KR102136437B1 - 재조합체 ｂｔｖ 및 ａｈｓｖ 백신 - Google Patents

재조합체 ｂｔｖ 및 ａｈｓｖ 백신 Download PDF

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KR102136437B1
KR102136437B1 KR1020157000827A KR20157000827A KR102136437B1 KR 102136437 B1 KR102136437 B1 KR 102136437B1 KR 1020157000827 A KR1020157000827 A KR 1020157000827A KR 20157000827 A KR20157000827 A KR 20157000827A KR 102136437 B1 KR102136437 B1 KR 102136437B1
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KR20150036057A (ko
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마시모 팔마리니
파스칼 우델레트
쟝-크리스토쁘 오도네
상드로 필리쁘 뉘네
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뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드
더 유니버시티 코트 오브 더 유니버시티 오브 글래스고우
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • C—CHEMISTRY; METALLURGY
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    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
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    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12171—Demonstrated in vivo effect

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  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
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  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020157000827A 2012-06-13 2013-06-13 재조합체 ｂｔｖ 및 ａｈｓｖ 백신 Active KR102136437B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261659198P 2012-06-13 2012-06-13
US61/659,198 2012-06-13
PCT/US2013/045667 WO2013188673A2 (en) 2012-06-13 2013-06-13 Reassortant btv and ahsv vaccines

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Publication Number Publication Date
KR20150036057A KR20150036057A (ko) 2015-04-07
KR102136437B1 true KR102136437B1 (ko) 2020-07-21

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US (1) US10801039B2 (enExample)
EP (1) EP2861248B1 (enExample)
JP (1) JP6347257B2 (enExample)
KR (1) KR102136437B1 (enExample)
CN (2) CN104582724A (enExample)
AU (2) AU2013274191B2 (enExample)
BR (1) BR112014031133B1 (enExample)
CA (1) CA2876196C (enExample)
ES (1) ES2664069T3 (enExample)
IL (1) IL236148B (enExample)
MA (1) MA37749B1 (enExample)
MX (1) MX364875B (enExample)
NZ (1) NZ703297A (enExample)
RU (1) RU2656187C2 (enExample)
TN (1) TN2014000518A1 (enExample)
WO (1) WO2013188673A2 (enExample)
ZA (1) ZA201409124B (enExample)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
US11053509B2 (en) 2016-04-19 2021-07-06 Csir Plant-produced chimaeric Orbivirus VLPs
WO2017187131A1 (en) * 2016-04-26 2017-11-02 London School Of Hygiene & Tropical Medicine Reoviridae vaccine
CN110049994B (zh) * 2016-12-08 2023-05-02 拜西欧斯（北京）生物技术有限公司 一种缀合物及其应用
CN109897092B (zh) * 2019-04-02 2019-11-19 深圳海关动植物检验检疫技术中心 一种蓝舌病病毒非结构蛋白ns3的可溶制备方法
CN110016466B (zh) * 2019-05-21 2022-09-13 云南省畜牧兽医科学院 特异性检测蓝舌病病毒的单抗及其杂交瘤细胞株和应用
CN110257560B (zh) * 2019-07-23 2023-06-27 深圳海关动植物检验检疫技术中心 一种用于蓝舌病病毒8型检测的试剂、检测方法及应用
CN112375848A (zh) * 2020-12-11 2021-02-19 云南省畜牧兽医科学院 一种蓝舌病病毒血清型鉴定的RT-qPCR检测试剂盒和方法
CN117363588B (zh) * 2023-02-15 2024-08-30 中国农业科学院兰州兽医研究所 一种表达四半胱氨酸标签重组蓝舌病毒的制备方法及应用
CN120271699B (zh) * 2025-04-10 2026-03-31 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一株特异识别蓝舌病毒vp5蛋白的单克隆抗体

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Also Published As

Publication number Publication date
ZA201409124B (en) 2017-05-31
JP6347257B2 (ja) 2018-06-27
MA37749B1 (fr) 2017-05-31
AU2016235036A1 (en) 2016-10-27
IL236148A0 (en) 2015-01-29
CN110628822A (zh) 2019-12-31
BR112014031133B1 (pt) 2023-02-07
TN2014000518A1 (en) 2016-03-30
IL236148B (en) 2019-05-30
MX364875B (es) 2019-05-09
CN104582724A (zh) 2015-04-29
WO2013188673A3 (en) 2014-03-27
CA2876196A1 (en) 2013-12-19
US10801039B2 (en) 2020-10-13
WO2013188673A2 (en) 2013-12-19
MX2014015311A (es) 2016-04-04
RU2015100269A (ru) 2016-08-10
AU2013274191B2 (en) 2016-09-22
CA2876196C (en) 2021-09-21
MA37749A1 (fr) 2016-08-31
NZ703297A (en) 2016-04-29
JP2015525076A (ja) 2015-09-03
ES2664069T3 (es) 2018-04-18
RU2656187C2 (ru) 2018-05-31
AU2013274191A1 (en) 2015-01-22
BR112014031133A2 (enExample) 2017-08-15
HK1209326A1 (en) 2016-04-01
EP2861248A2 (en) 2015-04-22
KR20150036057A (ko) 2015-04-07
US20130337010A1 (en) 2013-12-19
EP2861248B1 (en) 2017-11-15

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