KR102382489B1 - 페니실린 ｇ 아실라제 - Google Patents

페니실린 ｇ 아실라제 Download PDF

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KR102382489B1
KR102382489B1 KR1020187035333A KR20187035333A KR102382489B1 KR 102382489 B1 KR102382489 B1 KR 102382489B1 KR 1020187035333 A KR1020187035333 A KR 1020187035333A KR 20187035333 A KR20187035333 A KR 20187035333A KR 102382489 B1 KR102382489 B1 KR 102382489B1
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KR20180137025A (ko
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조바나 나조르
베스나 미첼
데이비드 엘가르트
카트리나 더블유 렉사
니키 델라스
로버트 케빈 오르
오스카 알비조
라비 데이비드 가르시아
주디 빅토리아 안토니오 비드야
코트니 다이안 모펫
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코덱시스, 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01011—Penicillin amidase (3.5.1.11), i.e. penicillin-amidohydrolase

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020187035333A 2016-05-05 2017-05-05 페니실린 ｇ 아실라제 Active KR102382489B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662332103P 2016-05-05 2016-05-05
US62/332,103 2016-05-05
PCT/US2017/031342 WO2017193022A1 (en) 2016-05-05 2017-05-05 Penicillin-g acylases

Publications (2)

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KR20180137025A KR20180137025A (ko) 2018-12-26
KR102382489B1 true KR102382489B1 (ko) 2022-04-01

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KR1020187035333A Active KR102382489B1 (ko) 2016-05-05 2017-05-05 페니실린 ｇ 아실라제

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US (4) US10724025B2 (cg-RX-API-DMAC7.html)
EP (1) EP3452587B1 (cg-RX-API-DMAC7.html)
JP (1) JP7128519B2 (cg-RX-API-DMAC7.html)
KR (1) KR102382489B1 (cg-RX-API-DMAC7.html)
CN (1) CN109715793A (cg-RX-API-DMAC7.html)
AU (1) AU2017260355B2 (cg-RX-API-DMAC7.html)
CA (1) CA3021009A1 (cg-RX-API-DMAC7.html)
DK (1) DK3452587T3 (cg-RX-API-DMAC7.html)
IL (1) IL262550B (cg-RX-API-DMAC7.html)
MX (1) MX389364B (cg-RX-API-DMAC7.html)
SG (1) SG11201808957UA (cg-RX-API-DMAC7.html)
WO (1) WO2017193022A1 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102382489B1 (ko) 2016-05-05 2022-04-01 코덱시스, 인코포레이티드 페니실린 ｇ 아실라제
EP3645713A4 (en) 2017-06-27 2021-06-30 Codexis, Inc. PENICILLIN-G ACYLASES
CN114760980B (zh) * 2019-09-12 2024-10-18 科德克希思公司 针对10-乙酰基-3,7-二羟基吩噁嗪的过氧化物酶活性

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US20120270282A1 (en) * 2008-11-10 2012-10-25 Codexis, Inc. Penicillin-g acylases

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EP3452587B1 (en) 2021-09-08
EP3452587A4 (en) 2020-03-18
IL262550B (en) 2022-05-01
JP7128519B2 (ja) 2022-08-31
EP3452587A1 (en) 2019-03-13
SG11201808957UA (en) 2018-11-29
DK3452587T3 (da) 2021-10-11
US20170321202A1 (en) 2017-11-09
MX389364B (es) 2025-03-19
KR20180137025A (ko) 2018-12-26
AU2017260355A1 (en) 2018-11-01
MX2018013259A (es) 2019-04-22
NZ747064A (en) 2025-05-02
WO2017193022A1 (en) 2017-11-09
US11965192B2 (en) 2024-04-23
IL262550A (en) 2018-12-31
AU2017260355B2 (en) 2023-03-30
US11214786B2 (en) 2022-01-04
JP2019514395A (ja) 2019-06-06
US20220154164A1 (en) 2022-05-19
US20250034543A1 (en) 2025-01-30
CN109715793A (zh) 2019-05-03
US20200339972A1 (en) 2020-10-29
US10724025B2 (en) 2020-07-28
CA3021009A1 (en) 2017-11-09

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