KR102433648B1 - 항인간 헤모글로빈 모노클로날 항체 또는 항체 키트, 항인간 헤모글로빈 모노클로날 항체 고정화 불용성 담체 입자, 및 이들을 이용한 측정 시약 또는 측정 방법 - Google Patents

항인간 헤모글로빈 모노클로날 항체 또는 항체 키트, 항인간 헤모글로빈 모노클로날 항체 고정화 불용성 담체 입자, 및 이들을 이용한 측정 시약 또는 측정 방법 Download PDF

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KR102433648B1
KR102433648B1 KR1020187037157A KR20187037157A KR102433648B1 KR 102433648 B1 KR102433648 B1 KR 102433648B1 KR 1020187037157 A KR1020187037157 A KR 1020187037157A KR 20187037157 A KR20187037157 A KR 20187037157A KR 102433648 B1 KR102433648 B1 KR 102433648B1
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monoclonal antibody
hemoglobin
nite
insoluble carrier
human hemoglobin
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KR20190015338A (ko
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료타 야스이
메구미 유이
미쓰루 마키노단
야스히로 세키
지사 사카니시
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에이껜 가가꾸 가부시끼가이샤
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G01N33/57535—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G01N33/546—Synthetic resin as water suspendable particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
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  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Food Science & Technology (AREA)
  • Pathology (AREA)
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  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020187037157A 2016-05-30 2017-05-26 항인간 헤모글로빈 모노클로날 항체 또는 항체 키트, 항인간 헤모글로빈 모노클로날 항체 고정화 불용성 담체 입자, 및 이들을 이용한 측정 시약 또는 측정 방법 Active KR102433648B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2016-107343 2016-05-30
JP2016107343 2016-05-30
PCT/JP2017/019736 WO2017209001A1 (ja) 2016-05-30 2017-05-26 抗ヒトヘモグロビンモノクローナル抗体若しくは抗体キット、抗ヒトヘモグロビンモノクローナル抗体固定化不溶性担体粒子、及びこれらを用いた測定試薬若しくは測定方法

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KR20190015338A KR20190015338A (ko) 2019-02-13
KR102433648B1 true KR102433648B1 (ko) 2022-08-17

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US (1) US11175292B2 (enExample)
EP (1) EP3467498B1 (enExample)
JP (2) JP6991968B2 (enExample)
KR (1) KR102433648B1 (enExample)
CN (1) CN110383067B (enExample)
AU (1) AU2017275081B2 (enExample)
ES (1) ES2985318T3 (enExample)
SG (1) SG11201809558PA (enExample)
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WO (1) WO2017209001A1 (enExample)

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CN112752974A (zh) * 2018-09-26 2021-05-04 荣研化学株式会社 血红蛋白的测定试剂、测定试剂盒和测定方法
CN112979799B (zh) * 2019-12-18 2022-11-08 东莞市朋志生物科技有限公司 一种包含血红蛋白抗原结构域的结合蛋白
CN111057150B (zh) * 2019-12-30 2021-10-29 深圳开立生物医疗科技股份有限公司 一种乳胶微球及其应用以及糖化血红蛋白检测试剂盒
CN114478759A (zh) * 2020-11-12 2022-05-13 东莞市朋志生物科技有限公司 抗人血红蛋白的抗体及其应用和诊断试剂盒

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552295A (en) 1994-03-02 1996-09-03 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies to bovine haptoglobin and methods for detecting serum haptoglobin levels
US20080227208A1 (en) 2007-03-16 2008-09-18 Hsiao-Ching Yee Devices and Methods for Detection of Occult Blood

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61137064A (ja) 1984-12-07 1986-06-24 Fujirebio Inc 大腸癌の予備スクリ−ニング方法
JPH02193071A (ja) 1989-01-20 1990-07-30 Green Cross Corp:The ハプトグロビン―ヘモグロビン複合体測定用試薬キット及びそれを用いるハプトグロビン―ヘモグロビン複合体の測定法
JPH05322888A (ja) * 1992-05-18 1993-12-07 Toyobo Co Ltd 遊離ヘモグロビンの定量方法および遊離ヘモグロビン定量キット
US6342219B1 (en) * 1999-04-28 2002-01-29 Board Of Regents, The University Of Texas System Antibody compositions for selectively inhibiting VEGF
TWI235159B (en) 1999-06-30 2005-07-01 Dev Center Biotechnology Anti-human hemoglobin monoclonal antibodies for detecting fecal occult blood, producing hybridomas and uses thereof
JP2001221800A (ja) 2000-02-14 2001-08-17 Internatl Reagents Corp 複合体の測定方法
JP4390963B2 (ja) 2000-04-05 2009-12-24 シスメックス株式会社 免疫測定方法及び試薬キット
US7166476B2 (en) * 2000-08-29 2007-01-23 Kyowa Medex Co., Ltd. Highly reproducible agglutination immunoassay method and reagents
JP5227418B2 (ja) * 2007-11-20 2013-07-03 エフ．ホフマン−ラ ロシュ アーゲー マーカー組み合わせカルプロテクチンおよびヘモグロビン／ハプトグロビン複合体の使用による便試料からの結腸直腸癌の評価方法
CN101236210A (zh) * 2008-01-29 2008-08-06 王学生 快速联检血红蛋白-结合珠蛋白复合物和大便潜血试剂
JP5191291B2 (ja) 2008-07-04 2013-05-08 和光純薬工業株式会社 便検体中ヘモグロビンの測定方法及び測定試薬キット
WO2010013525A1 (ja) 2008-07-31 2010-02-04 日東紡績株式会社 複合体の測定方法およびそれに用いるキット
DE102012013888A1 (de) * 2012-07-09 2014-05-22 Schebo Biotech Ag Testkit (Kombi-Schnelltest) zum synchronen Nachweis von Biomarkern im Stuhl zur Erkennung pathologischer Veränderungen im Gastrointestinaltrakt, insbesondere im Darm
CN104515859A (zh) * 2014-12-17 2015-04-15 杭州慧缘泰医疗器械有限公司 血红蛋白、血红蛋白-结合珠蛋白复合物、转铁蛋白联检试剂盒及其制备方法、检测方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552295A (en) 1994-03-02 1996-09-03 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies to bovine haptoglobin and methods for detecting serum haptoglobin levels
US20080227208A1 (en) 2007-03-16 2008-09-18 Hsiao-Ching Yee Devices and Methods for Detection of Occult Blood

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Chalkias et al, Am J Clin Oncol (2011), vol 34, no 6, pp 561-566.
Ivo R Horin et al, European Journal of Haematology (2003), vol 71, no 4, pp 289-293.
Takashi Meguro et al, Hokkaido Journal of Medical Science (1994), vol 69, pp 995-1009.
Yasushi Hamaya et al, Journal of Gastroenterological Cancer Screening (2012), vol 50, no 3, pp 345-350.

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KR20190015338A (ko) 2019-02-13
AU2017275081A1 (en) 2019-01-03
JP6991968B2 (ja) 2022-01-13
EP3467498B1 (en) 2024-07-03
US11175292B2 (en) 2021-11-16
JPWO2017209001A1 (ja) 2019-03-28
CN110383067B (zh) 2023-07-21
AU2017275081A2 (en) 2019-01-17
CN110383067A (zh) 2019-10-25
EP3467498A4 (en) 2019-11-13
TW201802472A (zh) 2018-01-16
EP3467498A1 (en) 2019-04-10
TWI800483B (zh) 2023-05-01
ES2985318T3 (es) 2024-11-05
JP2022033935A (ja) 2022-03-02
AU2017275081B2 (en) 2023-12-07
US20200319183A1 (en) 2020-10-08
WO2017209001A1 (ja) 2017-12-07
SG11201809558PA (en) 2018-12-28
JP7386220B2 (ja) 2023-11-24

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