KR102620652B1 - 미생물 콜로니화의 조절을 위한 치환된 톨란 - Google Patents

미생물 콜로니화의 조절을 위한 치환된 톨란 Download PDF

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KR102620652B1
KR102620652B1 KR1020207005214A KR20207005214A KR102620652B1 KR 102620652 B1 KR102620652 B1 KR 102620652B1 KR 1020207005214 A KR1020207005214 A KR 1020207005214A KR 20207005214 A KR20207005214 A KR 20207005214A KR 102620652 B1 KR102620652 B1 KR 102620652B1
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antibacterial
delete delete
tolan
hydroxy
substituted
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KR20200087122A (ko
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카렌 엠. 맥과이어
춘-체 차이
에밀리 엘. 플로시닉
알리샤 엠. 맥코믹
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바이오멘딕스, 엘엘씨
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020207005214A 2017-07-27 2018-07-26 미생물 콜로니화의 조절을 위한 치환된 톨란 Active KR102620652B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762537661P 2017-07-27 2017-07-27
US62/537,661 2017-07-27
US201862676676P 2018-05-25 2018-05-25
US62/676,676 2018-05-25
PCT/US2018/043833 WO2019023425A1 (en) 2017-07-27 2018-07-26 SUBSTITUTED TOLANES FOR THE MODULATION OF MICROBIAL COLONIZATION

Publications (2)

Publication Number Publication Date
KR20200087122A KR20200087122A (ko) 2020-07-20
KR102620652B1 true KR102620652B1 (ko) 2024-01-03

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KR1020207005214A Active KR102620652B1 (ko) 2017-07-27 2018-07-26 미생물 콜로니화의 조절을 위한 치환된 톨란

Country Status (13)

Country Link
US (2) US11351126B2 (enExample)
EP (1) EP3658128A4 (enExample)
JP (1) JP7266597B2 (enExample)
KR (1) KR102620652B1 (enExample)
CN (1) CN111526873B (enExample)
AU (1) AU2018306420B2 (enExample)
BR (1) BR112020001619A2 (enExample)
CA (1) CA3070427A1 (enExample)
IL (1) IL272188B (enExample)
MX (1) MX2020001043A (enExample)
MY (1) MY204404A (enExample)
SG (1) SG11202000708SA (enExample)
WO (1) WO2019023425A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018306420B2 (en) * 2017-07-27 2024-02-15 BioMendics, LLC Substituted tolans for the modulation of microbial colonization
KR102407606B1 (ko) * 2020-04-27 2022-06-10 경희대학교 산학협력단 송악 추출물을 포함하는 바이오필름 형성 억제용 조성물

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004505998A (ja) * 2000-08-15 2004-02-26 ノースイースタン、オハイオ、ユニバーシティーズ、カレッジ、オブ、メディシン ヘルペスウイルスまたはＮｅｉｓｓｅｒｉａｇｏｎｏｒｒｈｏｅａｅに感染した患者を処置する方法
US20110092578A1 (en) * 2004-10-18 2011-04-21 Monte Aaron P Broad Spectrum Gram-Positive Antimicrobials and Anthelmintics with Efficacy Against Drug-Resistant Strains and Mycobacterium Species
US20140178447A1 (en) 2011-08-31 2014-06-26 The Trustees Of Columbia University In The City Of New York Reduction of biofilms on medical devices
US20160296477A1 (en) 2015-04-08 2016-10-13 BioMendics, LLC Formulation and Process for Modulating Wound Healing

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3840527A (en) 1971-08-16 1974-10-08 Riker Laboratories Inc Haloalkylsulfonamido-substituted tolan and stilbene compounds
US5420361A (en) * 1992-02-05 1995-05-30 Bio-Technical Resources Formulation of and dehydration of hydroxylated diphenyl acetylenes
SG159388A1 (en) * 2003-01-08 2010-03-30 Chiron Corp Antibacterial agents
CA2934114A1 (en) * 2007-06-12 2008-12-18 Achaogen, Inc. Antibacterial agents
US8716355B2 (en) * 2007-06-20 2014-05-06 Kent State University Hydroxylated tolans and related compounds in the treatment of a cancer
WO2009126700A1 (en) * 2008-04-08 2009-10-15 Kent State University Hydroxylated tolans and related compounds as cosmetics or therapeutics for skin conditions
IT1399222B1 (it) 2010-01-28 2013-04-11 Pittiruti Catetere per la somministrazione parenterale di fluidi biomedicali
CN101914080B (zh) * 2010-08-05 2012-10-03 上海交通大学 苯并呋喃-3-甲酮取代苯基类化合物及其制备和应用
AU2018306420B2 (en) * 2017-07-27 2024-02-15 BioMendics, LLC Substituted tolans for the modulation of microbial colonization

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004505998A (ja) * 2000-08-15 2004-02-26 ノースイースタン、オハイオ、ユニバーシティーズ、カレッジ、オブ、メディシン ヘルペスウイルスまたはＮｅｉｓｓｅｒｉａｇｏｎｏｒｒｈｏｅａｅに感染した患者を処置する方法
US20110092578A1 (en) * 2004-10-18 2011-04-21 Monte Aaron P Broad Spectrum Gram-Positive Antimicrobials and Anthelmintics with Efficacy Against Drug-Resistant Strains and Mycobacterium Species
US20140178447A1 (en) 2011-08-31 2014-06-26 The Trustees Of Columbia University In The City Of New York Reduction of biofilms on medical devices
US20160296477A1 (en) 2015-04-08 2016-10-13 BioMendics, LLC Formulation and Process for Modulating Wound Healing

Also Published As

Publication number Publication date
AU2018306420A1 (en) 2020-02-06
SG11202000708SA (en) 2020-02-27
AU2018306420B2 (en) 2024-02-15
CA3070427A1 (en) 2019-01-31
EP3658128A4 (en) 2021-04-21
WO2019023425A1 (en) 2019-01-31
KR20200087122A (ko) 2020-07-20
EP3658128A1 (en) 2020-06-03
CN111526873A (zh) 2020-08-11
US20220296538A1 (en) 2022-09-22
IL272188B (en) 2022-08-01
JP7266597B2 (ja) 2023-04-28
MX2020001043A (es) 2020-08-17
IL272188A (en) 2020-03-31
US11351126B2 (en) 2022-06-07
CN111526873B (zh) 2025-03-04
US20200206154A1 (en) 2020-07-02
BR112020001619A2 (pt) 2020-07-21
JP2020529471A (ja) 2020-10-08
MY204404A (en) 2024-08-27

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