KR20010032800A - 신규 화합물 - Google Patents
신규 화합물 Download PDFInfo
- Publication number
- KR20010032800A KR20010032800A KR1020007006117A KR20007006117A KR20010032800A KR 20010032800 A KR20010032800 A KR 20010032800A KR 1020007006117 A KR1020007006117 A KR 1020007006117A KR 20007006117 A KR20007006117 A KR 20007006117A KR 20010032800 A KR20010032800 A KR 20010032800A
- Authority
- KR
- South Korea
- Prior art keywords
- pyridyl
- yloxy
- butyl
- dione
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9704546A SE9704546D0 (sv) | 1997-12-05 | 1997-12-05 | Novel compounds |
| SE9704546-2 | 1997-12-05 | ||
| PCT/SE1998/002190 WO1999029686A1 (en) | 1997-12-05 | 1998-12-01 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20010032800A true KR20010032800A (ko) | 2001-04-25 |
Family
ID=20409283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020007006117A KR20010032800A (ko) | 1997-12-05 | 1998-12-01 | 신규 화합물 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1037889A1 (no) |
| JP (1) | JP2001525406A (no) |
| KR (1) | KR20010032800A (no) |
| CN (1) | CN1284074A (no) |
| AU (1) | AU1791599A (no) |
| BR (1) | BR9813378A (no) |
| CA (1) | CA2312357A1 (no) |
| EE (1) | EE200000321A (no) |
| HU (1) | HUP0100731A3 (no) |
| IL (1) | IL136368A0 (no) |
| NO (1) | NO20002787L (no) |
| PL (1) | PL340837A1 (no) |
| SE (1) | SE9704546D0 (no) |
| SK (1) | SK8442000A3 (no) |
| TR (1) | TR200001544T2 (no) |
| WO (1) | WO1999029686A1 (no) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9901875D0 (sv) * | 1999-05-25 | 1999-05-25 | Astra Pharma Prod | Novel compounds |
| SE9904505D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Pharma Prod | Novel compounds |
| SE9904652D0 (sv) | 1999-12-17 | 1999-12-17 | Astra Pharma Prod | Novel Compounds |
| TWI258462B (en) | 1999-12-17 | 2006-07-21 | Astrazeneca Ab | Adamantane derivative compounds, process for preparing the same and pharmaceutical composition comprising the same |
| JP2002330787A (ja) * | 2000-10-21 | 2002-11-19 | Astrazeneca Ab | 化学物質 |
| PA8557501A1 (es) | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
| WO2003042190A1 (en) | 2001-11-12 | 2003-05-22 | Pfizer Products Inc. | N-alkyl-adamantyl derivatives as p2x7-receptor antagonists |
| PA8591801A1 (es) | 2002-12-31 | 2004-07-26 | Pfizer Prod Inc | Inhibidores benzamidicos del receptor p2x7. |
| US7071223B1 (en) | 2002-12-31 | 2006-07-04 | Pfizer, Inc. | Benzamide inhibitors of the P2X7 receptor |
| EP1626962B1 (en) | 2003-05-12 | 2007-02-28 | Pfizer Products Inc. | Benzamide inhibitors of the p2x7 receptor |
| GB0324498D0 (en) | 2003-07-21 | 2003-11-26 | Aventis Pharma Inc | Heterocyclic compounds as P2X7 ion channel blockers |
| MXPA06014022A (es) | 2004-06-29 | 2007-02-08 | Pfizer Prod Inc | Prcedimientos para preparar inhibidores de p2x7. |
| MX2008011919A (es) | 2006-03-16 | 2008-11-28 | Renovis Inc | Compuestos de bicicloheteroarilo como moduladores de p2x7 y usos de los mismos. |
| TWI464148B (zh) | 2006-03-16 | 2014-12-11 | Evotec Us Inc | 作為ｐ２ｘ7調節劑之雙環雜芳基化合物與其用途 |
| ES2569677T3 (es) | 2006-03-16 | 2016-05-12 | Second Genome, Inc. | Compuestos bicicloheteroarilo como moduladores de P2X7 y usos de los mismos |
| TW200813018A (en) | 2006-06-09 | 2008-03-16 | Astrazeneca Ab | Novel compounds |
| GB0613473D0 (en) * | 2006-07-06 | 2006-08-16 | Glaxo Group Ltd | Novel compounds |
| PL2049478T3 (pl) * | 2006-07-06 | 2012-09-28 | Glaxo Group Ltd | Podstawione N-fenylometylo 5-okso-prolino-2-amidy jako antagoniści receptora P2X7 oraz sposoby ich zastosowania |
| EP2124562B1 (en) | 2007-03-09 | 2016-04-20 | Second Genome, Inc. | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
| WO2008116845A1 (en) * | 2007-03-28 | 2008-10-02 | Glaxo Group Limited | Piperidinone carboxamide derivatives as p2x7 modulators |
| JP2010522710A (ja) * | 2007-03-29 | 2010-07-08 | グラクソ グループ リミテッド | Ｐ２ｘ７調節因子としてのオキサゾリジンおよびモルホリンカルボキサミド誘導体 |
| KR20090127435A (ko) * | 2007-04-03 | 2009-12-11 | 글락소 그룹 리미티드 | Ｐ2ｘ7 조절제로서의 이미다졸리딘 카르복스아미드 유도체 |
| US8119661B2 (en) | 2007-09-11 | 2012-02-21 | Astrazeneca Ab | Piperidine derivatives and their use as muscarinic receptor modulators |
| GB0803729D0 (en) * | 2008-02-29 | 2008-04-09 | Ge Healthcare Ltd | Imaging the central nervous system |
| BRPI0910034B1 (pt) | 2008-03-25 | 2022-02-08 | Affectis Pharmaceuticals Ag | Antagonistas do p2x7r e composições farmacêuticas que os compreendem |
| EP2243772B1 (en) | 2009-04-14 | 2012-01-18 | Affectis Pharmaceuticals AG | Novel P2X7R antagonists and their use |
| EP2322149A1 (en) | 2009-11-03 | 2011-05-18 | Universidad del Pais Vasco | Methods and compositions for the treatment of ischemia |
| AU2011252351A1 (en) | 2010-05-14 | 2012-10-11 | Affectis Pharmaceuticals Ag | Novel methods for the preparation of P2X7R antagonists |
| WO2012110190A1 (en) | 2011-02-17 | 2012-08-23 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
| WO2012163456A1 (en) | 2011-05-27 | 2012-12-06 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
| WO2012163792A1 (en) | 2011-05-27 | 2012-12-06 | Affectis Pharmaceuticals Ag | Novel p2x7r antagonists and their use |
| AU2018372136B2 (en) | 2017-11-21 | 2022-01-27 | Solventum Intellectual Properties Company | Oral plant-based-oil-in-water emulsions and methods of use |
| EP3727336A1 (en) | 2017-12-20 | 2020-10-28 | 3M Innovative Properties Company | Oral compositions and methods of use |
| JP7308835B2 (ja) | 2017-12-20 | 2023-07-14 | スリーエム イノベイティブ プロパティズ カンパニー | 口腔用組成物及び使用方法 |
-
1997
- 1997-12-05 SE SE9704546A patent/SE9704546D0/xx unknown
-
1998
- 1998-12-01 CN CN98813490A patent/CN1284074A/zh active Pending
- 1998-12-01 EP EP98962753A patent/EP1037889A1/en not_active Withdrawn
- 1998-12-01 JP JP2000524280A patent/JP2001525406A/ja not_active Withdrawn
- 1998-12-01 SK SK844-2000A patent/SK8442000A3/sk unknown
- 1998-12-01 EE EEP200000321A patent/EE200000321A/xx unknown
- 1998-12-01 CA CA002312357A patent/CA2312357A1/en not_active Abandoned
- 1998-12-01 HU HU0100731A patent/HUP0100731A3/hu unknown
- 1998-12-01 KR KR1020007006117A patent/KR20010032800A/ko not_active Application Discontinuation
- 1998-12-01 PL PL98340837A patent/PL340837A1/xx unknown
- 1998-12-01 AU AU17915/99A patent/AU1791599A/en not_active Abandoned
- 1998-12-01 IL IL13636898A patent/IL136368A0/xx unknown
- 1998-12-01 WO PCT/SE1998/002190 patent/WO1999029686A1/en not_active Application Discontinuation
- 1998-12-01 BR BR9813378-0A patent/BR9813378A/pt not_active Application Discontinuation
- 1998-12-01 TR TR2000/01544T patent/TR200001544T2/xx unknown
-
2000
- 2000-05-31 NO NO20002787A patent/NO20002787L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1791599A (en) | 1999-06-28 |
| SK8442000A3 (en) | 2001-01-18 |
| PL340837A1 (en) | 2001-02-26 |
| HUP0100731A3 (en) | 2002-08-28 |
| WO1999029686A1 (en) | 1999-06-17 |
| JP2001525406A (ja) | 2001-12-11 |
| EP1037889A1 (en) | 2000-09-27 |
| HUP0100731A2 (hu) | 2002-05-29 |
| IL136368A0 (en) | 2001-06-14 |
| SE9704546D0 (sv) | 1997-12-05 |
| NO20002787D0 (no) | 2000-05-31 |
| NO20002787L (no) | 2000-08-01 |
| BR9813378A (pt) | 2000-10-10 |
| CN1284074A (zh) | 2001-02-14 |
| TR200001544T2 (tr) | 2000-11-21 |
| EE200000321A (et) | 2001-08-15 |
| CA2312357A1 (en) | 1999-06-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |