FR2921561A1 - COSMETIC COMPOSITION FOR IMPROVING SKIN CONDITION - Google Patents
COSMETIC COMPOSITION FOR IMPROVING SKIN CONDITION Download PDFInfo
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- FR2921561A1 FR2921561A1 FR0758001A FR0758001A FR2921561A1 FR 2921561 A1 FR2921561 A1 FR 2921561A1 FR 0758001 A FR0758001 A FR 0758001A FR 0758001 A FR0758001 A FR 0758001A FR 2921561 A1 FR2921561 A1 FR 2921561A1
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- skin
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- 239000000203 mixture Substances 0.000 title claims abstract description 40
- 239000002537 cosmetic Substances 0.000 title claims abstract description 11
- 239000006286 aqueous extract Substances 0.000 claims abstract description 26
- 239000000284 extract Substances 0.000 claims abstract description 23
- 241000893955 Blidingia minima Species 0.000 claims abstract description 8
- 241000295519 Laminaria ochroleuca Species 0.000 claims abstract description 8
- 241000983746 Saccharina latissima Species 0.000 claims abstract description 8
- 230000000699 topical effect Effects 0.000 claims abstract description 4
- QNZANUZIBYJBIN-XSWJXKHESA-N (3s)-3-[[(2s)-2-acetamido-5-amino-5-oxopentanoyl]amino]-4-[[(2s)-1-[[(1s)-1-carboxy-2-(1h-imidazol-5-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Chemical compound NC(=O)CC[C@H](NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(O)=O)CC1=CN=CN1 QNZANUZIBYJBIN-XSWJXKHESA-N 0.000 claims description 8
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- 229940042585 tocopherol acetate Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9722—Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
- A61K2800/884—Sequential application
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Composition cosmétique topique comprenant :- un extrait aqueux d'une algue dénommée Blidingia Minima,- un extrait aqueux d'une algue dénommée Laminaria Saccharina,- un extrait huileux d'une algue dénommée Laminaria Ochroleuca.A topical cosmetic composition comprising: - an aqueous extract of an alga called Blidingia Minima, - an aqueous extract of an alga called Laminaria Saccharina, - an oily extract of an alga called Laminaria Ochroleuca.
Description
COMPOSITION COSMETIOUE DESTINEE A AMELIORER L'ETAT DE LA PEAU COSMETIC COMPOSITION FOR IMPROVING THE CONDITION OF THE SKIN
L'invention a pour objet une nouvelle composition cométique contenant un mélange de constituants destinés à améliorer l'état de la peau en agissant sur un certain nombre de dysfonctionnements. The subject of the invention is a novel cometic composition containing a mixture of constituents intended to improve the state of the skin by acting on a certain number of dysfunctions.
Dans la présente invention la notion d'amélioration de l'état de la peau désigne notamment l'amélioration de : - son éclat par le biais de son état d'hydratation, - sa fermeté par le biais de la qualité de ses tissus de soutien, - son apaisement par le biais du stress qu'elle subit, - sa transparence par le biais de la finesse de son grain. In the present invention, the notion of improving the state of the skin designates in particular the improvement of: - its radiance by virtue of its state of hydration, - its firmness through the quality of its supporting tissues - its appeasement through the stress it undergoes - its transparency through the fineness of its grain.
L'ensemble de ces dysfonctionnements est en général corrigé au cas par cas au moyen de compositions cosmétiques qui présentent l'inconvénient de créer un déséquilibre du métabolisme des cellules présentes dans l'épiderme. Ces cellules fonctionnent selon un cycle comportant essentiellement 4 phases distinctes que sont : - la nutrition correspondant aux besoins en eau, sels minéraux, vitamines etc...de la cellule, - la construction correspondant à la synthèse des protéines, - la détoxification correspondant à l'élimination des déchets produits par la cellule, - la régénération correspondant à la multiplication des cellules. All of these dysfunctions are generally corrected case by case by means of cosmetic compositions which have the disadvantage of creating an imbalance of the metabolism of the cells present in the epidermis. These cells function in a cycle comprising essentially 4 distinct phases that are: - the nutrition corresponding to the need for water, mineral salts, vitamins, etc., of the cell, - the construction corresponding to the synthesis of the proteins, - the detoxification corresponding to the elimination of the waste produced by the cell, - the regeneration corresponding to the multiplication of the cells.
Or, il apparaît que la rupture de cet équilibre au niveau de l'une ou de l'autre de ces phases entraîne un dysfonctionnement visible au niveau de la peau. Il s'agit d'un état déshydraté en cas de manque de nutriments, d'une hyperséborrhée en cas de détoxification affaiblie, d'une altération des structures en cas de construction défaillante et d'un stress cellulaire entraînant une hyper réactivité cellulaire en cas d'absence de régénération. However, it appears that the rupture of this equilibrium at one or the other of these phases causes a visible dysfunction in the skin. It is a dehydrated state in the event of lack of nutrients, hyperseborrhoea in the event of weakened detoxification, structural alteration in case of faulty construction and cellular stress leading to cellular hyper reactivity in case lack of regeneration.
L'équilibre du cycle cellulaire peut être mis en évidence par la technique dite de photographie kirlian . Cette photographie montre la répartition de l'énergie dans la cellule via des zones de lumière désignées strimers réparties autour d'un cercle. Une répartition homogène et une intensité élevée des strimers sont le signe d'un équilibre cellulaire satisfaisant. La figure 1 représente dans ce sens le cercle Kirlian d'une cellule jeune. Au contraire, une répartition aléatoire et une intensité limitée des strimers sont le signe d'un déséquilibre du cycle cellulaire. La figure 2 représente dans ce sens le cercle Kirlian d'une cellule âgée. The balance of the cell cycle can be highlighted by the so-called kirlian photography technique. This photograph shows the distribution of energy in the cell via light zones designated strimers distributed around a circle. A homogeneous distribution and a high intensity of the strimers are the sign of a satisfactory cellular equilibrium. Figure 1 represents in this sense the Kirlian circle of a young cell. On the contrary, a random distribution and a limited intensity of the strimers are the sign of an imbalance of the cell cycle. Figure 2 represents in this sense the Kirlian circle of an aged cell.
Plutôt que d'agir directement et exclusivement sur les dysfonctionnements visibles de la peau, ce que font aujourd'hui la plupart des compositions cosmétiques, le Demandeur a cherché à rétablir au préalable l'équilibre cellulaire de l'épiderme. Plus précisément, l'objectif de l'invention a été de développer une composition rétablissant l'équilibre cellulaire en agissant directement sur le cycle cellulaire de manière à rendre les cellules réceptives aux effets de composants appliqués ultérieurement ou simultanément et destinés pour leur part, à lutter directement contre les dysfonctionnements visibles de la peau. Rather than acting directly and exclusively on the visible dysfunction of the skin, which is what most cosmetic compositions do today, the Applicant sought to restore the cellular equilibrium of the epidermis beforehand. More specifically, the object of the invention has been to develop a composition that restores the cell balance by acting directly on the cell cycle so as to render the cells receptive to the effects of components applied subsequently or simultaneously and intended for their part, to fight directly against visible dysfunctions of the skin.
Pour ce faire, le Demandeur a mis au point une nouvelle composition cosmétique topique comprenant : - un extrait aqueux d'une algue dénommée Blidingia Minima, - un extrait aqueux d'une algue dénommée Laminaria Saccharina, - un extrait huileux d'une algue dénommée Laminaria Ochroleuca, - éventuellement, un extrait aqueux de plancton. To do this, the Applicant has developed a new topical cosmetic composition comprising: an aqueous extract of an alga called Blidingia Minima, an aqueous extract of an alga called Laminaria Saccharina, an oily extract of a so-called algae Laminaria Ochroleuca, - optionally, an aqueous extract of plankton.
Dans un mode de réalisation avantageux, la composition contient les quatre extraits ci-avant identifiés. In an advantageous embodiment, the composition contains the four extracts identified above.
Le Demandeur a démontré qu'une telle composition permettait de rétablir l'équilibre du cycle cellulaire The Applicant has demonstrated that such a composition can restore the balance of the cell cycle
Bien entendu l'ensemble de ces extraits sont obtenus dans des conditions bien connues de l'homme du métier, avantageusement à partir d'algues fraîches par extraction en milieu aqueux, éventuellement en présence d'alcool. Les conditions d'extraction ne nécessitent donc pas d'être d'avantage décrites dans le détail. Of course all of these extracts are obtained under conditions well known to those skilled in the art, preferably from fresh algae by extraction in aqueous medium, optionally in the presence of alcohol. The extraction conditions do not therefore need to be described in detail.
En pratique, la composition cosmétique topique de l'invention contient (en pourcentage en poids) : - de 0.2 à 5%, de préférence de 0.5 à 2% en poids d'un extrait aqueux de Blidingia Minima, - de 0.2 à 5%, de préférence de 0.5 à 2% en poids d'un extrait aqueux de Laminaria Saccharina, - de 0.2 à 5%, de préférence de 0.5 à 2% en poids d'un extrait huileux de Laminaria Ochroleuca, - de 0.05 à 5%, de préférence de 0.05 à 2% en poids d'un extrait aqueux de plancton. In practice, the topical cosmetic composition of the invention contains (in percentage by weight): from 0.2 to 5%, preferably from 0.5 to 2% by weight of an aqueous extract of Blidingia Minima, from 0.2 to 5% preferably from 0.5 to 2% by weight of an aqueous extract of Laminaria Saccharina, from 0.2 to 5%, preferably from 0.5 to 2% by weight of an oily extract of Laminaria Ochroleuca, of from 0.05 to 5% preferably from 0.05 to 2% by weight of an aqueous extract of plankton.
Dans un mode de réalisation avantageux, la composition de l'invention contient en outre au moins un composant capable d'agir directement sur les dysfonctionnements visibles de la peau, tels que comme déjà mentionné, hydratation, hyperséborrhée, altération des structures, stress cellulaire, sans pour autant rompre l'équilibre cellulaire. In an advantageous embodiment, the composition of the invention also contains at least one component capable of acting directly on the visible dysfunctions of the skin, such as, as already mentioned, hydration, hyperseborrhoea, structural alteration, cellular stress, without breaking the cell balance.
En d'autres termes, la composition contient en outre au moins un, avantageusement les quatre constituants suivants respectivement : - un extrait aqueux de soja induisant la synthèse d'aquaporines et assurant par la même, une meilleure circulation de l'eau dans la peau et des éléments nutritifs dans la cellule, - un extrait alcoolique de champignon riche en acide agarique, tel que par exemple un extrait de Polyporus Officinalis, extrait présentant une action astringente permettant de resserrer les pores de la peau et ainsi de limiter la sécrétion de sébum au niveau de la surface cutanée ainsi que la prolifération microbienne à l'intérieur du canal pilosébacé, - un peptide, tel que par exemple un tétrapeptide, éventuellement acétylé apte à stimuler la synthèse de collagène en vue de l'amélioration de la qualité des tissus de soutien de la peau, avantageusement le Acétyl Tétrapeptide-9: N-Acétyl L-Glutaminyl L- Aspartyl L-Valyl L-Histidine, - un saccharide, tel que par exemple le rhamnose permettant de limiter les phénomènes d'inflammation. In other words, the composition also contains at least one, advantageously, the following four constituents respectively: an aqueous soy extract inducing the synthesis of aquaporins and thereby ensuring better circulation of the water in the skin and nutrients in the cell; an alcoholic extract of a mushroom rich in agaric acid, such as, for example, an extract of Polyporus Officinalis, extract having an astringent action making it possible to tighten the pores of the skin and thus to limit the secretion of sebum at the level of the cutaneous surface as well as the microbial proliferation inside the pilosebaceous canal; a peptide, such as, for example, a tetrapeptide, optionally acetylated capable of stimulating the synthesis of collagen with a view to improving the quality of the tissues skin support, advantageously Acetyl tetrapeptide-9: N-Acetyl L-Glutaminyl L-Aspartyl L-Valyl L-Histidine, - a saccharide, such as ee for example rhamnose to limit the phenomena of inflammation.
Dans un mode de réalisation avantageux, la composition contient en outre, en poids de la composition totale : - entre 0.0005 et 1%, avantageusement entre 0.005 et 0.1% d'un extrait aqueux de soja, - entre 0.05 et 2%, avantageusement entre 0.1 et 1% d'un extrait alcoolique de champignon, avantageusement un extrait de Polyporus Officinalis, - entre 1 et 10%, avantageusement entre 2 et 5% d'un tétrapeptide acétylé par exemple Acétyl Tétrapeptide-9 : N-Acétyl L-Glutaminyl L-Aspartyl L-Valyl L-Histidine, -entre 0.0005 et 1%, avantageusement entre 0.005 et 0.1% de rhamnose. In an advantageous embodiment, the composition additionally contains, by weight of the total composition: between 0.0005 and 1%, advantageously between 0.005 and 0.1% of an aqueous soy extract, between 0.05 and 2%, advantageously between 0.1 and 1% of an alcoholic fungus extract, advantageously an extract of Polyporus Officinalis, between 1 and 10%, advantageously between 2 and 5% of an acetylated tetrapeptide, for example acetyl tetrapeptide-9: N-acetyl L-glutaminyl L-Aspartyl L-Valyl L-Histidine, between 0.0005 and 1%, advantageously between 0.005 and 0.1% of rhamnose.
Bien entendu, la composition de l'invention peut contenir d'autres ingrédients tels que notamment des agents anti-radicalaires (par exemple acide ascorbique et dérivés, SOD, acétate de tocophérol, flavonoides), agent anti-oxydant (BHT, etc..), agent sequestrants (EDTA..). Of course, the composition of the invention may contain other ingredients such as in particular anti-radical agents (for example ascorbic acid and derivatives, SOD, tocopherol acetate, flavonoids), anti-oxidizing agent (BHT, etc.). ), sequestering agent (EDTA ..).
De même, la composition peut contenir tout excipient de formulation adéquat pour la rendre utilisable sous la forme d'un sérum notamment et en particulier de l'eau et des matières grasses telles que par exemple glycérine, silicones et dérivés. Similarly, the composition may contain any excipient of suitable formulation to make it usable in the form of a particular serum and in particular water and fats such as for example glycerin, silicones and derivatives.
15 Dans un mode de réalisation particulier, la composition contient : - de 0.2 à 5%, de préférence de 0.5 à 2% en poids d'un extrait aqueux de Blidingia Minima, - de 0.2 à 5%, de préférence de 0.5 à 2% en poids d'un extrait aqueux de Laminaria Saccharina, 20 - de 0.2 à 5%, de préférence de 0.5 à 2% en poids d'un extrait huileux de Laminaria Ochroleuca, - de 0.05 à 5%, de préférence de 0.05 à 2% en poids d'un extrait aqueux de plancton. - entre 0.0005 et 1%, avantageusement entre 0.005 et 0.1% d'un extrait aqueux 25 de soja, - entre 0.05 et 2%, avantageusement entre 0.1 et 1% d'un extrait alcoolique de champignon, avantageusement un extrait de Polyporus Officinalis, , - entre 1 et 10%, avantageusement entre 2 et 5% d'un tétrapeptide acétylé par exemple Acétyl Tétrapeptide-9 : N-Acétyl L-Glutaminyl L-Aspartyl L-Valyl 30 L-Histidine, - entre 0.0005 et 1%, avantageusement entre 0.005 et 0.1% de rhamnose, - entre 65 et 85% en poids d'eau, - entre 5 et 20% en poids de matière grasse. In a particular embodiment, the composition contains: from 0.2 to 5%, preferably from 0.5 to 2% by weight of an aqueous extract of Blidingia Minima, from 0.2 to 5%, preferably from 0.5 to 2% by weight. % by weight of an aqueous extract of Laminaria Saccharina, from 0.2 to 5%, preferably from 0.5 to 2% by weight, of an oily extract of Laminaria Ochroleuca, of from 0.05 to 5%, preferably from 0.05 to 2% by weight of an aqueous extract of plankton. between 0.0005 and 1%, advantageously between 0.005 and 0.1% of an aqueous soy extract, between 0.05 and 2%, advantageously between 0.1 and 1% of an alcoholic mushroom extract, advantageously an extract of Polyporus Officinalis, between 1 and 10%, advantageously between 2 and 5% of an acetylated tetrapeptide, for example acetyl tetrapeptide-9: N-acetyl L-Glutaminyl L-Aspartyl L-Valyl L-Histidine, between 0.0005 and 1%, advantageously between 0.005 and 0.1% of rhamnose, between 65 and 85% by weight of water, between 5 and 20% by weight of fat.
35 Le Demandeur a par ailleurs démontré que la mise en oeuvre de la composition de l'invention permettait d'optimiser l'action d'une composition cosmétique distincte 10 appliquée ultérieurement. En d'autres termes et comme déjà dit, la composition de l'invention permet de rétablir l'équilibre du cycle cellulaire et de rendre la peau réceptive à l'action d'une composition ultérieure. The Applicant has furthermore demonstrated that the use of the composition of the invention makes it possible to optimize the action of a different cosmetic composition subsequently applied. In other words and as already said, the composition of the invention makes it possible to restore the equilibrium of the cell cycle and to make the skin receptive to the action of a subsequent composition.
Dès lors, la composition peut être mise en oeuvre dans le cadre d'un protocole de soin. L'invention a donc également pour objet un procédé de traitement cosmétique de la peau en vue d'en améliorer l'état et consistant, dans un premier temps, à appliquer ladite composition sur la peau, puis dans un second temps, à appliquer une seconde composition destinée à corriger un dysfonctionnement visible de la peau tel que par exemple déshydratation ou encore hyperséborrhée. Therefore, the composition can be implemented as part of a care protocol. The subject of the invention is therefore also a process for the cosmetic treatment of the skin with a view to improving its state and consisting, in a first step, in applying said composition to the skin, then in a second step, in applying a second composition for correcting a visible dysfunction of the skin such as for example dehydration or hyperseborrhoea.
L'invention et les avantages qui en découlent ressortiront bien des exemples suivants à l'appui des figures annexées. The invention and the advantages thereof will emerge from the following examples in support of the appended figures.
La figure 1 est une photographie représentant le cercle Kirlian d'une cellule jeune. La figure 2 est une photographie représentant le cercle Kirlian d'une cellule âgée. La figure 3 est une photographie représentant le cercle Kirlian d'une cellule âgée traitée par le concentré cellulaire. La figure 4 est une représentation graphique de l'évaluation in vivo de la fermeté cutanée. Les figures 5 et 6 sont des photographies réalisées sur prises d'empreintes au niveau du visage avant traitement (figure 6) et après traitement (figure 5), par le concentré cellulaire. La figure 7 est une représentation graphique de l'effet du concentré cellulaire sur l'apaisement de la peau. La figure 8 est une représentation graphique de l'effet du concentré cellulaire sur un soin associé. Figure 1 is a photograph showing the Kirlian circle of a young cell. Figure 2 is a photograph showing the Kirlian circle of an aged cell. Figure 3 is a photograph showing the Kirlian circle of an aged cell treated with the cell concentrate. Figure 4 is a graphical representation of the in vivo evaluation of cutaneous firmness. Figures 5 and 6 are photographs taken on fingerprints in the face before treatment (Figure 6) and after treatment (Figure 5), by the cell concentrate. Figure 7 is a graphical representation of the effect of the cell concentrate on the soothing of the skin. Figure 8 is a graphical representation of the effect of cell concentrate on associated care.
U La composition testée concentré cellulaire U The composition tested cell concentrate
La composition testée dans les essais qui suivent désignée concentré cellulaire à la composition suivante en pourcentage en poids: extrait aqueux de Blidingia Minima 1 extrait aqueux de Laminaria Saccharina 1 extrait huileux de Laminaria Ochroleuca 1 extrait aqueux de plancton 0.5 extrait aqueux de soja 0.5 extrait alcoolique de Polyporus 0.5 Officinalis tétrapeptide acétylé 1 rhamnose 0.5 eau 74 glycérine + silicone 20 II/ Photo kirlian d'une cellule âgée traitée par le concentré cellulaire The composition tested in the following tests designated cell concentrate to the following composition as a percentage by weight: aqueous extract of Blidingia Minima 1 aqueous extract of Laminaria Saccharina 1 oily extract of Laminaria Ochroleuca 1 aqueous extract of plankton 0.5 aqueous extract of soy 0.5 alcoholic extract of Polyporus 0.5 Officinalis tetrapeptide acetylated 1 rhamnose 0.5 water 74 glycerin + silicone 20 II / Photo kirlian of an aged cell treated with cell concentrate
Les énergies nécessaires et dispensées par le cycle cellulaire peuvent être mises en 10 lumière par la photo Kirlian ou photographie de type électrographie dynamique. Cette photo met en évidence d'une part la valeur énergétique du concentré cellulaire et d'autre part, renseigne sur les zones d'activités du concentré cellulaire dans la cellule. On peut ainsi visualiser, via les strimers de la photo Kirlain, le degré d'apport et d'utilisation de l'énergie par la cellule. Si équilibre il y a dans la cellule, il sera 15 symbolisé par un cercle Kirlian homogène, aux strimers intenses et relativement fournis. Ce sera également le symbole d'un cycle cellulaire en fonctionnement optimal et d'une vibration équilibrée avec l'environnement. The necessary energies provided by the cell cycle can be illuminated by the Kirlian photo or dynamic electrography type photograph. This photo highlights on the one hand the energy value of the cell concentrate and on the other hand, provides information on the activity zones of the cell concentrate in the cell. It is thus possible to visualize, via the strimers of the Kirlain photo, the degree of contribution and use of the energy by the cell. If there is equilibrium in the cell, it will be symbolized by a homogeneous Kirlian circle, with intense and relatively provided strimers. It will also be the symbol of an optimal functioning cell cycle and a balanced vibration with the environment.
Les figures 1, 2 et 3 sont des photos du cercle kirlian d'une cellule jeune (figure 1), 20 cellule âgée (figure 2) et cellule âgée traitée avec le concentré cellulaire (figure 3). Comme le montre cette dernière, le concentré cellulaire permet de rétablir l'équilibre du cycle cellulaire avec une zone d'activité homogène.5 III/ Efficacité de la composition de l'invention sur l'amélioration de l'état de la peau Figures 1, 2 and 3 are photographs of the kirlian circle of a young cell (Figure 1), aged cell (Figure 2) and aged cell treated with the cell concentrate (Figure 3). As shown by the latter, the cell concentrate makes it possible to restore the equilibrium of the cell cycle with a zone of homogeneous activity. III / Effectiveness of the Composition of the Invention on Improving the State of the Skin
1/ Eclat de la peau : pouvoir hydratant But évaluer et comparer l'état d'hydratation naturel de la peau avant et après utilisation du Concentré Cellulaire en application biquotidienne pendant 28 jours. Suiets : 18 volontaires. Protocole : mesures réalisées à l'aide d'un cornéomètre, au minimum 15mn après 10 nettoyage de la peau, rinçage à l'eau et séchage. Résultats : Le Concentré Cellulaire permet d'augmenter le taux d'hydratation cutané naturel de quasiment 15% par rapport au taux basal et ceci après une utilisation bi quotidienne pendant 1 mois. 15 2/ Fermeté de la peau in vivo 1 / Skin radiance: moisturizing power Aim to evaluate and compare the natural state of hydration of the skin before and after use of the Cellular Concentrate twice daily for 28 days. Suiets: 18 volunteers. Protocol: measurements carried out using a corneometer, at least 15 minutes after cleaning the skin, rinsing with water and drying. Results: The Cellular Concentrate makes it possible to increase the rate of natural skin hydration by almost 15% compared to the basal rate and this after a bi daily use for 1 month. 2 / Skin firmness in vivo
But évaluer les propriétés biomécaniques de la peau, notamment la fermeté, après utilisation pendant 1 mois du Concentré Cellulaire, en conditions normales. 20 Suiets : 18 volontaires. Protocole : mesure des propriétés biomécaniques à l'aide du cutomètre qui va évaluer le relâchement de la peau (plus le relâchement diminue, plus la peau est tendue et ferme). Résultats : 25 Le produit Concentré Cellulaire permet une amélioration significative de la fermeté de la peau (+13%) après utilisation bi quotidienne pendant 1 mois (figure 4). To evaluate the biomechanical properties of the skin, especially the firmness, after 1 month use of the Cellular Concentrate, under normal conditions. 20 Suiets: 18 volunteers. Protocol: measurement of biomechanical properties using the cutometer which will evaluate the relaxation of the skin (the more the relaxation decreases, the more the skin is tense and firm). Results: The Cellular Concentrate product provides a significant improvement in the firmness of the skin (+ 13%) after daily bi use for 1 month (FIG. 4).
3/ Transparence de la peau 3 / Transparency of the skin
30 But évaluer et comparer le grain de la peau avant et après utilisation du Concentré Cellulaire en application biquotidienne pendant 28 jours. Suiets : 18 volontaires. Protocole : photos réalisées sur prises d'empreintes au niveau du visage. Résultats : comme le montre la figure 6, le grain de la peau est significativement affiné 35 par rapport à la peau non traitée (figure 5). La peau est plus fine, plus nette, plus éclatante, plus transparente. / Apaisement de la peau 30 Aim to evaluate and compare skin grain before and after using Cellular Concentrate twice daily for 28 days. Suiets: 18 volunteers. Protocol: photos taken on fingerprints on the face. Results: As shown in Figure 6, the skin grain is significantly refined compared to untreated skin (Figure 5). The skin is thinner, sharper, more radiant, more transparent. / Soothing of the skin
But : évaluer l'apaisement de la peau après utilisation du concentré cellulaire, deux fois 5 par jour, pendant 28 jours. Suiets : 18 volontaires. Protocole : Questionnaire d'auto-évaluation Résultats : comme le montre la figure 7, le concentré cellulaire apaise entre 80 et 90% des sujets. 10 5/ Optimisation de l'efficacité des soins associés Aim: to evaluate the soothing of the skin after using the cell concentrate twice a day for 28 days. Suiets: 18 volunteers. Protocol: Self-Assessment Questionnaire Results: As shown in Figure 7, cell concentrate soothes between 80 and 90% of subjects. 5 / Optimizing the effectiveness of associated care
But : évaluer et comparer, en double aveugle, la cinétique (t0, t2h, t4h, t6h, t8h) d'hydratation du Concentré Cellulaire couplé à la Crème Hydra Ressourçante 15 commercialisée par Institut Esthederm versus la Crème Hydra Ressourçante après une application unique. Suiets : 10 volontaires (âgés de 23 à 55 ans) ayant la peau sèche ou moyennement hydratée au niveau des avant-bras. Protocole : mesures réalisées à l'aide d'un cornéomètre.Aim: to evaluate and compare, in double blind, the kinetics (t0, t2h, t4h, t6h, t8h) of hydration of the Cellular Concentrate coupled with the Hydra Ressourçante Cream 15 marketed by Institut Esthederm versus Hydra Ressourçante Cream after a single application. Suiets: 10 volunteers (aged 23 to 55 years old) with dry or moderately hydrated skin in the forearms. Protocol: measurements using a corneometer.
20 Résultats : comme le montre la figure 8, le Concentré Cellulaire couplé à la Crème Hydra Ressourçante permet d'augmenter le taux d'hydratation cutanée de quasiment 70% en 2 heures et cette action persiste jusqu'à 8h (+40% seul, +50% couplé). 8 Results: as shown in FIG. 8, the Cellular Concentrate coupled with the Hydra Ressourçante Cream makes it possible to increase the cutaneous hydration rate by almost 70% in 2 hours and this action persists for up to 8 hours (+ 40% alone, + 50% paired). 8
Claims (7)
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PCT/FR2008/051663 WO2009047443A2 (en) | 2007-10-02 | 2008-09-17 | Cosmetic composition for improving skin condition |
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FR2980698A1 (en) * | 2011-09-29 | 2013-04-05 | Gelyma | Use of a combination of macroalgae and microalgae extracts for preparing cosmetic and/or dermocosmetic product for topical application on oily skin and/or acne skin, and for fighting against free radicals and limiting irritation of skin |
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US9676696B2 (en) * | 2009-01-29 | 2017-06-13 | The Procter & Gamble Company | Regulation of mammalian keratinous tissue using skin and/or hair care actives |
CA2804917C (en) * | 2010-07-22 | 2017-05-30 | The Procter & Gamble Company | Methods for improving the appearance of hyperpigmented spot(s) using an extract of laminaria saccharina |
KR20150048918A (en) * | 2010-07-22 | 2015-05-07 | 더 프록터 앤드 갬블 캄파니 | Methods for improving the appearance of hyperpigmented spot(s) with multiple actives |
KR101690959B1 (en) * | 2010-07-22 | 2016-12-29 | 더 프록터 앤드 갬블 캄파니 | Compositions and methods for inhibiting par2 activation of keratinocytes |
JP6050572B2 (en) * | 2011-08-10 | 2016-12-21 | ロート製薬株式会社 | Elastic fiber formation promoter |
JP6050573B2 (en) * | 2011-08-10 | 2016-12-21 | ロート製薬株式会社 | LTBP-4 production promoter |
JP5719050B2 (en) * | 2014-02-28 | 2015-05-13 | ザ プロクター アンド ギャンブルカンパニー | Compositions and methods for inhibiting keratinocyte par2 activation |
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