KR102562514B1 - 광안정성 및 용출성이 우수한 의약 제제 - Google Patents

광안정성 및 용출성이 우수한 의약 제제 Download PDF

Info

Publication number
KR102562514B1
KR102562514B1 KR1020207016914A KR20207016914A KR102562514B1 KR 102562514 B1 KR102562514 B1 KR 102562514B1 KR 1020207016914 A KR1020207016914 A KR 1020207016914A KR 20207016914 A KR20207016914 A KR 20207016914A KR 102562514 B1 KR102562514 B1 KR 102562514B1
Authority
KR
South Korea
Prior art keywords
solid preparation
polymer
formula
coating layer
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020207016914A
Other languages
English (en)
Korean (ko)
Other versions
KR20200089290A (ko
Inventor
나오미 하야시
마사토 고미
쇼헤이 아이카와
Original Assignee
시오노기세야쿠 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=66540251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102562514(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 시오노기세야쿠 가부시키가이샤 filed Critical 시오노기세야쿠 가부시키가이샤
Publication of KR20200089290A publication Critical patent/KR20200089290A/ko
Application granted granted Critical
Publication of KR102562514B1 publication Critical patent/KR102562514B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/802—Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics
    • A61K6/813—Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics comprising iron oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/884—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Ceramic Engineering (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Testing Resistance To Weather, Investigating Materials By Mechanical Methods (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
KR1020207016914A 2017-11-17 2018-11-15 광안정성 및 용출성이 우수한 의약 제제 Active KR102562514B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2017222068 2017-11-17
JPJP-P-2017-222068 2017-11-17
PCT/JP2018/042220 WO2019098259A1 (ja) 2017-11-17 2018-11-15 光安定性および溶出性に優れた医薬製剤

Publications (2)

Publication Number Publication Date
KR20200089290A KR20200089290A (ko) 2020-07-24
KR102562514B1 true KR102562514B1 (ko) 2023-08-03

Family

ID=66540251

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207016914A Active KR102562514B1 (ko) 2017-11-17 2018-11-15 광안정성 및 용출성이 우수한 의약 제제

Country Status (15)

Country Link
US (2) US12064438B2 (https=)
EP (2) EP4650773A3 (https=)
JP (2) JP6660644B2 (https=)
KR (1) KR102562514B1 (https=)
CN (1) CN111615390A (https=)
AR (1) AR113890A1 (https=)
AU (1) AU2018369241B2 (https=)
BR (1) BR112020009634B1 (https=)
CA (2) CA3299815A1 (https=)
ES (1) ES3058136T3 (https=)
IL (1) IL274625B (https=)
MX (1) MX2020004680A (https=)
PL (1) PL3711767T3 (https=)
TW (1) TWI795462B (https=)
WO (1) WO2019098259A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX395463B (es) * 2018-04-24 2025-03-25 Shionogi & Co Forma de dosificacion solida que tiene excelente estabilidad
KR102501180B1 (ko) * 2018-04-24 2023-02-21 시오노기세야쿠 가부시키가이샤 안정성이 우수한 고형 제제
US20220008429A2 (en) * 2019-03-22 2022-01-13 Shionogi & Co., Ltd. Treating influenza using substituted polycyclic pyridone derivatives and prodrugs thereof in a subject having influenza and a severe influenza condition
EP3714889A1 (en) * 2019-03-29 2020-09-30 F. Hoffmann-La Roche AG Baloxavir for the prevention of transmission of influenza virus
WO2021038480A1 (en) * 2019-08-27 2021-03-04 Janssen Pharmaceuticals, Inc. Combinations for treating influenza virus
WO2021084725A1 (ja) * 2019-10-31 2021-05-06 フジデノロ株式会社 検出装置、磁気組成物、及び、管理システム
CN111647005A (zh) * 2020-06-15 2020-09-11 安徽皓元药业有限公司 巴洛沙韦新晶型及其制备方法
JP7557863B2 (ja) * 2020-10-12 2024-09-30 共和薬品工業株式会社 イストラデフィリン含有医薬組成物
CN112730682B (zh) * 2020-12-25 2022-06-17 苏州海科医药技术有限公司 一种抗病毒药物临床研究血浆样本中奥司他韦及代谢物奥司他韦酸浓度的生物分析方法
CN114306261A (zh) * 2021-12-15 2022-04-12 澳美制药(苏州)有限公司 巴洛沙韦酯片及其制备方法
CN116036035A (zh) * 2023-02-28 2023-05-02 山东诚创蓝海医药科技有限公司 一种不含二氧化钛的富马酸伏诺拉生片剂制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015054851A (ja) 2013-09-13 2015-03-23 大鵬薬品工業株式会社 被覆経口固形製剤

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2759293B1 (fr) 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
DE19831869A1 (de) * 1998-07-16 2000-01-20 Merck Patent Gmbh Farbgebung mit Perlglanzpigmenten im Lebensmittel- und Pharmabereich
KR100891887B1 (ko) 2001-01-29 2009-04-03 시오노기세이야쿠가부시키가이샤 5-메틸-1-페닐-2-(1ｈ)-피리돈을 활성 성분으로서 함유하는의약 제제
WO2003057668A1 (en) * 2001-12-28 2003-07-17 Takeda Chemical Industries, Ltd. Nitrogenous cyclic ketone derivative, process for producing the same, and use
SE0203778D0 (sv) 2002-12-09 2002-12-09 Astrazeneca Ab A new oral immediated release dosage form
WO2004091600A1 (ja) * 2003-04-16 2004-10-28 Kyorin Pharmaceutical Co., Ltd. 経口固形製剤
PT1944029E (pt) 2005-10-31 2012-02-09 Nissan Chemical Ind Ltd Preparação farmacêutica com excelente fotoestabilidade
TWI404726B (zh) * 2006-10-25 2013-08-11 Takeda Pharmaceutical 腫瘤轉移抑制素衍生物及其用途
JP2008201712A (ja) 2007-02-20 2008-09-04 Ss Pharmaceut Co Ltd フィルムコーティング製剤
WO2008114859A1 (ja) 2007-03-22 2008-09-25 Astellas Pharma Inc. ピラゾール誘導体を含有する医薬組成物
EP2320909B8 (en) 2008-07-25 2016-03-30 VIIV Healthcare Company Chemical compounds
JP5644167B2 (ja) 2009-04-21 2014-12-24 大正製薬株式会社 溶出改善されたケトチフェン又はその塩を含有する固形製剤
US20110009347A1 (en) * 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
CA2770077A1 (en) * 2009-08-06 2011-02-10 Ironwood Pharmaceuticals, Inc. Formulations comprising linaclotide
EP2590631B1 (en) * 2010-07-06 2016-10-26 Janssen Pharmaceutica NV Formulation for co-therapy treatment of diabetes
JP4803686B2 (ja) * 2010-08-31 2011-10-26 協和発酵キリン株式会社 苦味を呈する薬物を含有する顆粒および口腔内崩壊錠
CN103687596B (zh) 2011-04-22 2016-08-17 安斯泰来制药有限公司 固态医药组合物
CA2835364C (en) 2011-05-20 2018-10-02 Astrazeneca Uk Limited Pharmaceutical composition of rosuvastatin calcium
JP5553132B2 (ja) * 2011-09-30 2014-07-16 アステラス製薬株式会社 粒子状医薬組成物
US9827200B2 (en) 2012-04-24 2017-11-28 Daiichi Sankyo Company, Limited Orally disintegrating tablet and production process therefor
JP2015054822A (ja) 2013-09-10 2015-03-23 ニプロ株式会社 クロピドグレル含有錠剤およびその製造方法
CN105899232A (zh) * 2013-11-13 2016-08-24 诺华股份有限公司 用于增强免疫应答的mTOR抑制剂
US10287354B2 (en) * 2013-12-20 2019-05-14 Novartis Ag Regulatable chimeric antigen receptor
BR112017022550B1 (pt) 2015-04-28 2021-02-23 Shionogi & Co., Ltd derivados policíclicos de piridona substituída
WO2016204291A1 (ja) * 2015-06-18 2016-12-22 共同印刷株式会社 ブリスターパック用積層体、及びそれを用いたブリスターパック
AU2016374416A1 (en) * 2015-12-15 2018-06-14 Shionogi & Co., Ltd. Medicine for treating influenza characterized by comprising combination of cap-dependent endonuclease inhibitor with anti-influenza drug
KR102501180B1 (ko) 2018-04-24 2023-02-21 시오노기세야쿠 가부시키가이샤 안정성이 우수한 고형 제제

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015054851A (ja) 2013-09-13 2015-03-23 大鵬薬品工業株式会社 被覆経口固形製剤

Also Published As

Publication number Publication date
AU2018369241A1 (en) 2020-06-18
IL274625B (en) 2022-08-01
ES3058136T3 (en) 2026-03-09
US20200375998A1 (en) 2020-12-03
JP7251891B2 (ja) 2023-04-04
EP3711767B1 (en) 2025-11-12
US20240366622A1 (en) 2024-11-07
BR112020009634A2 (pt) 2020-11-10
AU2018369241B2 (en) 2023-01-05
EP3711767A4 (en) 2021-12-01
BR112020009634B1 (pt) 2022-08-30
IL274625A (en) 2020-06-30
PL3711767T3 (pl) 2026-02-16
KR20200089290A (ko) 2020-07-24
TWI795462B (zh) 2023-03-11
EP4650773A2 (en) 2025-11-19
WO2019098259A1 (ja) 2019-05-23
CA3082522A1 (en) 2019-05-23
EP3711767A1 (en) 2020-09-23
EP3711767C0 (en) 2025-11-12
EP4650773A3 (en) 2026-03-04
MX2020004680A (es) 2020-08-13
JP2020079283A (ja) 2020-05-28
AR113890A1 (es) 2020-06-24
TW201922259A (zh) 2019-06-16
CA3299815A1 (en) 2026-04-09
JP6660644B2 (ja) 2020-03-11
JPWO2019098259A1 (ja) 2019-12-12
US12064438B2 (en) 2024-08-20
CN111615390A (zh) 2020-09-01

Similar Documents

Publication Publication Date Title
KR102562514B1 (ko) 광안정성 및 용출성이 우수한 의약 제제
KR102501180B1 (ko) 안정성이 우수한 고형 제제
KR20140075754A (ko) 7-[4-(4-벤조[ｂ]티오펜-4-일-피페라진-1-일)부톡시]-1Ｈ-퀴놀린-2-온 또는 그 염을 함유하는 정제
KR102602820B1 (ko) 퀴나졸린 유도체를 함유하는 고형 제제
JP6590436B1 (ja) 安定性に優れた固形製剤
CN109475557A (zh) 含有甲氨蝶呤的薄膜包衣片
CN109232293A (zh) 芬乐胺晶g型、制备方法和其组合物与用途
CN109758431A (zh) 一种盐酸二甲双胍片及其制备方法
HK40032546A (en) Pharmaceutical preparation excellent in light stability and dissolution property
JP2019214562A (ja) 光安定性を向上させた固形状組成物
RU2543322C1 (ru) Фармацевтическая композиция для лечения вич-инфекции, способ ее получения и способ лечения
CN103965189A (zh) 一种新的盐酸莫西沙星化合物
HK40036689A (zh) 稳定性优良的固体制剂
WO2020080472A1 (ja) コーティング方法
Gada Design and Evaluation of Mouth Dissolving Tablets of Diethylcarbamazine Citrate
Raghu Formulation and evaluation of mouth dissolving tablets of pioglitazone cyclodextrin complex
JP2008162949A (ja) チアゾリジンジオン化合物を含有する糖尿病治療薬

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601