KR102131378B1 - Ep4-매개의 질병 및 질환의 치료에 사용하기 위한 ep4 수용체-선택적 효능제로서의 디플루오로락탐 화합물 - Google Patents

Ep4-매개의 질병 및 질환의 치료에 사용하기 위한 ep4 수용체-선택적 효능제로서의 디플루오로락탐 화합물 Download PDF

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KR102131378B1
KR102131378B1 KR1020157004036A KR20157004036A KR102131378B1 KR 102131378 B1 KR102131378 B1 KR 102131378B1 KR 1020157004036 A KR1020157004036 A KR 1020157004036A KR 20157004036 A KR20157004036 A KR 20157004036A KR 102131378 B1 KR102131378 B1 KR 102131378B1
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difluoro
methyl
hydroxy
oxopyrrolidin
ene
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KR20150036652A (ko
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스테판 더글라스 바렛
프레드 로렌스 시스크
조셉 마이클 콜롬보
그레고리 윌리엄 엔드레스
브래들리 데이비드 제르메인
안드리 코르닐로프
제임스 버나드 크라머
아담 유지블로
커크 엠. 맥시
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카이맨 케미칼 컴파니 인코포레이티드
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KR1020157004036A 2012-07-19 2013-07-19 Ep4-매개의 질병 및 질환의 치료에 사용하기 위한 ep4 수용체-선택적 효능제로서의 디플루오로락탐 화합물 Active KR102131378B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261673514P 2012-07-19 2012-07-19
US61/673,514 2012-07-19
US201361793929P 2013-03-15 2013-03-15
US61/793,929 2013-03-15
PCT/US2013/051263 WO2014015247A1 (en) 2012-07-19 2013-07-19 Difluorolactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated disease and conditions

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Publication Number Publication Date
KR20150036652A KR20150036652A (ko) 2015-04-07
KR102131378B1 true KR102131378B1 (ko) 2020-07-08

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KR1020157004036A Active KR102131378B1 (ko) 2012-07-19 2013-07-19 Ep4-매개의 질병 및 질환의 치료에 사용하기 위한 ep4 수용체-선택적 효능제로서의 디플루오로락탐 화합물
KR1020157004034A Active KR102151578B1 (ko) 2012-07-19 2013-07-19 Ep4-매개의 골 관련 질병 및 질환을 위한 디플루오로락탐 조성물

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