KR102421013B1 - 삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도 - Google Patents

삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도 Download PDF

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KR102421013B1
KR102421013B1 KR1020170060713A KR20170060713A KR102421013B1 KR 102421013 B1 KR102421013 B1 KR 102421013B1 KR 1020170060713 A KR1020170060713 A KR 1020170060713A KR 20170060713 A KR20170060713 A KR 20170060713A KR 102421013 B1 KR102421013 B1 KR 102421013B1
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trigeminal
formula
painful
trigeminal neuralgia
pharmaceutical composition
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KR20170131241A (ko
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조민재
황선관
이한주
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에스케이바이오팜 주식회사
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020170060713A 2016-05-19 2017-05-16 삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도 Active KR102421013B1 (ko)

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KR20160061386 2016-05-19
KR1020160061386 2016-05-19

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KR20170131241A KR20170131241A (ko) 2017-11-29
KR102421013B1 true KR102421013B1 (ko) 2022-07-14

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US (2) US11207295B2 (enExample)
EP (1) EP3459542B1 (enExample)
JP (1) JP6960415B2 (enExample)
KR (1) KR102421013B1 (enExample)
CN (1) CN109310669B (enExample)
AU (1) AU2017267160B2 (enExample)
CA (1) CA3024284C (enExample)
DK (1) DK3459542T3 (enExample)
ES (1) ES2887338T3 (enExample)
MX (1) MX389613B (enExample)
PL (1) PL3459542T3 (enExample)
PT (1) PT3459542T (enExample)
RU (1) RU2751504C2 (enExample)
WO (1) WO2017200317A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102635936B1 (ko) 2016-12-14 2024-02-13 에스케이바이오팜 주식회사 탈수초성 질환의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
JP7408643B2 (ja) * 2018-09-21 2024-01-05 エスケー バイオファーマスティカルズ カンパニー リミテッド カルバメート化合物及びそれを含む製剤の急性ストレス障害又は心的外傷後ストレス障害の予防、軽減又は治療のための使用
WO2020080866A1 (ko) * 2018-10-19 2020-04-23 에스케이바이오팜 주식회사 카바메이트 화합물의 당뇨병성 말초 신경병증 또는 화학요법 유발 말초 신경병증의 예방, 완화 또는 치료를 위한 용도

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100323410A1 (en) 2009-06-22 2010-12-23 Sang Chul Lim Method for preparation of carbamic acid (r)-1-aryl-2-tetrazolyl-ethyl ester
US20110111467A1 (en) 2009-10-15 2011-05-12 Sang Chul Lim Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester
KR101286499B1 (ko) * 2005-04-22 2013-07-16 에스케이바이오팜 주식회사 신경치료용 아졸 화합물

Family Cites Families (7)

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US3415840A (en) * 1965-10-22 1968-12-10 American Home Prod Pyrazole-1-ethanol derivatives
DE2628420A1 (de) * 1976-06-24 1978-01-05 Bayer Ag 1-acyloxy-2-imidazolyl-1-phenyl- aethane, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide und nematizide
SK57899A3 (en) * 1996-12-31 2000-05-16 Guilford Pharm Inc N-linked ureas and carbamates of heterocyclic thioesters
RU2283106C2 (ru) * 2001-02-27 2006-09-10 Орто-Макнейл Фармасьютикал, Инк. Производные карбаматов для использования для лечения боли
JP4227121B2 (ja) * 2005-06-08 2009-02-18 独立行政法人科学技術振興機構 神経因性疼痛治療剤
CA2817290A1 (en) * 2010-11-11 2012-05-18 Josef Penninger Compounds and methods for treating pain
MA39448B1 (fr) * 2014-05-09 2019-12-31 Tecnimede Sociedade Tecnico Medicinal S (r)-pirlindole et ses sels pharmaceutiquement acceptables destinés à un usage médical

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101286499B1 (ko) * 2005-04-22 2013-07-16 에스케이바이오팜 주식회사 신경치료용 아졸 화합물
US20100323410A1 (en) 2009-06-22 2010-12-23 Sang Chul Lim Method for preparation of carbamic acid (r)-1-aryl-2-tetrazolyl-ethyl ester
US20110111467A1 (en) 2009-10-15 2011-05-12 Sang Chul Lim Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Epilepsy Research, 92(2-3):89-124 (2010.12.01.)
European Journal of Medicinal Chemistry, 36(5):421-433 (2001)
NEUROLOGIC ASPECTS OF SYSTEMIC DISEASE PART I: "Chapter 33: Fibromyalgia", HANDBOOK OF CLINICAL NEUROLOGY, 119:513-527 (2014)
Novel Neurotherapeutic for Epilepsy, Neuropathic Pain and Bipolar Disorder, YKP3089 - SK biopharmaceuticals, <https://www.epilepsy.com/sites/core/files/atoms/files/6-6_S_James_Lee.pdf>(2012.12.31.)

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CA3024284A1 (en) 2017-11-23
US11207295B2 (en) 2021-12-28
AU2017267160B2 (en) 2022-11-10
RU2018144784A (ru) 2020-06-19
JP2019516722A (ja) 2019-06-20
US20220087976A1 (en) 2022-03-24
DK3459542T3 (da) 2021-09-13
RU2751504C2 (ru) 2021-07-14
CN109310669B (zh) 2022-02-22
WO2017200317A1 (ko) 2017-11-23
BR112018073556A2 (pt) 2019-03-19
CN109310669A (zh) 2019-02-05
AU2017267160A1 (en) 2018-12-13
EP3459542A1 (en) 2019-03-27
JP6960415B2 (ja) 2021-11-05
US20190175555A1 (en) 2019-06-13
RU2018144784A3 (enExample) 2020-08-11
MX2018014081A (es) 2019-09-02
PT3459542T (pt) 2021-08-24
EP3459542B1 (en) 2021-06-30
ES2887338T3 (es) 2021-12-22
CA3024284C (en) 2024-01-23
PL3459542T3 (pl) 2021-12-27
MX389613B (es) 2025-03-20
EP3459542A4 (en) 2020-01-08
KR20170131241A (ko) 2017-11-29

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