KR102662461B1 - 비염증성 병변의 치료 - Google Patents

비염증성 병변의 치료 Download PDF

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Publication number
KR102662461B1
KR102662461B1 KR1020207003934A KR20207003934A KR102662461B1 KR 102662461 B1 KR102662461 B1 KR 102662461B1 KR 1020207003934 A KR1020207003934 A KR 1020207003934A KR 20207003934 A KR20207003934 A KR 20207003934A KR 102662461 B1 KR102662461 B1 KR 102662461B1
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South Korea
Prior art keywords
methyl
inflammatory lesions
lesions
effective amount
treatment
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English (en)
Korean (ko)
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KR20200031126A (ko
Inventor
데이비드 버크
알렉산드레 카우코프
빌마 스니우킨
카스텐 슈미츠
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알미랄 엘엘씨
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020207003934A 2017-07-21 2018-07-20 비염증성 병변의 치료 Active KR102662461B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762535572P 2017-07-21 2017-07-21
US62/535,572 2017-07-21
PCT/IB2018/000938 WO2019016609A1 (en) 2017-07-21 2018-07-20 TREATMENT OF NON-INFLAMMATORY LESIONS

Publications (2)

Publication Number Publication Date
KR20200031126A KR20200031126A (ko) 2020-03-23
KR102662461B1 true KR102662461B1 (ko) 2024-04-30

Family

ID=63713912

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207003934A Active KR102662461B1 (ko) 2017-07-21 2018-07-20 비염증성 병변의 치료

Country Status (13)

Country Link
US (1) US20200222432A1 (https=)
EP (1) EP3654988B1 (https=)
JP (1) JP2020527607A (https=)
KR (1) KR102662461B1 (https=)
CN (1) CN111343991A (https=)
AU (1) AU2018303807B2 (https=)
BR (1) BR112020000968A2 (https=)
CA (1) CA3070663A1 (https=)
ES (1) ES2962380T3 (https=)
IL (1) IL272124A (https=)
MA (1) MA49641A (https=)
MX (1) MX2020000816A (https=)
WO (1) WO2019016609A1 (https=)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012155146A1 (en) * 2011-05-12 2012-11-15 Paratek Pharmaceuticals, Inc. Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
US2980584A (en) 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US3062717A (en) 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3165531A (en) 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3454697A (en) 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (https=) 1966-05-31 1967-12-01
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
AU2002303250B2 (en) * 2001-04-05 2006-05-25 Collagenex Pharmaceuticals, Inc. Methods of treating acne
US7704959B2 (en) * 2006-10-03 2010-04-27 Dow Pharmaceutical Sciences Azithromycin for the treatment of nodular acne
PL2109602T3 (pl) 2006-12-21 2014-09-30 Paratek Pharm Innc Pochodne tetracyliny do leczenia zakażeń bakteryjnych, wirusowych i pasożytniczych
PT2120963T (pt) 2006-12-21 2018-12-17 Paratek Pharm Innc Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele
EP2280733A1 (en) * 2008-05-21 2011-02-09 Galderma Research & Development Maintenance therapy regimen for treating acne
CA2723029C (en) * 2008-06-05 2016-07-19 Dow Pharmaceutical Sciences, Inc. Topical pharmaceutical formulations containing a low concentration of benzoyl peroxide in suspension in water and a water-miscible organic solvent
CA2769640A1 (en) * 2009-07-30 2011-02-03 Allergan, Inc. Combination of dapsone with adapalene
US20140121188A1 (en) * 2009-10-02 2014-05-01 Foamix Ltd. Compositions for the improved treatment of acne and related disorders
IL225239A0 (en) * 2012-03-15 2013-06-27 Meir Eini Compounds for the treatment of acne and related diseases
GB201615693D0 (en) * 2016-09-15 2016-11-02 Combinatorx Infection Ltd Combinations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012155146A1 (en) * 2011-05-12 2012-11-15 Paratek Pharmaceuticals, Inc. Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same

Also Published As

Publication number Publication date
EP3654988B1 (en) 2023-09-06
US20200222432A1 (en) 2020-07-16
JP2020527607A (ja) 2020-09-10
KR20200031126A (ko) 2020-03-23
CN111343991A (zh) 2020-06-26
EP3654988A1 (en) 2020-05-27
AU2018303807B2 (en) 2023-08-24
CA3070663A1 (en) 2019-01-24
MX2020000816A (es) 2020-08-17
MA49641A (fr) 2021-06-02
AU2018303807A1 (en) 2020-02-13
IL272124A (en) 2020-03-31
WO2019016609A1 (en) 2019-01-24
ES2962380T3 (es) 2024-03-18
BR112020000968A2 (pt) 2020-07-14

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