneum, which is the outermost layer of the skin, every 28 days.

Cells constituting the epidermal layer include various cells such as keratinocytes, Langelhans cells, and Merkel cells, and most of them are keratinocytes. Keratinosite is a cell proliferation activity in the basal layer and through the granule layer to synthesize the cell components, including keratin, and finally reach the stratum corneum. However, if the problem occurs in the activity of keratinocytes, skin aging, wrinkle generation, and skin dryness occur, resulting in sagging skin, resulting in decreased elasticity of the skin. Therefore, in order to keep skin healthy, lustrous and beautiful, it is necessary to activate keratinocytes constituting the epidermal layer of the skin and improve the function of the stratum corneum.

A typical substance that accelerates the keratinization process of keratinocytes is alpha hydroxy acid (AHA). AHA is a substance that is widely used as a keratin accelerator, but when a large amount is applied to the skin, it not only causes skin irritation but also has a problem of adversely affecting stabilization of the formulation even in the formulation of the cosmetic composition including the same.

Accordingly, the present inventors are able to maintain healthy skin by promoting the exfoliation of citric acid and various fruit acids (apple, tartaric acid, succinic acid) contained in the plum extract to promote the exfoliation of the skin, and also allergic to the skin with natural ingredients The present invention has been completed by focusing on the fact that it causes little side effects such as reactions.

Therefore, an object of the present invention is to provide a safe and effective skin cosmetic composition by activating keratinocytes skin cells using the extract of plum to promote exfoliation of the skin and to maintain skin moisturizing.

The present invention relates to a skin cosmetic composition containing Prunus mume extract.

Plum extract used in the present invention is contained in 0.01 to 10% by weight, preferably 0.01 to 5% by weight relative to the total weight of the cosmetic. If it is less than 0.01% by weight, it is difficult to obtain a substantial effect of exfoliation and moisturizing. If it is more than 10% by weight, it will adversely affect product stability.

Plum is a rose family, and its fruit has long been widely used for food and medicinal purposes. Plum is a weak alkaline food and contains a large amount of beneficial nutrients such as citric acid, minerals and various minerals. Citric acid is a kind of α-hydroxy acid (AHA) and is known as an effective ingredient for removing dry skin and the stratum corneum.

The extract of the plum is filtered by filtration of the fruit juice obtained by ripening aged at 0 ~ 10 ℃ for 3 to 10 days, and then filtered again using the stock solution. Moreover, what concentrates this stock solution again can also be used.

Plum extract in the present invention can be prepared as a conventional basic cosmetics, for example, softening longevity (skin), nutritious longevity (milk lotion), nutrition cream, massage cream, essence, pack, etc. to remove the exfoliation and moisturizing cosmetics. .

Hereinafter, the content of the present invention will be described in detail with reference to Examples and Experimental Examples, but the present invention is not limited thereto.

Example 1 Preparation of Plum Extract

In the present invention, in order to maintain as much of the fruit acid component in the extract of plum plum was used in the medium. The fruit juice obtained by crushing 1 kg of fresh medium with a mixer was filtered through Whatman filter paper, aged for 7 days at low temperature, and filtered again to obtain 0.5 kg of the stock solution.

Experimental Example 1: exfoliation effect of the plum extract-containing cosmetics

Ten healthy women and men (between 20 and 30 years old) continue to apply cosmetics containing 1% dihydroxyacetone to the upper arm. Dihydroxyacetone artificially makes the surface of the skin brown. After one week, after confirming that the skin became brown, the upper arm was divided into three places, and the product according to the prescription example 2, the product without the plum extract and the control were determined and applied twice a day. Subsequently, while applying, the L value (L-value) of skin brightness was measured at weekly intervals, and the experiment was performed for 28 days. The results are shown in Table 1 below.

Exfoliation effect of products containing plum extract Control Product by prescription example 2 Exfoliation effect (%) 34.5 67.5

As shown in Table 1, the formulation containing the plum extract showed a result of removing the pigmentation by dihydroxyacetone more than twice as compared to the control group, from which the plum extract has an excellent effect on exfoliation Could confirm.

Experimental Example 2: Cell proliferation effect of Apricot extract

Skin keratinocytes were inoculated in DMEM medium containing 4.5 g / L glucose, 10% serum, and 1% antibiotics and cultured at 37 ° C. in a 50 ml T-flask. After 24 hours of incubation under 5% CO ₂ conditions, cells were isolated by treatment with 0.05% Trypsin containing 0.02% EDTA, inoculated in 50 ml T-flask and incubated for 48 hours and again 1 × 10 Incubated in 96 wells to ⁴ / well (well) and incubated for 12 hours. After incubation, each well was added with 10, 20, 50, 100, 200, and 500 µg / ml plum extract. After the addition of the plum extract 24 hours, 48 hours, 72 hours, the activity of each cell at the concentration measured by MTT method is shown in Table 2 below.

Cell Activity Effect of Plum Extract Concentration of Apricot Extract (µg / mL) Cell activity effect (absorbance at 570 nm) 0 hours 24 hours 48 hours 72 hours Control 0.115 0.125 0.135 0.140 10 0.114 0.126 0.136 0.140 20 0.112 0.136 0.165 0.175 50 0.113 0.145 0.179 0.193 100 0.105 0.163 0.189 0.201 200 0.109 0.113 0.148 0.159 500 0.116 0.105 0.065 0.058

As shown in Table 2 above, the extract of plum was superior to the control activity than the control group, especially in the concentration range of 10 ~ 100 ㎍ / ㎖ could be confirmed that the increase in proportion to the concentration.

Experimental Example 3: Skin Moisturizing Effect of Plum Extract Containing Products

Thirty healthy women and men (between 20 and 30 years old) were measured for their moisturizing effect. First, the skin moisture content before using the product for 30 people was measured by using a coronocytometer, and the product according to Formulation Example 2 was applied to the skin for 4 weeks. While applying the product, the moisture content of the skin was measured by averaging the value of ΔV measured using a coniocimeter at a weekly interval.

Moisturizing Effect of Plum Extract Control Product by prescription example 2 Skin moisturizing effect (%) 25.7 76.5

As shown in Table 3, the cosmetic composition containing a plum extract was confirmed that the skin moisturizing effect is excellent.

Through the above experimental examples, it was confirmed that the plum extract is excellent in the exfoliation, activation of keratinocytes, moisturizing the skin, and because the natural cosmetics have no skin side effects.

Prescription Example 1 : Prescription Example of Softening Soap (Skin) in Cosmetics Containing Plum Extract

ingredient Content (unit: weight%) Plum Extract 1.0 1,3-butylene glycol 4.5 glycerin 5.0 ethanol 10.0 Oleyl alcohol 0.1 Poly Solvent 20 0.5 Propylparaben 0.1 pf.kn-753 0.3 Purified water Remaining amount system 100

Prescription Example 2 : Prescription example of nutrient cosmetic lotion (lotion) in cosmetics containing plum extract

ingredient Content (unit: weight%) Plum Extract 1.0 1,3-butylene glycol 4.5 glycerin 5.0 Triethanolamine 5.0 Liquid paraffin 5.0 Squalane 3.0 Macadamia Nut Oil 2.0 Polysorbate 60 1.0 Solbitan Sesquioleate 1.0 Carboxy Vinyl Polymer 1.0 Propylparaben 0.03 pf.kn-563 0.09 Purified water Remaining amount system 100

Formulation Example 3 Formulation Example of Nutritional Cream in Cosmetics Containing Plum Extract

ingredient Content (unit: weight%) Plum Extract 1.0 Propylene glycol 4.5 glycerin 5.0 Triethanolamine 5.0 Liquid paraffin 5.0 Squalane 3.0 vaseline 8.0 Beeswax 1.0 Polysorbate 60 1.0 Solbitan Sesquioleate 1.0 Carboxy Vinyl Polymer 0.5 Propylparaben 0.1 pf.kn-953 0.05 Purified water Remaining amount system 100

Plum extract according to the present invention provides a safe and effective skin cosmetic composition by activating the skin cells keratinocytes, promoting exfoliation of the skin and maintaining skin moisturizing.

Claims (4)

Skin cosmetic containing plum extract. The skin cosmetic according to claim 1, wherein the extract of plum is contained in an amount of 0.01 to 10% by weight based on the total weight of the cosmetic. The skin cosmetic according to claim 1, wherein the plum extract is a stock solution which is filtered again after filtration of the fruit juice obtained by squeezing the fresh medium and aging at 0 to 10 ° C for 3 to 10 days. The skin cosmetic according to claim 1, which has a formulation selected from a flexible lotion, a nourishing lotion, a nourishing cream, a massage cream, an essence or a pack.