KR102419399B1 - Cica-care cream composition and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a cosmetic composition and, more specifically, to a cosmetic cream composition that has significantly improved efficacy in terms of skin regeneration and wound healing by containing components derived from Centella asiatica species as active ingredients, and is helpful for strengthening the skin barrier, wherein the components derived from Centella asiatica species are highly effective in regenerating damaged skin.

Description

CICA-CARE CREAM COMPOSITION AND MANUFACTURING METHOD THEREOF

The present invention relates to a cosmetic composition, and more particularly, a cosmetic cream that helps to strengthen the skin barrier by remarkably improving the efficacy of skin regeneration and wound healing by containing cica ingredients, which have excellent regenerating effects of damaged skin, as an active ingredient. to the composition.

The most important role of the skin is to act as a defense barrier that protects the skin from external bacterial invasion and damage, and to prevent heat and moisture loss from the inside.

The skin is composed of several layers, the outermost of which is called the epidermis. What is known to show regenerative ability in the epidermis are keratinocyte stem cells of the skin present in the basal layer. The skin tissue consists of the epidermis, dermis, and hypodermis. The epidermis receives direct and frequent damage from the outside, and its recovery is very important. The epidermis consists of a layer of keratinocytes. The keratinocytes in the skin synthesize keratin during differentiation and differentiate to form a layer and move toward the epidermis.

The innermost cell layer of the epidermis is called the basal layer, and the cells that make up this layer are called basal cells. As the cells of the basal layer go through proliferation and division and differentiate into the stratum corneum, the epidermal cells seek internal reinforcement through cross-linking of keratin, and are also connected with desmosomes tightly connected to other cells in the same layer with keratin to form the entire layer. keep the structure In addition, as epidermal cells differentiate into the outer epidermis, they produce and secrete lipids to form a double-layered tissue in the plasma membrane cornified with proteins to protect the skin surface from external harmful environments.

Integumentary cells, which are the outermost parts of the skin, are constantly peeled off and removed, and other cells growing under them continue to take their place. Therefore, when external skin damage occurs, wound healing occurs immediately. Wounds in which the epidermis is lost while exposed to the basement membrane due to damage to the epidermis and dermis are bright red on the wound surface.

Recently, laser treatment, dermabrasion, etc. are popular for the purpose of cosmetic or disease treatment. Laser therapy is to treat single-wavelength light by using the characteristics of radiation, transmission, absorption, and energy transfer of light. In the sense of a single wavelength, there are inevitably many types of treatment lasers according to wavelength bands and energy emission methods. In other words, the treatment laser is different for each disease. When the laser beam hits the body, it is converted into heat, and the temperature of the area absorbed by the heat rises, and protein denaturation begins when it exceeds 40 degrees.

On the other hand, dermabrasion is a procedure to induce the production of new epidermis and stimulate the production of collagen fibers in the dermis by peeling off a part of the skin to various degrees depending on the type of dermabrasion using chemicals or lasers. It is used to treat acne, scars, wrinkles, pigmented lesions, and enlarged pores.

After such laser treatment or dermabrasion, it is important to induce skin regeneration without an inflammatory reaction.

On the other hand, in recent years, the skin is stimulated and sensitive due to environmental factors such as fine dust and ultraviolet rays and various causes occurring in the living environment, such as stress, automobile smoke, wrong eating habits and contaminated food, or it loses its ability to regenerate and recover. There is a growing problem of serious damage caused by discarding.

To this end, various cosmetics for skin regeneration or wound healing are being developed.

However, most of the cosmetics for skin regeneration and wound healing developed so far contain a large amount of artificially manufactured compound ingredients, so side effects of irritating the skin appear or there is a limitation in skin regeneration ability.

Republic of Korea Patent Registration No. 10-2253894

The present invention is to solve the above problems, and by containing cica components, which have excellent regenerating effects of damaged skin, as an active ingredient, the efficacy of skin regeneration and wound healing is remarkably improved, and a cosmetic cream composition that helps to strengthen the skin barrier would like to provide

These and other objects and advantages of the present invention will become apparent from the following description of preferred embodiments.

The above object, Centella asiatica extract (Centella asiatica extract), asiaticoside (Asiaticoside), madecassic acid (Madecassic acid) and a cica component comprising a mixture of asiatic acid (Asiatic acid) as an active ingredient, It can be achieved by a cica care cream composition for skin regeneration.

Based on the total weight of the composition, the Centella asiatica extract is included in an amount of 0.001 to 0.100 weight %, and the asiaticoside is included in an amount of 0.0001 to 0.001 weight %, and the Madecassic acid is included in an amount of 0.0001 to 0.001 weight %. acid) is included in an amount of 0.0001 to 0.001% by weight, and the Asian acid is included in an amount of 0.0001 to 0.001% by weight.

The composition is glycerin, mineral oil, isohexadecane, petrolatum, dimethicone, caprylyl glycol, allatoin, Ethylhexylglycerin, adenosine, butylene glycol, dipotassium glycyrrhizate, panthenol, and one selected from the group consisting of beta glucan It is characterized in that it further comprises a mixture of the above.

The composition, cetearyl alcohol as an emulsion stabilizer, cetearyl Olivate and sorbitan Olivate as a surfactant, stearic acid as an emulsifying agent (Stearic acid), Carbomer as a thickener, Triethanolamine as a pH adjuster, Phenoxyethanol and Chlorphenesin as preservatives, Disodium EDTA as a chelating agent, and It is characterized in that it contains 1,2-hexanediol as a solvent.

According to the present invention, it is possible to provide a cosmetic cream composition that helps to strengthen the skin barrier by remarkably improving the efficacy of skin regeneration and wound healing by containing cica components excellent in the regeneration effect of damaged skin as an active ingredient.

In addition, the composition of the present invention contains physiologically active ingredients and functional ingredients that help anti-inflammation, trouble alleviation, moisturizing, skin soothing, etc. in a specific mixing ratio, thereby increasing the skin's natural recovery power even for troubled or sensitive skin. let it be

However, the effects of the present invention are not limited to the above-mentioned effects, and other effects not mentioned will be clearly understood by those skilled in the art from the following description.

Hereinafter, the present invention will be described in detail with reference to embodiments and drawings of the present invention. It will be apparent to those of ordinary skill in the art that these examples are merely presented by way of example to explain the present invention in more detail, and that the scope of the present invention is not limited by these examples. .

Further, unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, and in case of conflict, this specification, including definitions will take precedence.

In order to clearly explain the invention proposed in the drawings, parts irrelevant to the description are omitted, and similar reference numerals are assigned to similar parts throughout the specification. And, when a part "includes" a certain component, this means that other components may be further included, rather than excluding other components, unless otherwise stated. In addition, "unit" described in the specification means one unit or block that performs a specific function.

In each step, identification numbers (first, second, etc.) are used for convenience of description, and identification numbers do not describe the order of each step, and each step does not clearly describe a specific order in context. It may be performed differently from the order specified above. That is, each step may be performed in the same order as the specified order, may be performed substantially simultaneously, or may be performed in the reverse order.

In the present invention, in this specification, the term "CiCa" used in "Cica ingredient" and/or "CiCa Care" is a word derived from the French 'Cicatrice (wound)'. , may mean the effect of regenerating damaged skin.

"Cica care cream" according to an embodiment of the present invention may be a cosmetic composition, specifically a cream composition, that heals damaged and wounded skin and helps to restore the skin barrier.

However, the formulation of the cosmetic composition including all the ingredients of the present invention may not be limited to "cream", and if necessary, a solution, external ointment, foam, nutrient lotion, softening lotion, pack, softening water, emulsion, may C-up base, essence, soap, liquid detergent, bath agent, sunscreen cream, sun oil, suspension, emulsion, paste, gel, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, It can be prepared in a formulation selected from the group consisting of a wax foundation, a patch, and a spray.

Hereinafter, embodiments and examples of the present application will be described in detail. However, it may not be limited to these embodiments and examples herein.

One aspect of the present application, Centella asiatica extract (Centella asiatica extract), asiaticoside (Asiaticoside), madecassic acid (Madecassic acid) and asiatic acid (Asiatic acid) comprising a cica component as an active ingredient, Provided is a cica care cream composition for skin regeneration.

The cica care cream composition has a use for skin regeneration. The "skin regeneration" refers to a process of restoring skin tissue from damage caused by external and internal causes of the skin. The damage caused by the external cause may include ultraviolet rays, external pollutants, wounds, trauma, and the like, and the damage caused by the internal cause may include stress.

The cica care cream composition may further include ingredients such as a skin conditioning agent, an emulsion stabilizer, a thickener, and a chelating agent, if necessary, and other additives commonly used in the art to form a cream formulation. can do.

Hereinafter, a detailed look at the composition of the cica care cream composition is as follows.

cica ingredient

The cica care cream composition according to an embodiment of the present invention includes a cica component.

The cica component may include a mixture of the Centella asiatica extract, the asiaticoside, the madecassic acid, and the asiatic acid.

The asiaticoside, the madecassic acid, and the asiatic acid may be a component obtained by separating from the Centella asiatica extract.

The cica component, based on the total weight of the composition, may be included in less than 1% by weight, for example, 0.0001 to 0.900% by weight, specifically, 0.0001 to 0.10% by weight, more specifically, 0.0001 to 0.050% by weight.

As an example, with respect to the total amount of the composition, the Centella asiatica extract is included in, for example, 0.001 to 0.100% by weight, for example, 0.030% by weight, and the asiaticoside is, for example, For example, 0.0001 to 0.001% by weight, for example, it is included in 0.0004% by weight, and the madecassic acid is, for example, 0.0001 to 0.001% by weight, for example, 0.0003% by weight. Acid (Asiatic acid) may be included, for example, in an amount of 0.0001 to 0.001% by weight, for example, 0.0003% by weight. By including the cica component having the above-described composition ratio, it is possible to significantly increase the skin regeneration effect.

skin conditioning agent

The cica care cream composition according to an embodiment of the present invention includes a skin conditioning agent of one or more various component combinations.

The skin conditioning agent exhibits effects such as moisturizing, soothing, whitening, antioxidant, elasticity enhancement, wrinkle improvement and prevention, wound relief, inflammation relief, redness relief, etc. not significantly limited.

The skin conditioning agent, for example, glycerin (Glycerin), mineral oil (Mineral oil), isohexadecane (Isohexadecane), petrolatum (Petrolatum), dimethicone (Dimethicone), caprylyl glycol (Caprylyl glycol), allatoin (Allatoin), ethylhexylglycerin (Ethylhexylglycerin), adenosine (Adenosine), butylene glycol (Butylene Glycol), dipotassium glycyrrhizate (Dipotassium glycyrrhizate), from the group consisting of panthenol (Panthenol) and beta glucan (Beta glucan) It may include one or more selected mixtures.

As an example, the skin conditioning agent is glycerin, mineral oil, isohexadecane, petrolatum, dimethicone, caprylyl glycol, alla A mixture of Allatoin, Ethylhexylglycerin, Adenosine, Butylene Glycol, Dipotassium glycyrrhizate, Panthenol and Beta glucan may include

As an example, based on the total weight of the composition, the glycerin (Glycerin) is, for example, 12.00 to 17.00% by weight, for example, 15.020% by weight, the mineral oil (Mineral oil) is, for example, 1.00 to 5.00 It is included in weight %, for example, 3% by weight, and the isohexadecane is, for example, 0.50 to 4.00% by weight, for example, 2% by weight, and the petrolatum is, for example For example, 0.50 to 4.00% by weight, for example, included in 2% by weight, the dimethicone (Dimethicone) is, for example, 0.01 to 2% by weight, for example, included in 0.5% by weight, the caprylyl glycol (Caprylyl glycol) is included in, for example, 0.01 to 2 wt%, for example, 0.2 wt%, and the Allatoin is, for example, 0.01 to 0.10 wt%, for example, 0.05 wt% And, the ethylhexylglycerin (Ethylhexylglycerin) is, for example, 0.01 to 0.10% by weight, for example, is included in 0.05% by weight, the adenosine (Adenosine) is, for example, 0.01 to 0.10% by weight, for example, 0.04 Included in wt%, the butylene glycol (Butylene Glycol) is, for example, 0.005 to 0.050 wt%, for example, is included in 0.010 wt%, the dipotassium glycyrrhizate (Dipotassium glycyrrhizate) is, for example , 0.005 to 0.050% by weight, for example, is included in 0.010% by weight, and the panthenol is, for example, 0.005 to 0.050% by weight, for example, 0.010% by weight, the beta glucan (Beta glucan) is, for example, 0.0001 to 0.001% by weight, for example, may be included in 0.0004% by weight.

The skin conditioning agent is an oil-soluble physiologically active ingredient, idebenone, tocopherol and its derivatives (eg, tocopheryl acetate), coenzyme Q10, vitamin C derivatives, oleanolic acid, ursolic acid, diacetyl Boldin (diacetyl boldine), oil-soluble licorice and 0006 may further include one or more selected from the group consisting of retinol (retinol) and its derivatives. For example, the oil-soluble physiologically active ingredient may be idebenone and tocopheryl acetate.

The skin conditioning agent is a water-soluble physiologically active ingredient, hydroquinone derivatives such as arbutin, water-soluble vitamin C derivatives including ascorbic acid-2-glucoside (AA2G), niacinamide, N-acetyl glucose It may further include one or more selected from the group consisting of various water-soluble extracts such as amine (N-acetylglucosamine) and Sangbaekpi extract. For example, the water-soluble physiologically active ingredient may be arbutin and niacinamide.

The physiologically active ingredient may be included within the usual content range used in the relevant field, if necessary. For example, it may be included in an amount of 0.0001 to 0.1% by weight, for example, 0.0005 to 0.001% by weight, based on the total weight of the composition.

The skin conditioning agent may further include a functional ingredient. The functional ingredient may include at least one selected from the group consisting of fermented garlic extract, calamine, sprout oat extract, turmeric extract, sandalwood oil and natural liquid ingredients.

More specifically, the functional ingredient, including the fermented garlic extract, may impart antioxidant and anti-inflammatory effects to the skin. The fermented garlic extract may be a hot water extract of garlic fermented with lactic acid bacteria, and may be prepared using a conventional lactic acid bacteria fermentation method.

The functional ingredient may include calamine. The calamine is a mixture of zinc oxide and ferric oxide (iron oxide), and it helps to relieve troubles and soothe the skin by anti-inflammatory, antiseptic, and antibacterial effects.

The functional ingredients include sprout oat extract to secure anti-inflammatory, antibacterial, and moisturizing effects, and exhibit excellent efficacy in alleviating redness.

The functional ingredients include turmeric extract, that is, curcumin, and help relieve inflammation, antioxidant, and skin regeneration.

The functional ingredient includes sandalwood oil. The sandalwood is used as an essential oil containing 100% only natural sandalwood that grows wild in Hawaii.

The functional component may include a mixture of sunflower oil, almond oil, virginia perennial bark/leaf/twig extract, cucumber fruit extract, arnica montana flower extract and mallow extract, which are natural liquid ingredients.

Each material of the functional component may be included in an amount of 0.0001 to 0.1% by weight, for example, 0.0002 to 0.0007% by weight, independently of each other, based on the total weight of the composition.

skin penetration enhancer

The cica care cream composition according to an embodiment of the present invention may include a skin penetration enhancer. The skin penetration enhancer may increase the fluidity of the skin lipid film and stabilize the cica component and the components of the skin conditioning agent to increase their skin penetration rate.

The skin penetration enhancer includes lysophospholipids and dihydrochalcone-based compounds.

The lysophospholipid has a cone-shaped structure to increase skin film compatibility, thereby increasing the skin delivery rate of physiologically active substances. The lysophospholipids may be used without particular limitation as long as they are commonly used in cosmetic compositions. For example, soybean-derived lysophospholipids, soybean-derived hydrogenated lysophospholipids, egg yolk-derived lysophospholipids, egg yolk-derived hydrogenated lysophospholipids, etc. may be used, and these may be used alone or in combination of two or more.

For example, the lysophospholipid may be a mixture of lysophosphatidylcholine, lysophosphatidylethanolamine, lysophosphatidylglycerol and lysophosphatidylserine.

The dihydrochalcone-based compound is, for example, phloretin, 3',5'-dihydroxy-2',4',6'-trimethoxy dihydrochalcone pediceline (3',5') -Dihydroxy-2′,4′,6′-trimethoxy dihydrochalcone pedicellin), methyllinderone, asparathin, and the like. For example, the dihydrochalcone-based compound may be floretin. In addition to its role as a skin penetration enhancer, phloretin also exerts effects such as antioxidant and skin tone improvement.

Each component of the skin penetration enhancer may be included in an amount of 0.0001 to 0.1% by weight, for example, 0.0002 to 0.0007% by weight, independently of each other, based on the total weight of the composition.

additive

The cica care cream composition according to an embodiment of the present invention is, for example, a surfactant, an emulsifier, a solvent, purified water, a chelating agent, a thickener, a pH adjuster, a stabilizer, a preservative, a fragrance, a solubilizer, a thickening agent, a gelling agent, It may contain one or more additives selected from the group consisting of emollients, antioxidants, suspending agents, foaming agents, fragrances, fillers, sequestering agents, vitamins, blocking agents, wetting agents, essential oils, dyes and pigments.

As an example, the additive is, as an emulsion stabilizer, Cetearyl alcohol, as a surfactant, Cetearyl Olivate and Sorbitan Olivate, an emulsifying agent. Stearic acid as a thickener, Carbomer as a thickener, Triethanolamine as a pH adjuster, Phenoxyethanol and Chlorphenesin as a preservative, Disodium as a chelating agent EDTA) and 1,2-hexanediol as the solvent.

As an example, relative to the total weight of the composition, the cetearyl alcohol (Cetearyl alcohol) is, for example, 2.00 to 7.00% by weight, for example, is included in 4.5% by weight, the cetearyl olivate (Cetearyl Olivate) For example, 0.50 to 3.00% by weight, for example, 1.2% by weight, the sorbitan olivate (Sorbitan Olivate) is included, for example, 0.01 to 3.00% by weight, for example, 0.80% by weight, The stearic acid is, for example, included in 0.1 to 3.00 wt%, for example, 0.50 wt%, and the carbomer is, for example, 0.1 to 3.00 wt%, for example, 0.40 wt%, The triethanolamine (Triethanolamine) is, for example, contained in 0.1 to 3.00 wt%, for example, 0.40 wt%, the phenoxyethanol (Phenoxyethanol) is, for example, 0.1 to 3.00 wt%, for example, 0.30 wt% %, and the clofenesin is, for example, 0.1 to 3.00% by weight, for example, 0.20% by weight, and the disodium EDTA is, for example, 0.1 to 3.00 It may be included in an amount of weight %, for example, 0.30 weight%, and the 1,2-hexanediol (1,2-hexanediol) may be included in an amount of, for example, 0.001 to 0.01 weight%, for example, 0.004 weight%.

As an example, the additive is a fragrance or fragrance component, linalool, hexyl cinnamal, limonene, citronellol, butylphenyl methylpropional (Butylphenyl Methylpropional), benzyl Salicylate (Benzyl salicylate) and geraniol (Geraniol) may be included.

As an example, relative to the total weight of the composition, the linalool (Linalool) is, for example, 0.001 to 0.1% by weight, for example, 0.01488% by weight, the hexyl namal (Hexyl cinnamal) is, for example, 0.001 to 0.1% by weight, for example, 0.01386% by weight, the limonene is included, for example, 0.001 to 0.1% by weight, for example, 0.01061% by weight, the citronellol is included, for example For example, it is included in 0.0001 to 0.01% by weight, for example, 0.006486% by weight, and the butylphenyl methylpropional (Butylphenyl Methylpropional) is, for example, 0.0001 to 0.01% by weight, for example, it is included in 0.00562% by weight, The benzyl salicylate is included in, for example, 0.0001 to 0.01 wt%, for example, 0.003018 wt%, and the geraniol is, for example, 0.0001 to 0.01 wt%, for example , may be included in 0.002954 wt%.

As an example, the additive may include a fragrance component such as lavender, rose, rosemary, peppermint, sandalwood and citrus. The type of the perfume ingredient is not limited thereto, and any perfume ingredient for a cosmetic composition that is commonly used may be used.

The perfume component may be included in an amount of, for example, 0.01 to 1% by weight, for example, 0.142572% by weight, based on the total weight of the composition.

The composition may include the aforementioned cica component, and further include at least one component selected from a skin conditioning agent, a skin penetration enhancer, and an additive, and may include purified water in the remaining amount. The purified water may be mixed with deep sea water, and in this case, the mixing ratio of the purified water and deep sea water is 1: 0.2 to 0.4 by weight, for example, it is preferable to have a weight ratio of 1: 0.25.

The composition contains cica components, which are excellent in regenerating damaged skin, as an active ingredient, and thus the efficacy of skin regeneration and wound healing is remarkably improved, thereby helping to strengthen the skin barrier.

In addition, the composition contains physiologically active ingredients and functional ingredients that help anti-inflammatory, trouble relief, moisturizing, skin soothing, etc. in a specific mixing ratio, so that the skin's natural recovery power can be increased even for troubled or sensitive skin. .

Hereinafter, the configuration of the present invention and its effects will be described in more detail through specific examples and comparative examples. However, these examples are for explaining the present invention in more detail, and the scope of the present invention is not limited to these examples.

[Examples 1 to 10]

A cica care cream composition was prepared by mixing the ingredients and contents shown in Tables 1 and 2 below. The unit of each content is % by weight.

[Experimental Example 1: Evaluation of skin improvement effect]

For the cica cream prepared according to the respective compositions of Examples 1 to 10, the degree of improvement in skin regeneration and wound healing, as well as skin moisturizing, trouble relief, and overall preference were evaluated. For a more accurate comparison, commercially available cosmetics for skin regeneration were compared together as Comparative Examples. (Comparative Example 1: Cicaplast Balm B5 manufactured by Company L, Comparative Example 2: Derma Repair Cica Cream manufactured by Company A, Comparative Example 3: Genuine Pantensoside 5 Cica Balm manufactured by Company E)

After 50 subjects who received laser treatment or dermabrasion treatment, each of the cica cream of Examples 1 to 10 and Comparative Examples 1 to 3 was used for 5 people for a week (twice a day (morning and evening)), After evaluation with a 10-point scale (1: very bad --> 10: very good), significance was tested with Duncan's multiple range test. The results are shown in Tables 3 and 4 below.

As shown in Tables 3 and 4, the cica cream prepared according to the compositions of Examples 1 to 10 of the present invention has overall skin regeneration and wound healing effects compared to commercially available cosmetics for skin regeneration (Comparative Examples 1 to 3). It was found to be excellent, and the overall preference for trouble relieving and skin moisturizing was higher. Among them, Example 10 received the most excellent evaluation for all items.

In this specification, only a few examples among the various embodiments performed by the present inventors are described, but the technical spirit of the present invention is not limited or limited thereto, and it is of course that it may be modified and variously implemented by those skilled in the art.

Claims (4)

Based on the total weight of the composition, 0.001 to 0.100% by weight of Centella asiatica extract, 0.0001 to 0.001% by weight of Asiaticoside, 0.0001 to 0.001% by weight of Madecassic acid and asiatica acid (Asiatic acid) 0.0001 to 0.001% by weight of cica component as an active ingredient,
The composition, glycerin (Glycerin) 12.00 to 17.00% by weight, mineral oil (Mineral oil) 1.00 to 5.00% by weight, isohexadecane (Isohexadecane) 0.50 to 4.00% by weight, petrolatum (Petrolatum) 0.50 to 4.00% by weight, dime Dimethicone 0.01 to 2 wt%, Caprylyl glycol 0.01 to 2 wt%, Allatoin 0.01 to 0.10 wt%, Ethylhexylglycerin 0.01 to 0.10 wt%, Adenosine ) 0.01 to 0.10 wt%, Butylene Glycol 0.005 to 0.050 wt%, Dipotassium glycyrrhizate 0.005 to 0.050 wt%, Panthenol 0.005 to 0.050 wt%, and Beta glucan) further comprising a skin conditioning agent comprising a mixture of 0.0001 to 0.001% by weight,
The skin conditioning agent further comprises idebenone, tocopheryl acetate, arbutin and niacinamide, wherein the idebenone, tocopheryl acetate, arbutin and niacinamide are each independently, 0.0001 to 0.1 wt% based on the total weight of the composition included in the content of
The skin conditioning agent, fermented garlic extract; calamine; sprout oat extract; turmeric extract; sandalwood oil; And, sunflower oil, almond oil, Virginia chrysanthemum bark/leaf/twig extract, cucumber fruit extract, arnica montana flower extract, and a natural liquid component that is a mixture of mallow extract further comprising a functional ingredient comprising a mixture of the functional ingredient Each material is included, independently of each other, in an amount of 0.0001 to 0.1% by weight based on the total weight of the composition,
The composition, Cetearyl alcohol (Cetearyl alcohol) 2.00 to 7.00 wt%, Cetearyl Olivate (Cetearyl Olivate) 0.50 to 3.00 wt%, Sorbitan Olivate (Sorbitan Olivate) 0.01 to 3.00 wt%, Stearic acid 0.1 to 3.00 wt%, Carbomer (Carbomer) 0.1 to 3.00 wt%, Triethanolamine (Triethanolamine) 0.1 to 3.00 wt%, Phenoxyethanol (Phenoxyethanol) 0.1 to 3.00 wt%, Clofenesin (Chlorphenesin) 0.1 to 3.00 wt% , Disodium EDTA (Disodium EDTA) 0.1 to 3.00% by weight and 1,2-hexanediol (1,2-hexanediol) further comprising an additive comprising a mixture of 0.001 to 0.01% by weight,
The composition contains purified water as the remaining amount, but the purified water is a cica care cream composition for skin regeneration, characterized in that it is used by mixing purified water and deep sea water in a weight ratio of 1: 0.2 to 0.4. delete delete delete