KR102530707B1 - 초휘도 이량체성 또는 중합체성 염료 - Google Patents

초휘도 이량체성 또는 중합체성 염료 Download PDF

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KR102530707B1
KR102530707B1 KR1020177019774A KR20177019774A KR102530707B1 KR 102530707 B1 KR102530707 B1 KR 102530707B1 KR 1020177019774 A KR1020177019774 A KR 1020177019774A KR 20177019774 A KR20177019774 A KR 20177019774A KR 102530707 B1 KR102530707 B1 KR 102530707B1
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KR20180132501A (ko
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트레이시 매트레이
샤랏 싱
마이클 밴브런트
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소니그룹주식회사
소니 코포레이션 오브 아메리카
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    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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    • C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • C09B69/101—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an anthracene dye
    • C09B69/102—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an anthracene dye containing a perylene dye
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/68—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
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    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
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    • C07F9/02—Phosphorus compounds
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    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
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    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/48—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
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    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

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  • Cell Biology (AREA)
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  • Plural Heterocyclic Compounds (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1020177019774A 2016-04-01 2017-03-31 초휘도 이량체성 또는 중합체성 염료 Active KR102530707B1 (ko)

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US201662317192P 2016-04-01 2016-04-01
US62/317,192 2016-04-01
PCT/US2017/025530 WO2017173355A1 (en) 2016-04-01 2017-03-31 Ultra bright dimeric or polymeric dyes

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KR1020257005807A Pending KR20250029292A (ko) 2016-04-01 2017-03-31 초휘도 이량체성 또는 중합체성 염료
KR1020177019774A Active KR102530707B1 (ko) 2016-04-01 2017-03-31 초휘도 이량체성 또는 중합체성 염료

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US (3) US11142647B2 (enExample)
EP (1) EP3436529A1 (enExample)
JP (1) JP7049113B2 (enExample)
KR (3) KR102773661B1 (enExample)
CN (2) CN107580618A (enExample)
AU (1) AU2017240154B2 (enExample)
BR (1) BR112018070164B1 (enExample)
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KR20230066652A (ko) * 2016-04-01 2023-05-16 소니그룹주식회사 초휘도 이량체성 또는 중합체성 염료
US12194104B2 (en) 2018-01-12 2025-01-14 Sony Group Corporation Phosphoalkyl ribose polymers comprising biologically active compounds
US12270812B2 (en) 2016-04-06 2025-04-08 Sony Group Corporation Ultra bright dimeric or polymeric dyes with spacing linker groups
US12275851B2 (en) 2018-03-21 2025-04-15 Sony Group Corporation Polymeric tandem dyes with linker groups
US12290571B2 (en) 2017-10-05 2025-05-06 Sony Group Corporation Programmable dendritic drugs
US12359071B2 (en) 2019-09-26 2025-07-15 Sony Group Corporation Polymeric tandem dyes with linker groups
US12391833B2 (en) 2018-06-27 2025-08-19 Sony Group Corporation Polymeric dyes with linker groups comprising deoxyribose
US12473433B2 (en) 2020-12-07 2025-11-18 Sony Group Corporation Spacing linker group design for brightness enhancement in dimeric or polymeric dyes

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KR102676814B1 (ko) 2015-02-26 2024-06-21 소니그룹주식회사 접합 그룹을 포함하는 수용성 형광 또는 착색 염료
JP6849599B2 (ja) 2015-05-11 2021-03-24 ソニー株式会社 超明色ダイマーまたはポリマー染料
WO2017173348A1 (en) 2016-04-01 2017-10-05 Sony Corporation Ultra bright dimeric or polymeric dyes with rigid spacing groups
JP7068192B2 (ja) 2016-05-10 2022-05-16 ソニーグループ株式会社 ポリマー染料およびシクロデキストリンを含む組成物、ならびにその使用
EP3455238A1 (en) 2016-05-10 2019-03-20 Sony Corporation Ultra bright polymeric dyes with peptide backbones
CA3021419A1 (en) 2016-05-11 2017-11-16 Sony Corporation Ultra bright dimeric or polymeric dyes
JP7068191B2 (ja) 2016-06-06 2022-05-16 ソニーグループ株式会社 蛍光または有色レポーター基を含むイオン性ポリマー
WO2018022925A1 (en) 2016-07-29 2018-02-01 Sony Corporation Ultra bright dimeric or polymeric dyes and methods for preparation of the same
EP4075133A3 (en) 2017-06-16 2022-11-23 Duke University Resonator networks for improved label detection, computation, analyte sensing, and tunable random number generation
KR20200067132A (ko) 2017-10-05 2020-06-11 소니 주식회사 프로그램가능한 중합체성 약물
KR20200083605A (ko) * 2017-11-16 2020-07-08 소니 주식회사 프로그램가능한 중합체성 약물
CN111565756A (zh) 2018-01-12 2020-08-21 索尼公司 包含生物活性化合物的具有刚性间隔基团的聚合物
US20200360526A1 (en) * 2018-01-12 2020-11-19 Sony Corporation Phosphoalkyl polymers comprising biologically active compounds
KR102742386B1 (ko) 2018-03-19 2024-12-16 소니그룹주식회사 형광 신호 향상을 위한 2가 금속의 사용
CN112384573A (zh) 2018-03-30 2021-02-19 贝克顿·迪金森公司 含侧基发色团的水溶性聚合染料
US20210285953A1 (en) 2018-07-13 2021-09-16 Sony Corporation Polymeric dyes having a backbone comprising organophosphate units
JP7603918B2 (ja) * 2019-04-11 2024-12-23 ソニーグループ株式会社 プログラム可能なポリマー薬
KR20220075399A (ko) * 2019-09-30 2022-06-08 소니그룹주식회사 뉴클레오티드 프로브
JP2023550791A (ja) 2020-11-25 2023-12-05 ソニーグループ株式会社 ポリマー色素
CN116917738A (zh) 2021-04-07 2023-10-20 贝克顿·迪金森公司 水溶性荧光聚合物染料
WO2023242661A2 (en) 2022-06-15 2023-12-21 Sony Group Corporation Polymeric tandem dyes with spacing linker groups
CN119546706A (zh) 2022-06-15 2025-02-28 索尼集团公司 具有间隔连接基基团的聚合物串联染料

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