KR102799152B1 - 프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물 - Google Patents

프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물 Download PDF

Info

Publication number
KR102799152B1
KR102799152B1 KR1020197034011A KR20197034011A KR102799152B1 KR 102799152 B1 KR102799152 B1 KR 102799152B1 KR 1020197034011 A KR1020197034011 A KR 1020197034011A KR 20197034011 A KR20197034011 A KR 20197034011A KR 102799152 B1 KR102799152 B1 KR 102799152B1
Authority
KR
South Korea
Prior art keywords
sequence
acnes
ala
gly
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020197034011A
Other languages
English (en)
Korean (ko)
Other versions
KR20190135054A (ko
Inventor
유그 바마
프루옌 낸시 반
Original Assignee
파이 테라퓨틱스, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 파이 테라퓨틱스, 인크. filed Critical 파이 테라퓨틱스, 인크.
Priority to KR1020257012416A priority Critical patent/KR20250054134A/ko
Publication of KR20190135054A publication Critical patent/KR20190135054A/ko
Application granted granted Critical
Publication of KR102799152B1 publication Critical patent/KR102799152B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/327Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • A61K38/446Superoxide dismutase (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/06Emulsions
    • A61K8/062Oil-in-water emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/06Emulsions
    • A61K8/064Water-in-oil emulsions, e.g. Water-in-silicone emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22Peroxides; Oxygen; Ozone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23Sulfur; Selenium; Tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052Beta-N-acetylhexosaminidase (3.2.1.52)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10321Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y105/00Oxidoreductases acting on the CH-NH group of donors (1.5)
    • C12Y105/01Oxidoreductases acting on the CH-NH group of donors (1.5) with NAD+ or NADP+ as acceptor (1.5.1)
    • C12Y105/01001Pyrroline-2-carboxylate reductase (1.5.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y111/00Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/01Peroxidases (1.11.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21062Subtilisin (3.4.21.62)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21064Peptidase K (3.4.21.64)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020197034011A 2017-04-21 2018-04-20 프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물 Active KR102799152B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257012416A KR20250054134A (ko) 2017-04-21 2018-04-20 프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762488326P 2017-04-21 2017-04-21
US62/488,326 2017-04-21
PCT/US2018/028556 WO2018195415A1 (en) 2017-04-21 2018-04-20 Compositions comprising propionibacterium acnes bacteriophages for treating acne

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020257012416A Division KR20250054134A (ko) 2017-04-21 2018-04-20 프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물

Publications (2)

Publication Number Publication Date
KR20190135054A KR20190135054A (ko) 2019-12-05
KR102799152B1 true KR102799152B1 (ko) 2025-04-23

Family

ID=63857016

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020197034011A Active KR102799152B1 (ko) 2017-04-21 2018-04-20 프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물
KR1020257012416A Pending KR20250054134A (ko) 2017-04-21 2018-04-20 프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020257012416A Pending KR20250054134A (ko) 2017-04-21 2018-04-20 프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물

Country Status (8)

Country Link
US (3) US20210338569A1 (enExample)
EP (1) EP3612200A4 (enExample)
JP (2) JP7595459B2 (enExample)
KR (2) KR102799152B1 (enExample)
CN (1) CN110799203A (enExample)
AU (1) AU2018255972B2 (enExample)
CA (1) CA3060415A1 (enExample)
WO (1) WO2018195415A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017254684A1 (en) 2016-04-21 2018-12-06 Weiss Bioscience, Inc. Compositions and methods for treatment of skin disorders
JP7595459B2 (ja) 2017-04-21 2024-12-06 ピー・エイチ・アイ・セラピューティクス・インコーポレイテッド ざ瘡を治療するためのプロピオニバクテリウムアクネス(Propionibacterium acnes)バクテリオファージを含む組成物
US20210177920A1 (en) * 2017-12-05 2021-06-17 Biomx Ltd. Bacteriophage treatment for acne and biofilms
WO2020104216A1 (en) * 2018-11-19 2020-05-28 Unilever N.V. An antimicrobial composition for selectively inhibiting growth of p. acnes bacteria
KR20210033627A (ko) * 2019-09-19 2021-03-29 성균관대학교산학협력단 레조르시놀 또는 페닐에틸레조르시놀을 포함하는 공기오염물질에 의해 유발되는 피부 질환 예방, 치료, 또는 개선용 조성물
CN115813869A (zh) * 2022-12-15 2023-03-21 深圳市奥极因科技有限公司 一种感知进食状态智能给药的重组菌含片
WO2025024918A1 (en) * 2023-07-28 2025-02-06 Kane Biotech Inc. Composition, methods, and uses thereof for acne prevention, reduction, and treatment
CO2023015253A1 (es) * 2023-11-10 2024-02-15 Univ Los Andes Fago funcionalizado para tratamiento de acné

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US6117433A (en) * 1996-01-31 2000-09-12 Dsm N.V. Use of compositions comprising stabilized biologically effective compounds
US6034506A (en) 1998-01-16 2000-03-07 Space Systems/Loral, Inc. Lithium ion satellite battery charge control circuit
US6235033B1 (en) 2000-04-19 2001-05-22 Synthes (Usa) Bone fixation assembly
EP1907534B2 (en) 2005-07-12 2024-04-10 Micreos B.V. Bacteriophage and their uses
JP2008297241A (ja) * 2007-05-31 2008-12-11 Fujifilm Corp ニキビ用皮膚外用剤
ES2569218T3 (es) * 2008-12-17 2016-05-09 Ei, Inc. Base de polvo para tratamiento del acné
BR112012003792B1 (pt) * 2009-08-21 2020-05-19 Novan Inc composição tópica, e, uso da composição tópica
KR20120115920A (ko) * 2011-04-11 2012-10-19 신라대학교 산학협력단 여드름 치료, 개선 또는 예방용 조성물
EP3692999A1 (en) 2012-03-17 2020-08-12 The Regents of the University of California Fast diagnosis and personalized treatments for acne
US20160338979A1 (en) * 2014-01-10 2016-11-24 The Regents Of The University Of California Skin probiotic
GB201402139D0 (en) * 2014-02-07 2014-03-26 Fixed Phage Ltd Treatment of topical and systemic bacterial infections
KR101689033B1 (ko) * 2014-06-10 2016-12-22 경북대학교 산학협력단 여드름균을 사멸시키는 여드름균 특이적 박테리오파지
WO2016130024A1 (en) * 2015-02-13 2016-08-18 Supreme Biotechnologies Limited Endolysin expression platform
US12043847B2 (en) * 2016-05-15 2024-07-23 The Regents Of The University Of California Compositions and methods for treating acne
JP7595459B2 (ja) 2017-04-21 2024-12-06 ピー・エイチ・アイ・セラピューティクス・インコーポレイテッド ざ瘡を治療するためのプロピオニバクテリウムアクネス(Propionibacterium acnes)バクテリオファージを含む組成物
US20210177920A1 (en) * 2017-12-05 2021-06-17 Biomx Ltd. Bacteriophage treatment for acne and biofilms

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DRUG FACTS, DAILYMED, NDC Code: 59779-813-68(2010.07.10.) 1부.*
Front. Microbiol. (2017) 8:164(2017.02.08.) 1부.*
NCBI GenBank Accession No.DQ431235.1(2007.05.24.) 1부.*
Proceedings of the National Academy of Sciences, 104(27), 11197-11202(2007.07.03.) 1부.*

Also Published As

Publication number Publication date
US20210338569A1 (en) 2021-11-04
KR20250054134A (ko) 2025-04-22
WO2018195415A1 (en) 2018-10-25
CN110799203A (zh) 2020-02-14
KR20190135054A (ko) 2019-12-05
JP7801389B2 (ja) 2026-01-16
EP3612200A4 (en) 2020-12-30
JP2024099592A (ja) 2024-07-25
AU2018255972A1 (en) 2019-10-31
CA3060415A1 (en) 2018-10-25
JP2020517735A (ja) 2020-06-18
US11903984B1 (en) 2024-02-20
US20240189220A1 (en) 2024-06-13
EP3612200A1 (en) 2020-02-26
JP7595459B2 (ja) 2024-12-06
AU2018255972B2 (en) 2024-11-21
US20240066079A1 (en) 2024-02-29

Similar Documents

Publication Publication Date Title
KR102799152B1 (ko) 프로피오니박테리움 아크네스 박테리오파지를 포함하는 여드름 치료용 조성물
Liu et al. Identification of two depolymerases from phage IME205 and their antivirulent functions on K47 capsule of Klebsiella pneumoniae
Kešnerová et al. Bartonella apis sp. nov., a honey bee gut symbiont of the class Alphaproteobacteria
Donnarumma et al. Lactobacillus crispatus L1: high cell density cultivation and exopolysaccharide structure characterization to highlight potentially beneficial effects against vaginal pathogens
Barnes et al. γ-Glutamyl transpeptidase has a role in the persistent colonization of the avian gut by Campylobacter jejuni
Villageliu et al. The role of bacterial membrane vesicles in human health and disease
JP7460531B2 (ja) 微生物感染を防ぐための方法および組成物
JP2022058682A (ja) グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ
Machuca et al. Isolation of a novel bacteriophage specific for the periodontal pathogen Fusobacterium nucleatum
Seal Characterization of bacteriophages virulent for Clostridium perfringens and identification of phage lytic enzymes as alternatives to antibiotics for potential control of the bacterium
HK1244503A1 (zh) 用於革兰氏阳性菌检测和治疗的链球菌属细菌噬菌体溶素
JP2025026484A (ja) 新規ガードネレラエンドリシンとその使用
US20140179594A1 (en) Streptococcus bacteriophage lysins for treatment of gram positive bacteria in companion animals and livestock
Wang et al. A novel lysin Ply1228 provides efficient protection against Streptococcus suis type 2 infection in a murine bacteremia model
EP2465926A1 (en) Pseudomonas aeruginosa Bacteriophage and uses thereof
Zahir et al. Aerococcus sp. with an antimycobacterial effect
KR20250167084A (ko) 습진을 포함한 피부 질환 및 병태의 치료를 위한 조성물 및 방법
CN119736279A (zh) 抗微生物内溶素多肽、组合物和制剂
RU2820886C2 (ru) Новые эндолизины гарднереллы и их применение
Górski Prospects of Phage Application in the Treatment of Acne Caused by
Kante et al. In vitro reconstitution of the M. tb proteasome core particle reveals conserved aspects of bacterial proteasome assembly
Cui et al. Next-generation antimicrobials: A review of phage lysins as precision weapons against drug-resistant pathogens
Antonova et al. Broad Bactericidal Activity of the Myoviridae Bacteriophage Lysins LysAm24, LysECD7, and LysSi3
Gyanwali et al. Enhanced Host Range and Reduction of Biofilm by Synergistic Effect of Phage Cocktails Isolated from Rivers of Kathmandu, Nepal
Augsburg Exploring the skin microbiome in atopic dermatitis pathogenesis and disease modification

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20191118

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20210420

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20230526

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20240521

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20230526

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

AMND Amendment
PX0901 Re-examination

Patent event code: PX09012R01I

Patent event date: 20240822

Comment text: Amendment to Specification, etc.

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20240906

Patent event code: PE09021S01D

PX0701 Decision of registration after re-examination

Patent event date: 20250116

Comment text: Decision to Grant Registration

Patent event code: PX07013S01D

X701 Decision to grant (after re-examination)
A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20250416

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20250417

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20250417

End annual number: 3

Start annual number: 1

PG1601 Publication of registration