JP7782835B2 - Ｃｆｄｎａを用いたがん診断方法 - Google Patents

Ｃｆｄｎａを用いたがん診断方法

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Publication number
JP7782835B2
JP7782835B2 JP2021560412A JP2021560412A JP7782835B2 JP 7782835 B2 JP7782835 B2 JP 7782835B2 JP 2021560412 A JP2021560412 A JP 2021560412A JP 2021560412 A JP2021560412 A JP 2021560412A JP 7782835 B2 JP7782835 B2 JP 7782835B2
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cfdna
cancer
marker
probe
gene
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JP2022528278A5 (enExample
JP2022528278A (ja
Inventor
チョ、ヨンナム
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Genopsy Co Ltd
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Genopsy Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/101—Temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/125—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being enzymatic, i.e. proteins, and non proteins, such as nucleic acid with enzymatic activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/131—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/155—Particles of a defined size, e.g. nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2021560412A 2019-04-05 2020-04-03 Ｃｆｄｎａを用いたがん診断方法 Active JP7782835B2 (ja)

Priority Applications (1)

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JP2025179760A JP2026021394A (ja) 2019-04-05 2025-10-24 Ｃｆｄｎａを用いたがん診断方法

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KR20190039974 2019-04-05
KR10-2019-0039974 2019-04-05
KR20190157368 2019-11-29
KR10-2019-0157368 2019-11-29
PCT/KR2020/004602 WO2020204674A2 (ko) 2019-04-05 2020-04-03 Cfdna를 이용한 암 진단방법

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JP7782835B2 true JP7782835B2 (ja) 2025-12-09

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US (1) US20220170108A1 (enExample)
EP (1) EP3950962A4 (enExample)
JP (2) JP7782835B2 (enExample)
KR (10) KR102526906B1 (enExample)
CN (1) CN113677808A (enExample)
TW (1) TW202104598A (enExample)
WO (1) WO2020204674A2 (enExample)

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GB2627085B (en) 2019-11-06 2024-11-13 Univ Leland Stanford Junior Methods and systems for analysing nucleic acid molecules
WO2022203093A1 (ko) * 2021-03-22 2022-09-29 이원다이애그노믹스(주) 암 발생여부를 진단 또는 예측하는 방법
US11783912B2 (en) 2021-05-05 2023-10-10 The Board Of Trustees Of The Leland Stanford Junior University Methods and systems for analyzing nucleic acid molecules
CN113718031B (zh) * 2021-08-17 2022-05-20 浙江大学医学院附属妇产科医院 一种卵巢癌早期诊断组合物的建立
CN116219012A (zh) * 2022-12-15 2023-06-06 华中科技大学同济医学院附属同济医院 基于血浆cfDNA片段分布特征预测宫颈癌新辅助化疗效果或复发高危分类的系统及方法
KR20250030880A (ko) 2023-08-25 2025-03-05 경상국립대학교병원 폐암 치료 예후 예측을 위한 정보제공방법 및 폐암 치료 예후 예측용 조성물
KR20250074714A (ko) * 2023-11-15 2025-05-28 주식회사 진캐스트 Rna를 이용한 폐암 변이 유전자의 대규모 다중 검출 방법 및 이를 이용한 폐암 변이 유전자의 대규모 다중 검출 키트
WO2025127193A1 (ko) * 2023-12-13 2025-06-19 연세대학교 산학협력단 높은 sfrp4의 발현을 보이는 암의 치료방법
WO2025213150A1 (en) * 2024-04-06 2025-10-09 Precede Biosciences, Inc. Methods, kits and systems for measuring psa and psma expression and methods for treating cancer based on same
CN118497344A (zh) * 2024-05-11 2024-08-16 青岛可立生物医药有限公司 用于结直肠癌诊断及分型的生物标志物及筛选方法

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Also Published As

Publication number Publication date
KR102745889B1 (ko) 2024-12-23
KR20200117914A (ko) 2020-10-14
KR20200117907A (ko) 2020-10-14
KR20200117912A (ko) 2020-10-14
KR102745852B1 (ko) 2024-12-23
WO2020204674A2 (ko) 2020-10-08
US20220170108A1 (en) 2022-06-02
KR102372425B1 (ko) 2022-03-10
KR102745908B1 (ko) 2024-12-23
KR102526913B1 (ko) 2023-05-02
WO2020204674A3 (ko) 2020-12-17
JP2026021394A (ja) 2026-02-10
KR102526906B1 (ko) 2023-05-02
EP3950962A2 (en) 2022-02-09
KR20200117915A (ko) 2020-10-14
KR20200117909A (ko) 2020-10-14
KR102745906B1 (ko) 2024-12-23
CN113677808A (zh) 2021-11-19
TW202104598A (zh) 2021-02-01
KR20200117911A (ko) 2020-10-14
KR102745894B1 (ko) 2024-12-23
KR102745900B1 (ko) 2024-12-23
KR20200117913A (ko) 2020-10-14
JP2022528278A (ja) 2022-06-09
KR102526916B1 (ko) 2023-05-02
EP3950962A4 (en) 2023-01-11
KR20200117917A (ko) 2020-10-14
KR20200117916A (ko) 2020-10-14
KR20200117910A (ko) 2020-10-14

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