KR102143887B1 - Toso 활성을 조절하기 위한 방법 및 조성물 - Google Patents

Toso 활성을 조절하기 위한 방법 및 조성물 Download PDF

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KR102143887B1
KR102143887B1 KR1020147028977A KR20147028977A KR102143887B1 KR 102143887 B1 KR102143887 B1 KR 102143887B1 KR 1020147028977 A KR1020147028977 A KR 1020147028977A KR 20147028977 A KR20147028977 A KR 20147028977A KR 102143887 B1 KR102143887 B1 KR 102143887B1
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KR20150003197A (ko
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마이클 더블유. 투슈
탁 더블유. 막
파멜라 에스. 오하시
필립 랑
칼 랑
더크 브래너
글로리아 린
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유니버시티 헬스 네트워크
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
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    • A61P17/04—Antipruritics
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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KR1020147028977A 2012-03-16 2013-03-14 Toso 활성을 조절하기 위한 방법 및 조성물 Expired - Fee Related KR102143887B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261612183P 2012-03-16 2012-03-16
US61/612,183 2012-03-16
US201261646143P 2012-05-11 2012-05-11
US61/646,143 2012-05-11
US201261731428P 2012-11-29 2012-11-29
US61/731,428 2012-11-29
PCT/IB2013/001179 WO2013136193A2 (en) 2012-03-16 2013-03-14 Methods and compositions for modulating toso activity

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KR20150003197A KR20150003197A (ko) 2015-01-08
KR102143887B1 true KR102143887B1 (ko) 2020-08-12

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US (5) US9228006B2 (enExample)
EP (2) EP2825191B1 (enExample)
JP (3) JP6200437B2 (enExample)
KR (1) KR102143887B1 (enExample)
CN (1) CN104394880B (enExample)
AU (3) AU2013234046B2 (enExample)
CA (1) CA2867444C (enExample)
IL (1) IL234683B (enExample)
WO (1) WO2013136193A2 (enExample)

Families Citing this family (9)

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KR102143887B1 (ko) 2012-03-16 2020-08-12 유니버시티 헬스 네트워크 Toso 활성을 조절하기 위한 방법 및 조성물
CA2917077A1 (en) * 2013-07-03 2015-01-08 University Health Network Antibodies to toso
CA2933200C (en) * 2014-01-15 2025-05-06 Medimmune Limited RSV-SPECIFIC ANTIBODIES AND THEIR FUNCTIONAL PARTS
JP6538707B2 (ja) * 2014-03-07 2019-07-03 ユニバーシティ ヘルス ネットワーク 免疫応答を調節するための方法及び組成物
EP3009841A1 (en) * 2014-10-14 2016-04-20 Bernhard-Nocht-Institut für Tropenmedizin Detection of IgM Antibodies using an immune complex (IC) ELISA
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ES2690420T3 (es) 2015-05-28 2018-11-20 Universität Zu Köln Receptor de antígeno quimérico anti-toso y su uso
EP3911680A4 (en) 2019-01-18 2022-09-07 University Health Network LILRB3 BINDING MOLECULES AND ASSOCIATED USES
AU2020222408A1 (en) * 2019-02-15 2021-09-09 University Health Network FCMR-binding molecules and uses thereof

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JP2019054821A (ja) 2019-04-11
US9321824B2 (en) 2016-04-26
AU2013234046A1 (en) 2014-10-09
JP6462800B2 (ja) 2019-01-30
US9670265B2 (en) 2017-06-06
EP3626254A1 (en) 2020-03-25
IL234683B (en) 2020-02-27
CA2867444A1 (en) 2013-09-19
AU2013234046B2 (en) 2017-09-07
CN104394880B (zh) 2020-08-28
US20150197551A1 (en) 2015-07-16
WO2013136193A3 (en) 2014-01-16
JP2015511599A (ja) 2015-04-20
US9228006B2 (en) 2016-01-05
JP2018027951A (ja) 2018-02-22
JP6200437B2 (ja) 2017-09-20
US20180016320A1 (en) 2018-01-18
CA2867444C (en) 2021-04-13
JP6744391B2 (ja) 2020-08-19
CN104394880A (zh) 2015-03-04
US10822388B2 (en) 2020-11-03
EP2825191A2 (en) 2015-01-21
WO2013136193A8 (en) 2014-05-08
EP2825191B1 (en) 2019-08-28
US20130281356A1 (en) 2013-10-24
AU2019204594B2 (en) 2021-05-06
AU2017272172B2 (en) 2019-04-04
AU2017272172A1 (en) 2017-12-21
US20150139995A1 (en) 2015-05-21
KR20150003197A (ko) 2015-01-08
US9624289B2 (en) 2017-04-18
WO2013136193A2 (en) 2013-09-19

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