KR102526906B1 - Cfdna를 이용한 유방암 진단방법 - Google Patents
Cfdna를 이용한 유방암 진단방법 Download PDFInfo
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- KR102526906B1 KR102526906B1 KR1020200041228A KR20200041228A KR102526906B1 KR 102526906 B1 KR102526906 B1 KR 102526906B1 KR 1020200041228 A KR1020200041228 A KR 1020200041228A KR 20200041228 A KR20200041228 A KR 20200041228A KR 102526906 B1 KR102526906 B1 KR 102526906B1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
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- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/101—Temperature
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/125—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being enzymatic, i.e. proteins, and non proteins, such as nucleic acid with enzymatic activity
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/131—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/155—Particles of a defined size, e.g. nanoparticles
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20190039974 | 2019-04-05 | ||
| KR1020190039974 | 2019-04-05 | ||
| KR20190157368 | 2019-11-29 | ||
| KR1020190157368 | 2019-11-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20200117912A KR20200117912A (ko) | 2020-10-14 |
| KR102526906B1 true KR102526906B1 (ko) | 2023-05-02 |
Family
ID=72666861
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020200041228A Active KR102526906B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 유방암 진단방법 |
| KR1020200041220A Active KR102745852B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 전립선암 진단방법 |
| KR1020200041243A Active KR102745906B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 췌장암 진단방법 |
| KR1020200041245A Active KR102745908B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 암 진단방법 |
| KR1020200041230A Active KR102526913B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 대장암 진단방법 |
| KR1020200041223A Active KR102372425B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 폐암 진단방법 |
| KR1020200041226A Active KR102745889B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 갑상선암 진단방법 |
| KR1020200041227A Active KR102745894B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 방광암 진단방법 |
| KR1020200041239A Active KR102526916B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 위암 진단방법 |
| KR1020200041233A Active KR102745900B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 담도암 진단방법 |
Family Applications After (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020200041220A Active KR102745852B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 전립선암 진단방법 |
| KR1020200041243A Active KR102745906B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 췌장암 진단방법 |
| KR1020200041245A Active KR102745908B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 암 진단방법 |
| KR1020200041230A Active KR102526913B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 대장암 진단방법 |
| KR1020200041223A Active KR102372425B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 폐암 진단방법 |
| KR1020200041226A Active KR102745889B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 갑상선암 진단방법 |
| KR1020200041227A Active KR102745894B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 방광암 진단방법 |
| KR1020200041239A Active KR102526916B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 위암 진단방법 |
| KR1020200041233A Active KR102745900B1 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 담도암 진단방법 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220170108A1 (enExample) |
| EP (1) | EP3950962A4 (enExample) |
| JP (2) | JP7782835B2 (enExample) |
| KR (10) | KR102526906B1 (enExample) |
| CN (1) | CN113677808A (enExample) |
| TW (1) | TW202104598A (enExample) |
| WO (1) | WO2020204674A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2627085B (en) | 2019-11-06 | 2024-11-13 | Univ Leland Stanford Junior | Methods and systems for analysing nucleic acid molecules |
| WO2022203093A1 (ko) * | 2021-03-22 | 2022-09-29 | 이원다이애그노믹스(주) | 암 발생여부를 진단 또는 예측하는 방법 |
| US11783912B2 (en) | 2021-05-05 | 2023-10-10 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and systems for analyzing nucleic acid molecules |
| CN113718031B (zh) * | 2021-08-17 | 2022-05-20 | 浙江大学医学院附属妇产科医院 | 一种卵巢癌早期诊断组合物的建立 |
| CN116219012A (zh) * | 2022-12-15 | 2023-06-06 | 华中科技大学同济医学院附属同济医院 | 基于血浆cfDNA片段分布特征预测宫颈癌新辅助化疗效果或复发高危分类的系统及方法 |
| KR20250030880A (ko) | 2023-08-25 | 2025-03-05 | 경상국립대학교병원 | 폐암 치료 예후 예측을 위한 정보제공방법 및 폐암 치료 예후 예측용 조성물 |
| KR20250074714A (ko) * | 2023-11-15 | 2025-05-28 | 주식회사 진캐스트 | Rna를 이용한 폐암 변이 유전자의 대규모 다중 검출 방법 및 이를 이용한 폐암 변이 유전자의 대규모 다중 검출 키트 |
| WO2025127193A1 (ko) * | 2023-12-13 | 2025-06-19 | 연세대학교 산학협력단 | 높은 sfrp4의 발현을 보이는 암의 치료방법 |
| WO2025213150A1 (en) * | 2024-04-06 | 2025-10-09 | Precede Biosciences, Inc. | Methods, kits and systems for measuring psa and psma expression and methods for treating cancer based on same |
| CN118497344A (zh) * | 2024-05-11 | 2024-08-16 | 青岛可立生物医药有限公司 | 用于结直肠癌诊断及分型的生物标志物及筛选方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070044048A (ko) * | 2004-08-11 | 2007-04-26 | 더 클리브랜드 클리닉 파운데이션 | 갑상선암의 검출방법 |
| US9315802B2 (en) * | 2009-12-30 | 2016-04-19 | Quest Diagnostics Investments Incorporated | RNA isolation from soluble urine fractions |
| EP3218523B1 (en) * | 2014-11-14 | 2020-02-12 | Liquid Genomics Inc. | Use of circulating cell-free rna for diagnosis and/or monitoring cancer |
| WO2016145323A1 (en) * | 2015-03-11 | 2016-09-15 | The Governing Council Of The University Of Toronto | An electrochemical clamp assay |
| MA45480A (fr) * | 2015-03-12 | 2018-01-17 | Janssen Pharmaceutica Nv | Marqueurs d'arnm à base de sang total pour prédire un cancer de la prostate, et leurs procédés de détection |
| KR101751962B1 (ko) | 2015-04-30 | 2017-06-30 | 주식회사 넥스바이오 | 세포-유리형 dna의 위암 진단 용도 |
| KR101701618B1 (ko) * | 2015-06-23 | 2017-02-13 | 국립암센터 | 전도성 고분자를 이용한 세포 유리 dna 검출용 구조체 및 이의 용도 |
| US11149299B2 (en) * | 2015-06-25 | 2021-10-19 | Ramesh Vallabhaneni | Method and system for multiplex profiling of chromosomes in biological samples using target-specific DNA probes |
| KR20170124683A (ko) * | 2016-05-02 | 2017-11-13 | 연세대학교 산학협력단 | 담도암 진단용 신규 바이오마커로서의 융합 유전자 및 융합 단백질 |
| KR101925125B1 (ko) | 2016-06-16 | 2018-12-04 | 울산대학교 산학협력단 | Nckap1을 유효성분으로 포함하는 대장암 진단 또는 대장암 전이 예후 예측용 바이오마커 조성물 |
| KR101818352B1 (ko) * | 2016-06-30 | 2018-01-15 | 충북대학교 산학협력단 | 방광암의 진단 및 예후 예측용 바이오 마커 및 그의 용도 |
| KR101980819B1 (ko) * | 2016-12-23 | 2019-05-21 | 주식회사 제놉시 | 자성 나노 입자가 탑재된 전도성 고분자 및 양이온성 고분자를 포함하는 세포-유리(cell-free) DNA 검출 및 회수용 자성 나노 구조체 |
| US10870891B2 (en) * | 2017-01-05 | 2020-12-22 | Biodesix, Inc. | Diagnostic test system for specific, sensitive and reproducible detection of circulating nucleic acids in whole blood |
| KR20200003917A (ko) * | 2017-05-10 | 2020-01-10 | 난토믹스, 엘엘씨 | 암의 검출, 예측, 및 모니터링을 위한 순환 rna(circulating rna for detection, prediction, and monitoring of cancer) |
| CN107164543A (zh) | 2017-06-16 | 2017-09-15 | 上海长海医院 | Kras 作为胰腺癌中生物标志物的用途 |
| JP2021526029A (ja) * | 2018-06-01 | 2021-09-30 | ジェノプシー・カンパニー・リミテッドGenopsy Co., Ltd. | 不安定セルフリーdnaを検出する方法およびそれを使用するデバイス |
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2020
- 2020-04-03 KR KR1020200041228A patent/KR102526906B1/ko active Active
- 2020-04-03 KR KR1020200041220A patent/KR102745852B1/ko active Active
- 2020-04-03 KR KR1020200041243A patent/KR102745906B1/ko active Active
- 2020-04-03 KR KR1020200041245A patent/KR102745908B1/ko active Active
- 2020-04-03 KR KR1020200041230A patent/KR102526913B1/ko active Active
- 2020-04-03 US US17/594,063 patent/US20220170108A1/en active Pending
- 2020-04-03 KR KR1020200041223A patent/KR102372425B1/ko active Active
- 2020-04-03 KR KR1020200041226A patent/KR102745889B1/ko active Active
- 2020-04-03 JP JP2021560412A patent/JP7782835B2/ja active Active
- 2020-04-03 CN CN202080027434.4A patent/CN113677808A/zh active Pending
- 2020-04-03 EP EP20782477.2A patent/EP3950962A4/en active Pending
- 2020-04-03 KR KR1020200041227A patent/KR102745894B1/ko active Active
- 2020-04-03 WO PCT/KR2020/004602 patent/WO2020204674A2/ko not_active Ceased
- 2020-04-03 KR KR1020200041239A patent/KR102526916B1/ko active Active
- 2020-04-03 KR KR1020200041233A patent/KR102745900B1/ko active Active
- 2020-04-06 TW TW109111543A patent/TW202104598A/zh unknown
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2025
- 2025-10-24 JP JP2025179760A patent/JP2026021394A/ja active Pending
Non-Patent Citations (2)
| Title |
|---|
| Appl Cancer Res, 38: 4 (2018.01.24.)* |
| Theranostics, 8(2): 399-409 (2018.01.01.).* |
Also Published As
| Publication number | Publication date |
|---|---|
| KR102745889B1 (ko) | 2024-12-23 |
| KR20200117914A (ko) | 2020-10-14 |
| KR20200117907A (ko) | 2020-10-14 |
| KR20200117912A (ko) | 2020-10-14 |
| KR102745852B1 (ko) | 2024-12-23 |
| WO2020204674A2 (ko) | 2020-10-08 |
| US20220170108A1 (en) | 2022-06-02 |
| KR102372425B1 (ko) | 2022-03-10 |
| KR102745908B1 (ko) | 2024-12-23 |
| KR102526913B1 (ko) | 2023-05-02 |
| WO2020204674A3 (ko) | 2020-12-17 |
| JP2026021394A (ja) | 2026-02-10 |
| EP3950962A2 (en) | 2022-02-09 |
| KR20200117915A (ko) | 2020-10-14 |
| KR20200117909A (ko) | 2020-10-14 |
| KR102745906B1 (ko) | 2024-12-23 |
| CN113677808A (zh) | 2021-11-19 |
| TW202104598A (zh) | 2021-02-01 |
| KR20200117911A (ko) | 2020-10-14 |
| KR102745894B1 (ko) | 2024-12-23 |
| KR102745900B1 (ko) | 2024-12-23 |
| KR20200117913A (ko) | 2020-10-14 |
| JP2022528278A (ja) | 2022-06-09 |
| KR102526916B1 (ko) | 2023-05-02 |
| JP7782835B2 (ja) | 2025-12-09 |
| EP3950962A4 (en) | 2023-01-11 |
| KR20200117917A (ko) | 2020-10-14 |
| KR20200117916A (ko) | 2020-10-14 |
| KR20200117910A (ko) | 2020-10-14 |
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