KR102171028B1 - 비 병원성 f18 대장균 균주 및 이의 용도 - Google Patents

비 병원성 f18 대장균 균주 및 이의 용도 Download PDF

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KR102171028B1
KR102171028B1 KR1020157004177A KR20157004177A KR102171028B1 KR 102171028 B1 KR102171028 B1 KR 102171028B1 KR 1020157004177 A KR1020157004177 A KR 1020157004177A KR 20157004177 A KR20157004177 A KR 20157004177A KR 102171028 B1 KR102171028 B1 KR 102171028B1
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KR20150036698A (ko
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존 모리스 페어브라더
에릭 네이도
클라리세 데소텔스
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프레브테크 마이크로비아 인코포레이티드
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • C12R1/19
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020157004177A 2012-07-20 2013-07-18 비 병원성 f18 대장균 균주 및 이의 용도 Active KR102171028B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261674179P 2012-07-20 2012-07-20
US61/674,179 2012-07-20
PCT/CA2013/000660 WO2014012172A1 (en) 2012-07-20 2013-07-18 Non-pathogenic f18 e. coli strain and use thereof

Publications (2)

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KR20150036698A KR20150036698A (ko) 2015-04-07
KR102171028B1 true KR102171028B1 (ko) 2020-10-28

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US (3) US9453195B2 (enExample)
EP (1) EP2875121B1 (enExample)
JP (1) JP6278960B2 (enExample)
KR (1) KR102171028B1 (enExample)
CN (1) CN104736695B (enExample)
BR (1) BR112015001175B1 (enExample)
CA (1) CA2879155C (enExample)
DK (1) DK2875121T3 (enExample)
ES (1) ES2663019T3 (enExample)
HU (1) HUE036545T2 (enExample)
MX (1) MX363057B (enExample)
PH (1) PH12015500091B1 (enExample)
PL (1) PL2875121T3 (enExample)
PT (1) PT2875121T (enExample)
RS (1) RS57056B1 (enExample)
RU (1) RU2670882C9 (enExample)
WO (1) WO2014012172A1 (enExample)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
HUE036545T2 (hu) 2012-07-20 2018-07-30 Prevtec Microbia Inc Nem-patogén F18 E. coli törzs és alkalmazása
JP6731416B2 (ja) * 2015-02-11 2020-07-29 プレヴテック マイクロビア インコーポレイテッド 生きている大腸菌を埋め込むための改良された乾燥マトリクス、その製造方法及びその使用
KR101715625B1 (ko) * 2015-06-02 2017-03-13 대한민국(농림축산식품부 농림축산검역본부장) 부종병 독소를 생산하는 대장균, 이를 이용한 부종병 독소의 생산방법 및 이를 포함하는 돼지 부종병 예방용 백신 조성물
RU2749883C2 (ru) * 2016-06-14 2021-06-18 Эланко Кэнэда Лимитед Гранулированный корм для животных, содержащий кормовую добавку, способ его получения и применения
WO2019006246A1 (en) * 2017-06-30 2019-01-03 The Rockefeller University N-ACYL AMIDES DERIVED FROM THE HUMAN MICROBIOTE FOR THE TREATMENT OF A HUMAN DISEASE
CN107523529B (zh) * 2017-10-20 2021-03-12 林州中农颖泰生物肽有限公司 一种利用大肠杆菌生产肠杆菌肽的工艺及其应用
CN109628361B (zh) * 2018-11-27 2022-08-19 扬州大学 整合双拷贝功能性f4菌毛操纵子基因猪源益生菌ep1克隆株、构建方法及应用
CN109504643B (zh) * 2018-11-27 2022-06-10 扬州大学 整合四拷贝功能性f18菌毛操纵子基因的益生菌克隆株、构建方法及应用
CN114752531B (zh) * 2022-04-29 2023-05-26 扬州大学 一株同时表达f4和f18菌毛的猪源大肠杆菌无毒分离株及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002043649A2 (en) 2000-11-30 2002-06-06 The Bio Balance Corp. Preparation of compositions comprising bacterial strains and volatile plant extracts and therapeutic and industrial applications thereof
US7163820B1 (en) 1999-03-31 2007-01-16 Mta Allatorvos-Tudomanyi K.I. Escherichia coli strain for an oral vaccine against post-weaning diarrhea in pigs
US20110318379A1 (en) 2008-07-08 2011-12-29 South Dakota State University Vaccine for Porcine Post-Weaning Diarrhea Caused by Enterotoxigenic Escherichia Coli

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RU2125455C1 (ru) * 1996-09-25 1999-01-27 Саратовская научно-исследовательская ветеринарная станция Способ профилактики диареи молодняка сельскохозяйственных животных
US6355859B1 (en) 1997-05-20 2002-03-12 Biotechnology Research And Development Corporation Interactions between genotype and diet in swine that prevent E. coli associated intestinal disease
US5965128A (en) * 1997-08-13 1999-10-12 University Of Georgia Research Foundation Inc. Control of enterohemorrhagic E. coli 0157:H7 in cattle by probiotic bacteria and specific strains of E. coli
WO2000006764A1 (en) * 1998-07-30 2000-02-10 Wisconsin Alumni Research Foundation Gastrointestinal bacterial antibody factories
US6304216B1 (en) 1999-03-30 2001-10-16 Conexant Systems, Inc. Signal detector employing correlation analysis of non-uniform and disjoint sample segments
IL130303A0 (en) * 1999-06-03 2000-06-01 M G Novobiotech Ltd A bacterial strain processed plant extracts and probiotic compositions for human and veterinary use
AU2003287028B2 (en) 2002-10-04 2008-09-04 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
WO2005074706A1 (en) * 2004-02-03 2005-08-18 Universite De Montreal Use of live bacteria for growth promotion in animals
MXPA06013253A (es) * 2004-05-14 2007-02-28 Agtech Products Inc Metodo y composicion para reducir la enfermedad de e. coli disease y mejorar el rendimiento utilizando bacilos.
HUE036545T2 (hu) 2012-07-20 2018-07-30 Prevtec Microbia Inc Nem-patogén F18 E. coli törzs és alkalmazása

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7163820B1 (en) 1999-03-31 2007-01-16 Mta Allatorvos-Tudomanyi K.I. Escherichia coli strain for an oral vaccine against post-weaning diarrhea in pigs
WO2002043649A2 (en) 2000-11-30 2002-06-06 The Bio Balance Corp. Preparation of compositions comprising bacterial strains and volatile plant extracts and therapeutic and industrial applications thereof
US20110318379A1 (en) 2008-07-08 2011-12-29 South Dakota State University Vaccine for Porcine Post-Weaning Diarrhea Caused by Enterotoxigenic Escherichia Coli

Also Published As

Publication number Publication date
EP2875121A1 (en) 2015-05-27
MX2015000905A (es) 2015-09-28
HUE036545T2 (hu) 2018-07-30
CN104736695B (zh) 2017-05-24
WO2014012172A1 (en) 2014-01-23
US20160361369A1 (en) 2016-12-15
US20180008651A1 (en) 2018-01-11
CA2879155A1 (en) 2014-01-23
RU2670882C2 (ru) 2018-10-25
PT2875121T (pt) 2018-03-14
PH12015500091A1 (en) 2015-03-02
US9775867B2 (en) 2017-10-03
EP2875121B1 (en) 2018-01-03
JP6278960B2 (ja) 2018-02-14
PL2875121T3 (pl) 2018-06-29
KR20150036698A (ko) 2015-04-07
US9453195B2 (en) 2016-09-27
US10258654B2 (en) 2019-04-16
BR112015001175B1 (pt) 2022-03-03
RS57056B1 (sr) 2018-05-31
HK1209780A1 (en) 2016-04-08
RU2670882C9 (ru) 2018-12-11
ES2663019T3 (es) 2018-04-10
BR112015001175A2 (pt) 2017-06-27
DK2875121T3 (en) 2018-04-16
RU2015105738A (ru) 2016-09-10
CN104736695A (zh) 2015-06-24
US20150152377A1 (en) 2015-06-04
PH12015500091B1 (en) 2015-03-02
CA2879155C (en) 2024-04-30
JP2015525566A (ja) 2015-09-07
EP2875121A4 (en) 2016-01-13
MX363057B (es) 2019-03-06

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