KR102641846B1 - 메틸-CpG 결합 단백질 2를 암호화하는 재조합 아데노-관련 바이러스의 경막 내 전달 - Google Patents

메틸-CpG 결합 단백질 2를 암호화하는 재조합 아데노-관련 바이러스의 경막 내 전달 Download PDF

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KR102641846B1
KR102641846B1 KR1020197017104A KR20197017104A KR102641846B1 KR 102641846 B1 KR102641846 B1 KR 102641846B1 KR 1020197017104 A KR1020197017104 A KR 1020197017104A KR 20197017104 A KR20197017104 A KR 20197017104A KR 102641846 B1 KR102641846 B1 KR 102641846B1
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mecp2
raav
vector
raav vector
virus
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KR20190126047A (ko
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케빈 포우스트
브라이언 케이. 카스파
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네이션와이드 칠드런스 하스피탈 인코포레이티드
오하이오 스테이트 이노베이션 파운데이션
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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KR1020197017104A 2016-11-17 2017-11-17 메틸-CpG 결합 단백질 2를 암호화하는 재조합 아데노-관련 바이러스의 경막 내 전달 Active KR102641846B1 (ko)

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Application Number Priority Date Filing Date Title
US201662423618P 2016-11-17 2016-11-17
US62/423,618 2016-11-17
PCT/US2017/062371 WO2018094251A1 (en) 2016-11-17 2017-11-17 Intrathecal delivery of recombinant adeno-associated virus encoding methyl-cpg binding protein 2

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KR20190126047A KR20190126047A (ko) 2019-11-08
KR102641846B1 true KR102641846B1 (ko) 2024-02-27

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US (3) US11583564B2 (https=)
EP (1) EP3541429A4 (https=)
JP (3) JP7106534B2 (https=)
KR (1) KR102641846B1 (https=)
CN (2) CN118490845A (https=)
AU (3) AU2017362491B2 (https=)
BR (1) BR112019009834B1 (https=)
CA (1) CA3044291A1 (https=)
CL (1) CL2019001354A1 (https=)
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MA (1) MA46863A (https=)
MX (1) MX2019005874A (https=)
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CN112601557B (zh) 2018-06-08 2025-06-06 诺华股份有限公司 用于测量药物产品效力的基于细胞的测定
KR20210124300A (ko) * 2019-02-04 2021-10-14 더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 Cln3 폴리뉴클레오티드의 아데노-관련 바이러스 전달
AU2020366242A1 (en) * 2019-10-18 2022-05-26 Research Institute At Nationwide Children's Hospital Materials and methods for the treatment of disorders associated mutations in the IRF2BPL gene
JP7684296B2 (ja) * 2019-11-22 2025-05-27 リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル Ｉｇｈｍｂｐ２遺伝子に関連する障害の治療のための材料および方法
EP4323010A1 (en) * 2021-04-13 2024-02-21 Research Institute at Nationwide Children's Hospital Recombinant adeno-associated virus encoding methyl-cpg binding protein 2 for treating pitt hopkins syndrome via intrathecal delivery
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JP2020503265A (ja) 2020-01-30
US20250312400A1 (en) 2025-10-09
CN110325219A (zh) 2019-10-11
EP3541429A4 (en) 2020-08-12
WO2018094251A1 (en) 2018-05-24
AU2023202598B2 (en) 2026-02-05
CL2019001354A1 (es) 2019-09-13
US11583564B2 (en) 2023-02-21
SA519401806B1 (ar) 2023-03-08
SG10202105090WA (en) 2021-06-29
EP3541429A1 (en) 2019-09-25
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US12357663B2 (en) 2025-07-15
IL266678A (en) 2019-07-31
RU2019118300A (ru) 2020-12-17
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BR112019009834A2 (pt) 2019-10-08
MX2019005874A (es) 2020-02-07
JP2024045289A (ja) 2024-04-02
CN118490845A (zh) 2024-08-16
MA46863A (fr) 2019-09-25
CN110325219B (zh) 2024-03-26
CA3044291A1 (en) 2018-05-24
AU2026200191A1 (en) 2026-01-29
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US20200179467A1 (en) 2020-06-11
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