KR20010031149A - 항소양 활성을 가진 화합물의 신규한 용도 - Google Patents

항소양 활성을 가진 화합물의 신규한 용도 Download PDF

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Publication number
KR20010031149A
KR20010031149A KR1020007004053A KR20007004053A KR20010031149A KR 20010031149 A KR20010031149 A KR 20010031149A KR 1020007004053 A KR1020007004053 A KR 1020007004053A KR 20007004053 A KR20007004053 A KR 20007004053A KR 20010031149 A KR20010031149 A KR 20010031149A
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KR
South Korea
Prior art keywords
xanthine
compound
cyclopropylmethyl
nitro
butyl
Prior art date
Application number
KR1020007004053A
Other languages
English (en)
Korean (ko)
Inventor
돈 이. 그리스월드
지그프리드 벤자민4세 크리스텐슨
Original Assignee
스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스
스미스클라인 비참 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스, 스미스클라인 비참 코포레이션 filed Critical 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스
Publication of KR20010031149A publication Critical patent/KR20010031149A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020007004053A 1997-10-17 1998-10-16 항소양 활성을 가진 화합물의 신규한 용도 KR20010031149A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6374697P 1997-10-17 1997-10-17
US60/063,746 1997-10-17
PCT/US1998/021886 WO1999020280A1 (en) 1997-10-17 1998-10-16 Novel use of compounds for anti-pruritic activity

Publications (1)

Publication Number Publication Date
KR20010031149A true KR20010031149A (ko) 2001-04-16

Family

ID=22051225

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007004053A KR20010031149A (ko) 1997-10-17 1998-10-16 항소양 활성을 가진 화합물의 신규한 용도

Country Status (18)

Country Link
EP (1) EP1030666A4 (xx)
JP (1) JP2001520196A (xx)
KR (1) KR20010031149A (xx)
CN (1) CN1306426A (xx)
AR (1) AR015966A1 (xx)
AU (1) AU740875B2 (xx)
BR (1) BR9814080A (xx)
CA (1) CA2306985A1 (xx)
CO (1) CO4810374A1 (xx)
CZ (1) CZ20001376A3 (xx)
HU (1) HUP0003792A3 (xx)
IL (1) IL135581A0 (xx)
NO (1) NO20001847D0 (xx)
NZ (1) NZ503551A (xx)
PL (1) PL341062A1 (xx)
TR (1) TR200001040T2 (xx)
WO (1) WO1999020280A1 (xx)
ZA (1) ZA989450B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7250518B2 (en) 2001-01-31 2007-07-31 Pfizer Inc. Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
CA2436535A1 (en) 2001-01-31 2002-08-08 Prizer Products Inc. Nicotinamide biaryl derivatives useful as inhibitors of pde4 isozymes
EE200300362A (et) 2001-01-31 2003-12-15 Pfizer Products Inc. PDE4 isosüümide inhibiitoritena kasutatavad tiasolüül-, oksasolüül-, pürrolüül- ja imidasolüülhappeamiidi derivaadid
HUP0302891A2 (hu) 2001-01-31 2003-12-29 Pfizer Products Inc. PDE4 izoenzimek inhibitoraiként alkalmazható éterszármazékok, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények
US20030175314A1 (en) * 2001-11-19 2003-09-18 Didriksen Erik Johannes Pharmaceutical composition for dermal application
EP1647274A4 (en) * 2003-07-17 2008-12-10 Ono Pharmaceutical Co REMEDY AGAINST PRURIT COMPRISING A PIPERIDINE DERIVATIVE AS AN ACTIVE INGREDIENT
JP2005187458A (ja) * 2003-12-04 2005-07-14 Santen Pharmaceut Co Ltd シロミラストまたはその塩を有効成分とする掻痒治療剤
WO2005053672A1 (ja) * 2003-12-04 2005-06-16 Santen Pharmaceutical Co., Ltd. シロミラストまたはその塩を有効成分とする掻痒治療剤
WO2005077950A2 (en) 2004-02-14 2005-08-25 Smithkline Beecham Corporation Medicaments with hm74a receptor activity
JP2008137892A (ja) * 2005-03-04 2008-06-19 Eisai Co Ltd 止痒剤
BRPI0614270A2 (pt) 2005-08-10 2011-03-22 Smithkline Beecham Corp derivados xantina como seletivos agonistas de ha74a
TWI404709B (zh) * 2006-02-21 2013-08-11 Eisai R&D Man Co Ltd 4- (3-benzamidophenyl) -6,7-dimethoxy-2-methylamine quinazoline derivatives
EP1992622B1 (en) * 2006-02-21 2011-07-27 Eisai R&D Management Co., Ltd. 4-(3-benzoylaminophenyl)-6,7-dimethoxy-2- methylaminoquinazoline derivative
EP2123641A4 (en) 2007-02-16 2011-06-22 Eisai R&D Man Co Ltd CRYSTAL, AMORPHOUS FORM AND METHYL N-Ý3- (6,7-DIMETHOXY-2-METHYLAMINOQUINAZOLINE-4-YL) PHENYLENE TEREPHTALIC ACID SALT
CN102336717B (zh) 2007-08-17 2013-09-18 卫材R&D管理有限公司 喹唑啉衍生物
US8513269B2 (en) 2007-08-17 2013-08-20 Eisai R&D Management Co., Ltd. Preparation for external use
US20140121240A1 (en) 2011-06-28 2014-05-01 Maruho Co., Ltd. Novel pharmaceutical composition
EA034139B1 (ru) 2015-01-30 2020-01-09 Шаньтонь Фарма Ко., Лтд. Профилактика или лечение мочекислых или подагрических заболеваний

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0563168B1 (en) * 1990-12-21 2000-07-05 Beecham Group Plc Xanthine derivatives
ATE224386T1 (de) * 1996-03-26 2002-10-15 Altana Pharma Ag Neue in 6-position substituierte phenanthridine
ES2187775T3 (es) * 1996-05-15 2003-06-16 Altana Pharma Ag Imidazopiridinas.
DE69817548T2 (de) * 1997-03-07 2004-06-17 Altana Pharma Ag Tetrazole derivate
PL336464A1 (en) * 1997-03-18 2000-06-19 Basf Ag Method of and compositions for modulating reactivity in respect to corticosteroids i
WO1998055481A1 (en) * 1997-06-03 1998-12-10 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine

Also Published As

Publication number Publication date
IL135581A0 (en) 2001-05-20
ZA989450B (en) 1999-04-19
AU740875B2 (en) 2001-11-15
TR200001040T2 (tr) 2001-01-22
CA2306985A1 (en) 1999-04-29
AU1093899A (en) 1999-05-10
WO1999020280A1 (en) 1999-04-29
CZ20001376A3 (cs) 2002-06-12
NZ503551A (en) 2002-05-31
CN1306426A (zh) 2001-08-01
HUP0003792A3 (en) 2001-12-28
EP1030666A4 (en) 2002-10-16
BR9814080A (pt) 2000-09-26
HUP0003792A2 (hu) 2001-10-28
CO4810374A1 (es) 1999-06-30
NO20001847L (no) 2000-04-10
NO20001847D0 (no) 2000-04-10
AR015966A1 (es) 2001-05-30
EP1030666A1 (en) 2000-08-30
PL341062A1 (en) 2001-03-26
JP2001520196A (ja) 2001-10-30

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