KR20020093364A - Additive compositions including laminaria saccharina extract for cosmetics and cosmetics containing the same - Google Patents

Abstract

PURPOSE: A cosmetic containing a cosmetic additive composition containing an extract of Laminaria Saccharina, phytosphingosine and Portulaca oleracea L. is provided which exhibits excellent skin elasticity, reduces the size of pores in mammalian skin and inhibits proliferation against bacteria present in skin. CONSTITUTION: The cosmetic composition for improving skin trouble contains 1 to 20% by weight of Laminaria Saccharina, 0.01 to 1.0% by weight of phytosphingosine, 1 to 15% by weight of Portulaca oleracea L. and additionally 1 to 45% by weight of at least one selected from the group consisting of cinnamon extract, ginger extract and Sanguisorba officinalis L. extract.

Description

Cosmetic additive composition containing seaweed extract and cosmetics including the same {{ITITIVE COMPOSITIONS INCLUDING LAMINARIA SACCHARINA EXTRACT FOR COSMETICS AND COSMETICS CONTAINING THE SAME}

The present invention relates to a cosmetic additive composition containing a seaweed (Laminaria Saccharina) extract and a cosmetic comprising the same, and more particularly, to a cosmetic containing a cosmetic additive composition comprising a seaweed extract, phytosphingosine, March extract It has excellent skin elasticity and pore reduction effect and proliferation inhibitory effect on skin regrowth bacteria.

Pores are two ways of connecting the inside and outside of the skin. That is, there is a passage through which sebum is discharged out and a glands passage, a hole through which sweat is secreted. The passage through which the hairs come out and the sebaceous gland are connected together and the passage through which secreted sebum is discharged to the outside are generally called pores, which are divided into three according to the shape of the hair follicle and sebaceous glands. Lose. The first is a downy sac, very small sebaceous gland, small thin hairs appearing on the body surface, and the sebum secretion amount is small, so there is little skin trouble in the pores. Second is sebaceous follicle pore (sebaceous follicle pore) is a lot of sebaceous secretion, the space between the hair and the passage is large, and thus the pores that form the path causing various skin problems and acne. Finally, terminal beard follicle (terminal beard follicle) is a passage mainly existing in the head portion of the pores because the pores close to the pores because the skin is hardly occurs.

The sebaceous glands present in the skin are evenly distributed throughout the body surface and are generally distributed at about 100 / cm2. However, the face, forehead, etc. are present much more 400 ~ 900 / ㎠ and only a few are present in the palm, soles, hands and the like. In general, the number of pores throughout our body is not constant, but about 5 million are known.

The pores are the passages of sebum, and their expansion factors are closely related to the development and activity of sebaceous glands and the smoothness of sebum discharge. In general, pores dilate with deterioration of the elasticity of the skin due to ultraviolet rays, dry conditions, stress, aging and the like. In addition, as the child enters puberty after adolescence, the secretion of male hormones (androgen) increases due to natural physiological phenomena, the secretion of sebum becomes more active in sebaceous glands. As a result, the amount of sebum secreted through the pores increases, so that the pores which are the secretory passages of sebum naturally expand. At this time, sebum is not discharged smoothly, clogged pores or proliferation of harmful bacteria caused by contaminants is the main cause of acne, which is a symbol of puberty.

Therefore, it is not possible to fundamentally eliminate the cause of enlargement of pores caused by human physiological phenomena, but for healthy pore management, the area around the pores is cleaned to prevent the clogging of pores, and the keratinization of the pores is prevented so that the sebum may be smoothed to the outside. It is essential for healthy pore management to prevent the enlargement of pores by increasing the skin elasticity by promoting the release, preventing the penetration of harmful bacteria in the pores and inhibiting their proliferation, promoting skin moisturizing and collagen synthesis.

Therefore, the first object of the present invention is to provide a useful cosmetic additive composition effective in improving and supplementing such skin troubles.

A second object of the present invention is to provide a cosmetic which is effective in improving and supplementing skin troubles, which contains a cosmetic additive composition according to the first object of the present invention in a specific ratio.

According to a preferred embodiment of the present invention for achieving the first object of the present invention, seaweed Laminaria Saccharina extract 1-20% by weight, Phytosphingosine 0.01-1.0% by weight, Machi Prefecture extract There is provided a cosmetic additive composition comprising 1 to 15% by weight.

According to another preferred aspect of the present invention for achieving the first object of the present invention, a cinnamon extract, ginger extract, cucumber extract or any mixture thereof as an optional ingredient in the cosmetic additive composition according to the first object described above 1 A cosmetic additive composition is provided which contains ˜45 wt% and the content of each of the above components does not exceed 15 wt%.

According to a preferred aspect of the present invention for achieving the second object of the present invention, the cosmetic additive composition according to the first and second objects described above 0.01 to 5.0% by weight, preferably 0.1 to 4.0 based on the total weight of the cosmetic A cosmetic comprising a weight% is provided.

As seaweed that can be applied to the present invention, Laminaria Saccharina, which is known to inhibit 5α-reductase activity, is preferable, and sebum secretion is suppressed by adding 1 to 20% by weight of the cosmetic additive composition of the present invention. And shrink pores. Laminaria saccharina is also called Sugar Kelp, a type of brown algae.

The laminaria saccharina extract in the present invention can be obtained by immersion in a conventional extraction solvent commonly used in the art, or by heating and refluxing, followed by filtration and concentration. Specifically, the outpost is immersed in a solvent alone or appropriately mixed with organic solvents such as alcohols such as methanol, ethanol, isopropanol, propylene glycol, 1,3-butylene glycol, glycerin, hydrous acetone, and acetic acid ethyl ester. To extract. The use ratio of raw material: solvent is generally in a ratio of 1: 0.5 to 3.0 by weight, preferably 1: 1, but this is not limiting in the present invention.

Phytosphingosine has an antimicrobial effect and prevents the pores from being enlarged by stimulating the wall of pores due to sebum decomposition of dermal fungus.

Machi Prefecture (the main ingredient is 3,3 ', 4-trimethylellagic acid) is a plant of the genus Portulaca, called purslane or pentaflora, which has antibacterial effect. After washing the porthole, the solvent described above is added and extracted in the same ratio as described above to obtain a light brown transparent extract.

Referring to the optional ingredients in the present invention, cucumber grass is known to have a hemostatic and astringent action in herbal medicine, cinnamon (the main ingredient is known as cinnamaldehyde) is known to have a convergent and bacterial growth inhibitory effect, ginger (The main ingredient is biabolene) is an Indian native plant, which has an antiseptic effect and a biotoxicity removal effect, and is particularly known to be excellent in bactericidal effect. These extracts can be obtained by the same conditions and methods as those described above.

The above-described skin trouble improvement and supplement cosmetic additive composition of the present invention is contained in the cosmetics in an amount of 0.01 to 5.0% by weight, preferably 0.1 to 4.0% by weight based on the total weight of the cosmetic, such a skin trouble improvement and supplement cosmetics Examples thereof include lotions, creams, essences, or packs.

Hereinafter, the present invention will be described in more detail with reference to Examples.

(Example)

Example 1: Preparation of Cosmetic Additive Composition 1

A cosmetic additive composition was prepared with the following composition:

Laminaria Saccharina Extract 3.0%

Phytosphingosine 0.1%

Machi Prefecture Extract 10.0%

Purified water level

The extracts of Laminaria saccharina and Machi prefecture were washed with the outpost, immersed in equal weight ethanol, and left standing for 2 weeks and filtered.

Example 2 Preparation of Cosmetic Additive Composition 2

A cosmetic additive composition was prepared with the following composition:

Laminaria Saccharina Extract 3.0%

Phytosphingosine 0.1%

Machi Prefecture Extract 10.0%

Cinnamon and Cucumber Extract Each 1.0%

Ginger Extract 0.5%

Purified water level

Laminaria saccharina, machi, cinnamon, cucumber and ginger extracts were washed, and then immersed in equal weight 1,3-butylene glycol, and left standing for 2 weeks and filtered.

Example 3 Preparation of Cream Cosmetics

A cream cosmetic was prepared as follows.

Raw material name Comparative Example 1 Example 3 Example 4 Example 5 A. Methyl Glucose Dioleate 1.5 1.5 1.5 1.5 PEG 20 Methyl Glucosesesquistearate 3.0 3.0 3.0 3.0 Petrolatum 8.0 8.0 8.0 8.0 Isopropyl Palmitate 3.0 3.0 3.0 3.0 Mineral oil 6.0 6.0 6.0 6.0 Dimethicone 0.5 0.5 0.5 0.5 Stearyl alcohol 2.0 2.0 2.0 2.0 Cetyl alcohol 1.0 1.0 1.0 1.0 B. Deionized Water Remaining amount Remaining amount Remaining amount Remaining amount Magnesium aluminum silicate 1.0 1.0 1.0 1.0 Xanthan Gum 0.3 0.3 0.3 0.3 C. Preservatives q.s. q.s. q.s. q.s. Cinnamon, Ginger and Cucumber Extract, respectively 2.0 - - - D. Additive Composition of Example 1 - - - 3.0 Additive Composition of Example 2 - 2.0 4.0 -

Example 4 Preparation of Essence Cosmetic

Essence cosmetics were prepared as shown below.

Raw material name Comparative Example 2 Example 6 Example 7 A. Liquid Paraffin 1.5 1.5 1.5 Biswax 3.0 3.0 3.0 Stearyl alcohol 8.0 8.0 8.0 Polyoxyethylene (10) Glyceryl Triisostearate 3.0 3.0 3.0 Polyoxyethylene (15) Cetyl Ether 6.0 6.0 6.0 Na-PCA 2.0 2.0 2.0 B. Deionized Water Remaining amount Remaining amount Remaining amount Preservative q.s. q.s. q.s. C. Additive Composition of Example 2 - 2.0 0.05 Seaweed extract 2.0 - -

Test Example 1 Pore Size Measurement

ㅇ Subjects: A double-blind test was conducted on the faces of 15 women in their 20s with healthy skin, no history and oily skin.

○ Test method: Both sides of the face were divided into two parts, one side containing a cream containing the additive composition of Example or Comparative Example, the other side a placebo cream for control, and the measurement site was limited to the cheek. The period of use was 8 weeks in total, and the change in skin elasticity was observed using Cutometer SEM 474 (Couraga and Khazaka, GmbH, Cologne, Germany) before and after 4 weeks and 8 weeks of product use. Pore reduction effect was measured by using a skin image analyzer (Skin Image Analyser) before the use of the product, 15 minutes after application of the pore diameter.

ㅇ Result

The pore reduction effect was evaluated by measuring pore size by Video-microscopy 15 minutes after application:

Change in pore diameter (% increase and decrease) Comparative Example 1 Example 3 Example 4 Example 5 3% -30% -21% -12%

Change in pore size Comparative Example 1 Comparative Example 2 Example 6 Example 7 Pore size change 3% 3% -6% -One%

Comparing Examples 3 and 5 with Comparative Example 1, the use of only cinnamon, ginger, and cucumber extract was found to be ineffective, but in the case of Examples 3 and 5 in combination with seaweed extract, phytosphingosine, and machi A clear pore reduction effect was obtained, and in the case of Example 3, which further added cinnamon, ginger, and cucumber extract, a more remarkable effect was obtained.

When only the seaweed extract of Comparative Example 2 was used alone, as in Comparative Example 1 using only cinnamon, ginger and cucumber extracts, it was difficult to expect a reduction in pore size, but the combination of seaweed extract, phytosphingosine, and machi In the case of Examples 6 and 7, remarkable results were obtained.

In addition, in the case of Example 4 using the additive composition of Example 2, it was confirmed that the decrease in the pore diameter is smaller than in the case of Example 3 using 2%. These results can be confirmed that when the additive composition of Examples 1 and 2 is used in excess, skin irritation is induced and the effect is rather halved.

In Example 7, when the additive composition of Example 2 was used at 0.05%, it was confirmed that the effect was weak.

Test Example 2: Measurement of pore size and skin elasticity

ㅇ Subjects: A double-blind test was conducted on the faces of 15 women in their 20s who had healthy skin, no history and oily skin.

ㅇ Test method: Both sides of the face were divided into two parts, one on which the cream containing the additive composition of Example or Comparative Example was applied, and the other, a control placebo cream, and the measurement area was limited to the cheeks. The period of use was 8 weeks in total, and the change in skin elasticity was observed using Cutometer SEM 474 (Couraga and Khazaka, GmbH, Cologne, Germany) before and after 4 weeks and 8 weeks of product use.

ㅇ Result

Comparative Example 1 Example 3 4 weeks later 13% 36% 8 weeks later 13% 47%

Test Example 3 Determination of the effect of inhibiting the growth of pore flora

In order to measure the effect of inhibiting the growth of pore flora, the number of viable bacteria of Staphylococcus aureus , Staphylococcus epidermidis , and Propionibacterium acnes were measured before and after application.

Except that the content of the additive composition of Example 2 was set to 1% by weight and 3% by weight, except that the same essence cosmetic composition (Examples 8 and 9, respectively) and the seaweed extract were not included. Prepare the same cosmetics as in Example 2 (Comparative Example 3) and apply to the face, then rub the face with a cotton pad three times over time, immerse the cotton in distilled water, dilute after shaking and inoculate in a medium to inoculate antibacterial activity Measured. The units in Tables 6-8 are log cfu / ml.

(1) Staphylococcus aureus

-36 ° C aerobic conditions on Tryptic Soy Agar medium

Hours (hr) 0 6 12 18 24 30 36 Comparative Example 3 6.8 7.1 7.6 8.7 9.5 98. 9.9 Example 8 6.8 6.5 6.1 5.0 3.1 2.0 0.8 Example 9 6.8 6.4 6.0 4.6 2.5 1.5 0.7

(2) S.epidermidis

-36 ° C aerobic conditions on Tryptic Soy Agar medium

Hours (hr) 0 6 12 18 24 30 36 Comparative Example 3 7.3 7.1 7.2 8.3 8.7 9.0 9.0 Example 8 7.3 5.6 4.8 2.9 2.0 1.1 0.7 Example 9 7.3 5.7 4.8 2.9 2.0 1.1 0.7

(3) Propionibacterium acnes

30 ° C. anaerobic conditions on Brain Heart Mixed Agar Medium

Hours (hr) 0 12 24 36 48 60 72 Comparative Example 3 5.9 6.0 6.0 8.3 8.7 9.0 9.7 Example 8 5.9 5.8 5.7 5.0 3.1 2.0 0.7 Example 9 5.9 5.7 5.6 4.6 2.5 1.9 0.7

From the above test results, it was found that the essence cosmetics containing 1 wt% and 3 wt% of the additive composition of Example 2 exhibited excellent antibacterial effect.

Test Example 4: Long-term storage stability

Long-term storage stability for Examples 3 to 7 and Comparative Examples 1 and 2 were evaluated in a thermostat (-5 ° C, 37 ° C, 43 ° C, 50 ° C cycle) and at room temperature and the results are shown in Table 9. The cycle evaluation was carried out according to the circulating temperature method in which a cycle was gradually circulated at a cycle of -5 ° C. → 25 ° C. → 45 ° C. at a cycle of 24 hours, and the emulsified state was destroyed and separated. Evaluation scores were expressed as very stable: ◎, normal: ㅇ, instability: △, separation: X.

Item Example Comparative example 3 4 5 6 7 One 2 -5 ℃ 1 month ◎ ◎ ◎ ◎ ◎ ◎ ◎ 3 months ◎ ◎ ◎ ◎ ◎ ◎ ◎ 6 months ◎ ◎ ◎ ◎ ◎ ◎ ◎ 37 ℃ 1 month ◎ ◎ ◎ ◎ ◎ ◎ ◎ 3 months ◎ ◎ ◎ ◎ ◎ ◎ ◎ 6 months ◎ ◎ ◎ ◎ ◎ O ◎ 43 ℃ 1 month ◎ ◎ ◎ ◎ ◎ ◎ ◎ 3 months ◎ ◎ ◎ ◎ ◎ O ◎ 6 months ◎ ◎ ◎ ◎ ◎ O ◎ 50 ℃ 1 month ◎ ◎ ◎ ◎ ◎ ◎ ㅇ 2 months ◎ ◎ ◎ ◎ ◎ ㅇ ◎ cycle 10th ◎ ◎ ◎ ◎ ◎ ㅇ ◎ 20 times ◎ ◎ ◎ ◎ ◎ ㅇ ㅇ Room temperature 1 month ◎ ◎ ◎ ◎ ◎ ◎ ◎ 3 months ◎ ◎ ◎ ◎ ◎ ◎ ◎ 6 months ◎ ◎ ◎ ◎ ◎ ◎ ◎ 12 months ◎ ◎ ◎ ◎ ◎ ㅇ ◎

As a result of the above long-term storage stability test, the embodiments of the present invention were found to have excellent long-term storage stability.

Test Example 5: Skin safety (irritant)

For 30 healthy men and women, an appropriate amount (2.0 g) of each sample was buried in the hazel chamber for patch test for 48 hours, and the hazel chamber was removed. This was first judged, removed, and read again after 48 hours to make this a second judgment, and the results are shown in Table 10 below.

division 1st judgment 2nd judgment score － ± + ++ - ± + ++ Example 3 28 2 0 0 29 One 0 0 0.56 Example 4 29 One 0 0 30 0 0 0 0.00 Example 5 30 0 0 0 30 0 0 0 0.00 Example 6 29 One 0 0 30 0 0 0 0.00 Example 7 30 0 0 0 30 0 0 0 0.56 Comparative Example 1 27 3 0 0 28 2 0 0 1.38 Comparative Example 2 29 One 0 0 29 One 0 0 0.83

* Judgment table

－: No reaction (irritation degree: 0)

± suspected positive reaction. Slight erythema reaction (irritation degree: 0.5)

+: Slight positive reaction; Erythema, papules, positive pullback reactions (irritation degree: 1.0)

++: Severe positive reaction. Vesicular reactions: erythema, papules, infiltrating lesions, vesicles (irritation degree: 2.0)

+++: Severe positive reaction (Irritation degree: 3.0)

[Calculation 1]

(± responders x 0.5) + (+ responders x 1) + (++ responders x 2) + (+++ responders x 3)

* Stimulus = ---------------------------------------------- ----------- x100x1 / 2 Number of Subjects x Maximum Response (3)

As in the skin irritation test results, the embodiments of the present invention were found to have very low irritation.

As described above, the cosmetic additive of the present invention has a 50% improvement in skin elasticity in a cream containing 2%, and a test result for the growth inhibitory effect on S.aurus, S.epidermidis, and P.acnes In all bacterial strains, almost all of them died within 36 to 72 hours, and the pores reduction effect test showed about 30% improvement.

Therefore, the cosmetic additive composition according to the present invention imparts to the cosmetics an excellent effect effective in reducing pores and improving skin without affecting long-term storage stability and skin irritation when added to conventional cosmetics.

Claims (4)

Cosmetic additive composition for improving and supplementing skin problems, including 1-20% by weight of seaweed Laminaria Saccharina extract, 0.01-1.0% by weight Phytosphingosine, 1-15% by weight extract The method according to claim 1, wherein the additive composition further comprises 1 to 45% by weight of at least one extract selected from the group consisting of cinnamon extract, ginger extract and cucumber extract, wherein the cinnamon extract, ginger extract and cucumber extract Each content does not exceed 15% by weight of the cosmetic additive composition for improving and supplementing skin problems. A skin trouble improvement and supplement cosmetic composition comprising 0.01 to 5.0% by weight of the cosmetic additive composition for skin trouble improvement and supplement according to claim 1 or 2, based on the total weight of the cosmetic. According to claim 3, wherein the cosmetic additive composition comprises 0.1 to 4.0% by weight, wherein the cosmetic is any one selected from the group consisting of lotions, creams, essences and packs for improving and supplementing skin problems cosmetics.