KR20020075388A - 에스트로겐 수용체의 조절 화합물 및 조절 방법 - Google Patents
에스트로겐 수용체의 조절 화합물 및 조절 방법 Download PDFInfo
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- KR20020075388A KR20020075388A KR1020027008569A KR20027008569A KR20020075388A KR 20020075388 A KR20020075388 A KR 20020075388A KR 1020027008569 A KR1020027008569 A KR 1020027008569A KR 20027008569 A KR20027008569 A KR 20027008569A KR 20020075388 A KR20020075388 A KR 20020075388A
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
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- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
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- Immunology (AREA)
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- Oncology (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47577699A | 1999-12-30 | 1999-12-30 | |
| US09/475,776 | 1999-12-30 | ||
| US09/492,939 | 2000-01-27 | ||
| US09/492,939 US6291456B1 (en) | 1998-12-30 | 2000-01-27 | Compounds and methods for modulation of estrogen receptors |
| US09/611,156 | 2000-07-06 | ||
| US09/611,156 US6331562B1 (en) | 1998-12-30 | 2000-07-06 | Compounds and methods for modulation of estrogen receptors |
| PCT/US2000/035671 WO2001049673A2 (en) | 1999-12-30 | 2000-12-29 | Compounds and methods for modulation of estrogen receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20020075388A true KR20020075388A (ko) | 2002-10-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020027008569A Abandoned KR20020075388A (ko) | 1999-12-30 | 2000-12-29 | 에스트로겐 수용체의 조절 화합물 및 조절 방법 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1246814B1 (https=) |
| JP (1) | JP2003519219A (https=) |
| KR (1) | KR20020075388A (https=) |
| CN (1) | CN1281598C (https=) |
| AT (1) | ATE289300T1 (https=) |
| AU (1) | AU781282B2 (https=) |
| CA (1) | CA2396059A1 (https=) |
| DE (1) | DE60018215T2 (https=) |
| DK (1) | DK1246814T3 (https=) |
| ES (1) | ES2238034T3 (https=) |
| IL (1) | IL150463A0 (https=) |
| PT (1) | PT1246814E (https=) |
| WO (1) | WO2001049673A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020010504A (ko) * | 2000-07-28 | 2002-02-04 | 실버스타인 아써 에이. | 백내장을 치료하기 위한 조성물 및 방법 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO5271709A1 (es) * | 2000-01-12 | 2003-04-30 | Pfizer Prod Inc | Composiciones y procedimientos para el y tratamiento de afecciones que responden a estrogenos |
| EP1281710A1 (en) * | 2001-08-03 | 2003-02-05 | CHIESI FARMACEUTICI S.p.A. | 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof |
| US7148252B2 (en) * | 2001-10-03 | 2006-12-12 | Signal Pharmaceuticals, Llc | Use of benzopyranones for treating or preventing a primary brain cancer or a brain metastasis |
| EA007382B1 (ru) | 2001-11-19 | 2006-10-27 | Эли Лилли Энд Компани | Замещенные бензопираны в качестве селективных агонистов бета-рецептора эстрогена |
| AU2005202072B2 (en) * | 2001-11-29 | 2008-10-23 | Gtx, Inc. | Prevention and treatment of androgen-deprivation induced conditions |
| MXPA04005112A (es) * | 2001-11-29 | 2005-04-29 | Gtx Inc | Prevencion y tratamiento de osteoporosis inducida por privacion de androgeno. |
| US7524866B2 (en) | 2001-11-29 | 2009-04-28 | Gtx, Inc. | Prevention and treatment of androgen—deprivation induced osteoporosis |
| EP1497277A1 (en) * | 2002-04-19 | 2005-01-19 | Signal Pharmaceuticals, Inc. | Benzopyranone compounds, compositions thereof, and methods of treatment therewith |
| US7091235B2 (en) | 2002-10-15 | 2006-08-15 | Signal Pharmaceuticals, Llc | Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer |
| US7674783B2 (en) * | 2002-11-22 | 2010-03-09 | Dimera Inc. | Estrogen beta receptor agonists to prevent or reduce the severity of cardiovascular disease |
| ATE457308T1 (de) | 2003-04-21 | 2010-02-15 | Lilly Co Eli | Substituierte benzopyrane als selektive antagonisten am östrogenrezeptor-beta |
| SI1626974T1 (sl) | 2003-04-21 | 2009-02-28 | Lilly Co Eli | Substituirani benzopirani kot selektivni agonistiestrogenskega receptorja beta |
| US7098340B2 (en) | 2003-05-14 | 2006-08-29 | Warner Lambert Company Llc | Benzyl sulfonamide derivatives |
| CA2538874A1 (en) * | 2003-09-15 | 2005-03-31 | Signal Pharmaceuticals, Llc | Benzopyranone compounds, compositions thereof, and methods of treatment therewith |
| CA2595472A1 (en) * | 2005-01-21 | 2006-07-27 | Janssen Pharmaceutica N.V. | Novel coumarin derivatives as ion channel openers |
| CA2656067C (en) * | 2006-06-23 | 2014-08-12 | Radius Health, Inc. | Treatment of vasomotor symptoms with selective estrogen receptor modulators |
| EP2568806B1 (en) | 2010-05-12 | 2016-05-11 | Radius Health, Inc. | Therapeutic regimens |
| US9133182B2 (en) | 2010-09-28 | 2015-09-15 | Radius Health, Inc. | Selective androgen receptor modulators |
| US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
| FI3834824T3 (fi) | 2014-03-28 | 2025-12-05 | Univ Duke | Estrogeenireseptoripositiivisen rintasyövän hoito selektiivisellä estrogeenireseptorin modulaattorilla |
| CN105801544A (zh) * | 2016-04-18 | 2016-07-27 | 中国药科大学 | 3-芳基-4-芳香胺-香豆素衍生物及其制备方法和医药用途 |
| CN105801543B (zh) * | 2016-04-18 | 2019-08-02 | 中国药科大学 | 4-芳香胺-香豆素衍生物及其制备方法和医药用途 |
| LT3474841T (lt) | 2016-06-22 | 2022-06-10 | Ellipses Pharma Ltd | Ar+ krūties vėžio gydymo būdai |
| CN106727637A (zh) * | 2016-12-27 | 2017-05-31 | 郑州郑先医药科技有限公司 | 一种治疗白内障的西药组合物及其用途 |
| CN106492204A (zh) * | 2016-12-27 | 2017-03-15 | 郑州郑先医药科技有限公司 | 一种治疗白内障的药物组合物 |
| KR102707399B1 (ko) | 2017-01-05 | 2024-09-13 | 래디어스 파마슈티컬스, 인코포레이티드 | Rad1901-2hcl의 다형 형태 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5883118A (en) * | 1996-01-11 | 1999-03-16 | Nova Nordisk A/S | Prostatic carcinoma |
| US5726202A (en) * | 1996-01-11 | 1998-03-10 | Novo Nordisk A/S | Benign prostatic hypertrophy |
| IL124882A0 (en) * | 1996-01-11 | 1999-01-26 | Novo Nordisk As | Use of 3, 4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of menopausal symptoms |
| EP1140889B1 (en) * | 1998-12-30 | 2003-08-27 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
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2000
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- 2000-12-29 WO PCT/US2000/035671 patent/WO2001049673A2/en not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020010504A (ko) * | 2000-07-28 | 2002-02-04 | 실버스타인 아써 에이. | 백내장을 치료하기 위한 조성물 및 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001049673A3 (en) | 2001-12-06 |
| ES2238034T3 (es) | 2005-08-16 |
| AU3077101A (en) | 2001-07-16 |
| EP1246814A2 (en) | 2002-10-09 |
| CN1437591A (zh) | 2003-08-20 |
| CA2396059A1 (en) | 2001-07-12 |
| DK1246814T3 (da) | 2005-05-30 |
| PT1246814E (pt) | 2005-07-29 |
| AU781282B2 (en) | 2005-05-12 |
| CN1281598C (zh) | 2006-10-25 |
| HK1058521A1 (en) | 2004-05-21 |
| DE60018215D1 (de) | 2005-03-24 |
| DE60018215T2 (de) | 2006-02-09 |
| IL150463A0 (en) | 2002-12-01 |
| JP2003519219A (ja) | 2003-06-17 |
| EP1246814B1 (en) | 2005-02-16 |
| ATE289300T1 (de) | 2005-03-15 |
| WO2001049673A2 (en) | 2001-07-12 |
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