KR102067352B1 - 레트로바이러스 생산을 위한 일시적인 형질감염 방법 - Google Patents

레트로바이러스 생산을 위한 일시적인 형질감염 방법 Download PDF

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KR102067352B1
KR102067352B1 KR1020187014239A KR20187014239A KR102067352B1 KR 102067352 B1 KR102067352 B1 KR 102067352B1 KR 1020187014239 A KR1020187014239 A KR 1020187014239A KR 20187014239 A KR20187014239 A KR 20187014239A KR 102067352 B1 KR102067352 B1 KR 102067352B1
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nucleic acid
vector
retroviral
acid vector
cells
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KR20180073624A (ko
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사빈 존슨
셀레스트 팰런트
에이리니 밤바
콘래드 빈크
Original Assignee
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드
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Priority claimed from GBGB1609354.4A external-priority patent/GB201609354D0/en
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material
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    • C12N2800/00—Nucleic acids vectors
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    • C12N2800/00—Nucleic acids vectors
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KR1020187014239A 2015-11-24 2016-11-21 레트로바이러스 생산을 위한 일시적인 형질감염 방법 Expired - Fee Related KR102067352B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1520764.0A GB201520764D0 (en) 2015-11-24 2015-11-24 Transient transfection method for retroviral production
GB1520764.0 2015-11-24
GB1609354.4 2016-05-26
GBGB1609354.4A GB201609354D0 (en) 2016-05-26 2016-05-26 Transient transfection method for retroviral production
PCT/EP2016/078334 WO2017089307A1 (en) 2015-11-24 2016-11-21 Transient transfection method for retroviral production

Publications (2)

Publication Number Publication Date
KR20180073624A KR20180073624A (ko) 2018-07-02
KR102067352B1 true KR102067352B1 (ko) 2020-01-16

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US (2) US10450574B2 (https=)
EP (1) EP3380605A1 (https=)
JP (1) JP7110096B2 (https=)
KR (1) KR102067352B1 (https=)
CN (1) CN108291211A (https=)
AU (1) AU2016359838B2 (https=)
BR (1) BR112018010639A2 (https=)
CA (1) CA3006285A1 (https=)
DE (1) DE102016122317A1 (https=)
FR (1) FR3044017B1 (https=)
IL (1) IL259223B (https=)
IT (1) IT201600117287A1 (https=)
RU (1) RU2749717C2 (https=)
SA (1) SA518391585B1 (https=)
WO (1) WO2017089307A1 (https=)

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CN107624131B (zh) * 2015-05-15 2022-05-17 韦克塔里斯公司 包含至少两种衣壳化的非病毒rna的逆转录病毒颗粒
EP3380604B1 (en) * 2015-11-24 2022-12-28 GlaxoSmithKline Intellectual Property Development Limited Stable cell lines for retroviral production
GB201706121D0 (en) 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Stable cell lines for retroviral production
GB201715052D0 (en) 2017-09-19 2017-11-01 Oxford Genetics Ltd Vectors
EP3633040B1 (en) * 2017-12-22 2023-06-07 Oxford BioMedica (UK) Limited Retroviral vector
GB201816919D0 (en) * 2018-10-17 2018-11-28 Glaxosmithkline Ip Dev Ltd Adeno-associated viral vector producer cell lines
CN110684804B (zh) * 2019-10-15 2023-04-18 上海本导基因技术有限公司 递送外源rnp的慢病毒载体及其制备方法
GB202004371D0 (en) 2020-03-26 2020-05-13 Glaxosmithkline Ip Dev Ltd CAR constructs
GB202005096D0 (en) 2020-04-07 2020-05-20 Glaxosmithkline Modified vectors for production of retrovirus
EP4133057A4 (en) * 2020-04-10 2025-04-16 Southwest Research Institute Three-dimensional bioreactor for viral vector production
EP4308605A1 (en) 2021-03-19 2024-01-24 GlaxoSmithKline Intellectual Property Development Limited Chimeric antigen receptors targeting claudin-3 and methods for treating cancer
CN113373266B (zh) * 2021-06-22 2022-07-01 内蒙古农业大学 一种用于检测绵羊肺腺瘤病毒的荧光rpa引物、试剂盒和检测方法
US12539515B2 (en) 2021-10-28 2026-02-03 Southwest Research Institute Devices for cell separation
EP4698215A1 (en) 2023-04-19 2026-02-25 GlaxoSmithKline Intellectual Property Development Limited Cytotoxicity targeting chimeras for car-t and car-nk cells
WO2024218345A1 (en) 2023-04-21 2024-10-24 Glaxosmithkline Intellectual Property Development Limited Cytotoxicity targeting chimeras for antibody-drug conjugates and bispecific antibodies
WO2026032970A1 (en) 2024-08-07 2026-02-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Cd4-specific chimeric antigen receptor and methods and uses thereof

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WO1999043842A1 (en) 1998-02-26 1999-09-02 Neurovir, Inc. Artificial chromosome constructs containing nucleic acid sequences capable of directing the formation of a recombinant virus
US20060057553A1 (en) * 2000-05-30 2006-03-16 Estuardo Aguilar-Cordova Chimeric viral vectors for gene therapy
WO2002053576A1 (en) 2001-01-05 2002-07-11 The General Hospital Corporation Viral delivery system for infectious transfer of large genomic dna inserts
WO2003087330A2 (en) 2002-04-10 2003-10-23 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Vac-bac shuttle vector system
WO2008099148A1 (en) 2007-02-12 2008-08-21 Ark Therapeutics Ltd. Production of lentiviral vectors

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EP3380605A1 (en) 2018-10-03
RU2749717C2 (ru) 2021-06-16
BR112018010639A2 (pt) 2019-01-22
IT201600117287A1 (it) 2018-05-21
SA518391585B1 (ar) 2020-10-26
US20200063144A1 (en) 2020-02-27
AU2016359838A1 (en) 2018-05-24
DE102016122317A1 (de) 2017-05-24
KR20180073624A (ko) 2018-07-02
CA3006285A1 (en) 2017-06-01
WO2017089307A1 (en) 2017-06-01
IL259223A (en) 2018-07-31
JP7110096B2 (ja) 2022-08-01
RU2018118964A3 (https=) 2020-04-02
FR3044017A1 (fr) 2017-05-26
FR3044017B1 (fr) 2019-05-03
CN108291211A (zh) 2018-07-17
US20170145427A1 (en) 2017-05-25
AU2016359838B2 (en) 2020-08-06
RU2018118964A (ru) 2019-12-26
IL259223B (en) 2022-05-01
JP2019500030A (ja) 2019-01-10
US10450574B2 (en) 2019-10-22

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