KR102148866B1 - 암 치료를 위한 t 세포의 활성화 방법 - Google Patents
암 치료를 위한 t 세포의 활성화 방법 Download PDFInfo
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- KR102148866B1 KR102148866B1 KR1020180093946A KR20180093946A KR102148866B1 KR 102148866 B1 KR102148866 B1 KR 102148866B1 KR 1020180093946 A KR1020180093946 A KR 1020180093946A KR 20180093946 A KR20180093946 A KR 20180093946A KR 102148866 B1 KR102148866 B1 KR 102148866B1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/869—Herpesviral vectors
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6056—Antibodies
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
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- C12N2710/16011—Herpesviridae
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- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
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- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
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- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
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- Mycology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020170101800 | 2017-08-10 | ||
| KR20170101800 | 2017-08-10 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020200105269A Division KR20200102402A (ko) | 2017-08-10 | 2020-08-21 | 암 치료를 위한 t 세포의 활성화 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20190017705A KR20190017705A (ko) | 2019-02-20 |
| KR102148866B1 true KR102148866B1 (ko) | 2020-10-14 |
Family
ID=65271692
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020180093946A Active KR102148866B1 (ko) | 2017-08-10 | 2018-08-10 | 암 치료를 위한 t 세포의 활성화 방법 |
| KR1020180093897A Active KR102190890B1 (ko) | 2017-08-10 | 2018-08-10 | 암 치료를 위한 t 세포의 활성화 방법 |
| KR1020200105269A Withdrawn KR20200102402A (ko) | 2017-08-10 | 2020-08-21 | 암 치료를 위한 t 세포의 활성화 방법 |
| KR1020200170517A Ceased KR20200141424A (ko) | 2017-08-10 | 2020-12-08 | 암 치료를 위한 t 세포의 활성화 방법 |
| KR1020220114288A Ceased KR20220136957A (ko) | 2017-08-10 | 2022-09-08 | 암 치료를 위한 t 세포의 활성화 방법 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020180093897A Active KR102190890B1 (ko) | 2017-08-10 | 2018-08-10 | 암 치료를 위한 t 세포의 활성화 방법 |
| KR1020200105269A Withdrawn KR20200102402A (ko) | 2017-08-10 | 2020-08-21 | 암 치료를 위한 t 세포의 활성화 방법 |
| KR1020200170517A Ceased KR20200141424A (ko) | 2017-08-10 | 2020-12-08 | 암 치료를 위한 t 세포의 활성화 방법 |
| KR1020220114288A Ceased KR20220136957A (ko) | 2017-08-10 | 2022-09-08 | 암 치료를 위한 t 세포의 활성화 방법 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11918634B2 (https=) |
| EP (2) | EP3666887A4 (https=) |
| JP (3) | JP7693189B2 (https=) |
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| JP2022519378A (ja) * | 2019-02-08 | 2022-03-23 | グッド ティー セルズ、 インコーポレイテッド | がん治療のためのt細胞の活性化方法 |
| WO2020170254A1 (en) * | 2019-02-21 | 2020-08-27 | Ramot At Tel-Aviv University Ltd. | Treatment of diseases with multimeric peptides |
| KR102182555B1 (ko) * | 2019-03-14 | 2020-11-24 | 한국과학기술연구원 | T 세포 면역 반응 활성화를 위한 암 치료용 암항원 발굴 플랫폼 |
| KR102322832B1 (ko) * | 2019-04-22 | 2021-11-12 | 한국과학기술연구원 | 인간 백혈구 항원 a24:02 대립유전자에 특이적으로 결합하는 펩타이드 및 이의 용도 |
| KR102335916B1 (ko) * | 2019-04-22 | 2021-12-08 | 한국과학기술연구원 | 인간 백혈구 항원 a02:01 대립유전자에 특이적으로 결합하는 펩타이드 및 이의 용도 |
| US20220364079A1 (en) * | 2019-09-23 | 2022-11-17 | Dana-Farber Cancer Institute, Inc. | Methods of high-throughput identification of t cell epitopes by capturing cytokines on the surface of antigen-presenting cells |
| KR20210102089A (ko) | 2020-02-11 | 2021-08-19 | 주식회사 리스큐어바이오사이언시스 | 미성숙 수지상 세포의 성숙화 유도를 이용한 암의 예방 또는 치료용 조성물 |
| CN116018158A (zh) * | 2020-04-30 | 2023-04-25 | 转化基因组学研究所 | 新抗原知情的肿瘤浸润性淋巴细胞癌免疫疗法 |
| GB202010095D0 (en) * | 2020-07-01 | 2020-08-12 | Tcer Ab | Immunotherapy |
| KR20220118225A (ko) | 2021-02-18 | 2022-08-25 | 주식회사 리스큐어바이오사이언시스 | 미성숙 수지상 세포의 성숙화 유도를 이용한 암의 예방 또는 치료용 조성물 |
| KR20220131170A (ko) | 2021-03-19 | 2022-09-27 | 주식회사 리스큐어바이오사이언시스 | 미성숙 수지상 세포의 성숙화 유도를 이용한 암의 예방 또는 치료용 조성물 |
| CN113321724B (zh) * | 2021-03-24 | 2022-02-01 | 深圳市新靶向生物科技有限公司 | 一种与食道癌驱动基因突变相关的抗原肽及其应用 |
| WO2023227085A1 (zh) * | 2022-05-26 | 2023-11-30 | 苏州尔生生物医药有限公司 | 用于预防或治疗癌症的特异性t细胞及其制备方法 |
| WO2024151124A1 (ko) * | 2023-01-12 | 2024-07-18 | 주식회사 이뮤노맥스 | 항암능이 우수한 기억 t 세포 유래 면역세포치료제의 제조방법 |
| WO2025240737A1 (en) * | 2024-05-16 | 2025-11-20 | Rutgers, The State University Of New Jersey | Methods of producing memory t cells in vitro and their use in immunotherapy |
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| WO2016203577A1 (ja) | 2015-06-17 | 2016-12-22 | 株式会社医学生物学研究所 | 細胞傷害性t細胞エピトープペプチド及びその用途 |
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| WO2019031938A2 (ko) | 2019-02-14 |
| EP3666887A4 (en) | 2021-09-01 |
| US11918634B2 (en) | 2024-03-05 |
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| JP7364237B2 (ja) | 2023-10-18 |
| JP7693189B2 (ja) | 2025-06-17 |
| WO2019031939A2 (ko) | 2019-02-14 |
| EP3666888A2 (en) | 2020-06-17 |
| BR112020002816A2 (pt) | 2020-08-04 |
| JP2023113855A (ja) | 2023-08-16 |
| CN110997903A (zh) | 2020-04-10 |
| US20210009952A1 (en) | 2021-01-14 |
| KR20200102402A (ko) | 2020-08-31 |
| US20200289630A1 (en) | 2020-09-17 |
| KR102190890B1 (ko) | 2020-12-15 |
| KR20190017705A (ko) | 2019-02-20 |
| CN110997903B (zh) | 2024-03-29 |
| KR20190017702A (ko) | 2019-02-20 |
| JP2020532956A (ja) | 2020-11-19 |
| WO2019031939A3 (ko) | 2019-07-18 |
| KR20200141424A (ko) | 2020-12-18 |
| EP3666888A4 (en) | 2021-09-01 |
| WO2019031938A3 (ko) | 2019-07-04 |
| KR20220136957A (ko) | 2022-10-11 |
| CN111433355B (zh) | 2024-03-29 |
| JP2020532957A (ja) | 2020-11-19 |
| US11969463B2 (en) | 2024-04-30 |
| CN111433355A (zh) | 2020-07-17 |
| EP3666887A2 (en) | 2020-06-17 |
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