KR102302505B1 - 경피 전달 시스템 - Google Patents

경피 전달 시스템 Download PDF

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Publication number
KR102302505B1
KR102302505B1 KR1020157037128A KR20157037128A KR102302505B1 KR 102302505 B1 KR102302505 B1 KR 102302505B1 KR 1020157037128 A KR1020157037128 A KR 1020157037128A KR 20157037128 A KR20157037128 A KR 20157037128A KR 102302505 B1 KR102302505 B1 KR 102302505B1
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KR
South Korea
Prior art keywords
buprenorphine
hour
pressure sensitive
sensitive adhesive
treatment system
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KR1020157037128A
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English (en)
Korean (ko)
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KR20160014064A (ko
Inventor
토마스 힐레
가브리엘 보이어
프랑크 자이베르츠
슈-룬 바인하이머
Original Assignee
에르테에스 로만 테라피-시스테메 아게
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Application filed by 에르테에스 로만 테라피-시스테메 아게 filed Critical 에르테에스 로만 테라피-시스테메 아게
Publication of KR20160014064A publication Critical patent/KR20160014064A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0246Adhesive bandages or dressings characterised by the skin-adhering layer
    • A61F13/0256Adhesive bandages or dressings characterised by the skin-adhering layer characterized by the parametric properties of the adhesive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4748Quinolines; Isoquinolines forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020157037128A 2013-06-04 2014-06-04 경피 전달 시스템 Active KR102302505B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361830975P 2013-06-04 2013-06-04
US61/830,975 2013-06-04
PCT/EP2014/061567 WO2014195352A1 (en) 2013-06-04 2014-06-04 Transdermal delivery system

Publications (2)

Publication Number Publication Date
KR20160014064A KR20160014064A (ko) 2016-02-05
KR102302505B1 true KR102302505B1 (ko) 2021-09-15

Family

ID=51022809

Family Applications (1)

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KR1020157037128A Active KR102302505B1 (ko) 2013-06-04 2014-06-04 경피 전달 시스템

Country Status (34)

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US (6) US20160008294A1 (enExample)
EP (2) EP3106153A1 (enExample)
JP (1) JP6559121B2 (enExample)
KR (1) KR102302505B1 (enExample)
CN (1) CN105377245B (enExample)
AP (1) AP2015008920A0 (enExample)
AR (1) AR096521A1 (enExample)
AU (1) AU2014276910B2 (enExample)
BR (1) BR112015029920A2 (enExample)
CA (1) CA2914425C (enExample)
CL (1) CL2015003377A1 (enExample)
CR (1) CR20150647A (enExample)
CY (1) CY1118054T1 (enExample)
DE (1) DE112014002664T5 (enExample)
DK (1) DK2810646T3 (enExample)
EA (1) EA201592246A1 (enExample)
ES (1) ES2599802T3 (enExample)
GB (1) GB2529789A (enExample)
HK (1) HK1222135A1 (enExample)
HU (1) HUE031662T2 (enExample)
LT (1) LT2810646T (enExample)
MA (1) MA38698B1 (enExample)
MX (1) MX362614B (enExample)
NI (1) NI201500170A (enExample)
PE (1) PE20160002A1 (enExample)
PH (1) PH12015502550A1 (enExample)
PL (1) PL2810646T3 (enExample)
PT (1) PT2810646T (enExample)
SG (1) SG11201509218SA (enExample)
SI (1) SI2810646T1 (enExample)
TN (1) TN2015000493A1 (enExample)
TW (1) TW201509416A (enExample)
WO (1) WO2014195352A1 (enExample)
ZA (1) ZA201509309B (enExample)

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TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片
DE112014002664T5 (de) 2013-06-04 2016-04-07 Lts Lohmann Therapie-Systeme Ag Transdermales Verabreichungssystem
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EP4238580A3 (en) 2014-05-20 2023-10-25 LTS Lohmann Therapie-Systeme AG Transdermal delivery system including an interface mediator
EP3145502B1 (en) 2014-05-20 2022-07-06 LTS Lohmann Therapie-Systeme AG Transdermal delivery system containing rotigotine
EP3145503A1 (en) 2014-05-20 2017-03-29 LTS Lohmann Therapie-Systeme AG Method for adjusting the release of active agent in a transdermal delivery system
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CN113952319A (zh) * 2021-11-30 2022-01-21 烟台大学 一种含丁丙诺啡的骨架型透皮贴剂及其制备方法

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CY1118054T1 (el) 2017-06-28
AP2015008920A0 (en) 2015-12-31
CN105377245A (zh) 2016-03-02
MA38698A1 (fr) 2017-02-28
CA2914425A1 (en) 2014-12-11
PH12015502550A1 (en) 2016-02-22
US20200316055A1 (en) 2020-10-08
HK1204766A1 (en) 2015-12-04
TN2015000493A1 (en) 2017-04-06
CA2914425C (en) 2019-09-17
BR112015029920A2 (pt) 2017-07-25
PT2810646T (pt) 2016-10-05
AU2014276910A1 (en) 2016-01-28
DE112014002664T5 (de) 2016-04-07
HUE031662T2 (en) 2017-07-28
ZA201509309B (en) 2017-11-29
SG11201509218SA (en) 2015-12-30
US20170128384A1 (en) 2017-05-11
TW201509416A (zh) 2015-03-16
AU2014276910B2 (en) 2017-03-09
GB201522307D0 (en) 2016-02-03
EP3106153A1 (en) 2016-12-21
ES2599802T3 (es) 2017-02-03
KR20160014064A (ko) 2016-02-05
US20160008294A1 (en) 2016-01-14
PE20160002A1 (es) 2016-01-23
CN105377245B (zh) 2018-07-17
NI201500170A (es) 2016-08-05
GB2529789A (en) 2016-03-02
EA201592246A1 (ru) 2016-05-31
AR096521A1 (es) 2016-01-13
WO2014195352A1 (en) 2014-12-11
EP2810646A1 (en) 2014-12-10
SI2810646T1 (sl) 2016-11-30
MX362614B (es) 2019-01-28
US11529345B2 (en) 2022-12-20
US20160101100A1 (en) 2016-04-14
LT2810646T (lt) 2016-10-25
DK2810646T3 (en) 2016-10-31
US20200237748A1 (en) 2020-07-30
US20180092905A1 (en) 2018-04-05
CR20150647A (es) 2016-02-19
MX2015016123A (es) 2016-07-21
MA38698B1 (fr) 2017-10-31
EP2810646B1 (en) 2016-07-27
PL2810646T3 (pl) 2017-02-28
HK1222135A1 (zh) 2017-06-23
JP6559121B2 (ja) 2019-08-14
CL2015003377A1 (es) 2016-06-17
JP2016520638A (ja) 2016-07-14

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