KR102367941B1 - 락토스 불내증의 증상을 감소시키거나 예방하는 베타-카세인 a2 - Google Patents

락토스 불내증의 증상을 감소시키거나 예방하는 베타-카세인 a2 Download PDF

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KR102367941B1
KR102367941B1 KR1020167003267A KR20167003267A KR102367941B1 KR 102367941 B1 KR102367941 B1 KR 102367941B1 KR 1020167003267 A KR1020167003267 A KR 1020167003267A KR 20167003267 A KR20167003267 A KR 20167003267A KR 102367941 B1 KR102367941 B1 KR 102367941B1
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casein
beta
milk
lactose
composition
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KR20160030974A (ko
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앤드류 존 클라크
말라브 수친 트리베디
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디 에이2 밀크 컴퍼니 리미티드
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20Milk; Whey; Colostrum
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/19Dairy proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Dairy Products (AREA)
  • Confectionery (AREA)
  • Peptides Or Proteins (AREA)
KR1020167003267A 2013-07-12 2014-07-10 락토스 불내증의 증상을 감소시키거나 예방하는 베타-카세인 a2 Active KR102367941B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020207019514A KR102291660B1 (ko) 2013-07-12 2014-07-10 락토스 불내증의 증상을 감소시키거나 예방하는 베타-카세인 a2

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361845480P 2013-07-12 2013-07-12
US61/845,480 2013-07-12
PCT/NZ2014/000141 WO2015005804A1 (en) 2013-07-12 2014-07-10 Beta-casein a2 and reducing or preventing symptoms of lactose intolerance

Related Child Applications (1)

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KR1020207019514A Division KR102291660B1 (ko) 2013-07-12 2014-07-10 락토스 불내증의 증상을 감소시키거나 예방하는 베타-카세인 a2

Publications (2)

Publication Number Publication Date
KR20160030974A KR20160030974A (ko) 2016-03-21
KR102367941B1 true KR102367941B1 (ko) 2022-02-24

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KR1020167003267A Active KR102367941B1 (ko) 2013-07-12 2014-07-10 락토스 불내증의 증상을 감소시키거나 예방하는 베타-카세인 a2
KR1020207019514A Active KR102291660B1 (ko) 2013-07-12 2014-07-10 락토스 불내증의 증상을 감소시키거나 예방하는 베타-카세인 a2

Family Applications After (1)

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KR1020207019514A Active KR102291660B1 (ko) 2013-07-12 2014-07-10 락토스 불내증의 증상을 감소시키거나 예방하는 베타-카세인 a2

Country Status (20)

Country Link
US (3) US20160136238A1 (https=)
EP (2) EP3542805A1 (https=)
JP (2) JP6436592B2 (https=)
KR (2) KR102367941B1 (https=)
CN (3) CN110800803A (https=)
AU (2) AU2014287862B2 (https=)
BR (1) BR112016000612B8 (https=)
CA (2) CA3214545A1 (https=)
CL (1) CL2016000064A1 (https=)
DK (1) DK3019180T3 (https=)
ES (1) ES2743194T3 (https=)
IL (2) IL243366B (https=)
MX (2) MX368912B (https=)
MY (2) MY190309A (https=)
NZ (2) NZ754642A (https=)
PH (2) PH12016500032B1 (https=)
RU (1) RU2671562C2 (https=)
SG (2) SG10201710237PA (https=)
WO (1) WO2015005804A1 (https=)
ZA (1) ZA201600007B (https=)

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Publication number Priority date Publication date Assignee Title
EP3542813A1 (en) * 2013-05-31 2019-09-25 The A2 Milk Company Limited Beta-casein a2 and prevention of inflammation of the bowel
JP7137745B2 (ja) * 2015-05-22 2022-09-15 ズィ・エイツー・ミルク・カンパニー・リミテッド ベータカゼインa2および抗酸化能
WO2017003300A1 (en) * 2015-06-29 2017-01-05 The A2 Milk Company Limited A2 beta-casein and viscosity of milk products
WO2017171563A1 (en) 2016-03-30 2017-10-05 The A2 Milk Company Limited Beta-caseins and cognitive function
JP6873234B2 (ja) * 2016-09-30 2021-05-19 ズィ・エイツー・ミルク・カンパニー・リミテッド ベータカゼイン類および腸微生物叢
NL2019906B1 (en) * 2017-11-14 2019-05-20 Ausnutria Hyproca B V Composition comprising a2 b-casein and a vegetable fat mixture
WO2021003741A1 (zh) * 2019-07-11 2021-01-14 北京三元食品股份有限公司 β-酪蛋白A2、其组合物在促进双歧杆菌属增殖中的应用
CN112205476A (zh) * 2019-07-11 2021-01-12 北京三元食品股份有限公司 β-酪蛋白A2、其组合物在促进双歧杆菌属增殖中的应用
EP4377480A4 (en) * 2021-07-30 2025-09-24 Active Genomes Expressed Diagnostics Corp METHODS AND COMPOSITIONS FOR THE TREATMENT OF LIVER CANCER AND LIVER DISEASE
AU2024262008A1 (en) * 2023-04-25 2025-11-13 The A2 Milk Company Limited Beta-caseins in infant milk formula and use for reducing crying episodes in infants
WO2024225919A1 (en) * 2023-04-25 2024-10-31 The A2 Milk Company Limited Beta-caseins in infant milk formula and use for reducing regurgitation episodes in infants
CN117322467A (zh) * 2023-10-11 2024-01-02 东北农业大学 A2β-酪蛋白在制备功能性食品中的应用
CN117322466A (zh) * 2023-11-02 2024-01-02 光明乳业股份有限公司 一种新型婴幼儿食用的发酵乳及其制备方法

Citations (2)

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WO2001000047A1 (en) 1999-06-29 2001-01-04 The New Zealand Milk Institute Limited Prophylactic dietary supplement based on milk
WO2004030690A1 (en) 2002-10-04 2004-04-15 A2 Corporation Limited THERAPEUTIC USES OF β-CASEIN A2 AND DIETARY SUPPLEMENT CONTAINING β-CASEIN A2

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CA2204245C (en) 1994-11-04 2008-07-22 Robert Bartlett Elliott Method of selecting non-diabetogenic milk or milk products and milk or milk products so selected
US7094949B2 (en) * 1995-05-16 2006-08-22 A2 Corporation Limited Breeding and milking cows for milk free of β-casein A1
WO1996036239A1 (en) 1995-05-16 1996-11-21 Corran Norman Stuart Mclachlan Food product and process
US7029702B2 (en) * 1998-07-07 2006-04-18 Ritter Natural Sciences Llc Method for increasing lactose tolerance in mammals exhibiting lactose intolerance
AU9037401A (en) 2000-09-08 2002-03-22 New Zealand Dairy Board Milk containing beta-casein with proline at position 67 does not aggravate neurological disorders
DK1663298T3 (da) * 2003-09-23 2019-10-14 Dsm Ip Assets Bv Anvendelse af prolinspecifikke endoproteaser til hydrolyse af peptider og proteiner
US7618669B2 (en) * 2005-06-01 2009-11-17 Mead Johnson Nutrition Company Low-lactose partially hydrolyzed infant formula
CN1899054A (zh) * 2006-07-17 2007-01-24 颜贻谦 去糖牛奶的制作方法
JP2012522505A (ja) * 2009-04-03 2012-09-27 ネステク ソシエテ アノニム ミルク様飲料
AU2010238184B2 (en) * 2009-04-15 2014-09-04 Glanbia Nutritionals (Ireland) Limited A reduced lactose milk product and a process for the preparation thereof
DE102010009582A1 (de) * 2010-02-05 2011-08-11 Vitacare GmbH & Co. KG, 60318 Mittel zur Anwendung bei Lactasemangel und Lactoseintoleranz
MX389785B (es) * 2011-07-26 2025-03-18 Nucitec Sa De Cv Composicion nutrimental para niños que presentan reflujo, colico y/o estreñimiento.
CN103315063A (zh) * 2012-03-19 2013-09-25 基斯有限公司 可预防疾病的婴儿配方奶粉
EP3542813A1 (en) * 2013-05-31 2019-09-25 The A2 Milk Company Limited Beta-casein a2 and prevention of inflammation of the bowel
US20170086481A1 (en) * 2014-06-03 2017-03-30 Abbott Laboratories Nutritional compositions comprising a lipophilic active ingredient

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2001000047A1 (en) 1999-06-29 2001-01-04 The New Zealand Milk Institute Limited Prophylactic dietary supplement based on milk
WO2004030690A1 (en) 2002-10-04 2004-04-15 A2 Corporation Limited THERAPEUTIC USES OF β-CASEIN A2 AND DIETARY SUPPLEMENT CONTAINING β-CASEIN A2

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CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, Vol. 46, No. 1, pp. 93-100 (2006)
MUTATION RESEARCH, Vol. 690, No. 1-2, pp. 64-70 (2010)

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Publication number Publication date
US20220175882A1 (en) 2022-06-09
KR102291660B1 (ko) 2021-08-19
CA2917492C (en) 2023-11-14
IL261143B (en) 2021-02-28
PH12016500032B1 (en) 2019-10-25
IL261143A (en) 2018-10-31
AU2014287862B2 (en) 2019-07-11
SG10201710237PA (en) 2018-01-30
HK1223846A1 (en) 2017-08-11
KR20200085375A (ko) 2020-07-14
RU2018131604A3 (https=) 2022-04-19
JP6436592B2 (ja) 2018-12-12
MY172939A (en) 2019-12-16
RU2015156804A3 (https=) 2018-05-31
ZA201600007B (en) 2017-11-29
AU2019203684B2 (en) 2021-08-05
ES2743194T3 (es) 2020-02-18
IL243366B (en) 2018-11-29
BR112016000612B8 (pt) 2022-02-22
SG11201510707YA (en) 2016-01-28
NZ715985A (en) 2022-09-30
AU2019203684A1 (en) 2019-06-20
AU2014287862A1 (en) 2016-02-11
CN114832092A (zh) 2022-08-02
EP3542805A1 (en) 2019-09-25
PH12019550112A1 (en) 2020-09-14
CN105431156A (zh) 2016-03-23
NZ754642A (en) 2022-09-30
PH12016500032A1 (en) 2016-03-28
MX2019012446A (es) 2020-02-03
EP3019180B1 (en) 2019-05-29
RU2671562C2 (ru) 2018-11-02
WO2015005804A1 (en) 2015-01-15
BR112016000612A2 (https=) 2017-07-25
MX368912B (es) 2019-10-21
MY190309A (en) 2022-04-13
MX2016000308A (es) 2016-11-14
BR112016000612B1 (pt) 2021-11-03
EP3019180A4 (en) 2017-03-08
CL2016000064A1 (es) 2016-12-16
DK3019180T3 (da) 2019-08-26
RU2018131604A (ru) 2018-11-20
JP2016523958A (ja) 2016-08-12
CA2917492A1 (en) 2015-01-15
JP6990154B2 (ja) 2022-01-12
RU2015156804A (ru) 2017-08-17
CN110800803A (zh) 2020-02-18
KR20160030974A (ko) 2016-03-21
US20160136238A1 (en) 2016-05-19
CA3214545A1 (en) 2015-01-15
MX394585B (es) 2025-03-04
US20200147173A1 (en) 2020-05-14
JP2018203753A (ja) 2018-12-27
EP3019180A1 (en) 2016-05-18

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