KR19990063834A - 단형 케모킨 베타-8 - Google Patents

단형 케모킨 베타-8 Download PDF

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Publication number
KR19990063834A
KR19990063834A KR1019980702304A KR19980702304A KR19990063834A KR 19990063834 A KR19990063834 A KR 19990063834A KR 1019980702304 A KR1019980702304 A KR 1019980702304A KR 19980702304 A KR19980702304 A KR 19980702304A KR 19990063834 A KR19990063834 A KR 19990063834A
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KR
South Korea
Prior art keywords
polypeptide
ckβ
cells
polypeptides
seq
Prior art date
Application number
KR1019980702304A
Other languages
English (en)
Korean (ko)
Inventor
화이트 존
아펠바움 에드워드
오샤네시 다니엘
알란 폰월드 제임스
오도넬 케빈
Original Assignee
스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스
스미스클라인 비참 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스, 스미스클라인 비참 코포레이션 filed Critical 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스
Publication of KR19990063834A publication Critical patent/KR19990063834A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
KR1019980702304A 1995-09-29 1996-09-27 단형 케모킨 베타-8 KR19990063834A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US451795P 1995-09-29 1995-09-29
US60/004517 1995-09-29
PCT/US1996/015592 WO1997012041A1 (en) 1995-09-29 1996-09-27 SHORT FORMS OF CHEMOKINE β-8

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020017012319A Division KR20030096447A (ko) 1995-09-29 1996-09-27 단축형 케모킨 베타-8

Publications (1)

Publication Number Publication Date
KR19990063834A true KR19990063834A (ko) 1999-07-26

Family

ID=21711157

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019980702304A KR19990063834A (ko) 1995-09-29 1996-09-27 단형 케모킨 베타-8
KR1020017012319A KR20030096447A (ko) 1995-09-29 1996-09-27 단축형 케모킨 베타-8

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020017012319A KR20030096447A (ko) 1995-09-29 1996-09-27 단축형 케모킨 베타-8

Country Status (16)

Country Link
EP (1) EP0859842A4 (xx)
JP (1) JPH11512610A (xx)
KR (2) KR19990063834A (xx)
CN (2) CN1198186A (xx)
AU (1) AU711573B2 (xx)
BG (1) BG102413A (xx)
BR (1) BR9610671A (xx)
CZ (1) CZ92198A3 (xx)
EA (1) EA199800352A1 (xx)
HU (1) HUP9802699A3 (xx)
NO (1) NO981387L (xx)
NZ (1) NZ320932A (xx)
PL (1) PL326080A1 (xx)
TR (1) TR199800575T1 (xx)
WO (1) WO1997012041A1 (xx)
ZA (1) ZA968204B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001606A (en) * 1994-03-08 1999-12-14 Human Genome Sciences, Inc. Polynucleotides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) and polypeptides encoded thereby
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
JP2001500382A (ja) * 1996-09-30 2001-01-16 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド 骨髄前駆体阻害因子―１（ｍｐｉｆ―１）、単球コロニー阻害因子（ｍ―ｃｉｆ）、およびマクロファージ阻害因子―４（ｍｉｐ―４）で疾患状態を処置するための治療組成物および方法
KR19990042713A (ko) * 1997-11-27 1999-06-15 허일섭 사람에서 분리한 c 6 베타-케모카인 lkn-1의 cdna 및 재조합 lkn-1의 제조방법
AU2505601A (en) * 1999-11-15 2001-05-30 Wolf-Georg Forssmann Novel use of hcc-2
US20030215460A1 (en) * 2002-05-07 2003-11-20 Schall Thomas J. Methods and compositions for inducing an immune response

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ271756A (en) * 1993-12-22 1998-02-26 Human Genome Sciences Inc Human macrophage inflammatory proteins and coding sequences, their production and use
EP0871672A4 (en) * 1995-05-05 1999-05-12 Human Genome Sciences Inc CHIMIOKINE BETA-8, CHIMIOKINE BETA-1 AND PROTEIN 4 INFLAMMATORY FROM HUMAN ORIGINAL MACROPHAGES
ZA968897B (en) * 1995-10-24 1998-07-14 Smithkline Beecham Corp Novel chemokine for mobilizing stem cells
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10

Also Published As

Publication number Publication date
TR199800575T1 (en) 1998-06-22
HUP9802699A3 (en) 2000-09-28
CZ92198A3 (cs) 1998-07-15
AU7379096A (en) 1997-04-17
MX9802380A (es) 1998-08-30
EP0859842A4 (en) 1999-02-24
ZA968204B (en) 1997-04-09
KR20030096447A (ko) 2003-12-31
EP0859842A1 (en) 1998-08-26
HUP9802699A2 (hu) 1999-03-29
NO981387D0 (no) 1998-03-26
BR9610671A (pt) 1999-07-06
CN1198186A (zh) 1998-11-04
CN1405180A (zh) 2003-03-26
WO1997012041A1 (en) 1997-04-03
JPH11512610A (ja) 1999-11-02
BG102413A (bg) 1999-04-30
PL326080A1 (en) 1998-08-17
EA199800352A1 (ru) 1998-12-24
AU711573B2 (en) 1999-10-14
NO981387L (no) 1998-05-29
NZ320932A (en) 2000-01-28

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