KR102202183B1 - 치료제 전달 장치 - Google Patents

치료제 전달 장치 Download PDF

Info

Publication number
KR102202183B1
KR102202183B1 KR1020177010206A KR20177010206A KR102202183B1 KR 102202183 B1 KR102202183 B1 KR 102202183B1 KR 1020177010206 A KR1020177010206 A KR 1020177010206A KR 20177010206 A KR20177010206 A KR 20177010206A KR 102202183 B1 KR102202183 B1 KR 102202183B1
Authority
KR
South Korea
Prior art keywords
spacer
syringe
barrel
flange
fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020177010206A
Other languages
English (en)
Korean (ko)
Other versions
KR20170056645A (ko
Inventor
마크 씨. 차이
브라이언 엠. 2세 가톤
미첼 에프. 케인
이삭 제이. 칸
브렌덴 제이. 오버커체
다니엘 더불유. 프라이스
Original Assignee
자이로스코프 테라퓨틱스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 자이로스코프 테라퓨틱스 리미티드 filed Critical 자이로스코프 테라퓨틱스 리미티드
Publication of KR20170056645A publication Critical patent/KR20170056645A/ko
Application granted granted Critical
Publication of KR102202183B1 publication Critical patent/KR102202183B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3148—Means for causing or aiding aspiration or plunger retraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2086—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically having piston damping means, e.g. axially or rotationally acting retarders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A61M2005/3154—Blocking means to immobilize a selected dose, e.g. to administer equal doses limiting maximum permissible dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M2039/1077—Adapters, e.g. couplings adapting a connector to one or several other connectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
KR1020177010206A 2014-09-18 2015-09-16 치료제 전달 장치 Active KR102202183B1 (ko)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201462052074P 2014-09-18 2014-09-18
US201462052043P 2014-09-18 2014-09-18
US201462052038P 2014-09-18 2014-09-18
US201462052059P 2014-09-18 2014-09-18
US62/052,038 2014-09-18
US62/052,059 2014-09-18
US62/052,043 2014-09-18
US62/052,074 2014-09-18
US14/843,350 US10258502B2 (en) 2014-09-18 2015-09-02 Therapeutic agent delivery device
US14/843,350 2015-09-02
PCT/US2015/050394 WO2016044404A2 (en) 2014-09-18 2015-09-16 Therapeutic agent delivery device

Publications (2)

Publication Number Publication Date
KR20170056645A KR20170056645A (ko) 2017-05-23
KR102202183B1 true KR102202183B1 (ko) 2021-01-13

Family

ID=55524718

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177010206A Active KR102202183B1 (ko) 2014-09-18 2015-09-16 치료제 전달 장치

Country Status (14)

Country Link
US (2) US10258502B2 (enExample)
EP (1) EP3193987B1 (enExample)
JP (2) JP6772127B2 (enExample)
KR (1) KR102202183B1 (enExample)
CN (1) CN107223042B (enExample)
AU (1) AU2015317872B2 (enExample)
BR (1) BR112017005332B1 (enExample)
CA (1) CA2961529C (enExample)
MX (1) MX2017003616A (enExample)
PH (1) PH12017500502A1 (enExample)
RU (1) RU2704596C2 (enExample)
SG (1) SG11201702095XA (enExample)
WO (1) WO2016044404A2 (enExample)
ZA (1) ZA201702634B (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110680606B (zh) 2014-02-12 2023-07-21 陀螺仪治疗学有限公司 用于治疗剂的脉络膜上施用的方法和设备
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
CA2996197C (en) 2015-08-24 2019-07-16 Teleflex Medical Incorporated Dose divider syringe
US10478553B2 (en) 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
CN109310827B (zh) * 2016-04-08 2021-09-07 阿勒根公司 抽吸和注射装置
US10646374B2 (en) 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US11000410B2 (en) 2016-06-17 2021-05-11 Gyroscope Therapeutics Limited Guide apparatus for tangential entry into suprachoroidal space
US10806629B2 (en) 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
US11273072B2 (en) 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
US10463797B2 (en) 2017-09-07 2019-11-05 URO-1, Inc. Incremental syringe
US11090438B2 (en) 2017-10-17 2021-08-17 Bobby Nourani Slanted syringe handle
WO2019133492A1 (en) * 2017-12-29 2019-07-04 Becton, Dickinson And Company Low cost syringe with durable and disposable components
EP3749386A4 (en) 2018-02-09 2021-10-27 Icon Bioscience, Inc. SYSTEMS, KITS AND METHODS FOR LOADING AND DISPENSING A SMALL VOLUME DOSE FROM A SYRINGE
EP4197502B1 (en) 2018-04-12 2025-11-12 New World Medical, Inc. Device for intraocular fluid injection
EP3796950B1 (en) * 2018-05-22 2022-02-16 KCI Licensing, Inc. Systems for managing pneumatic pathways in integrated multilayer wound dressings
WO2020028847A1 (en) * 2018-08-02 2020-02-06 Bard Peripheral Vascular, Inc. Implantable port placement system including low-scarring exterior
US11759355B1 (en) 2019-02-26 2023-09-19 Gyroscope Therapeutics Limited Method of delivering leading blebs and agent to subretinal space
CN114555016B (zh) * 2019-10-11 2024-10-01 陀螺仪治疗学有限公司 用于注射器的剂量夹组件
USD987818S1 (en) 2019-12-04 2023-05-30 Bobby Nourani Syringe adaptor
MX2022011459A (es) * 2020-03-17 2022-10-07 Amgen Inc Jeringa de dispensacion controlada.
JP7488331B2 (ja) * 2020-03-24 2024-05-21 テルモ株式会社 注射器バレル用グリップおよびバレル組立体ならびにシリンジ
USD960359S1 (en) 2020-06-19 2022-08-09 Bobby Nourani Syringe handle
EP3967341B1 (en) * 2020-09-10 2025-07-09 Fenwal, Inc. Syringe with syringe closure
USD987819S1 (en) 2021-02-18 2023-05-30 Bobby Nourani Syringe holder
DE102021112962A1 (de) * 2021-05-19 2022-11-24 F+K Innovationen Gmbh & Co. Kg BI-Dose-Vorrichtung
IL309970A (en) 2021-07-22 2024-03-01 Chengdu Origen Biotechnology Co Ltd Eye injection assembly, injection device and method of using it
US20230125693A1 (en) * 2021-10-22 2023-04-27 Lisa Monique Staples Breathing circuit-to-laryngoscope adapter
WO2023172585A1 (en) * 2022-03-07 2023-09-14 The Johns Hopkins University Method and system for delivery of therapeutics to eye
WO2024013559A1 (en) 2022-07-11 2024-01-18 Gyroscope Therapeutics Limited Transvitreal subretinal injector
IL319330A (en) 2022-09-06 2025-05-01 Genentech Inc A device for subretinal administration of a therapeutic agent using a double curved needle
IL322034A (en) 2023-01-13 2025-09-01 Genentech Inc Syringe dosing station
TW202529711A (zh) 2023-09-29 2025-08-01 美商建南德克公司 眼插管導引器、施用器及標記器械
WO2025207699A1 (en) 2024-03-27 2025-10-02 Genentech, Inc. Torque ring for subretinal injection device
WO2025217214A2 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Recombinant adeno-associated viruses and uses thereof
WO2025217230A1 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Vectorized anti-complement antibodies and complement agents and administration thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013162989A (ja) 2012-02-13 2013-08-22 Nidek Co Ltd 医療用器具

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US287576A (en) * 1883-10-30 Sewing machine
US2875761A (en) 1956-10-01 1959-03-03 Norman D Helmer Multiple dosage syringe
US4267846A (en) * 1979-01-29 1981-05-19 Critikon, Inc. Controlled volume blood sampling syringe
US4231494A (en) * 1979-03-22 1980-11-04 Greenwood David L Syringe adaptor assembly
US4874385A (en) * 1987-12-16 1989-10-17 Sherwood Medical Company Plunger lock device
US5066276A (en) * 1988-06-21 1991-11-19 Alcon Laboratories, Inc. Method and apparatus for injecting viscous fluid into the eye to lift pre-retinal and post-retinal membrane with linear pressure control
US5019037A (en) * 1989-07-06 1991-05-28 Alcon Laboratories, Inc. Pneumatic retinopexy injector
US5817075A (en) * 1989-08-14 1998-10-06 Photogenesis, Inc. Method for preparation and transplantation of planar implants and surgical instrument therefor
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
US5252064A (en) * 1991-02-19 1993-10-12 Teledyne Industries, Inc. Subgingival irrigator
US5601077A (en) * 1991-08-07 1997-02-11 Becton, Dickinson And Company Nasal syringe sprayer with removable dose limiting structure
US5653715A (en) 1993-03-09 1997-08-05 Chiron Vision Corporation Apparatus for preparing an intraocular lens for insertion
US5803918A (en) * 1993-05-06 1998-09-08 Becton Dickinson And Company Syringe for medicinal purposes
DE4339528C2 (de) * 1993-11-19 1995-09-07 Freudenberg Carl Fa Einwegspritze
JP3306796B2 (ja) * 1995-01-26 2002-07-24 大成化工株式会社 薬液が予備充填された注入筒向けガラスカートリッジ
US5964740A (en) 1996-07-09 1999-10-12 Asahi Kogaku Kogyo Kabushiki Kaisha Treatment accessory for an endoscope
US6283951B1 (en) 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
ATE275880T1 (de) 1995-10-13 2004-10-15 Transvascular Inc Vorrichtung zur umgehung von arteriellen verengungen und/oder zur ausführung anderer transvaskularer eingriffe
US5887764A (en) * 1996-11-27 1999-03-30 Ennis, Iii; James F. Apparatus for a pressurized injector
US5975355A (en) * 1997-06-25 1999-11-02 Cecala; Ann Dosage unit measurer for syringe
DE19741487C2 (de) 1997-09-19 2000-08-31 Univ Eberhard Karls Vorrichtung für einen Zugang in den Subretinalraum eines Auges
US6200289B1 (en) 1998-04-10 2001-03-13 Milestone Scientific, Inc. Pressure/force computer controlled drug delivery system and the like
US6309374B1 (en) * 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
US6143004A (en) 1998-08-18 2000-11-07 Atrion Medical Products, Inc. Suturing device
US6162197A (en) 1998-12-22 2000-12-19 Mohammad; Owais Retractable needle assembly and method of making the same
JP3372886B2 (ja) 1999-02-18 2003-02-04 エスエムシー株式会社 管継手
US6368315B1 (en) 1999-06-23 2002-04-09 Durect Corporation Composite drug delivery catheter
DE60007593T2 (de) 1999-10-14 2004-11-11 Becton, Dickinson And Co. Nasales Verabreichungsgerät mit Zerstäuberdüse
DE60018777T2 (de) 1999-10-21 2006-02-02 Alcon Inc. Medikamentenversorgung der sub-tenon
US7357794B2 (en) 2002-01-17 2008-04-15 Medtronic Vascular, Inc. Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6989004B2 (en) 2001-02-28 2006-01-24 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
US7122042B2 (en) 2001-03-15 2006-10-17 Lorusso Frank J Apparatuses and methods for transcleral cautery and subretinal drainage
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US6494863B1 (en) 2001-10-15 2002-12-17 Retractable Technologies, Inc. One-use retracting syringe with positive needle retention
AU2003213075A1 (en) 2002-02-14 2003-09-04 Henry J. Kaplan Subretinal implantation device and surgical cannulas for use therewith
US7316676B2 (en) 2002-08-20 2008-01-08 Gholam A. Peyman Treatment of retinal detachment
WO2004028477A2 (en) 2002-09-29 2004-04-08 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US6997904B2 (en) * 2002-12-24 2006-02-14 Robert David Sculati Viscous fluid injection system
KR100473568B1 (ko) * 2003-01-25 2005-03-10 이희영 밀폐형 지방이식 시스템
US7329241B2 (en) 2003-02-14 2008-02-12 Valeant Pharmaceuticals North America Drug delivery system for administering an adjustable preset dose
US7220224B1 (en) * 2003-03-07 2007-05-22 Minu, Llc Retinal translocation and fixation using adhesive material
US20040199130A1 (en) 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
JP4289919B2 (ja) 2003-05-06 2009-07-01 朝日インテック株式会社 薬液注入装置
DE10326706A1 (de) * 2003-06-04 2005-01-05 Schott Ag Spritze, insbesondere für medizinische Anwendungen, sowie Verfahren zum Herstellen einer solchen
PL1641916T3 (pl) 2003-06-27 2016-08-31 Depuy Synthes Products Inc Regeneracja i naprawa tkanki nerwowej z wykorzystaniem komórek poporodowych
FR2858931B1 (fr) * 2003-08-21 2007-04-13 Becton Dickinson France Dispositif d'administration orale d'un medicament
AR042539A1 (es) * 2003-12-18 2005-06-22 Jose Santiago Rolla Unidad para suministro de inyectables en forma manual o automatica
PL1715827T3 (pl) 2004-01-23 2011-07-29 Iscience Interventional Corp Złożona okulistyczna mikrokaniula
US7563222B2 (en) * 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
US8235256B2 (en) * 2004-02-12 2012-08-07 Kyphon Sarl Manual pump mechanism and delivery system
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
US20100173866A1 (en) * 2004-04-29 2010-07-08 Iscience Interventional Corporation Apparatus and method for ocular treatment
US7601140B2 (en) * 2004-06-25 2009-10-13 Alcon, Inc. Syringe pressure applicator
JP2006010010A (ja) 2004-06-29 2006-01-12 Smc Corp 管継手
US20060047250A1 (en) 2004-08-30 2006-03-02 Hickingbotham Dyson W Fluid delivery device
US20060173415A1 (en) 2005-01-11 2006-08-03 Christy Cummins Syringe adaptor
US7686788B2 (en) * 2005-03-03 2010-03-30 Boston Scientific Scimed, Inc. Catheter having a distal drug delivery unit and method of using same
CN101171044B (zh) * 2005-05-02 2011-10-05 弹性体系统有限公司 以带无菌保护的注射针设备给药多剂量的注射器
WO2007002304A2 (en) 2005-06-22 2007-01-04 Vnus Medical Technologies, Inc. Methods and apparatus for introducing tumescent fluid to body tissue
US9144645B2 (en) * 2005-09-21 2015-09-29 Applied Diabetes Research, Inc. One piece sealing reservoir for an insulin infusion pump
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20080004596A1 (en) 2006-05-25 2008-01-03 Palo Alto Institute Delivery of agents by microneedle catheter
WO2007146921A2 (en) * 2006-06-13 2007-12-21 Nordson Corporation Liquid dispensing syringe
US20080281292A1 (en) 2006-10-16 2008-11-13 Hickingbotham Dyson W Retractable Injection Port
US20090124996A1 (en) * 2006-11-03 2009-05-14 Scott Heneveld Apparatus and methods for injecting high viscosity dermal fillers
JP2008142533A (ja) 2006-11-16 2008-06-26 Manii Kk トロカール
US20090018512A1 (en) * 2007-07-13 2009-01-15 Charles Steven T Pneumatically-Powered Ophthalmic Injector
US20090018548A1 (en) * 2007-07-13 2009-01-15 Charles Steven T Pneumatically-Powered Intraocular Lens Injection Device with Removable Cartridge
EP2227257B1 (en) 2008-01-07 2013-06-26 Salutaris Medical Devices, Inc. Devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye
WO2009089409A2 (en) 2008-01-10 2009-07-16 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
WO2009105690A2 (en) * 2008-02-21 2009-08-27 Targeted Genetics Corporation Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea
US7976510B2 (en) * 2008-02-28 2011-07-12 Becton, Dickinson And Company Syringe with adjustable two piece plunger rod
WO2009111645A1 (en) * 2008-03-05 2009-09-11 Ivantis, Inc. Methods and apparatus for treating glaucoma
EP2323566A2 (en) 2008-08-13 2011-05-25 Silk Road Medical, Inc. Suture delivery device
US8425473B2 (en) 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
EP2429607A4 (en) 2009-05-15 2014-01-08 Iscience Interventional Corp METHOD AND DEVICE FOR SUBRETINAL CATHETERIZATION
EP2437841B1 (en) 2009-06-05 2019-10-30 Cook Medical Technologies LLC Access sheath and needle assembly for delivering therapeutic material
US20110087173A1 (en) * 2009-10-12 2011-04-14 Sibbitt Jr Wilmer L Automatic syringes
EP2496304A4 (en) 2009-11-02 2013-04-17 Salutaris Medical Devices Inc METHOD AND DEVICES FOR THE ADMINISTRATION OF MINIMALLY INVASIVE EXTRACOLAR RADIATION
CH702815A1 (de) * 2010-03-10 2011-09-15 Medmix Systems Ag Befüllvorrichtung zum Befüllen mindestens eines ersten Reservoirs eines Applikators.
SE535983C2 (sv) * 2010-04-20 2013-03-19 Noviscens Ab Spruta
CN103025376B (zh) * 2010-06-30 2016-03-30 尼普洛株式会社 喷雾器
AU2011310580C1 (en) * 2010-10-01 2016-03-10 Bracco Imaging Spa Finger-grip device for medical syringe or cartridge
US20120271272A1 (en) 2010-10-15 2012-10-25 Iscience Interventional Corporation Device for ocular access
BR112013027428B1 (pt) * 2011-04-25 2021-05-18 Icon Bioscience, Inc. sistema guia de distribuição de dose e carregamento de dose duplo para seringa de injeção, kit que compreende tal sistema, e método para uso do sistema de distribuição de dose e carregamento de dose duplo
JP5695485B2 (ja) * 2011-04-28 2015-04-08 株式会社吉野工業所 注射器
JP6538350B2 (ja) 2011-04-28 2019-07-03 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． 分配デバイスのためのリミッター
JP5858042B2 (ja) * 2011-05-13 2016-02-10 ニプロ株式会社 鼻腔投与容器
US8852165B2 (en) 2011-06-16 2014-10-07 II Edward G. Mackay Endoluminal drug delivery devices and methods
US9629675B2 (en) 2011-10-19 2017-04-25 Confluent Medical Technologies, Inc. Tissue treatment device and related methods
US20130131633A1 (en) * 2011-11-18 2013-05-23 Allergan, Inc. Modular injection system and method for diluting an injectable fluid
WO2013123309A1 (en) 2012-02-15 2013-08-22 The Cleveland Clinic Foundation Catheter assembly and method of treating a vascular disease
WO2014036009A1 (en) 2012-08-27 2014-03-06 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using microneedles
US9132229B2 (en) * 2012-09-13 2015-09-15 Alcon Research, Ltd. System and method of priming a surgical cassette
US9301795B2 (en) 2012-10-29 2016-04-05 Ablative Solutions, Inc. Transvascular catheter for extravascular delivery
CN110893188A (zh) 2012-11-08 2020-03-20 克莱尔塞德生物医学股份有限公司 用于在人类受试者中治疗眼部疾病的方法和装置
PL2732770T3 (pl) 2012-11-16 2016-12-30 Bezigłowe urządzenie do iniekcji
WO2014110624A1 (en) * 2013-01-15 2014-07-24 Heriot Wilson J Method and device for treating retinal detachment
WO2014153085A1 (en) * 2013-03-14 2014-09-25 Gavis Pharmaceuticals, Llc Syringe
US20160143776A1 (en) 2013-08-02 2016-05-26 Tel Hashomer Medical Research Infrastructure And Services Ltd. A device for delivery of compositions to the eye
US9795503B2 (en) * 2013-10-18 2017-10-24 Rodolfo Alfredo PEREZ GROSSMANN Method and apparatus for trabeculectomy and suprachoroidal shunt surgery
CN110680606B (zh) 2014-02-12 2023-07-21 陀螺仪治疗学有限公司 用于治疗剂的脉络膜上施用的方法和设备
US9925088B2 (en) 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
US9949874B2 (en) * 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
KR102511477B1 (ko) 2014-06-17 2023-03-16 클리어사이드 바이오메디컬, 인코포레이드 안구 후부 질환을 치료하기 위한 방법 및 디바이스
RU2710491C2 (ru) 2014-06-20 2019-12-26 Клиасайд Байомедикал, Инк. Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань
US10064752B2 (en) 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10322028B2 (en) 2014-09-11 2019-06-18 Orbit Biomedical Limited Method and apparatus for sensing position between layers of an eye
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
GB201516066D0 (en) 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013162989A (ja) 2012-02-13 2013-08-22 Nidek Co Ltd 医療用器具

Also Published As

Publication number Publication date
RU2017113086A (ru) 2018-10-18
JP6953580B2 (ja) 2021-10-27
CA2961529A1 (en) 2016-03-24
WO2016044404A2 (en) 2016-03-24
US11337852B2 (en) 2022-05-24
WO2016044404A3 (en) 2016-06-09
MX2017003616A (es) 2018-01-24
RU2704596C2 (ru) 2019-10-29
ZA201702634B (en) 2019-06-26
US10258502B2 (en) 2019-04-16
CN107223042A (zh) 2017-09-29
KR20170056645A (ko) 2017-05-23
EP3193987A2 (en) 2017-07-26
CA2961529C (en) 2021-08-31
SG11201702095XA (en) 2017-04-27
AU2015317872B2 (en) 2019-12-19
PH12017500502A1 (en) 2017-08-30
BR112017005332A2 (pt) 2017-12-12
US20190183674A1 (en) 2019-06-20
CN107223042B (zh) 2020-02-21
RU2017113086A3 (enExample) 2019-06-14
JP2020121196A (ja) 2020-08-13
JP6772127B2 (ja) 2020-10-21
EP3193987B1 (en) 2020-02-26
BR112017005332B1 (pt) 2022-04-12
AU2015317872A1 (en) 2017-04-06
JP2017527406A (ja) 2017-09-21
US20160081849A1 (en) 2016-03-24

Similar Documents

Publication Publication Date Title
KR102202183B1 (ko) 치료제 전달 장치
US20250318953A1 (en) Therapeutic agent delivery device with convergent lumen
US11723798B2 (en) Sub-retinal tangential needle catheter guide and introducer
JP7023873B2 (ja) 湾曲した針を介する治療剤の網膜下投与のための装置
JP2017505686A (ja) 治療薬の脈絡膜上投与のための方法及び装置
JP7455962B2 (ja) シリンジのための投薬クリップ組立体

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20170414

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PN2301 Change of applicant

Patent event date: 20180928

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20200915

Comment text: Request for Examination of Application

PA0302 Request for accelerated examination

Patent event date: 20200915

Patent event code: PA03022R01D

Comment text: Request for Accelerated Examination

N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 20201005

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20201026

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20210107

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20210108

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20241224

Start annual number: 5

End annual number: 5