KR102522263B1 - polX 패밀리의 DNA 폴리머라제의 변형체 - Google Patents

polX 패밀리의 DNA 폴리머라제의 변형체 Download PDF

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KR102522263B1
KR102522263B1 KR1020187034921A KR20187034921A KR102522263B1 KR 102522263 B1 KR102522263 B1 KR 102522263B1 KR 1020187034921 A KR1020187034921 A KR 1020187034921A KR 20187034921 A KR20187034921 A KR 20187034921A KR 102522263 B1 KR102522263 B1 KR 102522263B1
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KR20190024883A (ko
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토마스 이버트
마크 델라뤼
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디엔에이 스크립트
앵스티띠 파스퇴르
상뜨로 나쇼날 드 라 러쉐르쉐 샹띠피크
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1264—DNA nucleotidylexotransferase (2.7.7.31), i.e. terminal nucleotidyl transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07031—DNA nucleotidylexotransferase (2.7.7.31), i.e. terminal deoxynucleotidyl transferase

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020187034921A 2016-06-14 2017-06-13 polX 패밀리의 DNA 폴리머라제의 변형체 Active KR102522263B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1655475A FR3052462A1 (fr) 2016-06-14 2016-06-14 Variants d'une adn polymerase de la famille polx
FR1655475 2016-06-14
PCT/FR2017/051519 WO2017216472A2 (fr) 2016-06-14 2017-06-13 Variants d'une adn polymérase de la famille polx

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KR20190024883A KR20190024883A (ko) 2019-03-08
KR102522263B1 true KR102522263B1 (ko) 2023-04-18

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US (3) US20200002690A1 (enExample)
EP (1) EP3469075A2 (enExample)
JP (2) JP7118510B2 (enExample)
KR (1) KR102522263B1 (enExample)
CN (1) CN109477080A (enExample)
AU (2) AU2017286477C1 (enExample)
CA (1) CA3024184A1 (enExample)
FR (2) FR3052462A1 (enExample)
IL (1) IL263503B2 (enExample)
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JP7118510B2 (ja) 2022-08-16
JP2019517799A (ja) 2019-06-27
WO2017216472A3 (fr) 2018-03-15
WO2017216472A2 (fr) 2017-12-21
IL263503B1 (en) 2024-12-01
SG11201809961TA (en) 2018-12-28
FR3053699A1 (fr) 2018-01-12
FR3052462A1 (fr) 2017-12-15
SG10202009688QA (en) 2020-11-27
EP3469075A2 (fr) 2019-04-17
JP2022137127A (ja) 2022-09-21
IL263503A (en) 2019-02-03
CA3024184A1 (en) 2017-12-21
CN109477080A (zh) 2019-03-15
US20230167421A1 (en) 2023-06-01
AU2023282219A1 (en) 2024-01-18
IL263503B2 (en) 2025-04-01
US20240124855A1 (en) 2024-04-18
AU2017286477B2 (en) 2023-09-14
FR3053699B1 (fr) 2021-04-02
US20200002690A1 (en) 2020-01-02
KR20190024883A (ko) 2019-03-08
AU2017286477C1 (en) 2023-12-21
AU2017286477A1 (en) 2018-12-06

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