JP2020527607A5 - - Google Patents
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- Publication number
- JP2020527607A5 JP2020527607A5 JP2020524697A JP2020524697A JP2020527607A5 JP 2020527607 A5 JP2020527607 A5 JP 2020527607A5 JP 2020524697 A JP2020524697 A JP 2020524697A JP 2020524697 A JP2020524697 A JP 2020524697A JP 2020527607 A5 JP2020527607 A5 JP 2020527607A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament according
- therapeutically effective
- effective amount
- weeks
- day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims description 21
- 206010000496 acne Diseases 0.000 claims description 20
- 230000003902 lesion Effects 0.000 claims description 17
- 230000002757 inflammatory effect Effects 0.000 claims description 16
- 150000003839 salts Chemical class 0.000 claims description 14
- 208000002874 Acne Vulgaris Diseases 0.000 claims description 12
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 8
- -1 methoxy (methyl) amino Chemical group 0.000 claims description 5
- 208000024891 symptom Diseases 0.000 claims description 5
- 239000006186 oral dosage form Substances 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 3
- 230000001815 facial effect Effects 0.000 claims description 3
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 1
- 238000000034 method Methods 0.000 description 13
- 239000000902 placebo Substances 0.000 description 2
- 229940068196 placebo Drugs 0.000 description 2
- ZOGWILCBTHYRBE-UHFFFAOYSA-N OC1=C(C(C2C=C3C(C4=CC=CC(=C4CC3CC2C1)CN(C)OC)=O)=O)C(=O)N Chemical compound OC1=C(C(C2C=C3C(C4=CC=CC(=C4CC3CC2C1)CN(C)OC)=O)=O)C(=O)N ZOGWILCBTHYRBE-UHFFFAOYSA-N 0.000 description 1
- PQJQFLNBMSCUSH-SBAJWEJLSA-N chembl2364632 Chemical compound O=C1C2=C(O)[C@@](C(C(C(N)=O)=C(O)[C@H]3N(C)C)=O)(O)[C@H]3C[C@@H]2CC2=C1C(O)=CC=C2CN(C)OC PQJQFLNBMSCUSH-SBAJWEJLSA-N 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762535572P | 2017-07-21 | 2017-07-21 | |
| US62/535,572 | 2017-07-21 | ||
| PCT/IB2018/000938 WO2019016609A1 (en) | 2017-07-21 | 2018-07-20 | TREATMENT OF NON-INFLAMMATORY LESIONS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020527607A JP2020527607A (ja) | 2020-09-10 |
| JP2020527607A5 true JP2020527607A5 (https=) | 2021-02-25 |
Family
ID=63713912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020524697A Pending JP2020527607A (ja) | 2017-07-21 | 2018-07-20 | 非炎症性病変の処置 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20200222432A1 (https=) |
| EP (1) | EP3654988B1 (https=) |
| JP (1) | JP2020527607A (https=) |
| KR (1) | KR102662461B1 (https=) |
| CN (1) | CN111343991A (https=) |
| AU (1) | AU2018303807B2 (https=) |
| BR (1) | BR112020000968A2 (https=) |
| CA (1) | CA3070663A1 (https=) |
| ES (1) | ES2962380T3 (https=) |
| IL (1) | IL272124A (https=) |
| MA (1) | MA49641A (https=) |
| MX (1) | MX2020000816A (https=) |
| WO (1) | WO2019016609A1 (https=) |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2990331A (en) | 1956-11-23 | 1961-06-27 | Pfizer & Co C | Stable solutions of salts of tetracyclines for parenteral administration |
| US2980584A (en) | 1957-10-29 | 1961-04-18 | Pfizer & Co C | Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation |
| US3062717A (en) | 1958-12-11 | 1962-11-06 | Pfizer & Co C | Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation |
| US3165531A (en) | 1962-03-08 | 1965-01-12 | Pfizer & Co C | 13-substituted-6-deoxytetracyclines and process utilizing the same |
| US3454697A (en) | 1965-06-08 | 1969-07-08 | American Cyanamid Co | Tetracycline antibiotic compositions for oral use |
| NL6607516A (https=) | 1966-05-31 | 1967-12-01 | ||
| DE1767891C3 (de) | 1968-06-28 | 1980-10-30 | Pfizer | Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat |
| US3957980A (en) | 1972-10-26 | 1976-05-18 | Pfizer Inc. | Doxycycline parenteral compositions |
| DE2442829A1 (de) | 1974-09-06 | 1976-03-18 | Merck Patent Gmbh | Tetracyclische verbindungen und verfahren zu ihrer herstellung |
| US4018889A (en) | 1976-01-02 | 1977-04-19 | Pfizer Inc. | Oxytetracycline compositions |
| US4126680A (en) | 1977-04-27 | 1978-11-21 | Pfizer Inc. | Tetracycline antibiotic compositions |
| EP1383508B1 (en) * | 2001-04-05 | 2006-06-21 | Collagenex Pharmaceuticals, Inc. | Doxycycline for the treatment of acne |
| US7704959B2 (en) * | 2006-10-03 | 2010-04-27 | Dow Pharmaceutical Sciences | Azithromycin for the treatment of nodular acne |
| CA2892739A1 (en) * | 2006-12-21 | 2008-07-03 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of inflammatory skin disorders |
| WO2008079339A2 (en) | 2006-12-21 | 2008-07-03 | Paratek Pharmaceuticals, Inc. | Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections |
| CA2724412A1 (en) * | 2008-05-21 | 2009-11-26 | Galderma Research & Development | Maintenance therapy regimen for treating acne |
| CN102056481A (zh) * | 2008-06-05 | 2011-05-11 | 陶氏制药科学公司 | 包含低浓度的在水和水混溶性有机溶剂中的悬浮液形式的过氧苯甲酰的局部药物制剂 |
| JP2013500984A (ja) * | 2009-07-30 | 2013-01-10 | アラーガン、インコーポレイテッド | ダプソンとアダパレンの組み合わせ |
| US20140121188A1 (en) * | 2009-10-02 | 2014-05-01 | Foamix Ltd. | Compositions for the improved treatment of acne and related disorders |
| US9255068B2 (en) * | 2011-05-12 | 2016-02-09 | Warner Chilcott Company, Llc | Crystalline salts of (4S,4AS,5AR,12AS)-4-dimethylamino-3,10,12,12A-tetrahydroxy-7-[methoxy(methyl)amino)-methyl] acid amide and methods of using the same |
| IL225246A0 (en) * | 2012-03-15 | 2013-06-27 | Meir Eini | Methods for speeding up the restoration of skin normality and for treatment of impetigo |
| GB201615693D0 (en) * | 2016-09-15 | 2016-11-02 | Combinatorx Infection Ltd | Combinations |
-
2018
- 2018-07-20 CN CN201880048978.1A patent/CN111343991A/zh active Pending
- 2018-07-20 EP EP18779747.7A patent/EP3654988B1/en active Active
- 2018-07-20 BR BR112020000968-7A patent/BR112020000968A2/pt not_active Application Discontinuation
- 2018-07-20 KR KR1020207003934A patent/KR102662461B1/ko active Active
- 2018-07-20 CA CA3070663A patent/CA3070663A1/en active Pending
- 2018-07-20 MX MX2020000816A patent/MX2020000816A/es unknown
- 2018-07-20 JP JP2020524697A patent/JP2020527607A/ja active Pending
- 2018-07-20 US US16/632,121 patent/US20200222432A1/en not_active Abandoned
- 2018-07-20 AU AU2018303807A patent/AU2018303807B2/en active Active
- 2018-07-20 WO PCT/IB2018/000938 patent/WO2019016609A1/en not_active Ceased
- 2018-07-20 MA MA049641A patent/MA49641A/fr unknown
- 2018-07-20 ES ES18779747T patent/ES2962380T3/es active Active
-
2020
- 2020-01-19 IL IL272124A patent/IL272124A/en unknown
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