AU2017260355B2 - Penicillin-G acylases - Google Patents

Penicillin-G acylases Download PDF

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Publication number
AU2017260355B2
AU2017260355B2 AU2017260355A AU2017260355A AU2017260355B2 AU 2017260355 B2 AU2017260355 B2 AU 2017260355B2 AU 2017260355 A AU2017260355 A AU 2017260355A AU 2017260355 A AU2017260355 A AU 2017260355A AU 2017260355 B2 AU2017260355 B2 AU 2017260355B2
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AU
Australia
Prior art keywords
insulin
acylase
seq
penicillin
protected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2017260355A
Other languages
English (en)
Other versions
AU2017260355A1 (en
Inventor
Oscar Alvizo
Nikki DELLAS
David ELGART
Ravi David Garcia
Katrina W. Lexa
Vesna Mitchell
Courtney Dianne Moffett
Jovana Nazor
Robert Kevin Orr
Judy Victoria Antonio Viduya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Codexis Inc
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of AU2017260355A1 publication Critical patent/AU2017260355A1/en
Application granted granted Critical
Publication of AU2017260355B2 publication Critical patent/AU2017260355B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01011—Penicillin amidase (3.5.1.11), i.e. penicillin-amidohydrolase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2017260355A 2016-05-05 2017-05-05 Penicillin-G acylases Active AU2017260355B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662332103P 2016-05-05 2016-05-05
US62/332,103 2016-05-05
PCT/US2017/031342 WO2017193022A1 (en) 2016-05-05 2017-05-05 Penicillin-g acylases

Publications (2)

Publication Number Publication Date
AU2017260355A1 AU2017260355A1 (en) 2018-11-01
AU2017260355B2 true AU2017260355B2 (en) 2023-03-30

Family

ID=60203339

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017260355A Active AU2017260355B2 (en) 2016-05-05 2017-05-05 Penicillin-G acylases

Country Status (12)

Country Link
US (4) US10724025B2 (cg-RX-API-DMAC7.html)
EP (1) EP3452587B1 (cg-RX-API-DMAC7.html)
JP (1) JP7128519B2 (cg-RX-API-DMAC7.html)
KR (1) KR102382489B1 (cg-RX-API-DMAC7.html)
CN (1) CN109715793A (cg-RX-API-DMAC7.html)
AU (1) AU2017260355B2 (cg-RX-API-DMAC7.html)
CA (1) CA3021009A1 (cg-RX-API-DMAC7.html)
DK (1) DK3452587T3 (cg-RX-API-DMAC7.html)
IL (1) IL262550B (cg-RX-API-DMAC7.html)
MX (1) MX389364B (cg-RX-API-DMAC7.html)
SG (1) SG11201808957UA (cg-RX-API-DMAC7.html)
WO (1) WO2017193022A1 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102382489B1 (ko) 2016-05-05 2022-04-01 코덱시스, 인코포레이티드 페니실린 ｇ 아실라제
EP3645713A4 (en) 2017-06-27 2021-06-30 Codexis, Inc. PENICILLIN-G ACYLASES
CN114760980B (zh) * 2019-09-12 2024-10-18 科德克希思公司 针对10-乙酰基-3,7-二羟基吩噁嗪的过氧化物酶活性

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Publication number Priority date Publication date Assignee Title
US20120270282A1 (en) * 2008-11-10 2012-10-25 Codexis, Inc. Penicillin-g acylases

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Also Published As

Publication number Publication date
EP3452587B1 (en) 2021-09-08
EP3452587A4 (en) 2020-03-18
IL262550B (en) 2022-05-01
JP7128519B2 (ja) 2022-08-31
EP3452587A1 (en) 2019-03-13
SG11201808957UA (en) 2018-11-29
DK3452587T3 (da) 2021-10-11
US20170321202A1 (en) 2017-11-09
MX389364B (es) 2025-03-19
KR20180137025A (ko) 2018-12-26
AU2017260355A1 (en) 2018-11-01
MX2018013259A (es) 2019-04-22
NZ747064A (en) 2025-05-02
WO2017193022A1 (en) 2017-11-09
US11965192B2 (en) 2024-04-23
IL262550A (en) 2018-12-31
US11214786B2 (en) 2022-01-04
KR102382489B1 (ko) 2022-04-01
JP2019514395A (ja) 2019-06-06
US20220154164A1 (en) 2022-05-19
US20250034543A1 (en) 2025-01-30
CN109715793A (zh) 2019-05-03
US20200339972A1 (en) 2020-10-29
US10724025B2 (en) 2020-07-28
CA3021009A1 (en) 2017-11-09

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