CN113677808A - 用于使用cfDNA诊断癌症的方法 - Google Patents
用于使用cfDNA诊断癌症的方法 Download PDFInfo
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- CN113677808A CN113677808A CN202080027434.4A CN202080027434A CN113677808A CN 113677808 A CN113677808 A CN 113677808A CN 202080027434 A CN202080027434 A CN 202080027434A CN 113677808 A CN113677808 A CN 113677808A
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/125—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being enzymatic, i.e. proteins, and non proteins, such as nucleic acid with enzymatic activity
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/131—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/155—Particles of a defined size, e.g. nanoparticles
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Proteomics, Peptides & Aminoacids (AREA)
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- Wood Science & Technology (AREA)
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- Genetics & Genomics (AREA)
- Immunology (AREA)
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- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20190039974 | 2019-04-05 | ||
| KR10-2019-0039974 | 2019-04-05 | ||
| KR20190157368 | 2019-11-29 | ||
| KR10-2019-0157368 | 2019-11-29 | ||
| PCT/KR2020/004602 WO2020204674A2 (ko) | 2019-04-05 | 2020-04-03 | Cfdna를 이용한 암 진단방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113677808A true CN113677808A (zh) | 2021-11-19 |
Family
ID=72666861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080027434.4A Pending CN113677808A (zh) | 2019-04-05 | 2020-04-03 | 用于使用cfDNA诊断癌症的方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220170108A1 (enExample) |
| EP (1) | EP3950962A4 (enExample) |
| JP (2) | JP7782835B2 (enExample) |
| KR (10) | KR102526906B1 (enExample) |
| CN (1) | CN113677808A (enExample) |
| TW (1) | TW202104598A (enExample) |
| WO (1) | WO2020204674A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116219012A (zh) * | 2022-12-15 | 2023-06-06 | 华中科技大学同济医学院附属同济医院 | 基于血浆cfDNA片段分布特征预测宫颈癌新辅助化疗效果或复发高危分类的系统及方法 |
| CN118497344A (zh) * | 2024-05-11 | 2024-08-16 | 青岛可立生物医药有限公司 | 用于结直肠癌诊断及分型的生物标志物及筛选方法 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2627085B (en) | 2019-11-06 | 2024-11-13 | Univ Leland Stanford Junior | Methods and systems for analysing nucleic acid molecules |
| WO2022203093A1 (ko) * | 2021-03-22 | 2022-09-29 | 이원다이애그노믹스(주) | 암 발생여부를 진단 또는 예측하는 방법 |
| US11783912B2 (en) | 2021-05-05 | 2023-10-10 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and systems for analyzing nucleic acid molecules |
| CN113718031B (zh) * | 2021-08-17 | 2022-05-20 | 浙江大学医学院附属妇产科医院 | 一种卵巢癌早期诊断组合物的建立 |
| KR20250030880A (ko) | 2023-08-25 | 2025-03-05 | 경상국립대학교병원 | 폐암 치료 예후 예측을 위한 정보제공방법 및 폐암 치료 예후 예측용 조성물 |
| KR20250074714A (ko) * | 2023-11-15 | 2025-05-28 | 주식회사 진캐스트 | Rna를 이용한 폐암 변이 유전자의 대규모 다중 검출 방법 및 이를 이용한 폐암 변이 유전자의 대규모 다중 검출 키트 |
| WO2025127193A1 (ko) * | 2023-12-13 | 2025-06-19 | 연세대학교 산학협력단 | 높은 sfrp4의 발현을 보이는 암의 치료방법 |
| WO2025213150A1 (en) * | 2024-04-06 | 2025-10-09 | Precede Biosciences, Inc. | Methods, kits and systems for measuring psa and psma expression and methods for treating cancer based on same |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107709578A (zh) * | 2015-06-25 | 2018-02-16 | 拉梅什·瓦拉巴恩尼 | 使用靶向特异性dna探针在生物样品中进行染色体多重分析的方法和系统 |
| CN107980061A (zh) * | 2015-06-23 | 2018-05-01 | 国立癌症中心 | 使用导电聚合物的游离dna捕获平台以及该平台的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070044048A (ko) * | 2004-08-11 | 2007-04-26 | 더 클리브랜드 클리닉 파운데이션 | 갑상선암의 검출방법 |
| US9315802B2 (en) * | 2009-12-30 | 2016-04-19 | Quest Diagnostics Investments Incorporated | RNA isolation from soluble urine fractions |
| EP3218523B1 (en) * | 2014-11-14 | 2020-02-12 | Liquid Genomics Inc. | Use of circulating cell-free rna for diagnosis and/or monitoring cancer |
| WO2016145323A1 (en) * | 2015-03-11 | 2016-09-15 | The Governing Council Of The University Of Toronto | An electrochemical clamp assay |
| MA45480A (fr) * | 2015-03-12 | 2018-01-17 | Janssen Pharmaceutica Nv | Marqueurs d'arnm à base de sang total pour prédire un cancer de la prostate, et leurs procédés de détection |
| KR101751962B1 (ko) | 2015-04-30 | 2017-06-30 | 주식회사 넥스바이오 | 세포-유리형 dna의 위암 진단 용도 |
| KR20170124683A (ko) * | 2016-05-02 | 2017-11-13 | 연세대학교 산학협력단 | 담도암 진단용 신규 바이오마커로서의 융합 유전자 및 융합 단백질 |
| KR101925125B1 (ko) | 2016-06-16 | 2018-12-04 | 울산대학교 산학협력단 | Nckap1을 유효성분으로 포함하는 대장암 진단 또는 대장암 전이 예후 예측용 바이오마커 조성물 |
| KR101818352B1 (ko) * | 2016-06-30 | 2018-01-15 | 충북대학교 산학협력단 | 방광암의 진단 및 예후 예측용 바이오 마커 및 그의 용도 |
| KR101980819B1 (ko) * | 2016-12-23 | 2019-05-21 | 주식회사 제놉시 | 자성 나노 입자가 탑재된 전도성 고분자 및 양이온성 고분자를 포함하는 세포-유리(cell-free) DNA 검출 및 회수용 자성 나노 구조체 |
| US10870891B2 (en) * | 2017-01-05 | 2020-12-22 | Biodesix, Inc. | Diagnostic test system for specific, sensitive and reproducible detection of circulating nucleic acids in whole blood |
| KR20200003917A (ko) * | 2017-05-10 | 2020-01-10 | 난토믹스, 엘엘씨 | 암의 검출, 예측, 및 모니터링을 위한 순환 rna(circulating rna for detection, prediction, and monitoring of cancer) |
| CN107164543A (zh) | 2017-06-16 | 2017-09-15 | 上海长海医院 | Kras 作为胰腺癌中生物标志物的用途 |
| JP2021526029A (ja) * | 2018-06-01 | 2021-09-30 | ジェノプシー・カンパニー・リミテッドGenopsy Co., Ltd. | 不安定セルフリーdnaを検出する方法およびそれを使用するデバイス |
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2020
- 2020-04-03 KR KR1020200041228A patent/KR102526906B1/ko active Active
- 2020-04-03 KR KR1020200041220A patent/KR102745852B1/ko active Active
- 2020-04-03 KR KR1020200041243A patent/KR102745906B1/ko active Active
- 2020-04-03 KR KR1020200041245A patent/KR102745908B1/ko active Active
- 2020-04-03 KR KR1020200041230A patent/KR102526913B1/ko active Active
- 2020-04-03 US US17/594,063 patent/US20220170108A1/en active Pending
- 2020-04-03 KR KR1020200041223A patent/KR102372425B1/ko active Active
- 2020-04-03 KR KR1020200041226A patent/KR102745889B1/ko active Active
- 2020-04-03 JP JP2021560412A patent/JP7782835B2/ja active Active
- 2020-04-03 CN CN202080027434.4A patent/CN113677808A/zh active Pending
- 2020-04-03 EP EP20782477.2A patent/EP3950962A4/en active Pending
- 2020-04-03 KR KR1020200041227A patent/KR102745894B1/ko active Active
- 2020-04-03 WO PCT/KR2020/004602 patent/WO2020204674A2/ko not_active Ceased
- 2020-04-03 KR KR1020200041239A patent/KR102526916B1/ko active Active
- 2020-04-03 KR KR1020200041233A patent/KR102745900B1/ko active Active
- 2020-04-06 TW TW109111543A patent/TW202104598A/zh unknown
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2025
- 2025-10-24 JP JP2025179760A patent/JP2026021394A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107980061A (zh) * | 2015-06-23 | 2018-05-01 | 国立癌症中心 | 使用导电聚合物的游离dna捕获平台以及该平台的应用 |
| CN107709578A (zh) * | 2015-06-25 | 2018-02-16 | 拉梅什·瓦拉巴恩尼 | 使用靶向特异性dna探针在生物样品中进行染色体多重分析的方法和系统 |
Non-Patent Citations (3)
| Title |
|---|
| JAGOTAMOY DAS等: ""An electrochemical clamp assay for direct, rapid analysis of circulating nucleic acids in serum"", 《NATURE CHEMISTRY》, vol. 7, 1 June 2015 (2015-06-01), pages 573 - 574 * |
| 陈晓光: "《药理学研究的新技术与新方法》", vol. 1, 31 March 2014, 中国协和医科大学出版社, pages: 188 * |
| 陈英: "《精神疾病的分子生物学与遗传研究》", vol. 1, 31 March 2015, 科学技术文献出版社, pages: 171 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116219012A (zh) * | 2022-12-15 | 2023-06-06 | 华中科技大学同济医学院附属同济医院 | 基于血浆cfDNA片段分布特征预测宫颈癌新辅助化疗效果或复发高危分类的系统及方法 |
| CN118497344A (zh) * | 2024-05-11 | 2024-08-16 | 青岛可立生物医药有限公司 | 用于结直肠癌诊断及分型的生物标志物及筛选方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR102745889B1 (ko) | 2024-12-23 |
| KR20200117914A (ko) | 2020-10-14 |
| KR20200117907A (ko) | 2020-10-14 |
| KR20200117912A (ko) | 2020-10-14 |
| KR102745852B1 (ko) | 2024-12-23 |
| WO2020204674A2 (ko) | 2020-10-08 |
| US20220170108A1 (en) | 2022-06-02 |
| KR102372425B1 (ko) | 2022-03-10 |
| KR102745908B1 (ko) | 2024-12-23 |
| KR102526913B1 (ko) | 2023-05-02 |
| WO2020204674A3 (ko) | 2020-12-17 |
| JP2026021394A (ja) | 2026-02-10 |
| KR102526906B1 (ko) | 2023-05-02 |
| EP3950962A2 (en) | 2022-02-09 |
| KR20200117915A (ko) | 2020-10-14 |
| KR20200117909A (ko) | 2020-10-14 |
| KR102745906B1 (ko) | 2024-12-23 |
| TW202104598A (zh) | 2021-02-01 |
| KR20200117911A (ko) | 2020-10-14 |
| KR102745894B1 (ko) | 2024-12-23 |
| KR102745900B1 (ko) | 2024-12-23 |
| KR20200117913A (ko) | 2020-10-14 |
| JP2022528278A (ja) | 2022-06-09 |
| KR102526916B1 (ko) | 2023-05-02 |
| JP7782835B2 (ja) | 2025-12-09 |
| EP3950962A4 (en) | 2023-01-11 |
| KR20200117917A (ko) | 2020-10-14 |
| KR20200117916A (ko) | 2020-10-14 |
| KR20200117910A (ko) | 2020-10-14 |
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