KR102589081B1 - 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스 - Google Patents

분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스 Download PDF

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Publication number
KR102589081B1
KR102589081B1 KR1020227022586A KR20227022586A KR102589081B1 KR 102589081 B1 KR102589081 B1 KR 102589081B1 KR 1020227022586 A KR1020227022586 A KR 1020227022586A KR 20227022586 A KR20227022586 A KR 20227022586A KR 102589081 B1 KR102589081 B1 KR 102589081B1
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South Korea
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ingestible device
housing
reservoir
dispensable
pressure
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KR20220101202A (ko
Inventor
미첼 로런스 존스
크리스토퍼 로렌 월
진 앨런 웨이
아론 올라푸르 로런스 필립슨
마크 사샤 드리릭
라이언 엘리엇 존스
네이선 존 멀러
앤드루 카를로스 갈런드
아이만 니크니아
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비오라 쎄라퓨틱스, 인크.
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Priority to KR1020237009208A priority Critical patent/KR20230042759A/ko
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Assigned to 비티 비드코, 인크. reassignment 비티 비드코, 인크. 권리의 전부이전등록 Assignors: 비오라 쎄라퓨틱스, 인크.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/07Endoradiosondes
    • A61B5/073Intestinal transmitters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00147Holding or positioning arrangements
    • A61B1/00148Holding or positioning arrangements using anchoring means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041Capsule endoscopes for imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3417Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3498Valves therefor, e.g. flapper valves, slide valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A61B5/0086Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/06Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
    • A61B5/065Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6861Capsules, e.g. for swallowing or implanting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/007Marking tablets or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3405Needle locating or guiding means using mechanical guide means
    • A61B2017/3409Needle locating or guiding means using mechanical guide means including needle or instrument drives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3417Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B2017/3454Details of tips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/10General characteristics of the apparatus with powered movement mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8218Gas operated
    • A61M2205/8225Gas operated using incorporated gas cartridges for the driving gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8275Mechanical
    • A61M2205/8281Mechanical spring operated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1042Alimentary tract
    • A61M2210/106Small intestine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30Hydrogen technology
    • Y02E60/36Hydrogen production from non-carbon containing sources, e.g. by water electrolysis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Human Computer Interaction (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Vending Machines For Individual Products (AREA)
KR1020227022586A 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스 Active KR102589081B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237009208A KR20230042759A (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US201662385553P 2016-09-09 2016-09-09
US62/385,553 2016-09-09
US201762478955P 2017-03-30 2017-03-30
US201762478753P 2017-03-30 2017-03-30
US62/478,955 2017-03-30
US62/478,753 2017-03-30
US201762480187P 2017-03-31 2017-03-31
US62/480,187 2017-03-31
US201762540873P 2017-08-03 2017-08-03
US62/540,873 2017-08-03
US201762545129P 2017-08-14 2017-08-14
US62/545,129 2017-08-14
KR1020197009660A KR102417504B1 (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
PCT/US2017/050642 WO2018049133A1 (en) 2016-09-09 2017-09-08 Electromechanical ingestible device for delivery of a dispensable substance

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020197009660A Division KR102417504B1 (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020237009208A Division KR20230042759A (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스

Publications (2)

Publication Number Publication Date
KR20220101202A KR20220101202A (ko) 2022-07-19
KR102589081B1 true KR102589081B1 (ko) 2023-10-17

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Application Number Title Priority Date Filing Date
KR1020227022586A Active KR102589081B1 (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
KR1020237009208A Ceased KR20230042759A (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
KR1020197009660A Active KR102417504B1 (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
KR1020247024062A Active KR102737336B1 (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스

Family Applications After (3)

Application Number Title Priority Date Filing Date
KR1020237009208A Ceased KR20230042759A (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
KR1020197009660A Active KR102417504B1 (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
KR1020247024062A Active KR102737336B1 (ko) 2016-09-09 2017-09-08 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스

Country Status (9)

Country Link
US (3) US20180070857A1 (enExample)
EP (3) EP4467182A3 (enExample)
JP (4) JP2019526423A (enExample)
KR (4) KR102589081B1 (enExample)
CN (2) CN115591091A (enExample)
AU (2) AU2017322324B2 (enExample)
CA (2) CA3036364A1 (enExample)
IL (3) IL305187A (enExample)
WO (1) WO2018049133A1 (enExample)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3799776B1 (en) 2014-09-25 2025-11-26 BT Bidco, Inc. Electromechanical pill device with localization capabilities
AU2016258179B2 (en) 2015-05-06 2021-07-01 Synagile Corporation Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use
EP4467182A3 (en) 2016-09-09 2025-01-15 Biora Therapeutics, Inc. Electromechanical ingestible device for delivery of a dispensable substance
EP3551034A1 (en) 2016-12-07 2019-10-16 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
WO2018112255A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an immunosuppressant
CA3046019A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a tlr modulator
CA3045310A1 (en) 2016-12-14 2018-06-21 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
CN110072551B (zh) 2016-12-14 2023-05-23 比奥拉治疗股份有限公司 使用利用可摄入装置释放的il-12/il-23抑制剂治疗胃肠道疾病
US11134889B2 (en) 2016-12-14 2021-10-05 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a SMAD7 inhibitor
CN110072519A (zh) 2016-12-14 2019-07-30 普罗根尼蒂公司 使用jak抑制剂治疗胃肠道疾病及装置
EP3600416B1 (en) * 2017-03-30 2023-06-07 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
CA3054156A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist
IL268900B2 (en) 2017-03-31 2023-11-01 Biora Therapeutics Inc Localization systems and methods for an ingestible device
CA3063711A1 (en) 2017-05-17 2018-11-22 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
US11541015B2 (en) 2017-05-17 2023-01-03 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
US10722220B2 (en) * 2017-12-06 2020-07-28 James Phillip Jones Sampling system capsule
US20210228157A1 (en) * 2017-12-06 2021-07-29 James Phillip Jones Sampling capsule system and methods
US12582809B2 (en) 2018-01-26 2026-03-24 Bt Bidco, Inc. Treatment of a disease of the gastrointestinal tract with a PDE4 inhibitor
WO2019178084A1 (en) * 2018-03-12 2019-09-19 Sameer Sonkusale Acquisition of samples for evaluating bacterial demographics
US12083303B2 (en) 2019-01-21 2024-09-10 Vibrant Ltd. Device and method for delivering a flowable ingestible medicament into the gastrointestinal tract of a user
EP3793667A1 (en) 2018-05-17 2021-03-24 Massachusetts Institute of Technology Systems for electrical stimulation
EP3801212A1 (en) * 2018-06-06 2021-04-14 Progenity, Inc. Ingestible device with on-board fluorometer and related systems and methods
CN108784634B (zh) * 2018-06-15 2023-08-04 安翰科技(武汉)股份有限公司 可自动密封的采样胶囊内窥镜
US12227565B2 (en) 2018-06-20 2025-02-18 Biora Therapeutics, Inc. Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine
US20200038000A1 (en) * 2018-08-06 2020-02-06 Nimble Science Ltd. Ingestible apparatus and method for collecting samples in the gastrointestinal tract and/or delivering health-related fluid thereto
US20210307733A1 (en) * 2018-08-06 2021-10-07 Nimble Science Ltd. Ingestible apparatus and method for collecting samples in the gastrointestinal tract and/or delivering health-related substance thereto
WO2020106757A1 (en) * 2018-11-19 2020-05-28 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
CA3125091A1 (en) 2019-01-03 2020-07-09 Vibrant Ltd. Device and method for delivering an ingestible medicament into the gastrointestinal tract of a user
GB201900780D0 (en) * 2019-01-21 2019-03-06 Vibrant Ltd Device and method for delivering a flowable ingestible medicament into the gastrointestinal tract of a user
CN113329777B (zh) * 2019-02-01 2024-01-09 诺和诺德股份有限公司 具有致动机构的医疗装置
WO2020160399A1 (en) 2019-02-01 2020-08-06 Massachusetts Institute Of Technology Systems and methods for liquid injection
CN113660899B (zh) * 2019-04-01 2024-05-14 吉温成象有限公司 体内免疫测定系统
EP3980110A1 (en) * 2019-06-07 2022-04-13 Novo Nordisk A/S Ingestible device with delivery member detachment
CA3149604A1 (en) 2019-08-29 2021-03-04 Desmond Ian John Morrow Intraruminal device
KR102412207B1 (ko) * 2019-10-11 2022-06-27 원광대학교산학협력단 확장형 구조를 갖는 위체류 약물전달장치 및 이의 제조 방법
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
MX2021009208A (es) * 2020-04-06 2022-01-24 Workhorse Group Inc Sistemas y metodos de vehiculos voladores.
KR102426727B1 (ko) * 2020-04-17 2022-07-28 성균관대학교산학협력단 방출 속도 조절 경구용 약물 전달 장치 및 방출 속도 조절 경구용 약물 전달 장치의 제조 방법
WO2021222274A1 (en) * 2020-04-27 2021-11-04 Cornell University An automated controlled release device for livestock management and methods of use thereof
CN116171179A (zh) 2020-08-08 2023-05-26 诺和诺德股份有限公司 管腔可插入胶囊
EP4192567A1 (en) * 2020-08-10 2023-06-14 Massachusetts Institute Of Technology Drug delivery device
EP4213761A4 (en) * 2020-09-15 2024-12-11 SynAgile Corporation DEVICES AND METHODS FOR CONTINUOUS EXTRUSION OF A DRUG INTO THE MOUTH
CN111973267B (zh) * 2020-09-27 2021-09-24 张海民 一种能够控制注射计量的微波消融针
IL301194A (en) 2020-09-30 2023-05-01 Novo Nordisk As Lumen insertable capsule
WO2022069606A1 (en) * 2020-09-30 2022-04-07 Novo Nordisk A/S A swallowable capsule device
US20240017045A1 (en) * 2020-10-21 2024-01-18 Massachusetts Institute Of Technology Gravity based drug delivery device
EP4266973A1 (en) * 2020-12-22 2023-11-01 Stryker Corporation Systems and methods for medical imaging illumination
EP4302816A4 (en) * 2021-03-05 2024-05-01 Bitherapeutics Inc. ORAL DRUG ADMINISTRATION
WO2022235737A1 (en) * 2021-05-07 2022-11-10 Dropworks, Inc. Narrowed conduits
KR20240089599A (ko) * 2021-10-28 2024-06-20 바이오그레일 에이피에스 고용량 약물 전달 장치
CN114099921B (zh) * 2021-11-04 2022-07-22 北京理工大学 一种体内弯曲区域爆炸冲击释药含能微系统
EP4432906A4 (en) * 2021-11-19 2025-09-17 Atmo Biosciences Ltd THERAPEUTIC PAYLOAD DELIVERY MECHANISM
CN119173296A (zh) * 2022-03-18 2024-12-20 比奥拉治疗股份有限公司 用于将治疗剂递送至胃肠道的可摄取装置
CN116832304A (zh) * 2022-03-23 2023-10-03 四川阿赛斯生物科技有限公司 施药器、施药方法、控制器、施药系统和存储介质
CN115165629B (zh) * 2022-06-28 2025-05-13 东北大学 一种岩石岩爆类型倾向性的评估方法
EP4378516B1 (en) * 2022-11-30 2026-01-21 Stichting IMEC Nederland Ingestible device for sampling material and delivering drug
WO2024184282A1 (en) 2023-03-03 2024-09-12 Novo Nordisk A/S Lumen insertable capsule
WO2025071738A2 (en) * 2023-07-21 2025-04-03 Massachusetts Institute Of Technology Oral pill gastric retention and disassembly designs
CN121752327A (zh) * 2023-09-01 2026-03-27 比奥拉治疗股份有限公司 可摄入药物递送装置
EP4563094A1 (en) * 2023-11-28 2025-06-04 Stichting IMEC Nederland Ingestible device and method for sampling material using a heat dependent actuating mechanism
WO2025208126A1 (en) * 2024-03-29 2025-10-02 Picocyl, Llc Gas canisters, caps for gas canisters, and methods for making them
ES3037764A1 (es) * 2024-04-05 2025-10-06 Endotronic S L Capsula biocompatible de activacion magnetica, sistema para liberacion de medicamentos activado magneticamente y metodo para la liberacion de medicamentos mediante activacion magnetica

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007312850A (ja) * 2006-05-23 2007-12-06 Olympus Medical Systems Corp カプセル型医療装置およびこれを用いた薬剤導入システム
JP2011093614A (ja) * 2009-09-29 2011-05-12 Toppan Printing Co Ltd 包装容器
WO2015059569A1 (en) * 2013-09-26 2015-04-30 Medimetrics Personalized Drug Delivery, B.V. Delivery capsule with threshold release

Family Cites Families (166)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH337989A (fr) 1957-04-09 1959-04-30 Perrenoud Jean Pierre Dr Capsule
US3057344A (en) 1957-05-21 1962-10-09 Abella Carlos Alberto Capsule for the study of the digestive tract and method of using the same
US3315660A (en) 1963-08-08 1967-04-25 Carlos A Abella Capsule for insertion in the digestive track
US3485235A (en) 1967-12-04 1969-12-23 Ronald Felson Capsule for the study and treatment of the digestive tract
US4036214A (en) 1975-04-14 1977-07-19 Louis Bucalo Fluid-collecting and microorganism-detecting devices
US4172446A (en) 1974-12-20 1979-10-30 Louis Bucalo Apparatus for collecting body fluids
US4239040A (en) 1976-10-19 1980-12-16 Kabushiki Kaisha Daini Seikosha Capsule for medical use
US4281645A (en) 1977-06-28 1981-08-04 Duke University, Inc. Method and apparatus for monitoring metabolism in body organs
US4481952A (en) 1978-03-22 1984-11-13 Jerzy Pawelec Device for the study of the alimentary canal
JPS5588732A (en) 1978-12-26 1980-07-04 Olympus Optical Co Endoscope
DE2928477C3 (de) 1979-07-14 1982-04-15 Battelle-Institut E.V., 6000 Frankfurt Vorrichtung zur Freisetzung von Substanzen an definierten Orten des Verdauungstraktes
JPS57163309A (en) 1981-04-01 1982-10-07 Olympus Optical Co Ltd Capsule apparatus for medical use
US4522625A (en) 1982-09-29 1985-06-11 Alza Corporation Drug dispenser comprising wall formed of semipermeable member and enteric member
AU2091583A (en) 1982-11-03 1984-05-10 Gec-Xpelair Ltd. Actuator responsive to heat
FR2565828A1 (fr) * 1983-11-10 1985-12-20 Alby Albert Ballonnet a valve detachable d'un catheter destine a sa mise en place
US4573447A (en) 1985-02-19 1986-03-04 Sunbelt America Corporation Chemical heater
US4844076A (en) 1988-08-26 1989-07-04 The Johns Hopkins University Ingestible size continuously transmitting temperature monitoring pill
US5167626A (en) 1990-10-02 1992-12-01 Glaxo Inc. Medical capsule device actuated by radio-frequency (RF) signal
US5170801A (en) 1990-10-02 1992-12-15 Glaxo Inc. Medical capsule device actuated by radio-frequency (rf) signal
US5217449A (en) 1990-12-11 1993-06-08 Miyarisan Kabushiki Kaisha Medical capsule and apparatus for activating the same
US5279607A (en) 1991-05-30 1994-01-18 The State University Of New York Telemetry capsule and process
US5395366A (en) 1991-05-30 1995-03-07 The State University Of New York Sampling capsule and process
US5318557A (en) 1992-07-13 1994-06-07 Elan Medical Technologies Limited Medication administering device
US5316015A (en) 1992-07-30 1994-05-31 Sinaiko Robert J Externally controlled intestinal content sampler
IL108352A (en) 1994-01-17 2000-02-29 Given Imaging Ltd In vivo video camera system
US5857998A (en) 1994-06-30 1999-01-12 Boston Scientific Corporation Stent and therapeutic delivery system
ZA9610374B (en) 1995-12-11 1997-06-23 Elan Med Tech Cartridge-based drug delivery device
US5738110A (en) 1996-05-29 1998-04-14 Beal; Charles B. Device for the diagnosis of certain gastrointestinal pathogens
US5971942A (en) 1996-12-03 1999-10-26 Gu; Howard H. Intestinal fluid sampler
US5951538A (en) 1997-08-07 1999-09-14 Ceramatec, Inc. Gas generating device for delivering beneficial agents to a body cavity
DE19801573A1 (de) 1998-01-19 1999-07-22 Suchatzki Bernd Ulrich Dr Sammler für lokale Probeflüssigkeiten und Verwendung eines solchen Sammlers im menschlichen oder tierischen Verdauugssystem
US6369039B1 (en) 1998-06-30 2002-04-09 Scimed Life Sytems, Inc. High efficiency local drug delivery
IL126727A (en) 1998-10-22 2006-12-31 Given Imaging Ltd A method of bringing a device to the goal
US6576429B1 (en) 1999-10-26 2003-06-10 Alimenta Diagnostics Ab Apparatus for intestinal sampling and use thereof
US6344027B1 (en) 1999-12-08 2002-02-05 Scimed Life Systems, Inc. Needle-less injection apparatus and method
GB9930001D0 (en) 1999-12-21 2000-02-09 Phaeton Research Ltd An ingestible device
GB9930000D0 (en) * 1999-12-21 2000-02-09 Phaeton Research Ltd An ingestible device
US20020099310A1 (en) 2001-01-22 2002-07-25 V-Target Ltd. Gastrointestinal-tract sensor
US8055329B2 (en) 2001-01-22 2011-11-08 Spectrum Dynamics Llc Ingestible device for radioimaging of the gastrointestinal tract
US7553276B2 (en) 2001-01-16 2009-06-30 Given Imaging Ltd. Method and device for imaging body lumens
CN100469308C (zh) 2001-03-14 2009-03-18 吉温成象有限公司 检测活体内色度异常的可吞咽胶囊和系统
EP1243524A3 (en) * 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmaceutical kit for oxygen-sensitive drugs
ATE324830T1 (de) 2001-05-17 2006-06-15 Faergklaemman Ab Probenentnahmevorrichtung und verfahren zur entnahme von proben von körpersubstanzen sowie verfahren zur herstellung einer probenentnahmevorrichtung
JP4782309B2 (ja) * 2001-05-25 2011-09-28 花王株式会社 容器
US7160258B2 (en) 2001-06-26 2007-01-09 Entrack, Inc. Capsule and method for treating or diagnosing the intestinal tract
GB0118266D0 (en) 2001-07-26 2001-09-19 Powderject Res Ltd Silencing device and method for needleless syringe
US7615234B2 (en) 2001-09-11 2009-11-10 Glide Pharmaceutical Technologies Limited Drug delivery technology
CA2373854A1 (en) 2002-02-28 2003-08-28 Alain Moreau Methods of diagnosing and counteracting adolescent idiopathic scoliosis
US7797033B2 (en) 2002-04-08 2010-09-14 Smart Pill Corporation Method of using, and determining location of, an ingestible capsule
US20040254455A1 (en) 2002-05-15 2004-12-16 Iddan Gavriel J. Magneic switch for use in a system that includes an in-vivo device, and method of use thereof
US7662093B2 (en) 2002-09-30 2010-02-16 Given Imaging, Ltd. Reduced size imaging device
AU2003285756A1 (en) 2002-12-16 2004-07-09 Given Imaging Ltd. Device, system and method for selective activation of in vivo sensors
EP1587407B1 (en) 2002-12-26 2012-03-07 Given Imaging Ltd. Immobilizable in vivo sensing device
CA2514392A1 (en) * 2003-01-29 2004-08-12 E-Pill Pharma Ltd. Active drug delivery in the gastrointestinal tract
JP4149838B2 (ja) 2003-03-04 2008-09-17 オリンパス株式会社 カプセル型医療装置
US20040199054A1 (en) 2003-04-03 2004-10-07 Wakefield Glenn Mark Magnetically propelled capsule endoscopy
US7611480B2 (en) 2003-04-24 2009-11-03 Levy Mark M Gastrointestinal bioreactor
EP1623010A4 (en) 2003-04-25 2007-12-26 Janssen Pharmaceutica Nv PRESERVATION OF RNA IN A BIOLOGICAL SAMPLE
EP1643906A2 (en) 2003-06-12 2006-04-12 University of Utah Research Foundation Apparatus, systems and methods for diagnosing carpal tunnel syndrome
US20050065441A1 (en) 2003-08-29 2005-03-24 Arkady Glukhovsky System, apparatus and method for measurement of motion parameters of an in-vivo device
JP4445732B2 (ja) 2003-08-29 2010-04-07 オリンパス株式会社 被検体内導入装置および無線型被検体内情報取得システム
JP2005074031A (ja) 2003-09-01 2005-03-24 Pentax Corp カプセル内視鏡
JP4520126B2 (ja) * 2003-09-29 2010-08-04 オリンパス株式会社 カプセル型医療装置システム
JP4733918B2 (ja) * 2003-10-01 2011-07-27 オリンパス株式会社 カプセル投薬システム
EP1530950A1 (en) 2003-11-12 2005-05-18 Färgklämman AB Sampling device and method of producing thereof
WO2005062716A2 (en) 2003-12-31 2005-07-14 Given Imaging Ltd. Apparatus, system and method to indicate in-vivo device location
US8206285B2 (en) 2003-12-31 2012-06-26 Given Imaging Ltd. Apparatus, system and method to indicate in-vivo device location
WO2005112895A2 (en) 2004-05-20 2005-12-01 Spectrum Dynamics Llc Ingestible device platform for the colon
ATE481032T1 (de) 2004-05-21 2010-10-15 Given Imaging Ltd Vorrichtung, system und verfahren zur in-vivo- probenentnahme
RU2269343C1 (ru) 2004-06-18 2006-02-10 Государственное учреждение научный центр здоровья детей РАМН (ГУ НЦЗД РАМН) Способ подготовки к проведению видеокапсульной эндоскопии
WO2006001020A2 (en) 2004-06-28 2006-01-05 Given Imaging Ltd. Device, system, and method for in-vivo analysis
CN101237903A (zh) * 2005-01-18 2008-08-06 皇家飞利浦电子股份有限公司 用于控制所摄入胶囊通过的系统和方法
CN101208039A (zh) 2005-01-18 2008-06-25 皇家飞利浦电子股份有限公司 用于对消化道中的流体采样的可摄入电控胶囊
JP2008532568A (ja) * 2005-01-18 2008-08-21 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 電子制御されるカプセル
US8852083B2 (en) 2005-02-04 2014-10-07 Uti Limited Partnership Self-stabilized encapsulated imaging system
US20070043320A1 (en) 2005-02-09 2007-02-22 Kenany Saad A Microstream injector
CA2616010C (en) 2005-07-20 2013-11-05 Neil R. Euliano Medication compliance system and associated methods
US20070027362A1 (en) 2005-07-27 2007-02-01 Olympus Medical Systems Corp. Infrared observation system
CN101282677B (zh) 2005-10-05 2010-07-28 奥林巴斯医疗株式会社 胶囊式医疗装置、其引导系统和引导方法、及被检体内插入装置
US20070092401A1 (en) 2005-10-26 2007-04-26 Feier Liao Devices and methods for sample collection and analysis
EP1954197A2 (en) 2005-11-22 2008-08-13 Stichting Top Institute Food and Nutrition Sampling device for in vivo sampling of liquids from the gastrointestinal tract, process for the production thereof and mould or mask for use in the production process
US20090131784A1 (en) 2005-12-29 2009-05-21 Ido Betesh System and method of in-vivo magnetic position determination
IL182332A (en) 2006-03-31 2013-04-30 Given Imaging Ltd A system and method for assessing a patient's condition
EP1867360B1 (fr) 2006-06-15 2009-02-11 Ela Medical Dispositif médical implantable actif, notamment dispositif de stimulation, resynchronisation, défibrillation et/ou cardioversion, comprenant des moyens d'alerte prédictive d'une aggravation de l'état clinique du patient
WO2007148238A1 (en) 2006-06-20 2007-12-27 Koninklijke Philips Electronics, N.V. Electronic capsule for treating gastrointestinal disease
CN101495164A (zh) * 2006-07-28 2009-07-29 贝克顿·迪金森公司 脉管进入装置容积位移
US20080027415A1 (en) 2006-07-28 2008-01-31 Becton, Dickinson And Company Vascular access device volume displacement
WO2008038199A1 (en) 2006-09-25 2008-04-03 Koninklijke Philips Electronics, N.V. Medicament delivery apparatus
WO2008053396A2 (en) 2006-10-31 2008-05-08 Koninklijke Philips Electronics N.V. Design of swallowable multi-nozzle, dosing device for releasing medicines in the gastrointesinal tract
CN100588378C (zh) * 2006-11-16 2010-02-10 重庆大学 消化道遥控释药胶囊系统
US9730573B2 (en) 2007-03-20 2017-08-15 Given Imaging Ltd. Narrow band in-vivo imaging device
JP4932588B2 (ja) 2007-05-08 2012-05-16 オリンパス株式会社 画像処理装置および画像処理プログラム
WO2009054806A1 (en) 2007-10-22 2009-04-30 Agency For Science, Technology And Research Fused gene(s)
ES2620816T3 (es) 2007-11-12 2017-06-29 Novineon Healthcare Technology Partners Gmbh Dispositivo para la detección de hemorragias
CN101945613B (zh) 2008-02-18 2014-08-13 皇家飞利浦电子股份有限公司 为患者用药
US8845535B2 (en) 2008-02-22 2014-09-30 Herbert Michael Pinedo Device for detecting a medical condition or disease
US20100111763A1 (en) 2008-03-18 2010-05-06 Kahn Laurence H Examination Device for Blood Detection
JP5670326B2 (ja) 2008-06-25 2015-02-18 メディメトリクス ペルソナリズド ドルグ デリヴェリー ベー ヴェ 複数の薬剤リザーバを有する電子ピル
CN107049928A (zh) 2008-07-07 2017-08-18 皇家飞利浦电子股份有限公司 包括储药器的电子药丸
US8423122B2 (en) 2008-07-10 2013-04-16 Given Imaging Ltd. Localization of capsule with a synthetic source of quadrupoles and dipoles
US8162969B2 (en) * 2008-10-16 2012-04-24 Obalon Therapeutics, Inc. Intragastric device
WO2010086859A1 (en) 2009-01-29 2010-08-05 Given Imaging Ltd. Device,system and method for detection of bleeding
DE102009009165B4 (de) 2009-02-16 2018-12-27 Siemens Healthcare Gmbh Verfahren und Vorrichtung zur Bestimmung eines von einer Endoskopiekapsel in einem Patienten zurückgelegten Weges
WO2010096929A1 (en) 2009-02-25 2010-09-02 Diagnocure Inc. Method for detecting metastasis of gi cancer
CA2761033A1 (en) 2009-03-31 2010-10-14 The Smartpill Corporation Method of determining body exit of an ingested capsule
EP2424464A4 (en) 2009-04-30 2015-04-15 Svip 2 Llc DEVICE AND METHOD FOR THE TREATMENT OF STOMACH-DARM AND METABOLISM DISEASES
KR100931946B1 (ko) 2009-06-10 2009-12-15 주식회사 인트로메딕 캡슐 내시경에 의해 촬영된 이미지 데이터를 저장하고 있는 서버로부터 관심있는 데이터를 우선하여 단말기에 수신하여 확인할 수 있도록 하는 서버-클라이언트 시스템의 이미지 데이터 전송 프로세싱 방법
US20120184827A1 (en) 2009-06-16 2012-07-19 Shoulamit Cohen Shwartz Miniature disease optical spectroscopy diagnostic system
US20120136209A1 (en) 2009-08-05 2012-05-31 Tel Hashomer Medical Research Infrastructure And Services, Ltd. Methods and devices for providing information useful in the diagnosis of abnormalities of the gastrointestinal tract
JP5497176B2 (ja) 2009-08-12 2014-05-21 コーニンクレッカ フィリップス エヌ ヴェ 圧縮可能な薬品貯槽を備える薬品送出装置
US20130018279A1 (en) 2009-09-01 2013-01-17 Pathway Genomics "blood sample collection apparatus and kits"
US9014799B2 (en) * 2009-10-08 2015-04-21 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including electrically-actuated permeation enhancement
EP2494351B1 (en) 2009-10-26 2016-06-08 Externautics S.p.A. Colon and rectal tumor markers and methods of use thereof
US9026192B2 (en) 2009-11-24 2015-05-05 Given Imaging Ltd Device and method for in vivo imaging
UA109424C2 (uk) * 2009-12-02 2015-08-25 Фармацевтичний продукт, фармацевтична таблетка з електронним маркером і спосіб виготовлення фармацевтичної таблетки
CN105999526B (zh) 2009-12-24 2019-07-05 拉尼医疗有限公司 可吞咽式药剂递送装置和药剂递送方法
WO2011114332A1 (en) 2010-03-17 2011-09-22 Photopill Medical Ltd. Capsule phototherapy
US20120253204A1 (en) * 2010-03-17 2012-10-04 Photopill Medical Ltd. Systems and methods for phototherapeutic treatment of rectal diseases
CN103209632B (zh) 2010-11-16 2017-03-15 基文影像公司 用于执行光谱分析的体内成像装置和方法
US9415004B2 (en) * 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8969293B2 (en) 2010-12-23 2015-03-03 Rani Therapeutics, Llc Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8809271B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising liraglutide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
EP2623017B1 (en) 2011-04-01 2017-11-08 Olympus Corporation Receiving device and capsule endoscope system
US8586384B2 (en) 2011-04-05 2013-11-19 Olympus Corporation Method of collecting duodenal specimen to detect upper digestive system disease without using pancreatic or bile stimulant
JP6029664B2 (ja) 2011-06-29 2016-11-24 ラニ セラピューティクス, エルエルシー 嚥下可能な薬物送達デバイスを用いる腸管の内腔へ送達するための治療剤製剤
CN103827668B (zh) 2011-08-04 2016-04-20 基文影像公司 用于体内免疫测定的装置、系统和方法
CA2848162C (en) 2011-09-12 2023-03-14 Creatics Llc Non-invasive methods of detecting target molecules
US8801630B2 (en) 2011-09-30 2014-08-12 Olympus Medical Systems Corp. Method of taking out liquid present inside subject therefrom
JP2015509744A (ja) 2011-12-15 2015-04-02 ギブン イメージング リミテッドGiven Imaging Ltd. 消化管内における出血のインビボ検出のための装置、システムおよび方法
US9795330B2 (en) 2011-12-15 2017-10-24 Given Imaging Ltd. Device, system and method for in-vivo detection of bleeding in the gastrointestinal tract
EP3725234A1 (en) 2012-02-17 2020-10-21 Progenity, Inc. Ingestible medical device
WO2013145855A1 (ja) * 2012-03-27 2013-10-03 ソニー株式会社 カプセル型医療装置および医療システム
US20150065926A1 (en) 2012-04-12 2015-03-05 Sony Corporation Capsule-type medical device and system
WO2014028902A1 (en) 2012-08-16 2014-02-20 Rock West Solutions, Inc. System and methods for locating a radiofrequency transceiver in the human body
DE102012025143A1 (de) * 2012-11-07 2014-05-08 Heraeus Medical Gmbh Verfahren zur Wirkstofffreisetzung und Wirkstofffreisetzungssysteme
US8926526B2 (en) 2012-11-30 2015-01-06 L. Zane Shuck Patient in vivo gut diagnostic and treatment tool
EP2967509A4 (en) 2013-03-14 2016-11-16 Spot On Sciences Inc COLLECTION AND CONSERVATION OF BIOLOGICAL SAMPLES
PL2968071T3 (pl) * 2013-03-15 2021-12-20 Rani Therapeutics, Llc Urządzenie do doustnego dostarczania związków leczniczych
GB201304738D0 (en) 2013-03-15 2013-05-01 Mars Inc Sampling Device
WO2014210226A1 (en) 2013-06-25 2014-12-31 Public Service Solutions, Inc. Side-scan infrared imaging devices
US9324145B1 (en) 2013-08-08 2016-04-26 Given Imaging Ltd. System and method for detection of transitions in an image stream of the gastrointestinal tract
WO2015099749A1 (en) 2013-12-27 2015-07-02 Capso Vision Inc. Capsule camera device with multi-spectral light sources
WO2015147305A1 (ja) * 2014-03-28 2015-10-01 テルモ株式会社 包装された薬剤充填容器体
RU2766335C2 (ru) 2014-06-11 2022-03-15 Массачусетс Инститьют Оф Текнолоджи Удерживаемые структуры и связанные способы
US20160066855A1 (en) 2014-09-05 2016-03-10 Elwha LLC, a limited liability company of the State of Delaware Systems, methods, and devices addressing the gastro-intestinal tract
EP3799776B1 (en) 2014-09-25 2025-11-26 BT Bidco, Inc. Electromechanical pill device with localization capabilities
WO2016054015A1 (en) 2014-09-30 2016-04-07 The Regents Of The University Of California Active agent delivery devices and methods of using the same
US10300259B2 (en) 2014-10-22 2019-05-28 Purdue Research Foundation Smart capsule with GI-tract-location-specific payload release
CN105877685B (zh) 2015-01-26 2019-03-15 香港中文大学 内窥镜胶囊和内窥镜系统
CN107683107B (zh) 2015-06-02 2021-06-04 基文影像公司 用于体内免疫测定的装置、系统和方法
EP3108810A1 (en) 2015-06-23 2016-12-28 Valtronic Technologies (Holding) SA Ingestible device for measuring glucose concentration
US20180193621A1 (en) 2015-06-30 2018-07-12 Entrega Inc. Device for oral delivery of active agents
JP2017012395A (ja) 2015-06-30 2017-01-19 富士フイルム株式会社 内視鏡システム及び内視鏡システムの作動方法
US10610351B2 (en) 2016-03-08 2020-04-07 Picocyl Gas canisters and methods for making them
CA3034263A1 (en) 2016-08-18 2018-02-22 Mitchell Lawrence Jones Sampling systems and related materials and methods
EP4467182A3 (en) 2016-09-09 2025-01-15 Biora Therapeutics, Inc. Electromechanical ingestible device for delivery of a dispensable substance
EP3512433B1 (en) 2016-09-15 2023-06-07 Biora Therapeutics, Inc. Fluid sampling device
AU2017100274A4 (en) 2017-03-08 2017-04-27 Helimods Pty Ltd The Powered Aero Loader lifts, at a press of a button, Stryker Power Pro XT and Stryker Performance Pro (with adaption) stretchers and allows these stretchers to be secured into the aircraft. The Powered Aero Loaders aircraft interface specifically distributes loads generated by the stretcher systems during loading, unloading and inflight to allow for safe carriage in aircraft.
CA3054159A1 (en) 2017-03-30 2018-10-04 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor
IL268900B2 (en) 2017-03-31 2023-11-01 Biora Therapeutics Inc Localization systems and methods for an ingestible device
CA3063711A1 (en) 2017-05-17 2018-11-22 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
CN108784634B (zh) 2018-06-15 2023-08-04 安翰科技(武汉)股份有限公司 可自动密封的采样胶囊内窥镜
WO2020041774A1 (en) 2018-08-23 2020-02-27 Baywind Bioventures Capsule device for delivery of active agent to gastrointestinal tract
WO2020106757A1 (en) 2018-11-19 2020-05-28 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
CN113329777B (zh) 2019-02-01 2024-01-09 诺和诺德股份有限公司 具有致动机构的医疗装置
WO2020160399A1 (en) 2019-02-01 2020-08-06 Massachusetts Institute Of Technology Systems and methods for liquid injection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007312850A (ja) * 2006-05-23 2007-12-06 Olympus Medical Systems Corp カプセル型医療装置およびこれを用いた薬剤導入システム
JP2011093614A (ja) * 2009-09-29 2011-05-12 Toppan Printing Co Ltd 包装容器
WO2015059569A1 (en) * 2013-09-26 2015-04-30 Medimetrics Personalized Drug Delivery, B.V. Delivery capsule with threshold release

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