WO2019031939A3 - 암 치료를 위한 t 세포의 활성화 방법 - Google Patents

암 치료를 위한 t 세포의 활성화 방법 Download PDF

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WO2019031939A3
WO2019031939A3 PCT/KR2018/009225 KR2018009225W WO2019031939A3 WO 2019031939 A3 WO2019031939 A3 WO 2019031939A3 KR 2018009225 W KR2018009225 W KR 2018009225W WO 2019031939 A3 WO2019031939 A3 WO 2019031939A3
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cells
cancer
antigen
activating
presenting cell
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WO2019031939A2 (ko
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김정호
김범석
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주식회사 굳티셀
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Priority to US16/637,927 priority Critical patent/US11969463B2/en
Priority to EP18843560.6A priority patent/EP3666887A4/en
Priority to JP2020507103A priority patent/JP2020532957A/ja
Priority to CN201880052033.7A priority patent/CN111433355B/zh
Publication of WO2019031939A2 publication Critical patent/WO2019031939A2/ko
Publication of WO2019031939A3 publication Critical patent/WO2019031939A3/ko
Priority to JP2023093867A priority patent/JP2023113855A/ja

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Abstract

서열번호 1 내지 214 중 어느 하나로 표시되는 암 특이적 네오-에피토프(neo-epitope), 상기 네오-에피토프가 로딩된 항원 제시 세포, 및 상기 항원 제시 세포에 의해 암 치료를 위한 T 세포를 활성화하는 방법에 관한 것이다. 본 발명에서 제공하는 암 특이적 에피토프가 로딩된 항원 제시 세포, 즉 수지상 세포를 통해 암 항원 특이적인 T 세포, 바람직하게는 메모리 T 세포의 분화 및 증식을 빠르고 효과적으로 유도할 수 있고, 이렇게 활성화된 메모리 T 세포는 암 세포의 방어 기작을 피해 암 또는 종양성 상태를 치료하거나 암의 재발, 진행 또는 전이를 예방할 수 있다.
PCT/KR2018/009225 2017-08-10 2018-08-10 암 치료를 위한 t 세포의 활성화 방법 WO2019031939A2 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US16/637,927 US11969463B2 (en) 2017-08-10 2018-08-10 Method for activating T cells for cancer treatment
EP18843560.6A EP3666887A4 (en) 2017-08-10 2018-08-10 METHOD OF ACTIVATING T CELLS FOR CANCER TREATMENT
JP2020507103A JP2020532957A (ja) 2017-08-10 2018-08-10 癌治療のためのｔ細胞の活性化方法
CN201880052033.7A CN111433355B (zh) 2017-08-10 2018-08-10 用于癌症治疗的t细胞的活化方法
JP2023093867A JP2023113855A (ja) 2017-08-10 2023-06-07 癌治療のためのｔ細胞の活性化方法

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KR20170101800 2017-08-10
KR10-2017-0101800 2017-08-10

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WO2019031939A2 WO2019031939A2 (ko) 2019-02-14
WO2019031939A3 true WO2019031939A3 (ko) 2019-07-18

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