KR20010043322A - 미코박테리아성 억제제 - Google Patents

미코박테리아성 억제제 Download PDF

Info

Publication number
KR20010043322A
KR20010043322A KR1020007012290A KR20007012290A KR20010043322A KR 20010043322 A KR20010043322 A KR 20010043322A KR 1020007012290 A KR1020007012290 A KR 1020007012290A KR 20007012290 A KR20007012290 A KR 20007012290A KR 20010043322 A KR20010043322 A KR 20010043322A
Authority
KR
South Korea
Prior art keywords
dione
group
nonyl
methyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020007012290A
Other languages
English (en)
Korean (ko)
Inventor
미나크시 발가네시
칸타라즈 에티라줄루
바비타 신그흐 간굴리
라마찬드란 자나키라만
파르빈데르 카우르
란가라오 카지팔야
산토시 난단
라마누줄루 폰디 무루가빤
나라야난 라마무르티
발라수브라마니안 벤카타라만
Original Assignee
아스트라제네카 악티에볼라그
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9802118A external-priority patent/SE9802118D0/xx
Application filed by 아스트라제네카 악티에볼라그 filed Critical 아스트라제네카 악티에볼라그
Publication of KR20010043322A publication Critical patent/KR20010043322A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
KR1020007012290A 1998-05-05 1999-05-03 미코박테리아성 억제제 Ceased KR20010043322A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN969MA1998 1998-05-05
IN969/MAS/98 1998-05-05
SE9802118-1 1998-06-15
SE9802118A SE9802118D0 (sv) 1998-06-15 1998-06-15 Mycobacterial inhibitors
PCT/SE1999/000732 WO1999065483A1 (en) 1998-05-05 1999-05-03 Mycobacterial inhibitors

Publications (1)

Publication Number Publication Date
KR20010043322A true KR20010043322A (ko) 2001-05-25

Family

ID=26324850

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007012290A Ceased KR20010043322A (ko) 1998-05-05 1999-05-03 미코박테리아성 억제제

Country Status (14)

Country Link
US (1) US6476053B1 (cg-RX-API-DMAC10.html)
EP (1) EP1075261B1 (cg-RX-API-DMAC10.html)
JP (1) JP2002518324A (cg-RX-API-DMAC10.html)
KR (1) KR20010043322A (cg-RX-API-DMAC10.html)
CN (1) CN1201735C (cg-RX-API-DMAC10.html)
AT (1) ATE322898T1 (cg-RX-API-DMAC10.html)
AU (1) AU739140B2 (cg-RX-API-DMAC10.html)
BR (1) BR9910185A (cg-RX-API-DMAC10.html)
CA (1) CA2330667A1 (cg-RX-API-DMAC10.html)
DE (1) DE69930844T2 (cg-RX-API-DMAC10.html)
IL (1) IL139144A0 (cg-RX-API-DMAC10.html)
NO (1) NO20005548L (cg-RX-API-DMAC10.html)
NZ (1) NZ507620A (cg-RX-API-DMAC10.html)
WO (1) WO1999065483A1 (cg-RX-API-DMAC10.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2060259B1 (en) 2001-11-01 2010-01-20 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
KR20080034944A (ko) * 2005-08-19 2008-04-22 아스트라제네카 아베 결핵 치료용 피라졸론 유도체
GB0520368D0 (en) * 2005-10-06 2005-11-16 Univ Aston Antibacterial pyrrols
WO2010063617A1 (de) * 2008-12-04 2010-06-10 Basf Se Mischungen aus itaconsäure oder itaconsäurederivaten und primären aminen zur herstellung von 1,3- und 1,4-alkylmethylpyrrolidonen
PL3393530T3 (pl) * 2015-12-23 2022-12-05 Henkel Ag & Co. Kgaa Płyn do obróbki metali
CN107033060B (zh) * 2017-05-04 2020-01-14 浙江工业大学 一种n-取代顺丁烯二酰亚胺类化合物及其制备与抗菌应用
CN111465611B (zh) * 2017-12-01 2024-10-11 古德T细胞有限公司 预防或治疗脱发的组合物
CN119569636B (zh) * 2024-10-22 2026-03-27 南京吉星生物技术开发有限公司 一种吡咯啉二酮类化合物及其制备方法和杀菌剂应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883342A (en) * 1973-04-13 1975-05-13 Akzona Inc Plant growth regulators

Also Published As

Publication number Publication date
NZ507620A (en) 2003-05-30
AU739140B2 (en) 2001-10-04
AU4304199A (en) 2000-01-05
DE69930844D1 (de) 2006-05-24
CA2330667A1 (en) 1999-12-23
IL139144A0 (en) 2001-11-25
CN1201735C (zh) 2005-05-18
NO20005548L (no) 2000-12-04
EP1075261B1 (en) 2006-04-12
CN1308532A (zh) 2001-08-15
NO20005548D0 (no) 2000-11-03
WO1999065483A1 (en) 1999-12-23
US6476053B1 (en) 2002-11-05
EP1075261A1 (en) 2001-02-14
DE69930844T2 (de) 2006-12-28
ATE322898T1 (de) 2006-04-15
BR9910185A (pt) 2001-01-09
JP2002518324A (ja) 2002-06-25

Similar Documents

Publication Publication Date Title
JP4095676B2 (ja) 注意障害を治療するためのコリンエステラーゼ阻害剤の使用
AU629197B2 (en) Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
CN100391455C (zh) 靛红和羟吲哚衍生物的制药用途
CN112689633A (zh) 用于抑制Nav1.8的吡啶甲酰胺化合物
JPH06504779A (ja) 新規ｃｓａｉｄｓ
US6284772B1 (en) Indolo[2,1-B] quinazole-6,12-dione antimalarial compounds and methods of treating malaria therewith
WO1998006433A1 (en) MEDICINES COMPRISING Rho KINASE INHIBITOR
CZ283782B6 (cs) 2,4- a 2,5-substituované pyridin-N-oxidy, způsob jejich výroby a jejich použití
WO2002081447A1 (en) 3-cyclopentyloxy-4-methoxyphenyl-isothiazolinone derivatives and the use thereof
FI97544C (fi) Menetelmä lääkeaineina käyttökelpoisten 1-(pyrido/3,4-b/-1,4-oksatsin-4-yyli)-1H-indolien valmistamiseksi
US6476053B1 (en) Mycobacterial inhibitors
SK16792001A3 (sk) Spoločné proliečivá amlodipínu a atorvastatínu
WO2012054093A2 (en) Acyl piperidine inhibitors of soluble epoxide hydrolase
JP2003506436A (ja) Ｎｍｄａ−レセプターアンタゴニストとしての置換されたピロリジン−２，３，４−トリオン−３−オキシム誘導体
JP2021506810A (ja) フッ素化４−（置換アミノ）フェニルカルバメート誘導体
CA2048959C (en) 3-(1,2-benzisoxazol-3-yl)-4-pyridinamines and derivatives
DE69909592T2 (de) Verwendung von thiadiazolo[4,3-a]pyridine derivaten
AU5426900A (en) Optically active pyrrolopyridazine compounds
MXPA00010685A (en) Mycobacterial inhibitors
US4315934A (en) Organic compounds
JP2006503042A (ja) カルシウムチャンネル遮断薬
JPH0447678B2 (cg-RX-API-DMAC10.html)
HK1030885B (en) The use of isatin and oxindole derivatives in the preparation of a medicament for use in the treatment of mycobacterial disease
JPH10182618A (ja) 一酸化窒素合成酵素阻害剤

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20001104

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20040428

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20051122

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20060503

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20051122

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I