KR102136437B1 - 재조합체 btv 및 ahsv 백신 - Google Patents

재조합체 btv 및 ahsv 백신 Download PDF

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KR102136437B1
KR102136437B1 KR1020157000827A KR20157000827A KR102136437B1 KR 102136437 B1 KR102136437 B1 KR 102136437B1 KR 1020157000827 A KR1020157000827 A KR 1020157000827A KR 20157000827 A KR20157000827 A KR 20157000827A KR 102136437 B1 KR102136437 B1 KR 102136437B1
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KR20150036057A (ko
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마시모 팔마리니
파스칼 우델레트
쟝-크리스토쁘 오도네
상드로 필리쁘 뉘네
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뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드
더 유니버시티 코트 오브 더 유니버시티 오브 글래스고우
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
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    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12121Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12171Demonstrated in vivo effect

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020157000827A 2012-06-13 2013-06-13 재조합체 btv 및 ahsv 백신 Active KR102136437B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261659198P 2012-06-13 2012-06-13
US61/659,198 2012-06-13
PCT/US2013/045667 WO2013188673A2 (en) 2012-06-13 2013-06-13 Reassortant btv and ahsv vaccines

Publications (2)

Publication Number Publication Date
KR20150036057A KR20150036057A (ko) 2015-04-07
KR102136437B1 true KR102136437B1 (ko) 2020-07-21

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US (1) US10801039B2 (enExample)
EP (1) EP2861248B1 (enExample)
JP (1) JP6347257B2 (enExample)
KR (1) KR102136437B1 (enExample)
CN (2) CN110628822A (enExample)
AU (2) AU2013274191B2 (enExample)
BR (1) BR112014031133B1 (enExample)
CA (1) CA2876196C (enExample)
ES (1) ES2664069T3 (enExample)
IL (1) IL236148B (enExample)
MA (1) MA37749B1 (enExample)
MX (1) MX364875B (enExample)
NZ (1) NZ703297A (enExample)
RU (1) RU2656187C2 (enExample)
TN (1) TN2014000518A1 (enExample)
WO (1) WO2013188673A2 (enExample)
ZA (1) ZA201409124B (enExample)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
EP3445860A1 (en) 2016-04-19 2019-02-27 Csir Plant-produced chimaeric orbivirus vlps
WO2017187131A1 (en) 2016-04-26 2017-11-02 London School Of Hygiene & Tropical Medicine Reoviridae vaccine
CN110049994B (zh) * 2016-12-08 2023-05-02 拜西欧斯(北京)生物技术有限公司 一种缀合物及其应用
CN109897092B (zh) * 2019-04-02 2019-11-19 深圳海关动植物检验检疫技术中心 一种蓝舌病病毒非结构蛋白ns3的可溶制备方法
CN110016466B (zh) * 2019-05-21 2022-09-13 云南省畜牧兽医科学院 特异性检测蓝舌病病毒的单抗及其杂交瘤细胞株和应用
CN110257560B (zh) * 2019-07-23 2023-06-27 深圳海关动植物检验检疫技术中心 一种用于蓝舌病病毒8型检测的试剂、检测方法及应用
CN112375848A (zh) * 2020-12-11 2021-02-19 云南省畜牧兽医科学院 一种蓝舌病病毒血清型鉴定的RT-qPCR检测试剂盒和方法
CN117363588B (zh) * 2023-02-15 2024-08-30 中国农业科学院兰州兽医研究所 一种表达四半胱氨酸标签重组蓝舌病毒的制备方法及应用

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Also Published As

Publication number Publication date
IL236148A0 (en) 2015-01-29
BR112014031133A2 (enExample) 2017-08-15
TN2014000518A1 (en) 2016-03-30
CN110628822A (zh) 2019-12-31
AU2016235036A1 (en) 2016-10-27
IL236148B (en) 2019-05-30
CN104582724A (zh) 2015-04-29
AU2013274191A1 (en) 2015-01-22
AU2013274191B2 (en) 2016-09-22
CA2876196A1 (en) 2013-12-19
RU2015100269A (ru) 2016-08-10
CA2876196C (en) 2021-09-21
BR112014031133B1 (pt) 2023-02-07
WO2013188673A2 (en) 2013-12-19
ES2664069T3 (es) 2018-04-18
US10801039B2 (en) 2020-10-13
EP2861248B1 (en) 2017-11-15
JP6347257B2 (ja) 2018-06-27
MX364875B (es) 2019-05-09
RU2656187C2 (ru) 2018-05-31
JP2015525076A (ja) 2015-09-03
KR20150036057A (ko) 2015-04-07
NZ703297A (en) 2016-04-29
MA37749A1 (fr) 2016-08-31
EP2861248A2 (en) 2015-04-22
US20130337010A1 (en) 2013-12-19
MA37749B1 (fr) 2017-05-31
WO2013188673A3 (en) 2014-03-27
ZA201409124B (en) 2017-05-31
MX2014015311A (es) 2016-04-04
HK1209326A1 (en) 2016-04-01

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