KR102348484B1 - 인플루엔자의 진단을 위한 방법 및 키트 - Google Patents

인플루엔자의 진단을 위한 방법 및 키트 Download PDF

Info

Publication number
KR102348484B1
KR102348484B1 KR1020157031383A KR20157031383A KR102348484B1 KR 102348484 B1 KR102348484 B1 KR 102348484B1 KR 1020157031383 A KR1020157031383 A KR 1020157031383A KR 20157031383 A KR20157031383 A KR 20157031383A KR 102348484 B1 KR102348484 B1 KR 102348484B1
Authority
KR
South Korea
Prior art keywords
neuraminidase
immunoassay
assay
sample
influenza
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020157031383A
Other languages
English (en)
Korean (ko)
Other versions
KR20160018479A (ko
Inventor
로버트 캠벨
케빈 지. 돌란
에릭 펠로우스
랜달 에이. 호크
로스 제이콥슨
브루스 피트너 제이.
글렌 봉크
라자쉐이커 카체
우파마 굴라티
허먼 히멜
로즈메리 비. 에반스-스톰스
Original Assignee
벡톤 디킨슨 앤드 컴퍼니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 벡톤 디킨슨 앤드 컴퍼니 filed Critical 벡톤 디킨슨 앤드 컴퍼니
Publication of KR20160018479A publication Critical patent/KR20160018479A/ko
Application granted granted Critical
Publication of KR102348484B1 publication Critical patent/KR102348484B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/11—Orthomyxoviridae, e.g. influenza virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020157031383A 2013-04-01 2014-04-01 인플루엔자의 진단을 위한 방법 및 키트 Expired - Fee Related KR102348484B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361807185P 2013-04-01 2013-04-01
US61/807,185 2013-04-01
PCT/US2014/032567 WO2014165536A1 (en) 2013-04-01 2014-04-01 Methods and kits for the diagnosis of influenza

Publications (2)

Publication Number Publication Date
KR20160018479A KR20160018479A (ko) 2016-02-17
KR102348484B1 true KR102348484B1 (ko) 2022-01-07

Family

ID=50625220

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157031383A Expired - Fee Related KR102348484B1 (ko) 2013-04-01 2014-04-01 인플루엔자의 진단을 위한 방법 및 키트

Country Status (11)

Country Link
US (3) US10317404B2 (https=)
EP (1) EP2981618B1 (https=)
JP (2) JP6591398B2 (https=)
KR (1) KR102348484B1 (https=)
CN (2) CN108663518B (https=)
AU (2) AU2014248225B2 (https=)
BR (1) BR112015025042B1 (https=)
CA (1) CA2908028C (https=)
ES (1) ES2754402T3 (https=)
RU (1) RU2713112C2 (https=)
WO (1) WO2014165536A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6411740B2 (ja) * 2013-01-15 2018-10-24 国立大学法人広島大学 ノイラミニダーゼ活性阻害剤の有効性を判定するための組成物、キットおよびその利用
KR102348484B1 (ko) 2013-04-01 2022-01-07 벡톤 디킨슨 앤드 컴퍼니 인플루엔자의 진단을 위한 방법 및 키트
US10520498B2 (en) 2017-03-14 2019-12-31 Becton, Dickinson And Company Devices and techniques for oral fluid collection and seroprotection testing
BR112019027993A2 (pt) * 2017-07-04 2020-07-07 Cavidi Ab métodos para avaliar a susceptibilidade de um vírus ao tratamento com um fármaco inibidor de uma enzima do vírus do tipo selvagem, para avaliar se um paciente tratado para uma infecção viral tem necessidade de alterar a terapia farmacológica com um fármaco inibidor da enzima viral e para determinar a carga de um vírus em uma amostra do paciente e a dita resistência do vírus ao tratamento com um fármaco inibidor de uma enzima do vírus do tipo selvagem, e, sistema
ES3037747T3 (en) 2017-09-21 2025-10-06 Becton Dickinson Co Augmented reality devices for hazardous contaminant testing
CN209559735U (zh) 2017-09-21 2019-10-29 贝克顿·迪金森公司 用于引导收集有害污染物样本的系统
CN209400423U (zh) * 2017-09-21 2019-09-17 贝克顿·迪金森公司 横向流测定物、测定物读取器装置和包括其的系统
EP3684944B1 (en) 2017-09-21 2025-01-01 Becton, Dickinson and Company Hazardous contaminant collection kit and rapid testing
CN111278987B (zh) * 2017-09-21 2024-02-23 贝克顿·迪金森公司 以高拾取和脱落效率收集有害污染物的采样系统和技术
CN111107939B (zh) 2017-09-21 2022-04-12 贝克顿·迪金森公司 引导有害污染物样品的收集的系统和模板及使用其的方法
AU2018337027B2 (en) 2017-09-21 2024-06-06 Becton, Dickinson And Company Hazardous contaminant collection kit and rapid testing
EP3760621A4 (en) * 2018-03-02 2021-08-25 Nihon Nohyaku Co., Ltd. AMIDE COMPOUND, OR SALT THEREOF, AND MICROBICIDE FOR AGRICULTURE AND HORTICULTURE, INCLUDING THIS COMPOUND AND METHOD OF USING THEREOF
KR102129937B1 (ko) * 2018-07-31 2020-07-03 재단법인 아산사회복지재단 종이기반 핵산검출용 키트 및 pcr 증폭산물을 분석하기 위한 방법
CN119264211A (zh) 2018-08-27 2025-01-07 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
CN113383222A (zh) 2019-01-28 2021-09-10 贝克顿·迪金森公司 具有集成的拭子和测试装置的有害污染物收集装置
WO2020196295A1 (ja) * 2019-03-25 2020-10-01 積水メディカル株式会社 呼吸器感染ウイルスの免疫学的分析方法及び検出キット
CA3183061A1 (en) * 2020-06-15 2021-12-23 Neuome Peptides Pte. Ltd. Lateral flow assay device for detection of analytes and method of detection thereof
JP2022018768A (ja) * 2020-07-16 2022-01-27 デンカ株式会社 簡易鼻腔粘膜表面付着粘液の採取方法および該検体中の被検出物を検出するための検査キット
KR20220060269A (ko) 2020-11-04 2022-05-11 인텔로스 주식회사 코로나 바이러스 감염증 및 인플루엔자 바이러스 감염증 동시 진단키트
KR102265441B1 (ko) * 2020-12-23 2021-06-15 충남대학교 산학협력단 화학 발광 기반의 조류 인플루엔자 바이러스 검출용 조성물 및 이의 용도
CN115015541A (zh) 2021-03-05 2022-09-06 全球诊断系统受益有限责任公司 带流体贮存器的诊断装置及相关方法和试剂盒
JP2023016529A (ja) * 2021-07-21 2023-02-02 東洋紡株式会社 イムノクロマト試験片
JP2023016530A (ja) * 2021-07-21 2023-02-02 東洋紡株式会社 イムノクロマト試験片
US20250066867A1 (en) * 2023-08-23 2025-02-27 Vedabio, Inc. Rapid detection of known and emerging influenza viruses

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000501748A (ja) * 1996-09-25 2000-02-15 オクラホマ メディカル リサーチ ファンデーション ４，７―ジアルコキシ―ｎ―アセチルノイラミン酸誘導体、および臨床的サンプル中のインフルエンザａ型およびｂ型ウィルスの検出法
JP3134999B2 (ja) 1989-12-29 2001-02-13 サイメックス コーポレイション ヒトのインフルエンザを診断する方法ならびにそれに使われる４位修飾の発色性ｎ―アセチルノイラミン酸基質
WO2007053487A2 (en) 2005-10-28 2007-05-10 Binax, Inc. Methods and devices for detection of the strain of a pathogen
US20080286758A1 (en) 2007-05-15 2008-11-20 Xing-Xiang Li Reagents and kits for detection of influenza virus and the like
JP2010525298A (ja) 2007-01-26 2010-07-22 アルボー ビータ コーポレーション インフルエンザウイルスの検出方法
WO2010139047A1 (en) 2009-06-01 2010-12-09 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health Reagents and methods for detecting influenza virus proteins

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590169A (en) 1983-11-18 1986-05-20 Beckman Instruments, Inc. Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations
US4810631A (en) 1986-05-12 1989-03-07 Becton, Dickinson And Company Signal enhancement in immunoassay by modulation of chemical catalysis
US4835099A (en) 1986-11-20 1989-05-30 Becton, Dickinson And Company Signal enhancement in immunoassay by modulation of enzymatic catalysis
US5017473A (en) 1987-05-26 1991-05-21 Becton, Dickinson And Company Homogeneous chemiluminescence immunoassay using a light absorbing material
US4904583A (en) 1987-05-26 1990-02-27 Becton, Dickinson And Company Cascade immunoassay by multiple binding reactions
CA2000678A1 (en) * 1988-11-17 1990-05-17 John E. Reardon Chromogenic substrate for esterase and immunoassay using same
US5314801A (en) 1992-11-06 1994-05-24 Becton, Dickinson And Company Probes to Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium paratuberculosis
US5470723A (en) 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
US5457027A (en) 1993-05-05 1995-10-10 Becton, Dickinson And Company Internal controls for isothermal nucleic acid amplification reactions
US5518884A (en) 1994-02-28 1996-05-21 Becton, Dickinson And Company Nucleic acid sequences specific for mycbacterium kansasii
US5639428A (en) 1994-07-19 1997-06-17 Becton Dickinson And Company Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
US5998221A (en) 1996-09-25 1999-12-07 Becton, Dickinson And Company Non-instrumented assay with quantitative and qualitative results
US6194220B1 (en) 1996-09-25 2001-02-27 Becton, Dickinson And Company Non-instrumented assay with quantitative and qualitative results
AU732916C (en) 1996-11-14 2002-06-06 Biota Scientific Management Pty Ltd Method and novel compounds for use therein
CA2314431A1 (en) * 1997-12-18 1999-06-24 Sepracor Inc. Screening assays for the detection and diagnosis of influenza virus
US6394952B1 (en) 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
US6267722B1 (en) 1998-02-03 2001-07-31 Adeza Biomedical Corporation Point of care diagnostic systems
US6303764B1 (en) 1998-09-24 2001-10-16 Zymetx, Inc. Synthesis of 4,7-dialkyl chromogenic glycosides of N-acetylneuraminic acids
EP1185710A2 (en) 1999-04-16 2002-03-13 Zymetx, Inc. Viral detection method using viral encoded enzymes and chemiluminescent substrates
US6420552B1 (en) 1999-09-10 2002-07-16 Zymetx, Inc. Syntheses of 4-alkyl chromogenic glycosides and 7-alkyl chromogenic glycosides of N-acetylneuraminic acids
EP1253203A1 (en) 2001-04-25 2002-10-30 Becton Dickinson and Company Rapid resuscitation, growth, capture and detection of microorganisms
EP1618214A4 (en) 2003-04-25 2008-02-13 Becton Dickinson Co DETECTION OF TYPES 1 AND 2 OF HERPES SIMPLEX VIRUS BY AMPLIFICATION OF NUCLEIC ACID
US8163237B2 (en) 2006-05-08 2012-04-24 Becton, Dickinson And Company Vascular access device pathogenic status indication
US8007999B2 (en) * 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
CA2652404A1 (en) * 2006-05-18 2007-11-29 Veterinarmedizinische Universitat Wien Detection method for influenza viruses
JP2008014751A (ja) 2006-07-05 2008-01-24 Denka Seiken Co Ltd 着色ラテックス粒子を用いるメンブレンアッセイ法およびキット
JP5300200B2 (ja) * 2006-08-31 2013-09-25 大阪府 トリインフルエンザウイルスに特異的な迅速診断法
US9086408B2 (en) * 2007-04-30 2015-07-21 Nexus Dx, Inc. Multianalyte assay
US8163474B2 (en) * 2008-03-15 2012-04-24 Arbor Vita Corporation NS1-NP diagnostics of influenza virus infection
KR102348484B1 (ko) 2013-04-01 2022-01-07 벡톤 디킨슨 앤드 컴퍼니 인플루엔자의 진단을 위한 방법 및 키트

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3134999B2 (ja) 1989-12-29 2001-02-13 サイメックス コーポレイション ヒトのインフルエンザを診断する方法ならびにそれに使われる４位修飾の発色性ｎ―アセチルノイラミン酸基質
JP2000501748A (ja) * 1996-09-25 2000-02-15 オクラホマ メディカル リサーチ ファンデーション ４，７―ジアルコキシ―ｎ―アセチルノイラミン酸誘導体、および臨床的サンプル中のインフルエンザａ型およびｂ型ウィルスの検出法
WO2007053487A2 (en) 2005-10-28 2007-05-10 Binax, Inc. Methods and devices for detection of the strain of a pathogen
JP2010525298A (ja) 2007-01-26 2010-07-22 アルボー ビータ コーポレーション インフルエンザウイルスの検出方法
US20080286758A1 (en) 2007-05-15 2008-11-20 Xing-Xiang Li Reagents and kits for detection of influenza virus and the like
WO2010139047A1 (en) 2009-06-01 2010-12-09 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health Reagents and methods for detecting influenza virus proteins

Also Published As

Publication number Publication date
AU2014248225A1 (en) 2015-10-29
JP2019215377A (ja) 2019-12-19
CN105264086B (zh) 2018-06-15
EP2981618B1 (en) 2019-08-28
AU2014248225B2 (en) 2020-06-25
JP6591398B2 (ja) 2019-10-16
RU2713112C2 (ru) 2020-02-03
JP7096219B2 (ja) 2022-07-05
RU2015141509A (ru) 2017-05-16
US10317404B2 (en) 2019-06-11
RU2015141509A3 (https=) 2018-03-30
KR20160018479A (ko) 2016-02-17
WO2014165536A8 (en) 2016-09-01
CN105264086A (zh) 2016-01-20
CN108663518A (zh) 2018-10-16
AU2020227005B2 (en) 2022-12-08
US12372525B2 (en) 2025-07-29
ES2754402T3 (es) 2020-04-17
BR112015025042B1 (pt) 2023-11-14
BR112015025042A2 (https=) 2017-09-05
US20190339272A1 (en) 2019-11-07
US11209433B2 (en) 2021-12-28
JP2016524127A (ja) 2016-08-12
CN108663518B (zh) 2022-03-11
CA2908028A1 (en) 2014-10-09
EP2981618A1 (en) 2016-02-10
US20160041167A1 (en) 2016-02-11
US20220146514A1 (en) 2022-05-12
WO2014165536A1 (en) 2014-10-09
AU2020227005A1 (en) 2020-09-17
CA2908028C (en) 2022-10-18

Similar Documents

Publication Publication Date Title
US12372525B2 (en) Methods and kits for the diagnosis of influenza
Nath et al. Diagnosis of herpes simplex virus: laboratory and point-of-care techniques
US10191052B2 (en) Methods of diagnosing and treating active tuberculosis in an individual
HK1215970A1 (zh) 定量的側向流測定法
US20190194717A1 (en) Method and kit for detecting pathogenic microorganism
Tabata et al. Antibody-free digital influenza virus counting based on neuraminidase activity
Verma et al. Rapid diagnostic methods for SARS-CoV-2 (COVID-19) detection: an evidence-based report
Kato et al. An easy, rapid, and sensitive method for detection of drug-resistant influenza virus by using a sialidase fluorescent imaging probe, BTP3-Neu5Ac
US10422806B1 (en) Methods for improving assays of biological samples
Guan et al. A microfluidic platform for the ultrasensitive detection of human enterovirus 71
WO2021209565A2 (en) In-vitro method and device for detecting a target nucleic acid and/or other macromolecules (such as peptides, proteins, carbohydrates or lipids)
Ngo et al. Humoral immune response in COVID-19 patients and novel design of lateral flow assay strip for simultaneous rapid detection of IgA/IgM/IgG antibodies against the SARS-CoV-2 virus
Hasan et al. A novel real-time PCR assay panel for detection of common respiratory pathogens in a convenient, strip-tube array format
CA3186975A1 (en) Methods, compositions, and systems for detecting coronavirus neutralizing antibodies
Huber et al. High efficacy of saliva in detecting SARS-CoV-2 by RTPCR in adults and children. Microorganisms 2021; 9: 642
Pandey et al. Diagnostic Tools for Rapid Screening and Detection of SARS-CoV-2 Infection. Vaccines 2022, 10, 1200
Afzal et al. Diagnostic accuracy of PANBIO COVID-19 rapid antigen method for screening in emergency cases
Aldunate et al. B-202 Clinical and analytical performance evaluation of Savanna RVP4 panel versus three methodologies
Mosadegh et al. Evaluating the efficiency of ELISA, monoplex and multiplex probe‐based real‐time reverse‐transcription PCR assays in the detection of SARS‐CoV‐2 (COVID‐19) and influenza A and B viruses: A cross‐sectional study
Sauer-Budge New Technologies for the Rapid Identification of Drug-Resistant Bacteria
Tohari et al. Development of Semi-In-house ELISAs that Enable a Reliable Individual and Simultaneous Detection of SARS-CoV-2 S and NP Antigens

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

R15-X000 Change to inventor requested

St.27 status event code: A-3-3-R10-R15-oth-X000

R16-X000 Change to inventor recorded

St.27 status event code: A-3-3-R10-R16-oth-X000

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

D13-X000 Search requested

St.27 status event code: A-1-2-D10-D13-srh-X000

D14-X000 Search report completed

St.27 status event code: A-1-2-D10-D14-srh-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E90F Notification of reason for final refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20250105

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

H13 Ip right lapsed

Free format text: ST27 STATUS EVENT CODE: N-4-6-H10-H13-OTH-PC1903 (AS PROVIDED BY THE NATIONAL OFFICE); TERMINATION CATEGORY : DEFAULT_OF_REGISTRATION_FEE

Effective date: 20250105

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20250105