KR102301867B1 - Nrf2 조절제 - Google Patents

Nrf2 조절제 Download PDF

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KR102301867B1
KR102301867B1 KR1020167018852A KR20167018852A KR102301867B1 KR 102301867 B1 KR102301867 B1 KR 102301867B1 KR 1020167018852 A KR1020167018852 A KR 1020167018852A KR 20167018852 A KR20167018852 A KR 20167018852A KR 102301867 B1 KR102301867 B1 KR 102301867B1
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methyl
benzo
mmol
dioxido
triazol
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KR20160098392A (ko
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제프리 찰스 보엠
토마스 글랜머 데이비스
앨리슨 조-앤 울포드
샬럿 메어리 그리피쓰-존스
헨드리카 마리아 제라다 윌렘스
데이빗 노턴
고든 삭스티
토마스 다니엘 하이트맨
틴디 리
제프리 케이. 컨스
로더릭 에스. 데이비스
홍싱 얀
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글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드
아스텍스 테라퓨틱스 리미티드
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    • C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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KR1020167018852A 2013-12-18 2014-12-17 Nrf2 조절제 Active KR102301867B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361917466P 2013-12-18 2013-12-18
US61/917,466 2013-12-18
US201461980091P 2014-04-16 2014-04-16
US61/980,091 2014-04-16
PCT/IB2014/067027 WO2015092713A1 (en) 2013-12-18 2014-12-17 Nrf2 regulators

Publications (2)

Publication Number Publication Date
KR20160098392A KR20160098392A (ko) 2016-08-18
KR102301867B1 true KR102301867B1 (ko) 2021-09-15

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US (2) US10144731B2 (https=)
EP (1) EP3083614B1 (https=)
JP (1) JP6630671B2 (https=)
KR (1) KR102301867B1 (https=)
CN (1) CN105829305B (https=)
AU (2) AU2014369153B2 (https=)
BR (1) BR112016014180A2 (https=)
CA (1) CA2934216C (https=)
CL (1) CL2016001516A1 (https=)
CR (1) CR20160272A (https=)
DO (1) DOP2016000145A (https=)
EA (1) EA030431B1 (https=)
ES (1) ES2784244T3 (https=)
IL (1) IL245727B (https=)
MX (1) MX370410B (https=)
PE (1) PE20160901A1 (https=)
PH (1) PH12016501151A1 (https=)
SG (1) SG11201604611SA (https=)
WO (1) WO2015092713A1 (https=)

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CA2988373A1 (en) * 2015-06-15 2016-12-22 Glaxosmithkline Intellectual Property Development Limited Nrf2 regulators
EP3766878B1 (en) * 2015-06-15 2022-03-16 GlaxoSmithKline Intellectual Property Development Limited Nrf2 regulators
SI3782996T1 (sl) * 2015-06-15 2024-06-28 Glaxosmithkline Intellectual Property Development Limited Nrf2 regulatorji
WO2017060855A1 (en) * 2015-10-06 2017-04-13 Glaxosmithkline Intellectual Property Development Limited Arylcyclohexyl pyrazoles as nrf2 regulators
US10364256B2 (en) 2015-10-06 2019-07-30 Glaxosmithkline Intellectual Property Development Limited Biaryl pyrazoles as NRF2 regulators
CN105566241B (zh) * 2016-01-18 2018-05-25 中国药科大学 1-磺酰胺基-4-芳氧基类化合物、制备方法及其医药用途
EP3411361B1 (en) 2016-02-03 2020-11-25 Rigel Pharmaceuticals, Inc. Nrf2 activating compounds and uses thereof
CN108779108A (zh) * 2016-12-06 2018-11-09 葛兰素史密斯克莱知识产权发展有限公司 3-(2,3-二氢-1h-茚-5-基)丙酸衍生物和它们作为nrf2调节剂的用途
WO2018109641A1 (en) * 2016-12-12 2018-06-21 Glaxosmithkline Intellectual Property Development Limited 3-carboxylic acid pyrroles as nrf2 regulators
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