CN1201735C - 分枝杆菌抑制剂 - Google Patents

分枝杆菌抑制剂 Download PDF

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Publication number
CN1201735C
CN1201735C CNB99808283XA CN99808283A CN1201735C CN 1201735 C CN1201735 C CN 1201735C CN B99808283X A CNB99808283X A CN B99808283XA CN 99808283 A CN99808283 A CN 99808283A CN 1201735 C CN1201735 C CN 1201735C
Authority
CN
China
Prior art keywords
dione
nonyl
group
ethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB99808283XA
Other languages
English (en)
Chinese (zh)
Other versions
CN1308532A (zh
Inventor
M·巴尔加人内什
K·埃蒂拉
B·甘古利
R·亚纳基拉曼
P·卡乌
R·卡希帕拉
S·南丹
R·P·穆鲁加潘
N·拉马钱德兰
B·文卡特拉曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9802118A external-priority patent/SE9802118D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1308532A publication Critical patent/CN1308532A/zh
Application granted granted Critical
Publication of CN1201735C publication Critical patent/CN1201735C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
CNB99808283XA 1998-05-05 1999-05-03 分枝杆菌抑制剂 Expired - Fee Related CN1201735C (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN969/MAS/1998 1998-05-05
IN969MA1998 1998-05-05
IN969/MAS/98 1998-05-05
SE98021181 1998-06-15
SE9802118A SE9802118D0 (sv) 1998-06-15 1998-06-15 Mycobacterial inhibitors

Publications (2)

Publication Number Publication Date
CN1308532A CN1308532A (zh) 2001-08-15
CN1201735C true CN1201735C (zh) 2005-05-18

Family

ID=26324850

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB99808283XA Expired - Fee Related CN1201735C (zh) 1998-05-05 1999-05-03 分枝杆菌抑制剂

Country Status (14)

Country Link
US (1) US6476053B1 (cg-RX-API-DMAC10.html)
EP (1) EP1075261B1 (cg-RX-API-DMAC10.html)
JP (1) JP2002518324A (cg-RX-API-DMAC10.html)
KR (1) KR20010043322A (cg-RX-API-DMAC10.html)
CN (1) CN1201735C (cg-RX-API-DMAC10.html)
AT (1) ATE322898T1 (cg-RX-API-DMAC10.html)
AU (1) AU739140B2 (cg-RX-API-DMAC10.html)
BR (1) BR9910185A (cg-RX-API-DMAC10.html)
CA (1) CA2330667A1 (cg-RX-API-DMAC10.html)
DE (1) DE69930844T2 (cg-RX-API-DMAC10.html)
IL (1) IL139144A0 (cg-RX-API-DMAC10.html)
NO (1) NO20005548L (cg-RX-API-DMAC10.html)
NZ (1) NZ507620A (cg-RX-API-DMAC10.html)
WO (1) WO1999065483A1 (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107033060A (zh) * 2017-05-04 2017-08-11 浙江工业大学 一种n‑取代顺丁烯二酰亚胺类化合物及其制备与抗菌应用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2060259B1 (en) 2001-11-01 2010-01-20 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
KR20080034944A (ko) * 2005-08-19 2008-04-22 아스트라제네카 아베 결핵 치료용 피라졸론 유도체
GB0520368D0 (en) * 2005-10-06 2005-11-16 Univ Aston Antibacterial pyrrols
WO2010063617A1 (de) * 2008-12-04 2010-06-10 Basf Se Mischungen aus itaconsäure oder itaconsäurederivaten und primären aminen zur herstellung von 1,3- und 1,4-alkylmethylpyrrolidonen
PL3393530T3 (pl) * 2015-12-23 2022-12-05 Henkel Ag & Co. Kgaa Płyn do obróbki metali
CN111465611B (zh) * 2017-12-01 2024-10-11 古德T细胞有限公司 预防或治疗脱发的组合物
CN119569636B (zh) * 2024-10-22 2026-03-27 南京吉星生物技术开发有限公司 一种吡咯啉二酮类化合物及其制备方法和杀菌剂应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883342A (en) * 1973-04-13 1975-05-13 Akzona Inc Plant growth regulators

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107033060A (zh) * 2017-05-04 2017-08-11 浙江工业大学 一种n‑取代顺丁烯二酰亚胺类化合物及其制备与抗菌应用
CN107033060B (zh) * 2017-05-04 2020-01-14 浙江工业大学 一种n-取代顺丁烯二酰亚胺类化合物及其制备与抗菌应用

Also Published As

Publication number Publication date
NZ507620A (en) 2003-05-30
AU739140B2 (en) 2001-10-04
AU4304199A (en) 2000-01-05
DE69930844D1 (de) 2006-05-24
CA2330667A1 (en) 1999-12-23
IL139144A0 (en) 2001-11-25
NO20005548L (no) 2000-12-04
EP1075261B1 (en) 2006-04-12
CN1308532A (zh) 2001-08-15
NO20005548D0 (no) 2000-11-03
WO1999065483A1 (en) 1999-12-23
US6476053B1 (en) 2002-11-05
EP1075261A1 (en) 2001-02-14
DE69930844T2 (de) 2006-12-28
KR20010043322A (ko) 2001-05-25
ATE322898T1 (de) 2006-04-15
BR9910185A (pt) 2001-01-09
JP2002518324A (ja) 2002-06-25

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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
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GR01 Patent grant
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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050518

Termination date: 20100503