KR102438804B1 - Body lotion composition manufactured using ginseng oil and frankinsense oil to improve anti-wrinkles and prevent skin aging and manufacturing methods thereof - Google Patents

Abstract

The present invention relates to a body lotion composition manufactured using ginseng oil and frankincense oil to alleviate wrinkles and prevent skin aging, and to a manufacturing method thereof, and specifically, to a body lotion composition manufactured using ginseng oil and frankincense oil, and to a manufacturing method thereof, wherein the body lotion composition has no skin toxicity by using the ginseng oil and frankincense oil, which are natural products, can alleviate wrinkles by promoting collagen synthesis in the skin, and can prevent skin aging by inhibiting photo-aging caused by UV rays.

Description

Body lotion composition manufactured using ginseng oil and frankinsense oil to improve anti-wrinkles and prevent skin aging and manufacturing methods it}

The present invention relates to a body lotion composition prepared using ginseng oil and frankincense oil for wrinkle improvement and skin aging prevention, and a method for preparing the same, and in particular, skin toxicity using natural ginseng oil and frankincense oil A body lotion composition prepared using ginseng oil and frankincense oil, which can improve wrinkles by promoting collagen synthesis in the skin and prevent skin aging by inhibiting photoaging by ultraviolet rays, and a method for manufacturing the same will be.

The skin is the primary organ of aging, and the rate and degree of skin aging vary depending on several factors, such as genetic factors, exposure to UV rays, and increase in the production of various free radicals and oxidative free radicals due to physical/chemical stress. appear. Specifically, UV rays are divided into UV-A, UV-B, and UV-C according to the wavelength region. Among them, UV-B wavelength UV rays cause pigmentation such as spots and age spots on the skin. In addition, ultraviolet rays form active oxygen in the skin cells, and the various active oxygen generated accordingly damage intracellular proteins, lipids or nucleic acids, or decrease the amount of collagen synthesis, increase the amount of melanin synthesis, and metalloproteinase ( Matrix metalloproteinases (MMPs) increase gene expression to decompose extra cellular matrix (ECM) such as collagen and elastin, causing various chronic skin diseases and skin aging including skin cancer and pigmentation. Accordingly, in recent years, it is necessary to develop a multifunctional material having multifunctionality such as wrinkle improvement and skin aging improvement while protecting the skin from ultraviolet rays or active oxygen, which are the main causes of skin aging.

Meanwhile, plants have long been a source of various natural substances that help human welfare. Most of these substances are secondary metabolites, and they are used for pharmaceuticals, food additives, cosmetic raw materials, fragrances, colorants, and the like. Despite the synthesis of numerous new compounds by the development of the field of organic synthesis, plants are still recognized as a source of new substances. Considering that thousands of new substances with new chemical structures are discovered in plants every year, and many of them have physiological activity, plants can be said to be important raw materials.

With respect to cosmetics containing plant-derived ingredients for preventing aging or wrinkles of the skin, Korean Patent Application Laid-Open No. 2015-0143375 discloses a skin wrinkle-improving cosmetic composition containing an extract of red succulent root, Korean Patent Laid-Open Patent Publication No. In Publication No. 2015-0009266, various compositions have been developed, such as disclosing a cosmetic composition for wrinkle improvement containing elderberry and Euari extract as active ingredients. research is needed.

Korean Patent Publication No. 2015-0143375 Korean Patent Publication No. 2015-0009266

In order to solve the above problems, the present invention has no skin toxicity, can improve wrinkles by promoting collagen synthesis in the skin, and inhibits photoaging caused by ultraviolet rays to prevent skin aging and wrinkle improvement and Provided are a body lotion composition prepared by using ginseng oil and frankincense oil to prevent skin aging, and a method for preparing the same.

The object is a primary oil mixing step of preparing a primary mixed oil by mixing 30 to 70% by weight of ginseng oil and 30 to 70% by weight of frankincense oil; a fractionation step of fractionating the first mixed oil with hexane to obtain a mixed oil fraction; A secondary oil mixing step of preparing a secondary mixed oil by mixing 2-5 parts by weight of forsythia extract and 2-5 parts by weight of eggplant extract with the fraction with respect to 100 parts by weight of the fraction; and a lotion preparation step of preparing a lotion by mixing the secondary mixed oil with shea butter, an emulsifier, an emulsion stabilizer, a viscosity enhancer and purified water; It can be achieved by a body lotion composition prepared using ginseng oil and frankincense oil for anti-wrinkle improvement and skin aging, including, and a method for preparing the same.

Specifically, the purified water of the lotion manufacturing step is 40% by weight of filtered water obtained by repeatedly filtering tertiary distilled water 2 to 3 times through a filtrate in which activated carbon, cypress chips and tourmaline powder are mixed in a 2: 1: 2 weight ratio and hydrogen in distilled water. It may be prepared by mixing 60% by weight of hydrogen water prepared by injecting.

Specifically, the first oil mixing step may further include adding 10-20 parts by weight of acai berry oil and 10-20 parts by weight of amaranth seed oil with respect to 100 parts by weight of ginseng and frankincense mixed oil. .

Specifically, the ginseng oil is a mixture of ginseng seeds and ginseng flowers in a weight ratio of 1: 1, immersed in a water bath in which activated carbon, ginkgo leaves and distilled water are mixed in a weight ratio of 2: 1: 7 for 2 hours, and steamed 2-3 times And it may be obtained by pressing after drying.

Specifically, the lotion of the lotion manufacturing step is 1-3% by weight of secondary mixed oil, 5-10% by weight of shea butter, 10-15% by weight of emulsifier, 5-10% by weight of emulsion stabilizer, 0.1-2% by weight of viscosity enhancer and 60 to 75% by weight of purified water.

The body lotion composition prepared using ginseng oil and frankincense oil according to the present invention is non-toxic to the skin by using natural ginseng oil and frankincense oil, and can improve wrinkles by promoting collagen synthesis in the skin, and UV rays It can be used as a body lotion composition for wrinkle improvement and skin aging prevention because it can prevent skin aging by inhibiting photoaging caused by skin aging.

1 is a flowchart illustrating a method for preparing a body lotion composition prepared using ginseng oil and frankincense oil for wrinkle improvement and skin aging prevention according to an embodiment.

Hereinafter, embodiments will be described in detail with reference to the accompanying drawings. However, since various changes may be made to the embodiments, the scope of the patent application is not limited or limited by these embodiments. It should be understood that all modifications, equivalents and substitutes for the embodiments are included in the scope of the rights.

Specific structural or functional descriptions of the embodiments are disclosed for purposes of illustration only, and may be changed and implemented in various forms. Accordingly, the embodiments are not limited to a specific disclosure form, and the scope of the present specification includes changes, equivalents, or substitutes included in the technical spirit.

Although terms such as first or second may be used to describe various elements, these terms should be interpreted only for the purpose of distinguishing one element from another. For example, a first component may be termed a second component, and similarly, a second component may also be termed a first component.

When a component is referred to as being “connected” to another component, it may be directly connected or connected to the other component, but it should be understood that another component may exist in between.

Terms used in the examples are used for the purpose of description only, and should not be construed as limiting. The singular expression includes the plural expression unless the context clearly dictates otherwise. In the present specification, terms such as “comprise” or “have” are intended to designate that a feature, number, step, operation, component, part, or combination thereof described in the specification exists, but one or more other features It is to be understood that this does not preclude the possibility of the presence or addition of numbers, steps, operations, components, parts, or combinations thereof.

Unless defined otherwise, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which the embodiment belongs. Terms such as those defined in a commonly used dictionary should be interpreted as having a meaning consistent with the meaning in the context of the related art, and should not be interpreted in an ideal or excessively formal meaning unless explicitly defined in the present application. does not

Advantages and features of the present invention and methods of achieving them will become apparent with reference to the embodiments described below in detail in conjunction with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, but will be implemented in a variety of different forms, only these embodiments allow the disclosure of the present invention to be complete, and common knowledge in the technical field to which the present invention belongs It is provided to fully inform the possessor of the scope of the invention, and the present invention is only defined by the scope of the claims.

In the embodiments of the present invention, unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by those of ordinary skill in the art to which the present invention belongs. have meaning Terms such as those defined in a commonly used dictionary should be interpreted as having a meaning consistent with the meaning in the context of the related art, and unless explicitly defined in an embodiment of the present invention, an ideal or excessively formal meaning is not interpreted as

The shapes, sizes, proportions, angles, numbers, etc. disclosed in the drawings for explaining the embodiments of the present invention are illustrative and the present invention is not limited to the illustrated matters. In addition, in describing the present invention, if it is determined that a detailed description of a related known technology may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted. When 'including', 'having', 'consisting', etc. mentioned in this specification are used, other parts may be added unless 'only' is used. When a component is expressed in the singular, the case in which the plural is included is included unless specifically stated otherwise.

In interpreting the components, it is interpreted as including an error range even if there is no separate explicit description.

The size and thickness of each component shown in the drawings are illustrated for convenience of description, and the present invention is not necessarily limited to the size and thickness of the illustrated component.

Each feature of the various embodiments of the present invention may be partially or wholly combined or combined with each other, and as those skilled in the art will fully understand, technically various interlocking and driving are possible, and each embodiment may be independently implemented with respect to each other. It may be possible to implement together in a related relationship.

One aspect of the present application, a primary oil mixing step of preparing a primary mixed oil by mixing 30 to 70% by weight of ginseng oil and 30 to 70% by weight of frankincense oil; a fractionation step of fractionating the first mixed oil with hexane to obtain a mixed oil fraction; A secondary oil mixing step of preparing a secondary mixed oil by mixing 2-5 parts by weight of forsythia extract and 2-5 parts by weight of eggplant extract with the fraction with respect to 100 parts by weight of the fraction; and a lotion preparation step of preparing a lotion by mixing the secondary mixed oil with shea butter, an emulsifier, an emulsion stabilizer, a viscosity enhancer and purified water; It provides a method for preparing a body lotion composition prepared using ginseng oil and frankincense oil for wrinkle improvement and skin aging, comprising:

The wrinkle refers to fine lines caused by the deterioration of the skin, and may be caused by a genetic cause, a decrease in collagen present in the dermis of the skin, an external environment, and the like.

In the present invention, wrinkle improvement may be achieved by promoting collagen synthesis.

The skin aging is the appearance of symptoms such as a decrease in elasticity of the skin, a decrease in gloss, generation of wrinkles, weakening of regeneration, or severe dryness, and may be caused by the passage of time or an external environment. In the present invention, skin aging prevention may be to suppress photoaging caused by UV stimulation.

The photoaging refers to a phenomenon in which skin damage occurs, such as when the skin's elasticity and moisture are reduced and wrinkles are formed upon repeated or long-term exposure to ultraviolet rays of sunlight.

Hereinafter, a method of manufacturing a body lotion composition prepared using ginseng oil and frankincense oil for wrinkle improvement and skin aging prevention according to an embodiment of the present invention can be described with reference to FIG. 1 .

First, 30 to 70% by weight of ginseng oil and 30 to 70% by weight of frankincense oil are mixed to prepare a primary mixed oil.

The ginseng refers to ginseng of the Araliaceae family (Panax ginseng C. A. Meyer), and the root is mainly used as a medicine. Ginseng is used for body weakness, malaise, fatigue, loss of appetite, vomiting and diarrhea, and helps the lungs function, produces sap, and enhances eye and renal function. In addition, pharmacological effects such as cortical excitability and inhibition, balance, anti-fatigue, anti-aging, immune enhancement, heart contraction, gonadotrophin, hyperglycemia suppression, protein synthesis promotion, homeostasis maintenance, anticancer, detoxification, etc. have been reported.

In one embodiment, the ginseng oil is a mixture of ginseng seeds and ginseng flowers in a 1: 1 weight ratio mixed with activated carbon, ginkgo leaves and distilled water 2: 1: 7 by weight immersion in a water tank mixed for 2 hours, 2-3 It may be obtained by pressing after steaming and drying the ash.

The frankincense means that the sap that flows out when a wound on the trunk of a frankincense tree called frankincense tree (B. carterii) in Korea is hardened, and this means frankincense (乳香), Frankincence in English Also called olibanum, it is mainly used as a flavoring agent. Frankincense is effective in relieving pain and eliminating boils, and while it has effects such as strong antiseptic action, inhibition of bacterial growth and arthritis, it is characterized by non-toxicity.

In one embodiment, the first mixing oil manufacturing step further comprises adding 10-20 parts by weight of acai berry oil and 10-20 parts by weight of amaranth seed oil with respect to 100 parts by weight of ginseng and frankincense mixed oil may be doing

Next, the primary mixed oil is fractionated with hexane to obtain a mixed oil fraction.

The hexane is also called n-hexane or positive hexane, belongs to an aliphatic hydrocarbon, and is present in cracked oil and crude oil of petroleum hydrocarbons. At room temperature and pressure, it is a colorless, transparent, boiling point of 69℃, flammable liquid, which dissolves some organic substances in addition to animal and plant oils and fats and mineral oil. It is almost insoluble in water. If inhaled in large quantities, it is anesthetic. It is used as an extraction solvent for various oils and fats.

The fractionation refers to a method performed to separate a specific component or a specific group of components from a mixture containing various components, and a product obtained through such fractionation is referred to as a fraction.

The fractionation method for obtaining the fraction is not particularly limited, and may be performed according to a method commonly used in the art.

Next, 2 to 5 parts by weight of forsythia extract and 2 to 5 parts by weight of eggplant extract are mixed with the fraction with respect to 100 parts by weight of the fraction.

The forsythia is a deciduous shrub of the dicotyledonous plant, Gentian, oleaceae, and its roots, stems, leaves, and fruits are used medicinally. In particular, the fruit of forsythia is called Yeongyo and is prescribed in oriental medicine for cold, fever, purulent disease, lymphadenitis, urinary incontinence, boil, nephritis, eczema, etc. It is known that it contains various medicinal ingredients.

The eggplant refers to an annual grass of the solanaceae family of the dicotyledonous plant order, and specifically refers to the fruit of the plant. Eggplants contain polyphenols, which have antioxidant effects, and are rich in anthocyanins, helping eye health.

Finally, a lotion is prepared by mixing the secondary mixed oil with shea butter, an emulsifier, an emulsion stabilizer, a viscosity enhancer and purified water.

The shea butter refers to vegetable fat extracted from the seeds of the shea tree, and 85 to 90% of stearic acid, a saturated fatty acid and oleic acid, an unsaturated fatty acid, dissolves at a temperature similar to body temperature, but is called butter because it is solid at room temperature. It is useful for dry skin by supplying moisture and nutrition to the skin, and is often used in ointments and cosmetics. As it contains linoleic acid, arachidonic acid, and vitamins A and E, it helps to relieve small wounds and inflammation.

The emulsifier is a type of surfactant and refers to a compound capable of lowering the surface tension at the interface. An interface is an interface between a gas and a liquid, a liquid and a liquid, and a liquid and a solid. Surfactants play a role in relieving tension in these interfaces. For this reason, the surface tension of the interface is weakened. Emulsifiers serve to lower the interfacial tension, especially when mixing liquids (oils) and liquids (water) with each other. The mixture obtained at this time is called an emulsion. When the types of emulsions are classified by type, they can be broadly divided into oil in water (O/W type), water in oil (W/O type), and multiple type emulsions.

The emulsion stabilizer means a component that helps to form an emulsion and stabilizes the formed emulsion, and prevents or reduces the coalescence of the emulsions by mechanisms such as electrical repulsion, viscosity change, and film formation on the emulsion film.

The viscosity enhancer means a component that enhances the viscosity of the liquid. It is mainly used in cosmetics such as lotions or creams.

In one embodiment, the lotion of the lotion manufacturing step is a secondary mixed oil 1-3% by weight, shea butter 5-10% by weight, emulsifier 10-15% by weight, emulsion stabilizer 5-10% by weight, viscosity enhancer 0.1 ~ It may be composed of 2% by weight and 60 to 75% by weight of purified water.

In one embodiment, the purified water in the lotion manufacturing step is 40% by weight of filtered water obtained by repeatedly filtering tertiary distilled water 2 to 3 times through a filtrate in which activated carbon, cypress chips and tourmaline powder are mixed in a 2: 1: 2 weight ratio, and It may be prepared by mixing 60% by weight of hydrogen water prepared by injecting hydrogen into distilled water.

The cypress chip means a pulverized cypress tree, an evergreen arboreous tree of the Coniferaceae family, of an angiosperm family, into a small chip size. Cypress trees contain a lot of natural antibacterial substances called phytoncides, which have excellent sterilization effect.

The tourmaline powder refers to powdered tourmaline, a crystalline mineral of a hexagonal system, also called tourmaline, and the chemical composition is a crystalline borosilicate mineral in which elements such as aluminum, iron, magnesium, sodium, lithium or potassium are mixed.

Hereinafter, the configuration of the present invention and its effects will be described in more detail through specific examples and comparative examples. However, these examples are for explaining the present invention in more detail, and the scope of the present invention is not limited to these examples.

[Example 1]

First, ginseng seeds and ginseng flowers were mixed in a weight ratio of 1: 1 and then immersed in a water bath in which activated carbon, ginkgo leaves and distilled water were mixed in a weight ratio of 2: 1: 7 for 2 hours. After the immersion mixture was steamed and dried, the process was repeated 3 times and then compressed with a press to obtain ginseng oil.

60% by weight of the ginseng oil and 40% by weight of frankincense oil were mixed to prepare a first mixed oil, and then the mixed oil was fractionated with hexane to obtain a fraction.

Based on 100 parts by weight of the obtained fraction, 3 parts by weight of forsythia extract and 5 parts by weight of eggplant extract were mixed with the fraction to prepare a secondary mixed oil.

Next, 40% by weight of filtered water obtained by repeatedly filtering tertiary distilled water three times through a filtrate in which activated carbon, cypress wood chips and tourmaline powder are mixed in a weight ratio of 2: 1: 2, and hydrogen water prepared by injecting hydrogen into distilled water by 60 weight % was mixed to prepare purified water.

Finally, 3% by weight of the secondary mixed oil, 5% by weight of shea butter, 10% by weight of an emulsifier, 7% by weight of an emulsion stabilizer, 0.5% by weight of a viscosity enhancer, and 74.5% by weight of purified water are mixed to improve wrinkles and prevent skin aging. A body lotion composition prepared using ginseng oil and frankincense oil was prepared. The prepared body lotion composition was named Example 1.

[Example 2]

Prepared in the same manner as in Example 1, but by adding 10 parts by weight of acai berry oil and 10 parts by weight of amaranth seed oil to 100 parts by weight of ginseng and frankincense mixed oil in the first oil mixing step. One body lotion composition was named Example 2.

[Experimental Example 1: Comparison of collagen synthesis level in skin cells]

Collagen is synthesized from a precursor called procollagen. The procollagen has a propeptide sequence at the N- and C-terminals, and plays an important role in the folding and polymerization of procollagen. Therefore, it is known that activation of PIP (procollagen type I C-peptide) promotes collagen synthesis and affects cell proliferation and wrinkle improvement.

In order to confirm the collagen synthesis enhancing effect of Examples 1 and 2, after culturing human fibroblasts in three culture dishes, Examples 1 and 2 were added to each culture dish by 100 µL at a concentration of 100 µg/mL. time incubation. The third culture dish to which the composition was not added was tested as a control. Antibody-POD conjugate solution and cell supernatant were added thereto, and then incubated for 3 hours more. After adding the substrate, the level of PIP was measured by measuring the absorbance at 450 nm in a microplate reader. The PIP level measurement results are shown in Table 1 below.

control Example 1 Example 2 PIP level (ng/ml) 150 198 215

As shown in Table 1, it could be confirmed that Examples 1 and 2 both showed a high PIP level compared to the control group to promote collagen synthesis, and that Examples 1 and 2 had a wrinkle-improving effect.

[Experimental Example 2: Comparison of the protective effect of skin cells against UV stimulation]

In order to confirm the cell protection ability of the body lotion composition against ultraviolet rays, after irradiating the cultured human fibroblasts with UVB at an intensity of 7 mJ/cm ² , Examples 1 and 2 were each 100 μL at a concentration of 100 μg/mL. was added and cultured for 24 hours. Fibroblasts without the composition were set as a control group, and fibroblasts irradiated with UVB were set as a positive control group, and fibroblasts that were not irradiated with UVB were set as a negative control group, and the experiment was conducted. Thereafter, the cell viability was measured through the MTT assay, and the measurement results are shown in Table 2 below.

negative control positive control Example 1 Example 2 Cell viability (%) 100 52 68 70

As shown in Table 2, it was confirmed that the cell viability of the fibroblasts treated with Examples 1 and 2 was significantly increased compared to the control group, thereby confirming that the body lotion composition according to the present invention had a protective effect against UV stimulation. .

Claims (3)

After mixing 30-70% by weight of ginseng oil and 30-70% by weight of frankincense oil, 10-20 parts by weight of acai berry oil and 10-20 parts by weight of amaranth seed oil with respect to 100 parts by weight of ginseng and frankincense mixed oil a primary oil mixing step of preparing a primary mixed oil by further adding parts;
a fractionation step of fractionating the first mixed oil with hexane to obtain a mixed oil fraction;
A secondary oil mixing step of preparing a secondary mixed oil by mixing 2-5 parts by weight of forsythia extract and 2-5 parts by weight of eggplant extract with the fraction with respect to 100 parts by weight of the fraction; and
A lotion is prepared by mixing the secondary mixed oil with shea butter, an emulsifier, an emulsion stabilizer, a viscosity enhancer and purified water, wherein the purified water is a mixture of tertiary distilled water with activated carbon, cypress chips and tourmaline powder in a 2: 1: 2 weight ratio. A lotion manufacturing step that is prepared by mixing 40% by weight of filtered water repeatedly filtered 2-3 times in the filtered sieve and 60% by weight of hydrogen water prepared by injecting hydrogen into distilled water; A method of preparing a body lotion composition prepared using ginseng oil and frankincense oil for anti-wrinkle improvement and skin aging, comprising:
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