IL272776A - Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headaches - Google Patents
Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headachesInfo
- Publication number
- IL272776A IL272776A IL272776A IL27277620A IL272776A IL 272776 A IL272776 A IL 272776A IL 272776 A IL272776 A IL 272776A IL 27277620 A IL27277620 A IL 27277620A IL 272776 A IL272776 A IL 272776A
- Authority
- IL
- Israel
- Prior art keywords
- zolmitriptan
- migraines
- treatment
- cluster headaches
- therapeutic concentrations
- Prior art date
Links
- 208000006561 Cluster Headache Diseases 0.000 title 1
- 208000019695 Migraine disease Diseases 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- UTAZCRNOSWWEFR-ZDUSSCGKSA-N zolmitriptan Chemical compound C=1[C]2C(CCN(C)C)=CN=C2C=CC=1C[C@H]1COC(=O)N1 UTAZCRNOSWWEFR-ZDUSSCGKSA-N 0.000 title 1
- 229960001360 zolmitriptan Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medical Informatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2017/048258 WO2019040063A1 (en) | 2017-08-23 | 2017-08-23 | Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headaches |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL272776A true IL272776A (en) | 2020-04-30 |
| IL272776B1 IL272776B1 (en) | 2024-02-01 |
| IL272776B2 IL272776B2 (en) | 2024-06-01 |
Family
ID=59829462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL272776A IL272776B2 (en) | 2017-08-23 | 2017-08-23 | Method of rapidly achieving therapeutic concentrations of zolmitriptan for treatment of migraines and cluster headaches |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP3672570A1 (en) |
| JP (2) | JP7219384B2 (en) |
| KR (2) | KR102340393B1 (en) |
| CN (1) | CN111050749A (en) |
| AU (1) | AU2017428907B2 (en) |
| CA (2) | CA3223555A1 (en) |
| IL (1) | IL272776B2 (en) |
| WO (1) | WO2019040063A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017143345A1 (en) | 2016-02-19 | 2017-08-24 | Zp Opco, Inc. | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines |
| US11660264B2 (en) | 2017-08-23 | 2023-05-30 | Emergex USA Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches |
| US11660265B2 (en) | 2018-06-28 | 2023-05-30 | Emergex USA Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches |
| US20220241571A1 (en) * | 2019-06-06 | 2022-08-04 | Kindeva Drug Delivery L.P. | Microarray carrier for microarray applicator |
| JP2022540049A (en) * | 2019-06-28 | 2022-09-14 | パスポート テクノロジーズ、インコーポレイテッド | Triptan microporation delivery system |
| CN114699510B (en) * | 2021-12-29 | 2024-07-16 | 浙江湃肽生物有限公司 | Semiglutide microneedle array and preparation method thereof |
| CN115887903B (en) * | 2022-12-15 | 2024-09-27 | 太平洋康泰科学仪器（济南）有限公司 | Microneedle patch administration assembly and administration method |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5080646A (en) | 1988-10-03 | 1992-01-14 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
| US5147296A (en) | 1988-10-03 | 1992-09-15 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
| US5169382A (en) | 1988-10-03 | 1992-12-08 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
| ZA975326B (en) | 1996-06-18 | 1998-01-14 | Alza Corp | Device and method for enhancing transdermal flux of agents being delivered or sampled. |
| US5738728A (en) | 1996-07-26 | 1998-04-14 | Bio Dot, Inc. | Precision metered aerosol dispensing apparatus |
| US5743960A (en) | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
| US5916524A (en) | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
| US5741554A (en) | 1996-07-26 | 1998-04-21 | Bio Dot, Inc. | Method of dispensing a liquid reagent |
| KR100572539B1 (en) | 1997-12-11 | 2006-04-24 | 알자 코포레이션 | Device for enhancing transdermal agent flux |
| CA2313698C (en) | 1997-12-11 | 2008-04-15 | Alza Corporation | Device for enhancing transdermal agent flux |
| ATE406935T1 (en) | 1997-12-11 | 2008-09-15 | Alza Corp | DEVICE FOR IMPROVING THE TRANSDERMAL FLOW OF MEDICATIONS |
| US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
| DE60024312T2 (en) | 1999-12-10 | 2006-08-17 | Alza Corp., Mountain View | Transdermal drug delivery of macromolecular agents and device therefor |
| AU9682801A (en) | 2000-10-13 | 2002-04-22 | Alza Corp | Apparatus and method for piercing skin with microprotrusions |
| US7419481B2 (en) | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
| HUP0303576A2 (en) | 2000-10-13 | 2004-01-28 | Alza Corp | Microprotrusion member retainer for impact applicator |
| IL155375A0 (en) | 2000-10-13 | 2003-11-23 | Alza Corp | Microblade array impact applicator |
| HUP0302924A2 (en) | 2000-10-26 | 2003-12-29 | Alza Corp | Transdermal drug delivery devices having coated microprotrusions |
| US6855372B2 (en) | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
| CN100349632C (en) | 2001-04-20 | 2007-11-21 | 阿尔扎公司 | Microprojection array having beneficial agent contg coating |
| JP4682144B2 (en) | 2003-10-31 | 2011-05-11 | アルザ・コーポレーシヨン | Self-actuating applicator for microprojection arrays |
| JP5007427B2 (en) | 2004-05-13 | 2012-08-22 | アルザ コーポレイション | Apparatus and method for transdermal delivery of parathyroid hormone agents |
| EP2001453A4 (en) | 2006-03-15 | 2012-09-12 | Alza Corp | Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia |
| WO2008115586A1 (en) * | 2007-03-21 | 2008-09-25 | Alza Corporation | Apparatus and method for transdermal delivery of a triptan agonist |
| JP6121734B2 (en) * | 2012-02-09 | 2017-04-26 | 久光製薬株式会社 | Zolmitriptan-containing coating composition for microneedles and microneedle device |
| EP3027263A1 (en) | 2013-07-30 | 2016-06-08 | ZP Opco, Inc. | Low-profile microneedle patch applicator |
| WO2017143345A1 (en) * | 2016-02-19 | 2017-08-24 | Zp Opco, Inc. | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines |
-
2017
- 2017-08-23 CN CN201780094159.6A patent/CN111050749A/en active Pending
- 2017-08-23 EP EP17764703.9A patent/EP3672570A1/en active Pending
- 2017-08-23 AU AU2017428907A patent/AU2017428907B2/en not_active Expired - Fee Related
- 2017-08-23 IL IL272776A patent/IL272776B2/en unknown
- 2017-08-23 KR KR1020207005263A patent/KR102340393B1/en active IP Right Grant
- 2017-08-23 JP JP2020532539A patent/JP7219384B2/en active Active
- 2017-08-23 CA CA3223555A patent/CA3223555A1/en active Pending
- 2017-08-23 CA CA3073442A patent/CA3073442C/en active Active
- 2017-08-23 WO PCT/US2017/048258 patent/WO2019040063A1/en unknown
- 2017-08-23 KR KR1020217040858A patent/KR20210155817A/en active IP Right Grant
-
2023
- 2023-01-05 JP JP2023000670A patent/JP2023033378A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019040063A1 (en) | 2019-02-28 |
| JP2023033378A (en) | 2023-03-10 |
| KR20200032170A (en) | 2020-03-25 |
| JP7219384B2 (en) | 2023-02-08 |
| KR20210155817A (en) | 2021-12-23 |
| IL272776B1 (en) | 2024-02-01 |
| CA3073442C (en) | 2024-02-06 |
| IL272776B2 (en) | 2024-06-01 |
| JP2021500397A (en) | 2021-01-07 |
| CN111050749A (en) | 2020-04-21 |
| EP3672570A1 (en) | 2020-07-01 |
| AU2017428907A1 (en) | 2020-03-05 |
| AU2017428907B2 (en) | 2021-12-16 |
| CA3073442A1 (en) | 2019-02-28 |
| KR102340393B1 (en) | 2021-12-17 |
| CA3223555A1 (en) | 2019-02-28 |
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