KR102662461B1 - 비염증성 병변의 치료 - Google Patents

비염증성 병변의 치료 Download PDF

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Publication number
KR102662461B1
KR102662461B1 KR1020207003934A KR20207003934A KR102662461B1 KR 102662461 B1 KR102662461 B1 KR 102662461B1 KR 1020207003934 A KR1020207003934 A KR 1020207003934A KR 20207003934 A KR20207003934 A KR 20207003934A KR 102662461 B1 KR102662461 B1 KR 102662461B1
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South Korea
Prior art keywords
methyl
inflammatory lesions
lesions
effective amount
treatment
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Korean (ko)
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KR20200031126A (ko
Inventor
데이비드 버크
알렉산드레 카우코프
빌마 스니우킨
카스텐 슈미츠
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알미랄 엘엘씨
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020207003934A 2017-07-21 2018-07-20 비염증성 병변의 치료 Active KR102662461B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762535572P 2017-07-21 2017-07-21
US62/535,572 2017-07-21
PCT/IB2018/000938 WO2019016609A1 (en) 2017-07-21 2018-07-20 TREATMENT OF NON-INFLAMMATORY LESIONS

Publications (2)

Publication Number Publication Date
KR20200031126A KR20200031126A (ko) 2020-03-23
KR102662461B1 true KR102662461B1 (ko) 2024-04-30

Family

ID=63713912

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207003934A Active KR102662461B1 (ko) 2017-07-21 2018-07-20 비염증성 병변의 치료

Country Status (13)

Country Link
US (1) US20200222432A1 (https=)
EP (1) EP3654988B1 (https=)
JP (1) JP2020527607A (https=)
KR (1) KR102662461B1 (https=)
CN (1) CN111343991A (https=)
AU (1) AU2018303807B2 (https=)
BR (1) BR112020000968A2 (https=)
CA (1) CA3070663A1 (https=)
ES (1) ES2962380T3 (https=)
IL (1) IL272124A (https=)
MA (1) MA49641A (https=)
MX (1) MX2020000816A (https=)
WO (1) WO2019016609A1 (https=)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012155146A1 (en) * 2011-05-12 2012-11-15 Paratek Pharmaceuticals, Inc. Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
US2980584A (en) 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US3062717A (en) 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3165531A (en) 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3454697A (en) 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (https=) 1966-05-31 1967-12-01
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
EP1383508B1 (en) * 2001-04-05 2006-06-21 Collagenex Pharmaceuticals, Inc. Doxycycline for the treatment of acne
US7704959B2 (en) * 2006-10-03 2010-04-27 Dow Pharmaceutical Sciences Azithromycin for the treatment of nodular acne
CA2892739A1 (en) * 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
WO2008079339A2 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
CA2724412A1 (en) * 2008-05-21 2009-11-26 Galderma Research & Development Maintenance therapy regimen for treating acne
CN102056481A (zh) * 2008-06-05 2011-05-11 陶氏制药科学公司 包含低浓度的在水和水混溶性有机溶剂中的悬浮液形式的过氧苯甲酰的局部药物制剂
JP2013500984A (ja) * 2009-07-30 2013-01-10 アラーガン、インコーポレイテッド ダプソンとアダパレンの組み合わせ
US20140121188A1 (en) * 2009-10-02 2014-05-01 Foamix Ltd. Compositions for the improved treatment of acne and related disorders
IL225246A0 (en) * 2012-03-15 2013-06-27 Meir Eini Methods for speeding up the restoration of skin normality and for treatment of impetigo
GB201615693D0 (en) * 2016-09-15 2016-11-02 Combinatorx Infection Ltd Combinations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012155146A1 (en) * 2011-05-12 2012-11-15 Paratek Pharmaceuticals, Inc. Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same

Also Published As

Publication number Publication date
AU2018303807B2 (en) 2023-08-24
CA3070663A1 (en) 2019-01-24
IL272124A (en) 2020-03-31
WO2019016609A1 (en) 2019-01-24
KR20200031126A (ko) 2020-03-23
EP3654988A1 (en) 2020-05-27
BR112020000968A2 (pt) 2020-07-14
ES2962380T3 (es) 2024-03-18
CN111343991A (zh) 2020-06-26
AU2018303807A1 (en) 2020-02-13
MA49641A (fr) 2021-06-02
US20200222432A1 (en) 2020-07-16
JP2020527607A (ja) 2020-09-10
MX2020000816A (es) 2020-08-17
EP3654988B1 (en) 2023-09-06

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