KR102340393B1 - 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법 - Google Patents

편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법 Download PDF

Info

Publication number
KR102340393B1
KR102340393B1 KR1020207005263A KR20207005263A KR102340393B1 KR 102340393 B1 KR102340393 B1 KR 102340393B1 KR 1020207005263 A KR1020207005263 A KR 1020207005263A KR 20207005263 A KR20207005263 A KR 20207005263A KR 102340393 B1 KR102340393 B1 KR 102340393B1
Authority
KR
South Korea
Prior art keywords
microns
zolmitriptan
patch
microprotrusions
coating
Prior art date
Application number
KR1020207005263A
Other languages
English (en)
Korean (ko)
Other versions
KR20200032170A (ko
Inventor
마흐무드 아메리
도널드 켈러만
이 아오
Original Assignee
조사노 파마 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 조사노 파마 코포레이션 filed Critical 조사노 파마 코포레이션
Priority to KR1020217040858A priority Critical patent/KR20210155817A/ko
Publication of KR20200032170A publication Critical patent/KR20200032170A/ko
Application granted granted Critical
Publication of KR102340393B1 publication Critical patent/KR102340393B1/ko

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
KR1020207005263A 2017-08-23 2017-08-23 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법 KR102340393B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020217040858A KR20210155817A (ko) 2017-08-23 2017-08-23 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2017/048258 WO2019040063A1 (fr) 2017-08-23 2017-08-23 Procédé d'obtention rapide de concentrations thérapeutiques de zolmitriptan pour le traitement de migraines et de céphalées de horton

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020217040858A Division KR20210155817A (ko) 2017-08-23 2017-08-23 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법

Publications (2)

Publication Number Publication Date
KR20200032170A KR20200032170A (ko) 2020-03-25
KR102340393B1 true KR102340393B1 (ko) 2021-12-17

Family

ID=59829462

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020217040858A KR20210155817A (ko) 2017-08-23 2017-08-23 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법
KR1020207005263A KR102340393B1 (ko) 2017-08-23 2017-08-23 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020217040858A KR20210155817A (ko) 2017-08-23 2017-08-23 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법

Country Status (8)

Country Link
EP (1) EP3672570A1 (fr)
JP (2) JP7219384B2 (fr)
KR (2) KR20210155817A (fr)
CN (1) CN111050749A (fr)
AU (1) AU2017428907B2 (fr)
CA (2) CA3223555A1 (fr)
IL (1) IL272776B2 (fr)
WO (1) WO2019040063A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3416618A1 (fr) 2016-02-19 2018-12-26 ZP Opco, Inc. Procédé pour obtenir rapidement des concentrations thérapeutiques de triptans pour le traitement de migraines
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
WO2020245667A1 (fr) * 2019-06-06 2020-12-10 Kindeva Drug Delivery L.P. Support de microréseau destiné à un applicateur de microréseau
US11638809B2 (en) * 2019-06-28 2023-05-02 Passport Technologies, Inc. Triptan microporation delivery system
CN114699510A (zh) * 2021-12-29 2022-07-05 浙江湃肽生物有限公司 一种司美格鲁肽微针阵列及其制备方法
CN115887903A (zh) * 2022-12-15 2023-04-04 太平洋康泰科学仪器(济南)有限公司 微针贴片给药组件及给药方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013177376A (ja) * 2012-02-09 2013-09-09 Hisamitsu Pharmaceut Co Inc マイクロニードル用ゾルミトリプタン含有コーティング組成物及びマイクロニードルデバイス

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5080646A (en) 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5147296A (en) 1988-10-03 1992-09-15 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5169382A (en) 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
CA2253549C (fr) 1996-06-18 2005-10-25 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
US5741554A (en) 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
US5738728A (en) 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5743960A (en) 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
US5916524A (en) 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
DE69831268T2 (de) 1997-12-11 2006-03-09 Alza Corp., Palo Alto Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
AU739616B2 (en) 1997-12-11 2001-10-18 Alza Corporation Device for enhancing transdermal agent flux
DK1037687T3 (da) 1997-12-11 2009-01-26 Alza Corp Anordning til at forbedre et middels transdermale strömning
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
DE60024312T2 (de) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür
BR0114634A (pt) 2000-10-13 2004-01-27 Alza Corp Aplicador por impacto de disposição de microlâmina
RU2278623C2 (ru) 2000-10-13 2006-06-27 Алза Корпорейшн Держатель микровыступающего элемента для силового аппликатора
BR0114629A (pt) 2000-10-13 2004-01-20 Alza Corp Aparelho e método para a perfuração da pele com microprojeções
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
BR0114909A (pt) 2000-10-26 2004-02-03 Alza Corp Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
CA2444883A1 (fr) 2001-04-20 2002-10-31 Alza Corporation Reseau de micro-projections avec revetement contenant un principe benefique
ATE539687T1 (de) 2003-10-31 2012-01-15 Alza Corp Selbstbetätigter applikator für eine mikroprojektionsanordnung
EP1744683B1 (fr) 2004-05-13 2016-03-16 Alza Corporation Appareil et procédé pour la délivrance transdermique d'agents à base d'hormone parathyroïde
CA2680690A1 (fr) 2006-03-15 2007-09-20 Alza Corporation Appareil et procede d'administration transdermique d'agents hormonaux parathyroidiens destines a traiter ou prevenir l'osteopenie
WO2008115586A1 (fr) * 2007-03-21 2008-09-25 Alza Corporation Appareil et procédé d'administration transdermique d'un agoniste de triptane
WO2015017561A1 (fr) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Applicateur extra-plat de tampon de micro-aiguilles
EP3416618A1 (fr) * 2016-02-19 2018-12-26 ZP Opco, Inc. Procédé pour obtenir rapidement des concentrations thérapeutiques de triptans pour le traitement de migraines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013177376A (ja) * 2012-02-09 2013-09-09 Hisamitsu Pharmaceut Co Inc マイクロニードル用ゾルミトリプタン含有コーティング組成物及びマイクロニードルデバイス

Also Published As

Publication number Publication date
CA3223555A1 (fr) 2019-02-28
KR20200032170A (ko) 2020-03-25
JP2023033378A (ja) 2023-03-10
JP2021500397A (ja) 2021-01-07
IL272776B1 (en) 2024-02-01
KR20210155817A (ko) 2021-12-23
CA3073442A1 (fr) 2019-02-28
EP3672570A1 (fr) 2020-07-01
AU2017428907A1 (en) 2020-03-05
JP7219384B2 (ja) 2023-02-08
CA3073442C (fr) 2024-02-06
CN111050749A (zh) 2020-04-21
IL272776A (en) 2020-04-30
AU2017428907B2 (en) 2021-12-16
WO2019040063A1 (fr) 2019-02-28
IL272776B2 (en) 2024-06-01

Similar Documents

Publication Publication Date Title
KR102340393B1 (ko) 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법
US11660264B2 (en) Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
US11839683B2 (en) Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
AU2001297823B2 (en) Transdermal drug delivery devices having coated microprotrusions
US20230210762A1 (en) Transdermal drug delivery devices having psilocybin, lysergic acid diethylamide or 3,4-methylenedioxymethamphetamine coated microprotrusions
EP3626234B1 (fr) Timbre percutané à micro-aiguilles contenant du donépézil
AU2001297823A1 (en) Transdermal drug delivery devices having coated microprotrusions
US7455654B2 (en) Method and apparatus for reducing the incidence of tobacco use
US11660265B2 (en) Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
WO2008115586A1 (fr) Appareil et procédé d'administration transdermique d'un agoniste de triptane
US20230255881A1 (en) Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant