KR102515760B1 - 펩타이드 핵산 단량체와 소중합체 - Google Patents

펩타이드 핵산 단량체와 소중합체 Download PDF

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KR102515760B1
KR102515760B1 KR1020167035152A KR20167035152A KR102515760B1 KR 102515760 B1 KR102515760 B1 KR 102515760B1 KR 1020167035152 A KR1020167035152 A KR 1020167035152A KR 20167035152 A KR20167035152 A KR 20167035152A KR 102515760 B1 KR102515760 B1 KR 102515760B1
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flupac
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guaninyl
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KR20170002649A (ko
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토마스 린드호스트
비르기트 베르너
홀거 보크
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우기센스 아게
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
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KR1020167035152A 2014-05-16 2015-05-15 펩타이드 핵산 단량체와 소중합체 Active KR102515760B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102014007158.8A DE102014007158A1 (de) 2014-05-16 2014-05-16 Neue Peptid-Nukleinsäuren-Monomere und -Oligomere
DE102014007158.8 2014-05-16
PCT/EP2015/000998 WO2015172889A1 (de) 2014-05-16 2015-05-15 Peptid-nukleinsäuren-monomere und -oligomere

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KR20170002649A KR20170002649A (ko) 2017-01-06
KR102515760B1 true KR102515760B1 (ko) 2023-03-29

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US (1) US20170166900A1 (https=)
EP (1) EP3143038B8 (https=)
JP (1) JP6546272B2 (https=)
KR (1) KR102515760B1 (https=)
CN (1) CN107074911B (https=)
AU (1) AU2015258476B2 (https=)
CA (1) CA2949185C (https=)
DE (1) DE102014007158A1 (https=)
DK (1) DK3143038T3 (https=)
ES (1) ES2683186T3 (https=)
PL (1) PL3143038T3 (https=)
RU (1) RU2693827C2 (https=)
WO (1) WO2015172889A1 (https=)

Families Citing this family (7)

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Publication number Priority date Publication date Assignee Title
IL266690B2 (en) * 2016-11-16 2024-06-01 Biomarin Tech Bv Substances for targeting various selected organs or tissues
AU2018240467B2 (en) * 2017-03-23 2022-09-15 Neubase Therapeutics, Inc. Peptide nucleic acid (PNA) monomers with an orthogonally protected ester moiety
WO2020124017A2 (en) * 2018-12-13 2020-06-18 Trucode Gene Repair, Inc. Pna oligomers and related methods
EP3914261A4 (en) * 2019-01-22 2023-06-28 Korro Bio, Inc. Rna-editing oligonucleotides and uses thereof
KR20210129646A (ko) 2019-01-22 2021-10-28 코로 바이오, 인크. Rna-편집 올리고뉴클레오타이드 및 그의 용도
TW202043469A (zh) 2019-01-22 2020-12-01 美商科羅生物公司 Ｒｎａ編輯之寡核苷酸及其用途
KR102403904B1 (ko) * 2019-12-24 2022-06-02 주식회사 시선바이오머티리얼스 용액공정상 pna 올리고머의 제조방법

Citations (2)

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WO2008009470A1 (de) 2006-07-21 2008-01-24 Ugichem Gmbh Chirale mit phosphonsäureester- oder phosphonsäure- substituierte verbindungen
WO2008049583A2 (de) 2006-10-24 2008-05-02 Ugichem Gesellschaft für Organische Chemie mbH Verfahren zur selektiven lokalisierung von wirkstoffen an und in mitochondrien und entsprechende wirkstoffe

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US5719262A (en) * 1993-11-22 1998-02-17 Buchardt, Deceased; Ole Peptide nucleic acids having amino acid side chains
UA48150C2 (uk) * 1994-11-02 2002-08-15 Ай-Сі-Ен Фармасьютикалз Похідні амінокислот або аміноспиртів, олігонуклеотид
JP3306073B2 (ja) * 1996-07-24 2002-07-24 ブヒャルト，ドルテ 増加した結合親和性、配列特異性および溶解性を有するペプチド核酸
IL133087A0 (en) * 1997-05-28 2001-03-19 Nielsen Peter E Conjugated peptide nucleic acids having enhanced cellular uptake
DE19909373A1 (de) * 1999-03-03 2000-10-05 Ugichem Neue PNA-Monomere, daraus resultierende PNA-Oligomere und deren Verwendung
US8575305B2 (en) * 2008-06-04 2013-11-05 Medical Research Council Cell penetrating peptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008009470A1 (de) 2006-07-21 2008-01-24 Ugichem Gmbh Chirale mit phosphonsäureester- oder phosphonsäure- substituierte verbindungen
WO2008049583A2 (de) 2006-10-24 2008-05-02 Ugichem Gesellschaft für Organische Chemie mbH Verfahren zur selektiven lokalisierung von wirkstoffen an und in mitochondrien und entsprechende wirkstoffe
JP2010507607A (ja) * 2006-10-24 2010-03-11 ウギヘム ゲゼルシャフト フュア オルガニシェ ヘミー エムベーハー ミトコンドリアの表面および内部における活性剤の選択的局在化法ならびに相当する活性剤

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RU2016149427A3 (https=) 2018-12-05
JP2017518363A (ja) 2017-07-06
EP3143038B1 (de) 2018-08-01
AU2015258476A1 (en) 2016-12-01
DK3143038T3 (en) 2018-11-26
EP3143038A1 (de) 2017-03-22
EP3143038B8 (de) 2018-09-12
ES2683186T3 (es) 2018-09-25
WO2015172889A1 (de) 2015-11-19
KR20170002649A (ko) 2017-01-06
CN107074911B (zh) 2020-11-03
RU2693827C2 (ru) 2019-07-05
AU2015258476B2 (en) 2018-12-20
CA2949185C (en) 2023-03-14
RU2016149427A (ru) 2018-06-20
US20170166900A1 (en) 2017-06-15
CA2949185A1 (en) 2015-11-19
CN107074911A (zh) 2017-08-18
PL3143038T3 (pl) 2019-01-31
JP6546272B2 (ja) 2019-07-17
DE102014007158A1 (de) 2015-11-19

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