KR102083700B1 - 리포좀 제제 - Google Patents

리포좀 제제 Download PDF

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KR102083700B1
KR102083700B1 KR1020157004549A KR20157004549A KR102083700B1 KR 102083700 B1 KR102083700 B1 KR 102083700B1 KR 1020157004549 A KR1020157004549 A KR 1020157004549A KR 20157004549 A KR20157004549 A KR 20157004549A KR 102083700 B1 KR102083700 B1 KR 102083700B1
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peg
vegf
liposomes
glycerol
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KR20150042215A (ko
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아르투로 산토스
필립 프로스트
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옵코 파마슈티칼스, 엘엘씨
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    • A—HUMAN NECESSITIES
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    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • A61K2039/55511—Organic adjuvants
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
KR1020157004549A 2012-08-21 2013-08-15 리포좀 제제 Active KR102083700B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261691455P 2012-08-21 2012-08-21
US61/691,455 2012-08-21
US201361791693P 2013-03-15 2013-03-15
US61/791,693 2013-03-15
US201361862300P 2013-08-05 2013-08-05
US61/862,300 2013-08-05
PCT/US2013/055084 WO2014031429A2 (en) 2012-08-21 2013-08-15 Liposome formulations

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020207005268A Division KR102177437B1 (ko) 2012-08-21 2013-08-15 리포좀 제제

Publications (2)

Publication Number Publication Date
KR20150042215A KR20150042215A (ko) 2015-04-20
KR102083700B1 true KR102083700B1 (ko) 2020-03-02

Family

ID=50150466

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020157004549A Active KR102083700B1 (ko) 2012-08-21 2013-08-15 리포좀 제제
KR1020207005268A Active KR102177437B1 (ko) 2012-08-21 2013-08-15 리포좀 제제

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020207005268A Active KR102177437B1 (ko) 2012-08-21 2013-08-15 리포좀 제제

Country Status (16)

Country Link
US (2) US10548841B2 (https=)
EP (1) EP2887958B1 (https=)
JP (3) JP6336448B2 (https=)
KR (2) KR102083700B1 (https=)
CN (1) CN104582728A (https=)
AR (1) AR092372A1 (https=)
BR (1) BR112015003658B1 (https=)
CA (2) CA2879597C (https=)
CL (1) CL2015000418A1 (https=)
ES (1) ES2881671T3 (https=)
HU (1) HUE058912T2 (https=)
MX (2) MX363822B (https=)
PL (1) PL2887958T3 (https=)
RU (1) RU2680096C2 (https=)
TW (2) TWI608848B (https=)
WO (1) WO2014031429A2 (https=)

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RU2676303C2 (ru) * 2013-07-11 2018-12-27 Новартис Аг Использование антагониста vegf для лечения ретролентальной фиброплазии
MX2016005505A (es) * 2013-12-19 2016-07-22 Hoffmann La Roche Modulador de la proteina de transferencia de ester de colesterilo (cetp) para usarse en el tratamiento de enfermedades oculares.
EP3145532A4 (en) * 2014-05-02 2018-02-21 Mayo Foundation for Medical Education and Research Individualized treatment of eye disease
KR101778004B1 (ko) 2015-06-22 2017-09-15 (주) 에빅스젠 이마티닙을 유효성분으로 포함하는 안구 건조 질환 예방 및 치료용 약학 조성물
TW201720446A (zh) * 2015-11-13 2017-06-16 Ｏｈｒ製藥公司 非典型脈絡膜新生血管（ｃｎｖ）之大小做為以角鯊胺治療之預測子
SG11202006712XA (en) * 2018-02-06 2020-08-28 Hoffmann La Roche Treatment of ophthalmologic diseases
KR20210096592A (ko) * 2018-08-23 2021-08-05 번스타인, 에릭, 에프 피부 질환을 치료하기 위해 항-vegf 화합물을 도포하고 이러한 화합물을 이용하기 위한 시스템, 장치, 및 방법
CN109180798B (zh) * 2018-09-04 2020-10-27 武汉原生药谷生物医药科技有限公司 一种增强型治疗性抗体及其应用
MY195550A (en) 2018-10-29 2023-01-31 Hoffmann La Roche Antibody Formulation
US20200323882A1 (en) * 2019-03-15 2020-10-15 University Of Rhode Island Board Of Trustees Phlip®-mediated targeting of corticosteroids to diseased tissue
EP3968949A1 (en) 2019-05-16 2022-03-23 OPKO Pharmaceuticals, LLC Triamcinolone acetonide-loaded liposomes topical ophthalmic formulations for prevention of macular thickening and its associated visual outcomes after lens surgery
EP3886946A1 (en) 2019-06-05 2021-10-06 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery
CN113546172A (zh) * 2020-04-24 2021-10-26 山东大学齐鲁医院 Vegf抑制剂在制备治疗缺氧相关疾病药物中的应用
MX2022015656A (es) * 2020-06-15 2023-03-22 Opko Pharmaceuticals Llc Formulaciones oftalmaticas topicas de liposomas cargados con acetonido de triamcinolona como terapia primaria para el edema macular secundario a la oclusion de la vena retiniana de rama.
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
CN116585304B (zh) * 2023-04-25 2024-04-05 四川大学华西医院 一种急性肝损伤保护药物及其制备方法
WO2025146683A1 (en) 2024-01-03 2025-07-10 Lyotropic Delivery Systems Ltd. Topical formulations for delivery of an active compound to the back of the eye
CN119701010B (zh) * 2024-12-25 2025-10-28 山东第一医科大学附属眼科医院(山东省眼科医院) 一种基于中性粒细胞纳米囊泡的抗炎和抗血管双向诱捕联合自发光动力的复合物及其制备方法和应用

Citations (3)

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